Anais brasileiros de dermatologia最新文献_第8页

Evaluation of dermoscopic findings in patients with cutaneous squamous cell carcinoma according to histopathological subtype and lesion morphology. 根据组织病理学亚型和病变形态评价皮肤鳞状细胞癌患者的皮肤镜表现。

IF 2.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2025-02-13 DOI: 10.1016/j.abd.2024.09.005

Mustafa Ürün, Yıldız Gürsel Ürün, Ömer Faruk Elmas, Nuray Can

{"title":"Evaluation of dermoscopic findings in patients with cutaneous squamous cell carcinoma according to histopathological subtype and lesion morphology.","authors":"Mustafa Ürün, Yıldız Gürsel Ürün, Ömer Faruk Elmas, Nuray Can","doi":"10.1016/j.abd.2024.09.005","DOIUrl":"https://doi.org/10.1016/j.abd.2024.09.005","url":null,"abstract":"<p><strong>Background: </strong>Cutaneous squamous cell carcinoma (cSCC) includes in situ cSCC (Bowen's disease [BD]) and invasive cSCC. By contrast, keratoacanthoma (KA) is a well-differentiated cSCC with self-resolving tendencies. Dermoscopy aids in monitoring vascular and keratin pattern changes to diagnose and track cSCC invasion.</p><p><strong>Objectives: </strong>To examine dermoscopic findings of cSCC according to histopathological differentiation and clinical morphological characteristics.</p><p><strong>Methods: </strong>Clinical and dermoscopic images of 118 cSCCs were retrospectively examined.</p><p><strong>Results: </strong>Compared to other cSCC subtypes, BD more frequently presented with pigmentation (p = 0.028) and a clustered (p = 0.042) or serpiginous (p = 0.006) vascular arrangement. Central keratin plugs were more common in well-differentiated invasive cSCCs (p = 0.021), while white circles surrounding follicles (p < 0.001), ulceration/bleeding (p = 0.001), and red background (p = 0.004) were observed more in poorly differentiated invasive cSCCs. Central keratin plugs (87.5%) and branched vascular arrangements (75%) were observed in patients with nodular KA, with both statistically more frequent than in invasive cSCC (p < 0.001, p = 0.040, respectively). White halos surrounding vessels (p = 0.004) and a clustered vessel arrangement (p = 0.037) were more common in nodular invasive cSCC compared to nodular KA.</p><p><strong>Study limitations: </strong>The number of examined lesions in the subgroups was relatively small.</p><p><strong>Conclusions: </strong>Dermoscopy aids in distinguishing well-differentiated invasive cSCC from poorly differentiated invasive cSCC, distinguishing nodular KA from nodular invasive cSCC, and diagnosing BD. Further studies are needed to identify dermoscopic findings that can distinguish moderately differentiated invasive cSCC from other invasive cSCCs.</p>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and safety of narrowband ultraviolet B phototherapy for prurigo nodularis: a tertiary center experience 窄带紫外线 B 光疗法治疗结节性瘙痒症的有效性和安全性：一家三级医疗中心的经验。

IF 2.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2025-01-01 DOI: 10.1016/j.abd.2024.02.007

Esra Agaoglu, Hilal Kaya Erdogan, Ersoy Acer, Zeynep Nurhan Saracoglu

{"title":"Efficacy and safety of narrowband ultraviolet B phototherapy for prurigo nodularis: a tertiary center experience","authors":"Esra Agaoglu, Hilal Kaya Erdogan, Ersoy Acer, Zeynep Nurhan Saracoglu","doi":"10.1016/j.abd.2024.02.007","DOIUrl":"10.1016/j.abd.2024.02.007","url":null,"abstract":"<div><h3>Background</h3><div>Prurigo nodularis is a chronic pruritic dermatosis and narrowband-UVB (NB-UVB) phototherapy is considered an effective and safe treatment option in patients with multiple comorbidities.</div></div><div><h3>Objective</h3><div>In this study, the authors aimed to evaluate the efficacy and safety of NB-UVB phototherapy in the management of prurigo nodularis and to compare response rates according to lesions localization.</div></div><div><h3>Methods</h3><div>Thirty prurigo nodularis patients who had been treated with NB-UVB phototherapy were included in this study. The data for this study were retrieved retrospectively from patient follow-up forms in the phototherapy unit.</div></div><div><h3>Results</h3><div>NB-UVB phototherapy led to a complete response (CR) in 24 (80%) patients while partial response (PR) was achieved in 6 (20%) patients. Regarding prurigo nodularis localization, the CR rate was statistically higher in those with diffuse and central involvement (p < 0.05). Erythema and/or pruritus were observed in 4 (13.3%) patients with prurigo nodularis.</div></div><div><h3>Study limitations</h3><div>This study is limited because it is single-centered and has a retrospective design.</div></div><div><h3>Conclusions</h3><div>NB-UVB phototherapy is an effective and safe treatment option for prurigo nodularis patients especially those with multiple comorbidities and using several medications. Patients with diffuse and central involvement may respond better to phototherapy than those with peripheral involvement.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 1","pages":"Pages 38-44"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142563791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brazilian experience with oral atenolol in the treatment of infantile hemangiomas 巴西使用口服阿替洛尔治疗婴儿血管瘤的经验。

IF 2.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2025-01-01 DOI: 10.1016/j.abd.2024.03.013

Tauana Ogata Coelho da Rocha, Beatrice Nóbrega Dantas Berenguer, Camila Barreto Vianna Martins, Vanessa Rolim Bessa, Luciana Paula Samorano, Maria Cecília Rivitti-Machado, Zilda Najjar Prado de Oliveira

引用次数: 0

Plaque psoriasis on the tongue: case report 舌头上的斑块状银屑病：病例报告。

IF 2.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2025-01-01 DOI: 10.1016/j.abd.2024.01.008

Lucas Campos Garcia , Nicole Vieira Schwan , Jésus Faria Rosa Júnior , Andrea Machado Coelho Ramos

引用次数: 0

Translation, cultural adaptation and validation of the Brazilian version of the Frontal Fibrosing Alopecia Quality of Life Index (FFA-QLI-BRA) 巴西版额叶纤维性脱发生活质量指数（FFA-QLI-BRA）的翻译、文化适应和验证。

IF 2.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2025-01-01 DOI: 10.1016/j.abd.2024.03.014

Paula Rosa Coutinho Goulart Borges Mariottoni , Leonardo Spagnol Abraham , Leopoldo Duailibe Nogueira Santos , Daniel Fernandes Melo , Rodrigo Pirmez , Paulo Müller Ramos , Hélio Amante Miot

引用次数: 0

Evaluation of how facial sunscreens are applied by the population: an approach beyond the product quantity 评估人们如何使用面部防晒霜：一种超越产品数量的方法。

IF 2.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2025-01-01 DOI: 10.1016/j.abd.2024.04.009

Lucivaldo Fernandes Cruz , Catarina Silva Guimarães , Bianca Lemos Oliveira , Bruna Santana Neves , Caio Ferraz Cabral de Araújo , Maria Clara Botelho de Sousa , Vinicius Rosenbergre dos Santos Carmo , Juliano Geraldo Amaral , Gabriel Azevedo de Brito Damasceno

引用次数: 0

Dermatofibroma: clinicopathological analysis of 239 cases 皮肤纤维瘤：239 个病例的临床病理分析。

IF 2.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2025-01-01 DOI: 10.1016/j.abd.2024.03.012

Dilara İlhan Erdil , Cem Leblebici , Duygu Erdil , Vildan Manav , Vefa Aslı Erdemir , Ayşe Esra Koku Aksu

引用次数: 0

DRESS syndrome: an interaction between drugs, latent viruses, and the immune system DRESS 综合征：药物、潜伏病毒和免疫系统之间的相互作用。

IF 2.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2025-01-01 DOI: 10.1016/j.abd.2023.12.010

Paulo Ricardo Criado , Mayra Ianhez , Hélio Amante Miot , Roberta Fachini Jardim Criado , Carolina Talhari , Paulo Müller Ramos

{"title":"DRESS syndrome: an interaction between drugs, latent viruses, and the immune system","authors":"Paulo Ricardo Criado , Mayra Ianhez , Hélio Amante Miot , Roberta Fachini Jardim Criado , Carolina Talhari , Paulo Müller Ramos","doi":"10.1016/j.abd.2023.12.010","DOIUrl":"10.1016/j.abd.2023.12.010","url":null,"abstract":"<div><div>Drug-induced hypersensitivity syndrome, also known as DRESS syndrome, is a serious and potentially fatal reaction that occurs in response to prolonged use (generally between 14 and 60 days) of certain drugs, and which has no predilection for gender or age group. It is believed that DRESS syndrome has a genetic basis and results from the interaction between metabolites of certain pharmacological groups, reactivation of latent viruses (especially from the <em>Herpesviridae</em> family), and a cellular immune response. The classic manifestation of DRESS syndrome includes a generalized rash accompanied by fever, eosinophilia, lymphadenopathy, and systemic involvement such as hepatitis, nephritis, or pneumonitis. With the continuous increase in the availability of drugs and the aging of the population, there is a favorable scenario for the development of adverse drug reactions. Physicians should be prepared for the early diagnosis of DRESS syndrome, the identification and immediate suspension of the drug involved, and also manage systemic involvement, which may require prolonged immunosuppressive therapy. This article provides an update on the clinical, physiopathological and therapeutic aspects of DRESS syndrome.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 1","pages":"Pages 104-120"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142612414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurothecoma in the tibial region 胫骨部位的神经瘤。

IF 2.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2025-01-01 DOI: 10.1016/j.abd.2024.02.009

Mariana Abdo de Almeida , Neusa Yuriko Sakai Valente , Eduardo César Diniz Macêdo , Bruna Nascimento Arruda Scabello , Patrícia Porto de Oliveira Grossi

引用次数: 0

Red light-emitting diode on skin healing: an in vitro and in vivo experimental study 红色发光二极管对皮肤愈合的影响：体外和体内实验研究。

IF 2.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2025-01-01 DOI: 10.1016/j.abd.2024.02.008

Tuany R. Schmidt , Belkiss C. Mármora , Fernanda T. Brochado , Lucas Gonçalves , Paloma S. Campos , Marcelo L. Lamers , Aurigena A. de Araújo , Caroline A.C.X. de Medeiros , Susana B. Ribeiro , Marco A.T. Martins , Emily F.S. Pilar , Manoela D. Martins , Vivian P. Wagner

{"title":"Red light-emitting diode on skin healing: an in vitro and in vivo experimental study","authors":"Tuany R. Schmidt , Belkiss C. Mármora , Fernanda T. Brochado , Lucas Gonçalves , Paloma S. Campos , Marcelo L. Lamers , Aurigena A. de Araújo , Caroline A.C.X. de Medeiros , Susana B. Ribeiro , Marco A.T. Martins , Emily F.S. Pilar , Manoela D. Martins , Vivian P. Wagner","doi":"10.1016/j.abd.2024.02.008","DOIUrl":"10.1016/j.abd.2024.02.008","url":null,"abstract":"<div><h3>Background</h3><div>The clinical advantages of light-emitting diode (LED) therapy in skin healing and its underlying mechanism remain subjects of ongoing debate.</div></div><div><h3>Objective</h3><div>This study aims to explore the impact of LED therapy on normal skin keratinocytes (HaCaT) and in the repair of full-thickness dorsal wounds in Wistar rats.</div></div><div><h3>Methods</h3><div>HaCaT cell viability (SRB assay) and migration (scratch assay) were assessed under LED therapy, comparing stress conditions (2.5% FBS) with sham irradiation and optimal conditions (10% FBS). In vivo, 50 rats with induced wounds were divided into Sham and LED (daily treatment) groups. Euthanasia occurred at 3, 5, 10, 14, and 21 days for clinical, morphological, oxidative stress (MDA, SOD, and GSH), and cytokine analyses (IL-1β, IL-10, TNF-α).</div></div><div><h3>Results</h3><div>LED therapy significantly enhanced keratinocytes viability compared to sham irradiation, with minimal impact on cell migration. Clinical benefits were prominent on day 10, influencing inflammation progression and resolution on days 3 and 10. Re-epithelization remained unaffected. Reduced MDA and increased GSH levels were observed throughout, while SOD levels varied temporally. Notably, on day 10, LED significantly decreased IL-1β, IL-10, and TNF-α.</div></div><div><h3>Study limitations</h3><div>Although translational, clinical trial confirmation of observed benefits is warranted.</div></div><div><h3>Conclusions</h3><div>LED therapy expedites cutaneous healing in the experimental model, primarily modulating inflammation and enhancing antioxidant activity.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 1","pages":"Pages 54-62"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142612430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0