{"title":"从方法论发展的角度看海马体结构。","authors":"Ling Zhao, Nicola Palomero-Gallagher","doi":"10.1007/s12565-025-00878-7","DOIUrl":null,"url":null,"abstract":"<p><p>This review focuses on the structural organization of the hippocampus and how our understanding of its cellular architecture and functional circuits has been enabled over the last 400 years by the development of methods as varied as the Golgi impregnation, immunohistochemical staining procedures, and polarized light imaging. We provide an outlook on how cutting-edge techniques such as high-resolution imaging and artificial intelligence may continue to shed light on the structural organization of the hippocampus and emphasize the importance of collaborative multidisciplinary efforts including classical neuroanatomists in this endeavor.</p>","PeriodicalId":7816,"journal":{"name":"Anatomical Science International","volume":" ","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Hippocampal architecture viewed through the eyes of methodological development.\",\"authors\":\"Ling Zhao, Nicola Palomero-Gallagher\",\"doi\":\"10.1007/s12565-025-00878-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This review focuses on the structural organization of the hippocampus and how our understanding of its cellular architecture and functional circuits has been enabled over the last 400 years by the development of methods as varied as the Golgi impregnation, immunohistochemical staining procedures, and polarized light imaging. We provide an outlook on how cutting-edge techniques such as high-resolution imaging and artificial intelligence may continue to shed light on the structural organization of the hippocampus and emphasize the importance of collaborative multidisciplinary efforts including classical neuroanatomists in this endeavor.</p>\",\"PeriodicalId\":7816,\"journal\":{\"name\":\"Anatomical Science International\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-08-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Anatomical Science International\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s12565-025-00878-7\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ANATOMY & MORPHOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anatomical Science International","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s12565-025-00878-7","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ANATOMY & MORPHOLOGY","Score":null,"Total":0}
Hippocampal architecture viewed through the eyes of methodological development.
This review focuses on the structural organization of the hippocampus and how our understanding of its cellular architecture and functional circuits has been enabled over the last 400 years by the development of methods as varied as the Golgi impregnation, immunohistochemical staining procedures, and polarized light imaging. We provide an outlook on how cutting-edge techniques such as high-resolution imaging and artificial intelligence may continue to shed light on the structural organization of the hippocampus and emphasize the importance of collaborative multidisciplinary efforts including classical neuroanatomists in this endeavor.
期刊介绍:
The official English journal of the Japanese Association of Anatomists, Anatomical Science International (formerly titled Kaibogaku Zasshi) publishes original research articles dealing with morphological sciences.
Coverage in the journal includes molecular, cellular, histological and gross anatomical studies on humans and on normal and experimental animals, as well as functional morphological, biochemical, physiological and behavioral studies if they include morphological analysis.