Ancient Science of Life最新文献

{"title":"Effect of vamana in chronic autoimmune urticaria: A nonresponding case to steroids and cyclosporine","authors":"P. Sharma, B. Sharma","doi":"10.4103/asl.asl_195_17","DOIUrl":"https://doi.org/10.4103/asl.asl_195_17","url":null,"abstract":"Chronic urticaria (CU) is a debilitating disease that considerably affects health-related quality of life. CU symptoms affect a wide range of daily activities, from personal care to sleep/rest, work performance, and social relationships. Physical and emotional functioning is subjectively impaired beyond the severity of the actual disease symptoms. Chronic autoimmune urticaria is caused by anti-FcεRI and less frequently, by anti-immunoglobulin E autoantibodies. Chronic autoimmune urticaria has been found to be associated with autoimmune thyroid disease. A 38-year-old woman having more severe and difficult-to-control urticaria which was a diagnosed case of autoimmune urticaria by AIIMS, New Delhi, underwent vamana (therapeutic emesis) therapy and got satisfactory results. Assessment was done on UAS7 score which reduced from 42 to 0 after 3 months medication. Similarly, CU-Q2oL score reduced from 110 to 24 and Dermatology Life Quality Index score from 30 to 1. This is important because it was a rare case which was not responding to parenteral steroids and cyclosporine.","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"38 1","pages":"20 - 25"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44549179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary healthcare based on the framework of Indian traditional medicine","authors":"S. Kukkupuni","doi":"10.4103/asl.ASL_59_19","DOIUrl":"https://doi.org/10.4103/asl.ASL_59_19","url":null,"abstract":"","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"37 1","pages":"55 - 56"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48602475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angamardhana: A Treatise on Massage Techniques of Ancient India","authors":"B. Praveen","doi":"10.4103/asl.ASL_162_16","DOIUrl":"https://doi.org/10.4103/asl.ASL_162_16","url":null,"abstract":"Massage is considered as one of the oldest therapy used to treat various ailments. It was not only used as a preventive measure but also as a measure to cure disease. Ayurveda being a holistic system of medicine has emphasized the utility of Massage in various conditions. Ayurveda explained Massage as Abhyanga which infers anointing the body. Abhyanga not only prevents and delays normal ageing process but also cure tiredness, musculoskeletal and neurological disorders. Special concentrations are given to Head, Foot and ear massage during process of Abhyanga. Various terminologies are used in Ayurveda to rationalize massage techniques viz Samvahana, Mardhana, Unmardhana and Padaghata. Samvahana is a variety of superficial massage without applying the oil. Mardhana is a varietiy of Massage with oil, applying pressure on a particular part of body. On the contrary, Unmardhana is pressure massage done in direction against to the hair root. Padaghata is a unique variety of massage done using foot. But Ayurveda hardly explains techniques of massage in any context. India has a rich heritage of culture and traditional knowledge in various fields, massage technique is one of them. Traditional massage performed in south India and north India varies a lot via techniques. One of the rare books on traditional massage techniques written by Tiruka has put light on this rich heritage of massage in ancient India.","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 1","pages":"170 - 171"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45182457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of Antimicrobial Potential of Five Herbs used in Ayurveda Practices against <i>Candida albicans, Candida parapsilosis</i> and Methicillin Resistant <i>Staphylococcus aureus</i>.","authors":"Tdcp Gunasekara,&nbsp;Ndm Radhika,&nbsp;K K Ragunathan,&nbsp;Dpp Gunathilaka,&nbsp;M M Weerasekera,&nbsp;Hgsp Hewageegana,&nbsp;L A D M Arawwawala,&nbsp;Ssn Fernando","doi":"10.4103/asl.ASL_179_16","DOIUrl":"https://doi.org/10.4103/asl.ASL_179_16","url":null,"abstract":"<p><strong>Background: </strong>Medicinal plants are an important source of novel antimicrobial agents. Ayurvedic treatment involves the use of a variety of medicinal plants that merit investigation.</p><p><strong>Aims: </strong>To investigate the antimicrobial activity of bark of <i>Pongamia pinnata</i> (L.) Pierre, stem of <i>Rubia cordifolia</i> Linn, leaves of <i>Jasminum officinale</i> Linn, stem of <i>Berberis ceylanica</i> C.K. Schneid. and fruit of <i>Garcina zeylanica</i> Roxb.</p><p><strong>Subjects and methods: </strong>Aqueous and ethanolic extracts of dried bark of <i>Pongamia pinnata</i> (Magul karanda), dried stem of <i>Rubia cordifolia Linn</i> (Welmadata), tender leaves of <i>Jasminum officinale Linn</i> (Jasmine) and dried stem of <i>Berberis ceylanica</i> (Dāruharidrā) were prepared according to standard protocols and tested for antimicrobial activity against five clinical isolates and one standard strain each of <i>Candida albicans</i> (ATCC 10231), <i>Candida parapsilosis</i> (ATCC 22019) and six Methicillin Resistant <i>Staphylococcus aureus</i> (MRSA) clinical isolates using the well diffusion method. Experiments were done in triplicates using well diffusion method. The plant extracts which gave a zone of inhibition in the well diffusion assay were further tested for Minimum Inhibitory Concentrations (MIC).</p><p><strong>Results: </strong>Aqueous and ethanolic extracts of <i>Berberis ceylanica</i> and ethanolic extract of <i>Rubia cordifolia</i> had antimicrobial activity against <i>Candida albicans</i> and <i>Candida parapsilosis</i>. Aqueous and ethanolic extracts of <i>Garcinia zeylanica</i>, and the ethanolic extracts of <i>Jasminum officinale</i>, <i>Rubia cordifolia</i> and <i>Pongamia pinnata</i> had antimicrobial activity against MRSA.</p><p><strong>Conclusions: </strong><i>Berberis ceylanica</i> and <i>Rubia crodifolia</i> had antimicrobial activity against <i>Candida</i> species while <i>Garcinia zeylanica, Jasminum officinale, Rubia crodifolia</i> and <i>Pongamia pinnata</i> had antimicrobial activity against MRSA.</p>","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 4","pages":"187-190"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35681839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antidiabetic Effects of Artemisia Species: A Systematic Review.","authors":"Nikodimos Eshetu Dabe,&nbsp;Adane Teshome Kefale","doi":"10.4103/asl.ASL_87_17","DOIUrl":"https://doi.org/10.4103/asl.ASL_87_17","url":null,"abstract":"<p><strong>Background: </strong>Over the last century, human life style and food habits have drastically changed which lead to various chronic diseases. Diabetes mellitus is one such disease which is causing serious problems to human health. Allopathic drugs are not much effective in handling the disease and its complications. Hence focus has been turned towards the traditional system of medicine. Medicinal plants play an important role in the management of diabetes mellitus.</p><p><strong>Methods: </strong>Experimental studies conducted on species of Artemisia on diabetic animal models and human published since the year 2000 until April, 2017 were reviewed. Each article was critically appraised by two independent reviewers for their methodological quality using the JBIMAStARI tool.</p><p><strong>Result: </strong>A total of 14 studies were included in this review and the blood glucose data obtained from these critically reviewed studies clearly showed that both the aqueous and alcoholic extracts of species of Artemisia produced significant hypoglycemic effects in alloxan, Streptozotocin and high fat diet induced diabetic animals and diabetic humans with different mechanisms of action as compared to standard antidiabetic medications.</p><p><strong>Discussion and conclusion: </strong>The antidiabetic effect of single or multiple doses of aqueous and alcoholic extracts of Artemisia species was due to the active compounds of these plants and they all are effective in lessening the blood glucose level in all of those experimental studies. Despite the presence of known antidiabetic medicines in the pharmaceutical market, therapeutic remedies from these medicinal plants have been utilized with success to treat this disorder and its complications with a relatively less side effects.</p>","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 4","pages":"175-181"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35681837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and Awareness of Pharmacovigilance among Ayurveda Physicians in Himachal Pradesh.","authors":"Rohit Sharma,&nbsp;Jayram Hazra,&nbsp;P K Prajapati","doi":"10.4103/asl.ASL_41_17","DOIUrl":"https://doi.org/10.4103/asl.ASL_41_17","url":null,"abstract":"© 2017 Ancient Science of Life | Published by Wolters Kluwer Medknow Sir, Pharmacovigilance (PV) is a serious concern in India due to frequently observed cases of adverse drug reactions (ADRs),[1] Ayurveda is also facing a dearth of systematic documentation apropos ADRs and safety of its medicines. The possible reasons could be poor awareness of PV and misconception that Ayurveda medicines are devoid of adverse reactions.[2] However it is noteworthy that classical Ayurveda prescribes purely herbal, herbo‐mineral (e.g. Tribhuvanakīrti rasa) and bhasma preparations (callcined metal/minerals), the ADRs may occur if precautions are not taken while manufacturing or administering these medicines.[3,4] Furthermore, doubts regarding long‐term safety of Ayurvedic medicines come up as they may contain metals, minerals or poisonous drugs of Schedule E‐1,[5] and there are reports related to ADRs.[6,7]","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 4","pages":"234-235"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726193/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35681798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical Characterization of an <i>Ayurvedic</i> Herbo-Mineral Formulation - <i>Vasantakusumākara Rasa</i>: A Potential Tool for Quality Assurance.","authors":"Sarada Ota,&nbsp;Arjun Singh,&nbsp;Narayana Srikanth,&nbsp;Bojja Sreedhar,&nbsp;Galib Ruknuddin,&nbsp;Kartar Singh Dhiman","doi":"10.4103/asl.ASL_66_17","DOIUrl":"https://doi.org/10.4103/asl.ASL_66_17","url":null,"abstract":"<p><strong>Background: </strong>Herbo-mineral formulations of Ayurveda contain specified metals or minerals as composition, which have their beneficial effects on biological systems. These metals or minerals are transformed into non-toxic forms through meticulous procedures explained in Ayurveda. Though literature is available on quality aspects of such herbo-mineral formulations; contemporary science is raising concerns at regular intervals on such formulations. Thus, it becomes mandate to develop quality profiles of all formulations that contain metals or minerals in their composition. Considering this, it is planned to evaluate analytical profile of <i>Vasantakusumākara Rasa</i>.</p><p><strong>Objective: </strong>To prepare <i>Vasantakusumākara Rasa</i> as per Standard operating Procedures (SoP) mentioned in classical text and to characterize it chemically using modern analytical techniques.</p><p><strong>Materials and methods: </strong>The drug (<i>Vasantakusumākara Rasa</i>) in three batches was prepared in GMP certified pharmacy. Physico-chemical analysis, Assay of elements and HPTLC were carried out as per API. XRD was conducted using Rigaku Ultima-IV X-ray diffractometer.</p><p><strong>Results: </strong>The analysis shown the presence of Mercury, Tin, Gold, Silver, Iron, Zinc and Calcium etc., and HPTLC revealed presence of organic constituents from plant material. The XRD indicated the presence of cinnabar (mercury sulphide from <i>Rasa Sindhura</i>), cassiterite (tin oxide from <i>Vaṅga Bhasma</i>), massicot (lead oxide from <i>Nāga bhasma</i>) and Magnetite (di-iron oxide from <i>Loha bhasma</i>).</p><p><strong>Conclusion: </strong>The physico chemical analysis reveals that VKR prepared by following classical guidelines is very effective in converting the macro elements into therapeutically effective medicines in micro form. Well prepared herbo-mineral drugs offer many advantages over plant medicines due to their longer shelf life, lesser doses, easy storing facilities, better palatability etc. The inferences and the standards laid down in this study certainly can be utilized as baseline data of standardization and QC.</p>","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 4","pages":"207-214"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35681793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Call for Perseverance and Resources: The Vital Teeth of Key to Success in Ayurveda Research.","authors":"Sujith Subash Eranezhath","doi":"10.4103/asl.ASL_169_17","DOIUrl":"https://doi.org/10.4103/asl.ASL_169_17","url":null,"abstract":"","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 4","pages":"173-174"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35681836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional Consumption of the Fruit Pulp of <i>Chrysophyllum albidum (Sapotaceae)</i> in Pregnancy may be Serving as an Intermittent Preventive Therapy against Malaria Infection.","authors":"Chibueze Peter Ihekwereme,&nbsp;Frances Kaosiso Okoye,&nbsp;Sandra Chinenye Agu,&nbsp;Angus Nnamdi Oli","doi":"10.4103/asl.ASL_208_16","DOIUrl":"https://doi.org/10.4103/asl.ASL_208_16","url":null,"abstract":"<p><strong>Background: </strong>The bark of <i>Chrysophyllum albidum</i> is reported to possess antimalarial property. The fruit pulp of <i>C. albidum</i> consumed by pregnant women of south eastern Nigeria may also possess antimalarial activity. The present preliminary study investigated the antimalarial potential of the pulp juice and seed of <i>C. albidum</i>.</p><p><strong>Methods: </strong>Schizonticidal activity was evaluated using the Peter's 4-day suppressive test. The prophylactic and curative antimalarial activities of the extracts were evaluated in Albino mice inoculated with <i>Plasmodium berghei</i>.</p><p><strong>Results: </strong>The oral acute toxic dose of the pulp extract is beyond 5000 mg/kg. The seed and pulp possess both suppressive and curative properties. The seed extract suppressed early infection by 72.97% and 97.30%, at 500 and 1000 mg/kg, respectively. The pulp juice recorded 72.97% and 81.08%, at 500 and 1000 mg/kg, respectively. At 500 mg/kg dose, the level of parasite control on Day 7 was the same (96.10%) for both seed and pulp.</p><p><strong>Conclusion: </strong>This study demonstrates the presence of antimalarial constituents in the chemically uncharacterized samples (fruit pulp and seed) of <i>C. albidum</i>. Its ethnomedicinal use may be valuable in pregnancy where it may possibly serve as an intermittent preventive therapy against malaria.</p>","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 4","pages":"191-195"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35681791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-anxiety and Anti-depressant Like Effects of <i>Murraya koenigii</i> in Experimental Models of Anxiety and Depression.","authors":"Snigdha Sharma,&nbsp;Shailendra Handu,&nbsp;Ashok Kumar Dubey,&nbsp;Prashant Sharma,&nbsp;Pramod Mediratta,&nbsp;Qazi Mushtaq Ahmed","doi":"10.4103/asl.ASL_75_17","DOIUrl":"https://doi.org/10.4103/asl.ASL_75_17","url":null,"abstract":"<p><strong>Background: </strong>Presence of free radical scavenging activity in <i>Murraya</i><i>koenigii</i>, commonly known as Curry leaves, has been shown in previous studies. Oxidative stress plays an important role in the development of various neurobehavioral disorders including anxiety and depression.</p><p><strong>Aim: </strong>The present study aimed to evaluate the effects of <i>Murraya koenigii</i> in animal models of depression and anxiety.</p><p><strong>Materials and methods: </strong>The effect of incremental doses of <i>Murraya koenigii</i> aqueous leaf extract was evaluated on spontaneous motor activity (SMA), open arm incursions in elevated plus maze, and despair behaviour in forced swim (FST) and tail suspension (TST) tests as compared to control groups in Swiss albino mice.</p><p><strong>Results: </strong><i>Murraya koenigii</i> 300 mg/kg, p.o. (MK300) and 400 mg/kg, p.o. (MK400) reduced the SMA count from 754 ± 64.9 to 540 ± 29 and 295 ± 34 respectively, which was statistically significant. MK300 and MK400 reduced significantly the open arm count from 29 ± 8.6 to 16 ± 7 and 10 ± 3.9, respectively. On FST, MK400 reduced the duration of immobility from 145.5 ± 29 to 91 ± 17.3, which was statistically significant. On TST, MK produced a dose-dependent decrease in the duration of immobility; however, it was statistically significant only with MK400.</p><p><strong>Conclusion: </strong><i>Murraya koenigii</i> aqueous leaf extract reduced the despair behavior in experimental animal models, suggesting an anti-depressant like activity. <i>Murraya koenigii</i> extract also reduced spontaneous locomotor activity in a dose-dependent manner suggesting a sedative and/or anxiolytic effect though there wasn't any anxiolytic effect in the elevated plus maze test.</p>","PeriodicalId":7805,"journal":{"name":"Ancient Science of Life","volume":"36 4","pages":"215-219"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726189/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35681792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}