Anais brasileiros de dermatologia最新文献

{"title":"Latin American consensus on psoriasis severity classification","authors":"Angela María Londoño-García ,&nbsp;Juan Raúl Castro-Ayarza ,&nbsp;Manuel Darío Franco Franco ,&nbsp;Cesar Fernando González Ardila ,&nbsp;Gabriel Magariños ,&nbsp;Enrique Salvador Rivas Zaldívar ,&nbsp;Susan Martínez ,&nbsp;Linda Ibatá ,&nbsp;Julieth Carolina Castillo ,&nbsp;Paola Jimena Cárdenas Rojas ,&nbsp;Evelyn Giuliana Castro Vargas ,&nbsp;Claudia Romina Contreras ,&nbsp;Carolina Ivette Cortes Correa ,&nbsp;Claudia de la Cruz Fernández ,&nbsp;Andrés Chavarriaga Restrepo ,&nbsp;Cristina Mariela Echeverria ,&nbsp;André Vicente Esteves de Carvalho ,&nbsp;Benjamín Hidalgo Matlock ,&nbsp;Enrique Loayza ,&nbsp;Matías Rafael Maskin ,&nbsp;Fernando Valenzuela","doi":"10.1016/j.abd.2024.09.010","DOIUrl":"10.1016/j.abd.2024.09.010","url":null,"abstract":"<div><h3>Background</h3><div>There are different classifications of psoriasis based on its clinical presentation, impact on quality of life, requirements for specific treatments, and other patient- or physician-reported outcomes. However, the lack of unified definitions has led to the severity of the disease being underestimated. Standardizing the classification of psoriasis will promote a better approach to the disease and facilitate care by professionals.</div></div><div><h3>Objective</h3><div>To present a consensus of experts in Latin America regarding the classification of psoriasis severity, based on the best available evidence and applicable to current medical practice in the region.</div></div><div><h3>Methods</h3><div>An independent methodological team, together with a group of clinical dermatologists representatives from different Latin American countries, developed a consensus with a modified Delphi methodology based on a systematic review of the literature. This consensus includes the classification of psoriasis, tools to define the severity of psoriasis, and other considerations in evaluating patients with psoriasis.</div></div><div><h3>Results</h3><div>Fifteen statements were formulated aimed at classifying the severity of cutaneous psoriasis and other forms of the disease, as well as tools to assess and define the severity of psoriasis and therapy considerations. Additionally, the consensus addresses implementation considerations.</div></div><div><h3>Conclusion</h3><div>The results of this consensus constitute a solid basis for a standard classification terminology for the varied clinical forms of psoriasis and their therapeutic implications. The importance of maintaining a personalized therapeutic approach, adjusted to each country's available resources and administrative realities, is highlighted.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 3","pages":"Pages 539-547"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pruritus in atopic dermatitis: a cross-sectional study of adult patients from a tertiary university hospital in São Paulo, Brazil.","authors":"Georgia Biazus Soares, Raquel Leão Orfali, Beatriz Lacerda Averbach, Qai Ven Yap, Gil Yosipovitch, Valeria Aoki","doi":"10.1016/j.abd.2024.09.006","DOIUrl":"https://doi.org/10.1016/j.abd.2024.09.006","url":null,"abstract":"<p><strong>Background: </strong>Chronic pruritus is the defining symptom of atopic dermatitis (AD). Although AD is common in Latin America, there is little data regarding pruritus intensity, characteristics, and effects on quality of life in this population.</p><p><strong>Objective: </strong>This cross-sectional study aimed to evaluate pruritus in 91 patients with AD at a tertiary university hospital in São Paulo, Brazil. Patients aged 14‒65-years old were included in this study.</p><p><strong>Methods: </strong>Patients completed the Itch Questionnaire, the ItchyQoL, and the POEM questionnaires and were asked to rate their itch severity using a 10-point peak pruritus Numerical Rating Scale (NRS). AD severity was assessed via the EASI and the vIGA-AD.</p><p><strong>Results: </strong>The mean age was 29.68 ± 12.87years, and 56.0% of patients were White. 97.8% of patients were currently experiencing pruritus with an average NRS of 7.32 ± 2.22. Patients had associated bleeding (71.4%), heat sensation (63.7%), and pain (54.9%). Worsening factors included stress (93.4%), dry skin (91.2%), and sweat (75.8%). The mean total ItchyQoL score was 78.93 ± 17.20. Female gender was significantly associated with a higher total ItchyQoL score (p = 0.009). Pruritus on the neck, foot, and whole body was associated with higher total ItchyQoL scores in adjusted models (p < 0.05). The EASI, vIGA-AD, and POEM were moderately correlated with itch intensity (r = 0.434, 0.406, and 0.610) and total ItchyQoL score (r = 0.425, 0.436, and 0.631).</p><p><strong>Study limitations: </strong>The predominantly White population cohort may not be representative of the diverse AD phenotypes in the Brazilian patient population. Children under the age of 14 and adults over the age of 65 were excluded from the population cohort. Furthermore, patients included in the study may suffer from other non-dermatological diseases that cause itch, which may influence the outcomes oberserved.</p><p><strong>Conclusions: </strong>Patients with AD in Brazil experience significant pruritus that impacts their quality of life. Gender, body location of itch, associated pain, and stress should all be taken into consideration when evaluating AD patients with pruritus.</p>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eccrine poroma versus eccrine porocarcinoma: a comparative study of clinicopathological features","authors":"Qin-Xiao Wang ,&nbsp;Si-Yu Luo ,&nbsp;Kai-Yi Zhou ,&nbsp;Xiao Shen ,&nbsp;Sheng Fang","doi":"10.1016/j.abd.2024.04.010","DOIUrl":"10.1016/j.abd.2024.04.010","url":null,"abstract":"<div><h3>Background</h3><div>Eccrine porocarcinoma (EPC) is a rare cutaneous neoplasm, commonly arising from its benign counterpart, eccrine poroma (EP), but potential unrevealed clinicopathological differences between them are not well understood.</div></div><div><h3>Objectives</h3><div>This study aimed to identify clinicopathological features of EP and EPC and describe the factors that may be associated with the malignant transformation of EP by comparing the two groups.</div></div><div><h3>Methods</h3><div>A total of 37 cases of EP and 22 cases of EPC diagnosed between January 2017 and June 2023 were retrospectively reviewed, and the clinical and histopathological characteristics were compared using statistical methods.</div></div><div><h3>Results</h3><div>Clinical and histopathologic data such as age, gender, site, clinical presentation, and histopathologic characteristics were collected. The EPC group was more common in older patients, with more cases located in exposed areas, and the patients with EPC had larger lesions with a higher incidence of ulceration. Histopathological features showed significant differences in tumor architecture, ulceration, squamous differentiation, spindle cell changes, central necrosis, and diffuse inflammatory infiltration between the two groups.</div></div><div><h3>Study limitations</h3><div>This study has limitations due to a small number of cases with potential experimental bias.</div></div><div><h3>Conclusion</h3><div>The clinicopathological features of EP and EPC were compared in this study and the results may assist clinicians in diagnosis and management of these tumors by helping to identify potential factors associated with the malignant transformation of EP.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 253-259"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The exposome impact on hair health: non-pharmacological management. Part II⋆","authors":"Stephano Cedirian ,&nbsp;Ludmila Prudkin ,&nbsp;Juan Antonio Santana ,&nbsp;Jaime Piquero-Casals ,&nbsp;David Saceda-Corralo ,&nbsp;Bianca Maria Piraccini","doi":"10.1016/j.abd.2024.08.006","DOIUrl":"10.1016/j.abd.2024.08.006","url":null,"abstract":"<div><div>Hair holds a significance that surpasses mere aesthetics, as it plays a pivotal role in our social interactions and contributes significantly to the definition of our self-esteem. Central to this understanding is the concept of the exposome, which encompasses intrinsic elements like genetics and physiological changes, as well as extrinsic factors such as UV radiation, pollution, lifestyle choices, and chemical treatments. These factors may significantly impact hair health and hair aging. Expanding upon the groundwork laid by the first part of this research (Cedirian et al., 2024), this study aims to deepen our understanding of exposome influence on hair. Specifically, through a narrative review of current literature, this second part endeavors to provide non-pharmacological treatment solutions and effective strategies to mitigate the negative impact of the exposome on hair health.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 322-327"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prurigo pigmentosa related to a popular diet trend: the ketogenic diet","authors":"Cristina Barrabés-Torrella ,&nbsp;Ana Iglesias-Plaza ,&nbsp;María Teresa Fernández-Figueras ,&nbsp;Montse Salleras-Redonnet","doi":"10.1016/j.abd.2024.08.005","DOIUrl":"10.1016/j.abd.2024.08.005","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 370-371"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143609302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First case of hyperpigmentation in vitiligo after use of methimazole in a patient with Graves' disease","authors":"Nicolau Lima ,&nbsp;Meyer Knobel ,&nbsp;Mayara Chinelatto ,&nbsp;Maria Victória Quaresma","doi":"10.1016/j.abd.2024.06.006","DOIUrl":"10.1016/j.abd.2024.06.006","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 395-398"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143057792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multifocal pyoderma gangrenosum mimicking disseminated cutaneous leishmaniasis ‒ a diagnostic challenge","authors":"Ana Flávia Mundim Ramos ,&nbsp;Cristiane Botelho Miranda Cárcano ,&nbsp;Davi Carvalho Brito ,&nbsp;Daniele Moraes Losada ,&nbsp;Cristina Alessi da Rocha ,&nbsp;Bruno Augusto Alvares","doi":"10.1016/j.abd.2024.04.013","DOIUrl":"10.1016/j.abd.2024.04.013","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 367-369"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Omalizumab treatment in delayed pressure urticaria as confirmed by stimulation test","authors":"Cesare Ariasi,&nbsp;Gabriele Perazzolli,&nbsp;Luca Rubelli,&nbsp;Alessandro Fraghì,&nbsp;Piergiacomo Calzavara-Pinton","doi":"10.1016/j.abd.2024.06.008","DOIUrl":"10.1016/j.abd.2024.06.008","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 399-400"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Livedoid vasculopathy, calciphylaxis, and Martorell’s hypertensive ulcer: update on ischemic ulcers due to impaired microcirculation of the lower limbs","authors":"Priscila Neri Lacerda ,&nbsp;Lucas Campos Garcia ,&nbsp;Izabelle Ferreira da Silva Mazeto ,&nbsp;Hélio Amante Miot ,&nbsp;Luciana Patricia Fernandes Abbade","doi":"10.1016/j.abd.2024.09.004","DOIUrl":"10.1016/j.abd.2024.09.004","url":null,"abstract":"<div><div>Ischemic ulcers due to compromised microcirculation of the lower limbs cause painful ulcers that represent a challenge for the correct diagnosis and treatment. Livedoid vasculopathy, calciphylaxis, and Martorell’s hypertensive ischemic ulcer are part of this group and present some similarities due to microvascular occlusive impairment. They are often misdiagnosed as inflammatory ulcers such as pyoderma gangrenosum and vasculitis. This review discusses the pathophysiology, risk factors, clinical aspects, differential diagnoses, histopathology, and presents a therapeutic update of livedoid vasculopathy, calciphylaxis, and Martorell’s ulcer. Although they are less frequent causes of chronic ulcers, a correct diagnosis is essential to reduce the chance of erroneous therapies that may impact morbidity and mortality related to these conditions.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 215-227"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal analysis of hospital morbidity and mortality due to skin cancer from 2012 to 2022: comparison with demographic and geographic factors in Brazilian states","authors":"Lucía Alejandra Bolis Castro,&nbsp;Maria Cecília Aires Martins,&nbsp;Kelser de Souza Kock","doi":"10.1016/j.abd.2024.05.008","DOIUrl":"10.1016/j.abd.2024.05.008","url":null,"abstract":"<div><h3>Background</h3><div>Skin cancer is the most common neoplasm among Brazilians, accounting for 31.3% of all cancer cases in the country.</div></div><div><h3>Objectives</h3><div>To analyze the longitudinal morbimortality of skin cancer and compare it with the latitude and the prevalence of white skin color in each federative unit of the country.</div></div><div><h3>Methods</h3><div>An ecological observational study was carried out using data from the Hospital Information System (SIH) and the Mortality Information System (SIM).</div></div><div><h3>Results</h3><div>In Brazil, morbidity rates (per 100,000 inhabitants) increased from 14.88 to 27.69 (p &lt; 0.05) when comparing the years 2012 and 2022, whereas the mortality rates (per 100,000 inhabitants) increased from 0.35 to 0.54 (p &lt; 0.05) during the same period. Furthermore, most states showed an increase in morbimortality rates. Concerning race/ethnicity, individuals with white skin had the highest morbimortality rates. Regarding the age groups, individuals over 50 years old had the highest morbidity rates, while patients over 80 years old had the highest mortality rates, at 23.29%. Finally, the latitude showed a negative correlation, meaning that lower latitudes presented higher rates of morbidity and mortality from skin cancer.</div></div><div><h3>Study limitations</h3><div>Self-reporting of skin color by participants, which may not fully correspond to phototypes. Data was analyzed exclusively from hospitalizations through the Unified Health System (SUS) and severe cases of the disease, as this study focused on hospitalizations and mortality, considering that the main treatment for skin cancer is carried out on an outpatient basis.</div></div><div><h3>Conclusions</h3><div>The majority of Brazilian states showed rising morbimortality rates during the period, with the white-skinned population being the most affected. Additionally, a negative correlation with latitude was observed.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 283-292"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}