Nathalia Hoffmann Guarda Aguzzoli , Ana Laura Bueno , Yağmur Halezeroğlu , Renan Rangel Bonamigo
{"title":"Skin cancer after heart transplantation: a systematic review","authors":"Nathalia Hoffmann Guarda Aguzzoli , Ana Laura Bueno , Yağmur Halezeroğlu , Renan Rangel Bonamigo","doi":"10.1016/j.abd.2024.05.004","DOIUrl":"10.1016/j.abd.2024.05.004","url":null,"abstract":"<div><h3>Background</h3><div>Cancer is an important cause of morbidity and mortality after solid organ transplants. Skin cancer is the most prevalent non-lymphoid malignancy occurring during heart transplantation follow-up. Due to the complexity of immunosuppressive therapy and the high prevalence and incidence of skin cancer in this population, dermatologists play an important role in the short and long-term follow-up of heart transplant recipients.</div></div><div><h3>Objectives</h3><div>The goal of this study is to present data from a systematic literature review focusing on the occurrence of skin cancer in patients who have undergone heart transplantation.</div></div><div><h3>Methods</h3><div>The authors conducted a systematic review of the literature in the EMBASE and PubMed databases from August to September 2021 to investigate the incidence of skin cancer in heart transplant patients. The authors selected retrospective and prospective cohort studies presenting data on the frequency of skin cancer in patients following heart transplantation. Exclusion criteria included articles that did not stratify the organ transplant type and studies that did not evaluate the frequency of skin cancer in the specific population.</div></div><div><h3>Results</h3><div>Based on the search strategy, the authors found 2589 studies, out of which 37 were eligible for inclusion in this study. Provided data are from 20 different countries, over the period 1974 to 2015. Incidence of non-melanoma skin cancer (NMSC) ranges from 0.97% to 52.8%. The incidence of squamous cell carcinoma (SCC) ranges from 1.19% to 89% and the incidence of basal cell carcinoma (BCC) ranges from 2% to 63%. Malignant Melanoma (MM) incidence ranges from 0.94% to 4.6%</div></div><div><h3>Study limitations</h3><div>The analysis involved an exclusive focus on heart transplant patients, and the statistical analysis of the sample may have been hampered. The significant heterogeneity among the studies emerged as a challenge during the analysis of the results. Furthermore, the study is limited by variations in follow-up periods among the included studies.</div></div><div><h3>Conclusion</h3><div>Although gathering methodologically heterogeneous data, this systematic review was able to show the epidemiological importance of skin cancer in heart transplant patients. This study reinforces the important role dermatologists play in the short and long-term follow-up of heart transplant patients.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 1","pages":"Pages 63-86"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Facial cutaneous Rosai-Dorfman disease treated with pulsed dye laser: a case report and literature review","authors":"Qin-Xiao Wang, Si-Yu Luo, Kai-Yi Zhou, Sheng Fang","doi":"10.1016/j.abd.2024.05.002","DOIUrl":"10.1016/j.abd.2024.05.002","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 1","pages":"Pages 204-207"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745284/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142612415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claudia Schroder , Matías Gárate , Diego Orlandi , Ligia Aranibar , Francisco Silva
{"title":"Clinical and epidemiological characterization of demodicosis cases in the pediatric population at the Hospital Clinic of the University of Chile (2013‒2020)","authors":"Claudia Schroder , Matías Gárate , Diego Orlandi , Ligia Aranibar , Francisco Silva","doi":"10.1016/j.abd.2023.10.008","DOIUrl":"10.1016/j.abd.2023.10.008","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 1","pages":"Pages 145-147"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucas Campos Garcia , João Renato Vianna Gontijo , Flávia Vasques Bittencourt
{"title":"Plantar acral melanoma: epidemiological, clinical, dermoscopic and histopathological features. A Brazilian cohort","authors":"Lucas Campos Garcia , João Renato Vianna Gontijo , Flávia Vasques Bittencourt","doi":"10.1016/j.abd.2024.03.006","DOIUrl":"10.1016/j.abd.2024.03.006","url":null,"abstract":"<div><h3>Background</h3><div>Acral melanomas (AM) are rare and approximately two-thirds of them occur on the soles of the feet beeing more prevalent in black and Asian individuals. Data on this subtype of melanoma are scarce in the Brazilian population.</div></div><div><h3>Objectives</h3><div>To describe and correlate the epidemiological, clinical, dermoscopic, and histopathological features of AM a.</div></div><div><h3>Methods</h3><div>Single-center, retrospective and cross-sectional study, evaluating data from a 15-year period.</div></div><div><h3>Results</h3><div>A total of 48 cases were included. Mean age was 62.54 years, with a predominance of women (62.5%). The percentage of amelanotic melanomas was higher among lighter skin patients (20% × 7.7%). Polychromia was the most prevalent finding (94.4%). The parallel ridge pattern (PRP) had a prevalence of 78% and a serrated pattern was associated with lower Breslow thickness (p = 0.041). Ulceration present on histopathological (p = 0.013) or dermoscopic (p = 0.047) evaluation was associated with greater Breslow thickness.</div></div><div><h3>Study limitations</h3><div>Retrospective study with loss of data.</div></div><div><h3>Conclusion</h3><div>Amelanotic tumors were more prevalent in ligther phototypes (20% × 7.7%). Polychromia was the most prevalent finding (94.4%) and ulceration observed on clinical or histopathological evaluation was associated with higher Breslow thickness (p = 0.013 and 0.047).</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 1","pages":"Pages 45-53"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephano Cedirian , Ludmila Prudkin , Bianca Maria Piraccini , Julia Santamaria , Jaime Piquero-Casals , David Saceda-Corralo
{"title":"The exposome impact on hair health: etiology, pathogenesis and clinical features ‒ Part I","authors":"Stephano Cedirian , Ludmila Prudkin , Bianca Maria Piraccini , Julia Santamaria , Jaime Piquero-Casals , David Saceda-Corralo","doi":"10.1016/j.abd.2024.07.003","DOIUrl":"10.1016/j.abd.2024.07.003","url":null,"abstract":"<div><div>Human hair, particularly on the scalp, serves as a significant aspect of social identity and well-being. The exposome, encompassing both intrinsic and extrinsic factors, plays a fundamental role in hair weathering. Intrinsic factors include genetic predispositions and physiological changes within the body, while extrinsic factors comprise environmental exposures such as UV radiation, pollution, humidity, temperature variations, lifestyle choices, and chemical treatments. These elements collectively contribute to the cumulative damage experienced by hair over time. Understanding the comprehensive impact of the exposome on hair health and hair aging necessitates an exploration of various environmental conditions, lifestyle factors, and technical artifacts. Despite advancements in research, the intricate mechanisms underlying the exposome influence on hair remain incompletely understood. Through a comprehensive review of current literature and emerging research findings, this study aims to enhance the understanding of exposome impact on hair health.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 1","pages":"Pages 131-140"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariany Lima Rezende , Ana Luiza Castro Fernandes Villarinho , Maria das Graças Mota Melo , Clarissa Vita Campos
{"title":"Allergic contact dermatitis to lettuce","authors":"Mariany Lima Rezende , Ana Luiza Castro Fernandes Villarinho , Maria das Graças Mota Melo , Clarissa Vita Campos","doi":"10.1016/j.abd.2024.04.006","DOIUrl":"10.1016/j.abd.2024.04.006","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 1","pages":"Pages 172-174"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142563690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of long term efficacy and cost-effectiveness of omalizumab in 150 mg and 300 mg doses in patients with chronic spontaneous urticaria","authors":"Fikriye Kalkan, Sait Yeşillik, Fevzi Demirel, Ezgi Sönmez, Yasemin Balaban, Mustafa İlker İnan, Özgür Kartal","doi":"10.1016/j.abd.2024.02.006","DOIUrl":"10.1016/j.abd.2024.02.006","url":null,"abstract":"<div><h3>Background</h3><div>Chronic spontaneous urticaria (CSU) is a clinical condition that affects patients quality of life. Omalizumab is preferred in antihistamines resistant CSU cases. Urticaria activity score-7 (UAS-7) is a scale that shows the severity of the disease.</div></div><div><h3>Objectives</h3><div>The authors aimed to compare the long-term (60 months) efficacy and side effects of 150 mg and 300 mg doses of omalizumab in patients with CSU.</div></div><div><h3>Methods</h3><div>108 patients followed up at the clinic with the diagnosis of CSU were included. Omalizumab was started in patients who were resistant to conventional CSU treatment. Two groups were formed to receive 150 mg and 300 mg doses of omalizumab. Urticaria activity score (UAS-7), antihistamine usage, time to achieve disease-free stage, relapse after treatment, and side effects of omalizumab treatment were compared in the two groups.</div></div><div><h3>Results</h3><div>There were no statistically significant differences between the groups regarding basal characteristics and laboratory findings. Average follow-up time was sixty months. UAS-7 scores were similar in the follow-up. There were no adverse events in both groups.</div></div><div><h3>Study limitations</h3><div>Retroactive design and single-center nature to reach a more significant number of patients. Lack of patients receiving the lowest dose 75 mg and the highest dose 600 mg of omalizumab. Absence of total body mass indexes of all patients. Besides, the use of distinct drugs may contribute to non confident results and is another limitation of this study.</div></div><div><h3>Conclusion</h3><div>Since there is no significant difference between 150–300 mg omalizumab doses regarding long-term treatment efficacy and side effects in CSU patients, starting treatment with a 150 mg dose may be suitable. In patients who do not respond to 150 mg, the omalizumab dose can be increased to 300 mg. It will prevent unpredictable dose and time-dependent complications and will be a cost-effective approach even in strong economies.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 1","pages":"Pages 31-37"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745225/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heitor de Sá Gonçalves , Carlos Baptista Barcaui , Francisca Regina Oliveira Carneiro , Márcio Soares Serra , Rosana Lazzarini , Fabiane Andrade Mulinari Brenner
{"title":"The Brazilian Society of Dermatology on the centennial of the Anais Brasileiros de Dermatologia","authors":"Heitor de Sá Gonçalves , Carlos Baptista Barcaui , Francisca Regina Oliveira Carneiro , Márcio Soares Serra , Rosana Lazzarini , Fabiane Andrade Mulinari Brenner","doi":"10.1016/j.abd.2024.09.001","DOIUrl":"10.1016/j.abd.2024.09.001","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 1","pages":"Pages 1-2"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}