Anatomical Science International最新文献_第2页

In vivo flavoprotein functional imaging of the mouse auditory cortex combined with neuroanatomical tracing. 结合神经解剖示踪的小鼠听觉皮层体内黄蛋白功能成像。

IF 1.2 4区医学

Anatomical Science International Pub Date : 2025-06-02 DOI: 10.1007/s12565-025-00854-1

Tetsufumi Ito, Yosuke Hirayama

引用次数: 0

Advanced fixation techniques for high-sensitivity molecular imaging: effectiveness of glyoxal fixation for immunostaining. 用于高灵敏度分子成像的先进固定技术：乙二醛固定免疫染色的有效性。

IF 1.2 4区医学

Anatomical Science International Pub Date : 2025-05-26 DOI: 10.1007/s12565-025-00848-z

Kohtarou Konno, Miwako Yamasaki, Masahiko Watanabe

引用次数: 0

Traditions of Excellence: neuroanatomy at the forefront of the new era. 卓越的传统：新时代最前沿的神经解剖学。

IF 1.2 4区医学

Anatomical Science International Pub Date : 2025-05-22 DOI: 10.1007/s12565-025-00852-3

Kathleen S Rockland

引用次数: 0

An ATAC-seq protocol for neuroscience research. 神经科学研究的ATAC-seq协议。

IF 1.2 4区医学

Anatomical Science International Pub Date : 2025-05-22 DOI: 10.1007/s12565-025-00850-5

Nur Hasan Prince, Misako Hamamura, Yi Zhou, Yuki Fujita

引用次数: 0

Enhancing heart anatomy education in middle schools: virtual reality or tablet-based mobile applications? 加强中学心脏解剖教育：虚拟现实还是基于平板电脑的移动应用？

IF 1.2 4区医学

Anatomical Science International Pub Date : 2025-05-21 DOI: 10.1007/s12565-025-00853-2

Rabia Koca, Hamide Nur Çevik Özdemir

{"title":"Enhancing heart anatomy education in middle schools: virtual reality or tablet-based mobile applications?","authors":"Rabia Koca, Hamide Nur Çevik Özdemir","doi":"10.1007/s12565-025-00853-2","DOIUrl":"10.1007/s12565-025-00853-2","url":null,"abstract":"This study examines the effects of virtual reality (VR) and tablet-based mobile applications (TBMA) in teaching heart anatomy to middle school students. A randomized-controlled trial was conducted in which 84 middle school students were divided into three groups: VR (n = 28), TBMA (n = 28), and control (n = 28). The students' knowledge levels regarding heart anatomy were assessed before and after the applications. In addition, the student's metacognitive awareness and satisfaction levels were measured after the TBMA and VR applications. The participants' opinions regarding the applications were evaluated using qualitative analysis techniques. Descriptive statistics, variance analysis, and t tests were used to analyze quantitative data, and Colaizzi's education method was prepared sevenfold to examine qualitative data. A significant increase in heart anatomy knowledge levels was observed in the distribution of VR and TBMA. However, no significant difference was found between the groups (p > 0.05). In addition, while the metacognitive awareness of heart anatomy was higher in the students in the VR group, the students in the TBMA group were more satisfied with the learning process. Students stated that learning heart anatomy with VR and TBMA methods was fun, informative, and enjoyable and that such applications should be used more in classes. This study reveals that technology-supported teaching methods can positively affect students' learning processes while teaching heart anatomy. More comprehensive research should be conducted with randomized-controlled and mixed-method studies in different age groups and various course subjects to evaluate the sustainability and effectiveness of technology-based applications.","PeriodicalId":7816,"journal":{"name":"Anatomical Science International","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unraveling dynamics of nuclear pore and chromatin via HS-AFM. 核孔和染色质的HS-AFM解析动力学。

IF 1.2 4区医学

Anatomical Science International Pub Date : 2025-05-19 DOI: 10.1007/s12565-025-00849-y

Goro Nishide, Richard W Wong

{"title":"Unraveling dynamics of nuclear pore and chromatin via HS-AFM.","authors":"Goro Nishide, Richard W Wong","doi":"10.1007/s12565-025-00849-y","DOIUrl":"https://doi.org/10.1007/s12565-025-00849-y","url":null,"abstract":"High-speed atomic force microscopy (HS-AFM) enables real-time visualization of biological processes with nanometer-level resolution. This review highlights how HS-AFM has been instrumental in uncovering the dynamic interplay between nuclear pore complexes (NPCs)-which regulate nucleocytoplasmic transport-and genome guardians, including DNA repair proteins and chromatin regulators. Structurally, the NPCs resemble a multi-layered spider cobweb, serving as crucial molecular gatekeepers for maintaining cellular homeostasis, while genome guardians safeguard genomic integrity through DNA repair and chromatin organization. Through HS-AFM, the researchers have gained unprecedented insights into NPC dynamics, revealing their adaptability during nuclear transport, chromatin reorganization, and viral infection. It has also elucidated how genome guardians interact with NPCs, influencing chromatin organization at the nuclear periphery and regulating nucleocytoplasmic trafficking. These discoveries underscore the critical role of NPC-genome interactions in genome stability, gene expression, and nuclear transport, with broad implications for diseases such as cancer, viral infections, and neurodegenerative disorders. In conclusion, HS-AFM has transformed our ability to study the nuclear landscape at the nanoscale, bridging the gap between structural biology and functional genomics. By capturing the real-time molecular dynamics of NPCs and chromatin, HS-AFM provides an essential tool for unraveling the mechanisms that govern nuclear transport and genome regulation. Future advancements in HS-AFM technology, including higher temporal resolution, correlative imaging, and AI-driven analysis, will further expand its potential in biomedical research, paving the way for novel diagnostic and therapeutic strategies.","PeriodicalId":7816,"journal":{"name":"Anatomical Science International","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuromuscular anatomy of common fibular nerve with special focus on fibularis tertius muscle. 腓骨总神经的神经肌肉解剖，特别关注腓骨叔肌。

IF 1.2 4区医学

Anatomical Science International Pub Date : 2025-05-18 DOI: 10.1007/s12565-025-00851-4

Yutaro Natsuyama, Shuang-Qin Yi, Shinichi Kawata, Tomiko Yakura, Zhong-Lian Li, Hidenobu Miyaso, Masahiro Itoh

{"title":"Neuromuscular anatomy of common fibular nerve with special focus on fibularis tertius muscle.","authors":"Yutaro Natsuyama, Shuang-Qin Yi, Shinichi Kawata, Tomiko Yakura, Zhong-Lian Li, Hidenobu Miyaso, Masahiro Itoh","doi":"10.1007/s12565-025-00851-4","DOIUrl":"https://doi.org/10.1007/s12565-025-00851-4","url":null,"abstract":"Fibularis tertius muscle (FT) was first described by Vesalius in 1543 and was subsequently studied in detail by Henle and Hyrtl in the nineteenth century. There has been a controversy over whether FT is a separate beings. With regard to the question, it has been reported that the FT is an independent muscle or a part of the adjacent muscles such as the extensor digitorum longus muscle (EDL) and the extensor digitorum brevis muscle. In this study, to clarify the origin of the FT from the perspective of neuromuscular anatomy, gross and stereomicroscopic dissections and modified Shiler's staining were performed on 48 sides of the lower legs from 25 Japanese cadavers. Of the 48 specimens, 43 specimens (89.6%) had a FT muscle belly, while 5 specimens (10.4%) did not. Most FTs were innervated by distal nerve branches from a common trunk with the EDL. The innervations of the FT and EDL suggest that the FT and EDL were brother muscles, and we proposed here a hypothesis that the FT and EDL originate from a common muscle mass and compete in a tug-of-war for muscle belly components during their development.","PeriodicalId":7816,"journal":{"name":"Anatomical Science International","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unprecedented brachial plexus: a novel variant. 前所未有的臂丛：一个新的变体。

IF 1.2 4区医学

Anatomical Science International Pub Date : 2025-05-17 DOI: 10.1007/s12565-025-00847-0

Abhishek Sharma, Urvashi Singh, Pooja Jain, Anjoo Yadav, Mohit Chauhan, Ankit Srivastava

引用次数: 0

A protocol for multiplex immunofluorescence staining with a fluorescent tyramide signal amplification system, FT-GO. 使用荧光酰胺信号放大系统FT-GO进行多重免疫荧光染色的方案。

IF 1.2 4区医学

Anatomical Science International Pub Date : 2025-05-15 DOI: 10.1007/s12565-025-00846-1

Kenta Yamauchi, Masato Koike, Hiroyuki Hioki

引用次数: 0

Topohistological alignments of ocular/penile organs. 眼/阴茎器官的拓扑组织学排列。

IF 1.2 4区医学

Anatomical Science International Pub Date : 2025-05-13 DOI: 10.1007/s12565-025-00844-3

Gen Yamada, Daiki Hashimoto, Kota Fujimoto, Masanori Nakata, Shinichi Asamura, Yasuhiko Kawakami, Peter Lwigale

引用次数: 0