Angewandte Chemie最新文献_第4页

Outside Back Cover: Tandem Dual-Ratiometric SERS Probe Enables Raman Imaging of Neurological pH Fluctuations in Epilepsy (Angew. Chem. 25/2025) 外后盖：串联双比率SERS探针使癫痫神经pH波动的拉曼成像（新）。化学25/2025)

Angewandte Chemie Pub Date : 2025-05-30 DOI: 10.1002/ange.202511457

Jing Zhao, Yuncan Chen, Yurui Tang, Bohan Li, Qinyue Wang, Prof. Junfeng Wang, Prof. Xihui Gao, Yunle Zhang, Jing Wang, Prof. Zuhai Lei, Prof. Cong Li, Prof. Cong Wang

引用次数: 0

Outside Back Cover: Polyphosphorus Ligand Complexes of Coinage Metals for Multiple Capturing of Intact P4 Tetrahedra (Angew. Chem. 28/2025) 外封底：用于多次捕获完整P4四面体的铸造金属的多磷配体配合物（新）。化学28/2025)

Angewandte Chemie Pub Date : 2025-05-30 DOI: 10.1002/ange.202511458

Claudia Göschl, Eugenia Peresypkina, Barbara Hiltl, Alexander V. Virovets, Gabor Balázs, Manfred Scheer

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Frontispiece: Non-Carbonized Pd Single-Atom Catalyst Supported on Lignin-Functionalized Phenolic Resin for Potent Catalytic Transfer Hydrogenation of Lignin-Derived Aldehydes 扉页：木质素功能化酚醛树脂负载的非碳化Pd单原子催化剂对木质素衍生醛的有效催化转移加氢

Angewandte Chemie Pub Date : 2025-05-30 DOI: 10.1002/ange.202582301

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Outside Front Cover: Unraveling the Complexity of Divalent Hydride Electrolytes in Solid-State Batteries via a Data-Driven Framework with Large Language Model (Angew. Chem. 25/2025) 外封面：解开二价氢化物电解质的复杂性在固态电池通过一个数据驱动的框架与大语言模型。化学25/2025)

Angewandte Chemie Pub Date : 2025-05-28 DOI: 10.1002/ange.202510922

Qian Wang, Fangling Yang, Yuhang Wang, Di Zhang, Ryuhei Sato, Linda Zhang, Eric Jianfeng Cheng, Yigang Yan, Yungui Chen, Kazuaki Kisu, Shin-ichi Orimo, Hao Li

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Inside Back Cover: A Simple Quinoid Building Block for Polymer Semiconductors with Tunable Polarity and High n-Type Thermoelectric Performance (Angew. Chem. 28/2025) 内页后盖：具有可调极性和高n型热电性能的聚合物半导体的简单类醌构建块（新）。化学28/2025)

Angewandte Chemie Pub Date : 2025-05-28 DOI: 10.1002/ange.202510928

Weipeng Sun, Sergio Gámez-Valenzuela, Xiage Zhang, Jin-Woo Lee, Zhicheng Zhong, Peng Wang, Suxiang Ma, Hanqiang Wang, Bumjoon J. Kim, Xugang Guo

引用次数: 0

Helicenes with Four Helical Turns: Dimerization of [13]Helicenes to [27]Helicenoids 四螺旋螺旋：[13]螺旋到[27]螺旋的二聚化

Angewandte Chemie Pub Date : 2025-05-27 DOI: 10.1002/ange.202506328

Matea Sršen, Stephan K. Pedersen, Tomislav Rožić, Arianna Lanza, Michael Pittelkow

{"title":"Helicenes with Four Helical Turns: Dimerization of [13]Helicenes to [27]Helicenoids","authors":"Matea Sršen, Stephan K. Pedersen, Tomislav Rožić, Arianna Lanza, Michael Pittelkow","doi":"10.1002/ange.202506328","DOIUrl":"https://doi.org/10.1002/ange.202506328","url":null,"abstract":"The promise of enhanced circularly polarized luminescence (CPL) from organic molecules has inspired synthetic efforts to prepare elongated multi-layer helicenes. It has proven particularly challenging to synthesize and isolate enantiomerically pure multi-turn helicenes, and consequently, clear guidelines for the molecular design of helicenes to achieve large CPL output remain elusive. We explore the oxidative dimerization of a 2-naphthol-annulated hetero[13]helicene, and observe the formation of two types of structurally distinct hetero[27]helicenes, both with four helical turns, form. With CuIICl(OH)-TMEDA as the oxidant, a symmetric dimer (bi[13]) formed, joining two helicenes with the same helicity in their keto tautomeric forms. Using CuII(OTf)₂ as the oxidant led to an unsymmetrical [27]helicenoid composed by an (M)- and a (P)-enantiomer of the [13]helicene through an unusual coupling between the 1- and 3-positions of the 2-naphthol units. Structural characterization was achieved by NMR spectroscopy and single-crystal (X-ray or electron) diffraction analysis. The enantiomers of this [27]helicenoid were analyzed by electronic circular dichroism (ECD) and CPL measurements. The spectroscopic data were corroborated by DFT calculations, and the intense CPL output is preserved despite the presence of an (M)- and a (P)-helicene in the same molecule. These [27]helicenoids are the first isolated structures that feature helical π-systems with four helical turns.","PeriodicalId":7803,"journal":{"name":"Angewandte Chemie","volume":"137 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ange.202506328","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144624894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metal Complexes Stimulating Immunogenic Pyroptosis as Burgeoning Antitumor Strategy 金属配合物刺激免疫原性焦亡作为新兴的抗肿瘤策略

Angewandte Chemie Pub Date : 2025-05-27 DOI: 10.1002/ange.202507186

Dr. Yue Zheng, Dr. Kun Peng, Prof. Dr. Qian Cao, Prof. Dr. Zong-Wan Mao

{"title":"Metal Complexes Stimulating Immunogenic Pyroptosis as Burgeoning Antitumor Strategy","authors":"Dr. Yue Zheng, Dr. Kun Peng, Prof. Dr. Qian Cao, Prof. Dr. Zong-Wan Mao","doi":"10.1002/ange.202507186","DOIUrl":"https://doi.org/10.1002/ange.202507186","url":null,"abstract":"The exploration of antitumor agents with diverse action mechanisms has become an important focus in both fundamental research and clinical oncology, driven by the need for more effective cancer therapies. Metal complexes, with their versatile chemical, photophysical, and biological properties, represent an ideal class of therapeutic and diagnostic candidates for investigating novel antitumor mechanisms. Recent advances have underscored their unique ability to trigger diverse cell death pathways. Among these, pyroptosis, an inflammatory form of programmed cell death, has garnered substantial attention because of its intrinsic link to antitumor immunity. This minireview focuses on the cutting-edge developments in antitumor metal complexes designed to induce pyroptosis and elucidates their pyroptosis-stimulating mechanisms across chemo-, photo-, sono- and targeted therapeutic modalities. By dissecting the interplay among pyroptosis induction, biological processes, such as inflammasome activation and gasdermin cleavage, and subsequent immune reprogramming, we provide a thorough overview of the action mechanisms of metal complex-based pyroptosis inducers. This understanding has inspired the rational development of novel anticancer metal complexes that can remodel the tumor microenvironment and synergize with immunotherapies.","PeriodicalId":7803,"journal":{"name":"Angewandte Chemie","volume":"137 27","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frontispiece: Photoinduced Electron Transfer Across Phospholipid Bilayers in Anaerobic and Aerobic Atmospheres 前言：厌氧和好氧环境下磷脂双分子层的光诱导电子转移

Angewandte Chemie Pub Date : 2025-05-26 DOI: 10.1002/ange.202582201

引用次数: 0

Stereocontrol in Conformationally Stable C(sp2)─C(sp3) Atropisomers 构象稳定的C（sp2）─C（sp3）反相体的立体控制

Angewandte Chemie Pub Date : 2025-05-24 DOI: 10.1002/ange.202506810

Antoine Domain, Guishun Bai, Dr. Juan-Carlos Castillo, Hassane Moussa Abdraman, Prof. Dr. Stéphane Humbel, Dr. Michel Giorgi, Dr. Jean-Valère Naubron, Sara Chentouf, Prof. Dr. Jean Rodriguez, Dr. Xiaoze Bao, Prof. Dr. Damien Bonne

引用次数: 0

Taxonomy of Chemical Bondings: Opportunities and Challenges 化学键的分类：机遇与挑战

Angewandte Chemie Pub Date : 2025-05-22 DOI: 10.1002/ange.202506525

Prof. Dr. Andrea Pizzi, Prof. Dr. Giancarlo Terraneo, Cristina Lo Iacono, Roberta Beccaria, Dr. Arun Dhaka, Prof. Dr. Giuseppe Resnati

{"title":"Taxonomy of Chemical Bondings: Opportunities and Challenges","authors":"Prof. Dr. Andrea Pizzi, Prof. Dr. Giancarlo Terraneo, Cristina Lo Iacono, Roberta Beccaria, Dr. Arun Dhaka, Prof. Dr. Giuseppe Resnati","doi":"10.1002/ange.202506525","DOIUrl":"https://doi.org/10.1002/ange.202506525","url":null,"abstract":"The concept of the chemical bond is fundamental to chemistry, governing atomic interactions that define all known matter. Despite this central role, the classification and most convenient naming of chemical bonds remain subjects of debate due to the diverse theoretical models and experimental observations. Modelings from quantum mechanical calculations and heuristic principles from experimental observations offer valuable and complementary insights, but sometimes the match and coalescence of these different approaches into a common terminology is not immediate. This paper describes a hierarchical categorization of noncovalent interactions based on the electrophilic atom involved, aligning with IUPAC definitions of hydrogen bonding (HB), halogen bonding (HaB), chalcogen bonding (ChB), and pnictogen bonding (PnB). The resulting taxonomy may avoid some ambiguities that arise from naming interactions based on single chemical/physical features. The proposed categorization that moves from more general and comprehensive terms to more specific and descriptive terms may ensure clarity, comprehensiveness, consistency with periodic trends, and invariancy over evolving understanding of the chemical bonds so that findings can be communicated and stored effectively via both human and machine based protocols.","PeriodicalId":7803,"journal":{"name":"Angewandte Chemie","volume":"137 27","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ange.202506525","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0