心脏康复运动加沙比利缬沙坦钠对慢性心力衰竭患者心功能、肺功能和生活质量的影响

IF 1.5 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Xiaoqi Li, Ping Zhang, Jinlun Cai, Liu Shi, Qiaoyan Ma, Zhongwen Xue
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引用次数: 0

摘要

背景:探讨心脏康复运动联合苏比里尔缬沙坦钠对慢性心力衰竭(CHF)患者心功能、肺功能及生活质量的影响。方法:选择2023年1月~ 2024年12月住院的心力衰竭患者146例,分为对照组(常规治疗+沙比利缬沙坦钠)和研究组(常规治疗+沙比利缬沙坦钠+心脏康复运动)。结果:研究组总有效率高于对照组(P < 0.05)。干预3个月后,研究组左室射血分数水平高于对照组,左室收缩末期内径、左室舒张末期内径、n端前b型利钠肽水平低于对照组(P < 0.01)。干预3个月后,研究组1秒用力呼气量(FEV1)、用力肺活量(FVC)、FEV1/FVC水平均高于对照组(P < 0.01)。干预3个月后,研究组SpO2、PaO2、PaO2/FiO2水平均高于对照组(P < 0.01)。干预3个月后,研究组6分钟步行测试时间延长(P < 0.01)。干预3个月后,研究组MLHFQ评分低于对照组(P < 0.01)。研究组患者再住院率和心血管重大不良事件(MACE)发生率均低于对照组(P < 0.05)。结论:心脏康复运动联合沙比利缬沙坦钠治疗CHF患者有效,可改善CHF患者心功能、肺功能和血气水平,提高运动耐力和生活质量,降低CHF患者再住院率和MACE发生率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of Cardiac Rehabilitation Exercise Plus Sacubitril Valsartan Sodium on Cardiac Function, Lung Function, and Quality of Life in Patients with Chronic Heart Failure.

Background: To explore the impacts of cardiac rehabilitation exercise plus sacubitril valsartan sodium on cardiac function, lung function, and quality of life in chronic heart failure (CHF) patients.

Methods: One hundred and forty-six CHF patients admitted to the hospital from January 2023 to December 2024 were chosen and divided into a control group (conventional treatment + sacubitril valsartan sodium) and a study group (conventional treatment + sacubitril valsartan sodium + cardiac rehabilitation exercise).

Results: The total effective rate of the study group was higher when comparing with the control group (P < .05). The study group had higher left ventricular ejection fraction level as well as lower left ventricular end-systolic diameter, left ventricular end-diastolic diameter, and N-terminal pro B-type natriuretic peptide levels when comparing with the control group after 3 months of intervention (P < .01). The study group had higher forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and FEV1/FVC levels when comparing with the control group following 3 months of intervention (P < .01). The study group had higher SpO2, PaO2, and PaO2/FiO2 levels after 3 months of intervention (P < .01). The study group had longer 6-minute walking test after 3 months of intervention (P < .01). The study group had lower MLHFQ score when comparing with the control group after 3 months of intervention (P < .01). The rate of rehospitalization and incidence of major adverse cardiovascular event (MACE) in the study group were lower than in the control group (P < .05).

Conclusion: Cardiac rehabilitation exercise combined with sacubitril valsartan sodium is effective in treating CHF patients, which improves cardiac function, lung function and blood gas levels, promotes exercise endurance and quality of life, and reduces the rehospitalization rate and MACE incidence in CHF patients.

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来源期刊
Anatolian Journal of Cardiology
Anatolian Journal of Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.30
自引率
7.70%
发文量
270
审稿时长
12 weeks
期刊介绍: The Anatolian Journal of Cardiology is an international monthly periodical on cardiology published on independent, unbiased, double-blinded and peer-review principles. The journal’s publication language is English. The Anatolian Journal of Cardiology aims to publish qualified and original clinical, experimental and basic research on cardiology at the international level. The journal’s scope also covers editorial comments, reviews of innovations in medical education and practice, case reports, original images, scientific letters, educational articles, letters to the editor, articles on publication ethics, diagnostic puzzles, and issues in social cardiology. The target readership includes academic members, specialists, residents, and general practitioners working in the fields of adult cardiology, pediatric cardiology, cardiovascular surgery and internal medicine.
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