Ancient Science of Life最新文献

{"title":"Management of Recurrent Nasal Vestibular Furunculosis by <i>Jalaukāvacaraṇa</i> and Palliative Treatment.","authors":"Amol Sudhakar Kadu,&nbsp;Dhirajsingh Sumersingh Rajput,&nbsp;Sourabh G Deshmukh","doi":"10.4103/asl.ASL_190_15","DOIUrl":"https://doi.org/10.4103/asl.ASL_190_15","url":null,"abstract":"<p><p>Nasal vestibular furunculosis is a common bacterial skin infection among the general population mostly affecting adults and children. It is characterized by acute localized infection of hair follicle in the skin lining of the nasal vestibule caused by <i>Staphylococcus aureus</i>. Immunodeficiency also plays an important role in recurrent skin and soft tissue infections (SSTI) including Nasal furunculosis. Though, the lesion is small, it is extremely painful and tender. Treatment is mostly conservative which consists of warm compresses, analgesics to relieve pain, topical and systemic antibiotics directed against staphylococcus. With rapidly increasing resistance to antibacterial agents, management of these bacterial infections is becoming increasingly difficult. In Ayurveda, it can be correlated with <i>Nāsāruṇaśikhā</i> (Nasal furunculosis). Morphologically, it appears like <i>pīḍikā</i> (Furuncle) which is characterized by <i>Rāgayuktaśotha</i> (inflammation with reddening. <i>Jalaukāvacaraṇa</i> (Leech therapy) is one of the ancient and important parasurgical procedures described in Ayurveda for treatment of various diseases. In this case, a leech has been applied at the affected area. After leech treatment, throbbing pain was reduced in its intensity followed by gradual reduction in swelling and reddening in two days. This case suggests the utility of leech application in Nasal vestibular furunculosis.</p>","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 4","pages":"220-224"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35681794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Study on Successful Ayurvedic Management of a Rare Case of Reiter's Syndrome.","authors":"Vaishali Kuchewar","doi":"10.4103/asl.ASL_89_16","DOIUrl":"https://doi.org/10.4103/asl.ASL_89_16","url":null,"abstract":"<p><p>Reiter's syndrome is a clinical syndrome of arthritis, urethritis, conjunctivitis, and mucocutaneous lesions. Skin and mucosal involvement is observed in about 10% of the cases. A 34-year-old male was brought in severe condition. He had red colored foul smelling maculopapular skin lesions all over body, swollen and painful knee and shoulder joints. History revealed that he was suffering from Reiter's syndrome since 2003. He used to get admitted between the months of February and May every year due to aggravation of symptoms. Every time he was treated with systemic antibiotics, corticosteroids, immunosuppressants and non-steroidal anti-inflammatory drugs. He was successfully treated with external application and internal medication with <i>tikta</i> (bitter) and <i>kaṣāya</i> (astringent) drugs. He got significant relief in skin lesions as well as joint pain and his quality of life was markedly improved. This case study demonstrates that Reiter's syndrome can be well managed with Ayurvedic medicines.</p>","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 4","pages":"225-228"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35681795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Metallurgical Study of <i>Nāga Bhasma</i>.","authors":"Dev Nath Singh Gautam","doi":"10.4103/asl.ASL_206_15","DOIUrl":"https://doi.org/10.4103/asl.ASL_206_15","url":null,"abstract":"<p><strong>Background: </strong>The metal <i>Nāga</i> (Lead) is being used by Indians since ancient times. Its external and internal uses have been described in Caraka, Suśruta and other Ayurvedic <i>Saṃhitā</i>. According to most of the <i>Rasa</i> texts, <i>Nāga Bhasma</i> and its formulations are used in many diseases such as <i>Prameha</i>, <i>Jvara</i>, <i>Gulma</i>, <i>Śukrameha</i> etc.</p><p><strong>Objectives: </strong>In the present study, <i>Nāga Bhasma</i> was prepared by the traditional <i>Puṭa</i> method (TPM) and by the electric muffle furnace <i>Puṭa</i> method (EMFPM) and standardized using Metallographic studies. Doing so helps in the study of the microstructure of <i>Nāga Bhasma</i> and also helps in the identification of the metal particles along with the nature of compound formed during the <i>Māraṇa (Bhasmīkaraṇa)</i> process.</p><p><strong>Setting and design: </strong>Different samples from initial raw material to final product of <i>Nāga Bhasma</i> were collected during the pharmaceutical process (1^st, 30^th and 60^th<i>Puṭa</i>) from both methods i.e. TPM and EMFPM. Samples from both methods were studied using metallographic examination.</p><p><strong>Materials and methods: </strong>The processing of the <i>Nāga Bhasma</i> (<i>ṣaṣṭipuṭa</i>) was done according to <i>Ānanda Kanda</i>[9] Samples from the raw material i.e. <i>Aśodhita Nāga</i> (raw Lead) and that processed after 1^st, 30^th and 60^th Puṭa from both methods i.e. traditional Puṭa method (using heat from burning of cow dung cakes) and electric muffle furnace <i>Puṭa</i> method were taken. They were mounted on self hardening acrylic base. After careful polishing to obtain scratch free surface of product, they were used for metallurgical study.</p><p><strong>Conclusion: </strong>This study shows that traditional <i>Puṭa</i> method may be better than electric muffle furnace <i>Puṭa</i> method because of more homogeneous distribution of Lead sulphide in the <i>Nāga Bhasma</i> which is prepared by traditional method.</p>","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 4","pages":"182-186"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35681838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of <i>Bhrāmarī Prāṇāyāma</i> Practice on Pulmonary Function in Healthy Adolescents: A Randomized Control Study.","authors":"Maheshkumar Kuppusamy, K Dilara, P Ravishankar, A Julius","doi":"10.4103/asl.ASL_220_16","DOIUrl":"10.4103/asl.ASL_220_16","url":null,"abstract":"<p><strong>Context: </strong><i>Prāṇāyāma</i>, the fourth limb of ancient <i>aṣṭāṅga yoga</i> consists of breathing techniques which produce various physiological and psychological effects. Though various types of <i>prāṇāyāma</i> and their effects have been scientifically established, <i>Bhrāmarī prāṇāyāma</i> (Bhr.P) is the one whose effects still remain understated.</p><p><strong>Aims: </strong>The present study was conducted to find the effects of <i>Bhrāmarī prāṇāyāma</i> practice on pulmonary function in healthy adolescents.</p><p><strong>Study design: </strong>Randomized control trial.</p><p><strong>Subjects and methods: </strong>90 healthy adolescents including 32 females and 58 males participated in the study. They were randomly divided into Bhr.P group (<i>n</i> = 45) and Control group (<i>n</i> = 45) by a simple lottery method. Pulmonary function test was done at baseline and at end of 12^th week using RMS Helios spirometry. <i>Prāṇāyāma</i> group students were trained to do Bhr.P as 3 to 4 breaths/min for 5 min followed by 2 min rest. This was one cycle and in this way, they were instructed to do five cycles each time for 45 minutes five days in a week. Control group students were not allowed to practice any kind of exercise throughout the study period.</p><p><strong>Statistical analysis: </strong>Student paired and unpaired T tests were used to analyse the intra group and intergroup differences using R statistical software.</p><p><strong>Results: </strong>A significant (<i>P</i> < 0.05) improvement in all pulmonary function parameters; FVC, FEV1, FEV1/FVC ratio, FEF 25%-75% and PEFR was seen in the Bhr.P group than the control group adolescents. Slow vital capacity (SVC) and Maximum Voluntary Volume (MVV) also showed significant improvement in the <i>prāṇāyāma</i> group.</p><p><strong>Conclusions: </strong><i>Bhrāmarī Prāṇāyāma</i> practice is effective in improving the pulmonary function among the adolescents which could be utilized for further clinical studies.</p>","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 4","pages":"196-199"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35681840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autoimmune Bullous Skin Disease Managed with Ayurvedic Treatment: A Case Report.","authors":"Rahul K Shingadiya,&nbsp;Rohit Sharma,&nbsp;Prashant Bedarkar,&nbsp;Pradeep Kumar Prajapati","doi":"10.4103/asl.ASL_91_16","DOIUrl":"https://doi.org/10.4103/asl.ASL_91_16","url":null,"abstract":"<p><p>Autoimmune bullous diseases are a group of rare, acquired disorders characterized by overlapping features, resistance to treatment, and potential fatality. They need quick and proper management to avoid fatal complications. Ayurveda is found to provide better relief in some autoimmune disorders. Herein, we report a 40-year-old male of autoimmune bullous skin disorder (<i>Visphoṭaka</i>) who failed to respond to allopathic medicines and was subsequently treated with Ayurvedic medicines and achieved complete remission.</p>","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 4","pages":"229-233"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35681799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protective Effect of Standardized Extract of <i>Passiflora incarnata</i> Flower in Parkinson's and Alzheimer's Disease.","authors":"Suvarna P Ingale,&nbsp;Sanjay B Kasture","doi":"10.4103/asl.ASL_231_16","DOIUrl":"https://doi.org/10.4103/asl.ASL_231_16","url":null,"abstract":"<p><strong>Background: </strong>Oxidative stress plays an important role in the pathogenesis of neurodegenerative diseases such as Alzheimer's and Parkinson's disease. Flavonoids exert their antioxidant effects by neutralizing all types of oxidizing radicals including the superoxide and hydroxyl radicals. <i>Passiflora incarnata</i> Linn. (Passifloraceae) is an important plant used in Ayurveda for the treatment of various disorders of the CNS and is a rich source of flavonoids.</p><p><strong>Aim: </strong>In the present study, we investigated the antioxidant, antiparkinsonian, and memory enhancing activity of flavonoid rich n-butanol extract of <i>P. incarnata</i> flowers (BEPIF).</p><p><strong>Materials and methods: </strong>Antioxidant activity was assessed using DPPH and hydrogen peroxide scavenging assay. The antiparkinsonian activity was evaluated using haloperidol induced catalepsy and tacrine induced vacuous chewing movement and memory enhancing activity was assessed using elevated plus maze and object recognition test.</p><p><strong>Statistical analysis: </strong>The results were analyzed by Analysis of Variance test followed by Dunnett's test.</p><p><strong>Results: </strong>Administration of BEPIF decreased transfer latency on day 2 and 9 significantly in elevated plus maze test and showed a significant increase in discrimination index in the object recognition test which is suggestive of its cognitive improvement action. Pretreatment with BEPIF showed a significant reduction in the haloperidol induced catalepsy and the tacrine induced jaw movements which are suggestive of its antiparkinsonian activity. In DPPH and H₂O₂ scavenging assay, BEPIF exhibited significant free radical scavenging activity.</p><p><strong>Conclusions: </strong>It can be concluded that the butanolic extract of <i>P. incarnata</i> flowers has significant antiparkinsonian and cognition enhancing activity which may be associated with its antioxidant potential. Thus, <i>P. incarnata</i> flowers may be employed in treatment of dementia and parkinsonism.</p>","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 4","pages":"200-206"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35681841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Open Label, Randomized, Comparative, Parallel Group, Multicenter, Prospective, Interventional, Clinical Study to Evaluate Efficacy and Safety of \"AHPL/AYTOP/0113\" in Comparison with \"Framycetin Sulphate Cream\" in Acute Wounds.","authors":"Sanjay U Nipanikar,&nbsp;Kamalakar V Gajare,&nbsp;Vidyadhar G Vaidya,&nbsp;Amol B Kamthe,&nbsp;Sachin A Upasani,&nbsp;Vidyadhar S Kumbhar","doi":"10.4103/asl.ASL_52_16","DOIUrl":"https://doi.org/10.4103/asl.ASL_52_16","url":null,"abstract":"<p><strong>Objectives: </strong>The main objective of the present study was to assess efficacy and safety of AHPL/AYTOP/0113 cream, a polyherbal formulation in comparison with Framycetin sulphate cream in acute wounds.</p><p><strong>Methodology: </strong>It was an open label, randomized, comparative, parallel group and multi-center clinical study. Total 47 subjects were randomly assigned to Group-A (AHPL/AYTOP/0113 cream) and 42 subjects were randomly assigned to Group-B (Framycetin sulphate cream). All the subjects were advised to apply study drug, thrice daily for 21 days or up to complete wound healing (whichever was earlier). All the subjects were called for follow up on days 2, 4, 7, 10, 14, 17 and 21 or up to the day of complete wound healing. Data describing quantitative measures are expressed as mean ± SD. Comparison of variables representing categorical data was performed using Chi-square test.</p><p><strong>Results: </strong>Group-A subjects took significantly less (<i>P</i> < 0.05) i.e., (mean) 7.77 days than (mean) 9.87 days of Group-B subjects for wound healing. At the end of the study, statistically significant better (<i>P</i> < 0.05) results were observed in Group-A than Group-B in mean wound surface area, wound healing parameters and pain associated with wound. Excellent overall efficacy and tolerability was observed in subjects of both the groups. No adverse event or adverse drug reaction was noted in any subject of both the groups.</p><p><strong>Conclusion: </strong>AHPL/AYTOP/0113 cream proved to be superior to Framycetin sulphate cream in healing of acute wounds.</p>","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 3","pages":"117-128"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35371186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Need to strategize standardization of Indian systems of medicine","authors":"K. Kumar","doi":"10.4103/asl.ASL_73_18","DOIUrl":"https://doi.org/10.4103/asl.ASL_73_18","url":null,"abstract":"","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"37 1","pages":"1 - 2"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70684982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predatory Conferences in the Field of Ayurveda and Alternative Medicine: Need for Quality Checks.","authors":"P Ram Manohar","doi":"10.4103/asl.ASL_128_17","DOIUrl":"https://doi.org/10.4103/asl.ASL_128_17","url":null,"abstract":"","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 3","pages":"115-116"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35371185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro antioxidant and antimicrobial activities of ethanolic extracts from whole plants of three Impatiens species (balsaminaceae)","authors":"F. Delgado-Rodríguez, Olman Hidalgo, Arlene Loría-Gutiérrez, Nien Weng-Huang","doi":"10.4103/asl.ASL_162_17","DOIUrl":"https://doi.org/10.4103/asl.ASL_162_17","url":null,"abstract":"Context: Plants of Impatiens genus are recognized source of extracts with antioxidant and antimicrobial activity, including I. balsamina(Sanskrit name: Tairini), a plant traditionally used in Asia to treat infections and inflammation. However, there is little information related to activities of whole plant extracts. Aim: To investigate the in vitro antioxidant and antimicrobial activities of the ethanolic extract from whole plant of I. balsamina, I. hawkeri and I. walleriana. Methods: Whole plant material of each species was macerated with ethanol (80% v/v). Phytochemical screening was applied for detection of different metabolites. Total phenolic content (TPC) and total flavonoids content (TFC) were determined using Folin-Ciocalteu and aluminum chloride methods respectively. In vitro antioxidant properties were evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, potassium ferricyanide antioxidant reducing power (PFRAP) and oxygen radical absorbance capacity (ORAC) assays. In vitro antimicrobial activity of extracts was evaluated against Staphylococcus aureus(ATCC 29737), Staphylococcus epidermidis (ATCC 12228), Streptococcus pyogenes (ATCC 19615), Streptococcus pneumoniae (clinical isolate), Pseudomonas aeruginosa (ATCC 9027), Escherichia coli(ATCC 10536), Candida albicans (ATCC 10231) and Aspergillus niger (ATCC 16404) using microdilution assay for minimal inhibitory concentration (MIC) assessment. Statistical Analysis Used: Results were expressed as mean ± SD. Data obtained were analyzed statistically using ANOVA (one-way) followed by Tukey's post hoc test. Correlation analyses were performed using Pearson correlation test. Results: I. hawkeri extract showed the highest phenolic content (TPC: 44.04 mg GAE/g; TFC: 55, 02 mg QE/g) and was the most antioxidant extract. I. balsamina extract was the most active against all Gram positive bacteria (MIC: 2.5-10 mg/ml) tested and> over C. albicans (MIC: 10 mg/ml). This extract also showed the widest antimicrobial spectrum. Conclusions: The evaluated Impatiens whole plant extracts are also promising sources of antioxidant and antimicrobial agents.","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"37 1","pages":"16 - 23"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70684267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}