Angewandte Chemie最新文献_第4页

Frontispiece: Alkali Metal Cations Impact the Selectivity of Radical-Mediated Electrochemical C─H Chlorination 前言：碱金属阳离子影响自由基介导的电化学C─H氯化选择性

Angewandte Chemie Pub Date : 2025-09-02 DOI: 10.1002/ange.202583602

引用次数: 0

Outside Front Cover: Highly Selective Adsorption of Para-Xylene, Ethylbenzene, and Explicit Exclusion of Ortho-Xylene from Xylene Isomers Using a Pillar-Layered MOF with Tuned Pore Channels (Angew. Chem. 39/2025) 外封面：高选择性吸附对二甲苯，乙苯，并明确排除从二甲苯异构体使用柱状层状MOF调节孔通道（新）。化学39/2025)

Angewandte Chemie Pub Date : 2025-09-01 DOI: 10.1002/ange.202518729

Seonghwan Lee, Amitosh Sharma, Jae Hyeok Lee, Jaewoong Lim, Prof.Dr. Seung Kyu Min, Prof.Dr. Hyungphil Chun, Prof.Dr. Myoung Soo Lah

引用次数: 0

Inside Back Cover: Chirality Makes or Breaks Chemically Driven Self-Assembly (Angew. Chem. 38/2025) 内页后盖：手性使或破坏化学驱动的自组装(新。化学38/2025)

Angewandte Chemie Pub Date : 2025-09-01 DOI: 10.1002/ange.202518660

Lenard Saile, Dr. Kun Dai, Dr. Mahesh D. Pol, Thejus Pramod, Dr. Ralf Thomann, Dr. Charalampos G. Pappas

引用次数: 0

Outside Back Cover: Multisite Proton-Coupled Electron Transfer Facilitates Oxidative Photocatalysis in a Molecular Zr-Based Coordination Compound (Angew. Chem. 38/2025) 外封底：多位点质子耦合电子转移促进了分子zr基配位化合物的氧化光催化（新）。化学38/2025)

Angewandte Chemie Pub Date : 2025-09-01 DOI: 10.1002/ange.202518413

Mercedes Moreno-Albarracín, Alvaro M. Rodriguez-Jimenez, Omar Nuñez, Pablo Garrido-Barros

引用次数: 0

Outside Back Cover: The Importance of Si─ONa─Al Moieties in Fe/ZSM-5 Zeolite Catalysts for Selective Oxidation of Methane to Acetic Acid (Angew. Chem. 40/2025) 外封底：Fe/ZSM-5沸石催化剂中Si─ONa─Al基团对甲烷选择性氧化制乙酸的重要性（英文）化学40/2025)

Angewandte Chemie Pub Date : 2025-09-01 DOI: 10.1002/ange.202518999

Xinyu Zhao, Haibin Yin, Hongfei Lin, Zijin Dai, Xin Chen, Wenlong Wu, Hongliang Li, Bo Wu, Jie Zeng

引用次数: 0

Inside Back Cover: Inter-Nanoparticle FRET for Biosensing: Photophysics Versus Size (Angew. Chem. 39/2025) 内后盖：生物传感的纳米粒子间FRET：光物理与尺寸（新）。化学39/2025)

Angewandte Chemie Pub Date : 2025-09-01 DOI: 10.1002/ange.202518732

Eduard Madirov, Clara Catros, Niko Hildebrandt, Chloé Grazon

引用次数: 0

Stereoselective Self-Assembly of a Topologically Chiral [6]Catenane with 18 Crossings 具有18个交叉的拓扑手性[6]链烷的立体选择性自组装

Angewandte Chemie Pub Date : 2025-09-01 DOI: 10.1002/ange.202515400

Zheng Cui, Li-Yan Hao, Yi-Fan Yuan, Xiao-Peng Xuan, Guo-Xin Jin

{"title":"Stereoselective Self-Assembly of a Topologically Chiral [6]Catenane with 18 Crossings","authors":"Zheng Cui, Li-Yan Hao, Yi-Fan Yuan, Xiao-Peng Xuan, Guo-Xin Jin","doi":"10.1002/ange.202515400","DOIUrl":"https://doi.org/10.1002/ange.202515400","url":null,"abstract":"Mechanically interlocked molecules (MIMs) exhibit unique properties and functions arising from their structural entanglement, features of which are absent in their individual components. However, synthesizing topologically complex architectures, particularly those with topological chirality, remains a significant challenge due to the lack of general methods for controlled entanglement. Herein, we report the stereoselective synthesis of a 24-metal-center topologically chiral [6]catenane featuring 18 crossings (<math></math> link), representing one of the most intricate MIMs constructed to date. This complex architecture was achieved in high yield (71%) via one-step coordination-driven self-assembly of 12 chiral semirigid bidentate ligands and 12 conjugated binuclear half-sandwich organometallic clips. Critically, chirality transfer from enantiopure ligands enabled exclusive formation of topological enantiomer pairs (Rh-1S/Rh-1R), each containing four topologically chiral stereogenic units—three cyclic [3]catenane components and one closed three-link chain component. The self-assembly is synergistically directed by integrated noncovalent interactions (sevenfold π–π stacking, hydrogen bonding, and solvophobic effects), as unambiguously confirmed by single-crystal X-ray diffraction and nuclear magnetic resonance spectroscopy. This design strategy, incorporating tailored noncovalent interaction sites in building blocks, provides a viable approach for synthesizing other structurally complex topologically chiral MIMs.","PeriodicalId":7803,"journal":{"name":"Angewandte Chemie","volume":"137 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145230631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to “Highly Selective Electrocatalytic 1,4-NADH Regeneration Based on Host–Guest Recognition Mediated by Cucurbit[8]Uril on NiO” 对“基于葫芦b[8]Uril介导的主客识别的高选择性电催化1,4- nadh再生”的更正

Angewandte Chemie Pub Date : 2025-09-01 DOI: 10.1002/ange.202508948

引用次数: 0

Protein–Protein Complex Stability Controls Substrate Scope in a β-Ketoacyl-ACP Reductase Specific for Medium Chains 蛋白质-蛋白质复合物稳定性控制中链β-酮酰基- acp还原酶的底物范围

Angewandte Chemie Pub Date : 2025-09-01 DOI: 10.1002/ange.202508316

Samuel J. Andrzejewski, Anika J. Friedman, Kathryn Mains, Annette Thompson, Nathaniel L. Hamel, Banumathi Sankaran, Peter H. Zwart, Michael R. Shirts, Jerome M. Fox

{"title":"Protein–Protein Complex Stability Controls Substrate Scope in a β-Ketoacyl-ACP Reductase Specific for Medium Chains","authors":"Samuel J. Andrzejewski, Anika J. Friedman, Kathryn Mains, Annette Thompson, Nathaniel L. Hamel, Banumathi Sankaran, Peter H. Zwart, Michael R. Shirts, Jerome M. Fox","doi":"10.1002/ange.202508316","DOIUrl":"https://doi.org/10.1002/ange.202508316","url":null,"abstract":"Assembly-line enzymes carry out multistep synthesis of important metabolites by using acyl carrier proteins (ACPs) to shuttle intermediates along defined sequences of active sites. Despite longstanding interest in reprogramming these systems for metabolic engineering and biosynthetic chemistry, the mechanisms underlying their reaction order remain poorly understood and difficult to control. Here we describe a β-ketoacyl-ACP reductase from Pseudomonas putida (PpFabG4) with an unusual selectivity for medium chains and use it to explore the molecular basis of substrate specificity in enzymes that pull intermediates from fatty acid synthesis, a common route to specialized products. X-ray crystallography shows no obvious barriers to short-chain binding. Molecular simulations and supporting mutational analyses indicate that substrate preference arises instead from a weak enzyme–ACP interaction that is stabilized by medium acyl chains but not by short chains. Indeed, mutations that strengthen this interaction for PpFabG4 or weaken it for EcFabG, an Escherichia coli β-ketoacyl-ACP reductase with a broad substrate specificity, can enhance or reduce activity on short-chain substrates by over 100-fold. Our findings show how the stability of enzyme-ACP interactions can control substrate scope in promiscuous enzymes and guide the exchange of intermediates between (and within) assembly-line systems.","PeriodicalId":7803,"journal":{"name":"Angewandte Chemie","volume":"137 40","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145171912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Solvent-Driven Precise Control of Stacking Configurations in Covalent Organic Frameworks for High-Efficiency Photocatalysis 用于高效光催化的共价有机框架中溶剂驱动的层构型精确控制

Angewandte Chemie Pub Date : 2025-08-29 DOI: 10.1002/ange.202512603

Yixue Xu, Fan Qiu, Prof. Yubin Fu, Shun-Feng Li, Xing Su, Prof. Kunquan Hong, Mei-Mei Zhang, Prof. Xin Zhao, Prof. Yuqiao Wang, Prof. Shun-Qi Xu

{"title":"Solvent-Driven Precise Control of Stacking Configurations in Covalent Organic Frameworks for High-Efficiency Photocatalysis","authors":"Yixue Xu, Fan Qiu, Prof. Yubin Fu, Shun-Feng Li, Xing Su, Prof. Kunquan Hong, Mei-Mei Zhang, Prof. Xin Zhao, Prof. Yuqiao Wang, Prof. Shun-Qi Xu","doi":"10.1002/ange.202512603","DOIUrl":"https://doi.org/10.1002/ange.202512603","url":null,"abstract":"Two-dimensional covalent organic frameworks (2D COFs) have emerged as promising photocatalysts due to their high surface areas and precisely tunable physicochemical properties. However, it remains a significant challenge to precisely control over interlayer stacking configurations in 2D COFs, which critically influence charge carrier transport and consequently determine catalytic efficiency. In this study, we demonstrate a solvent-driven strategy to precisely regulate the interlayer stacking configurations of metal-incorporated 2D COFs, successfully achieving both AA eclipsed (COF-TD-AA) and ABC staggered (COF-TD-ABC) configurations. Notably, by modulating the coordination interactions between solvent 1-butanol and Zn2+ (within the COFs), the interactions between the Zn2+ and nitrogen atoms (from imine bonds, pyridine, and triazine units) can be precisely tuned, which leads to the formation of AA or ABC stacked 2D COFs. Interestingly, the ABC-stacked COF-TD-ABC exhibited an extended light absorption and superior charge migration/separation efficiency than those of COF-TD-AA. As a result, when coupled with Pt co-catalysts, COF-TD-ABC achieved a high hydrogen evolution rate up to 10.92 mmol g−1 h−1, representing a ∼3.5-fold enhancement over COF-TD-AA (3.12 mmol g−1 h−1). This work provides a fundamental insight into the stacking-dependent structure-property relationships in COFs, paving the way for the rational design of high-performance COF-based photocatalysts.","PeriodicalId":7803,"journal":{"name":"Angewandte Chemie","volume":"137 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145230887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0