Anais brasileiros de dermatologia最新文献

{"title":"Evaluation of dermoscopic findings in patients with cutaneous squamous cell carcinoma according to histopathological subtype and lesion morphology","authors":"Mustafa Ürün ,&nbsp;Yıldız Gürsel Ürün ,&nbsp;Ömer Faruk Elmas ,&nbsp;Nuray Can","doi":"10.1016/j.abd.2024.09.005","DOIUrl":"10.1016/j.abd.2024.09.005","url":null,"abstract":"<div><h3>Background</h3><div>Cutaneous squamous cell carcinoma (cSCC) includes in situ cSCC (Bowen's disease [BD]) and invasive cSCC. By contrast, keratoacanthoma (KA) is a well-differentiated cSCC with self-resolving tendencies. Dermoscopy aids in monitoring vascular and keratin pattern changes to diagnose and track cSCC invasion.</div></div><div><h3>Objectives</h3><div>To examine dermoscopic findings of cSCC according to histopathological differentiation and clinical morphological characteristics.</div></div><div><h3>Methods</h3><div>Clinical and dermoscopic images of 118 cSCCs were retrospectively examined.</div></div><div><h3>Results</h3><div>Compared to other cSCC subtypes, BD more frequently presented with pigmentation (p = 0.028) and a clustered (p = 0.042) or serpiginous (p = 0.006) vascular arrangement. Central keratin plugs were more common in well-differentiated invasive cSCCs (p = 0.021), while white circles surrounding follicles (p &lt; 0.001), ulceration/bleeding (p = 0.001), and red background (p = 0.004) were observed more in poorly differentiated invasive cSCCs. Central keratin plugs (87.5%) and branched vascular arrangements (75%) were observed in patients with nodular KA, with both statistically more frequent than in invasive cSCC (p &lt; 0.001, p = 0.040, respectively). White halos surrounding vessels (p = 0.004) and a clustered vessel arrangement (p = 0.037) were more common in nodular invasive cSCC compared to nodular KA.</div></div><div><h3>Study limitations</h3><div>The number of examined lesions in the subgroups was relatively small.</div></div><div><h3>Conclusions</h3><div>Dermoscopy aids in distinguishing well-differentiated invasive cSCC from poorly differentiated invasive cSCC, distinguishing nodular KA from nodular invasive cSCC, and diagnosing BD. Further studies are needed to identify dermoscopic findings that can distinguish moderately differentiated invasive cSCC from other invasive cSCCs.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 4","pages":"Article 101091"},"PeriodicalIF":3.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paradoxical psoriasiform alopecia secondary to secukinumab: a case report","authors":"Inés Segovia Rodríguez ,&nbsp;María Castillo Gutiérrez ,&nbsp;Fernando Pinedo-Moraleda ,&nbsp;Beatriz Aranegui Arteaga","doi":"10.1016/j.abd.2025.501155","DOIUrl":"10.1016/j.abd.2025.501155","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 4","pages":"Article 501155"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"White piedra: fungal extracellular matrix formation and its importance in pathogenesis. An ultrastructural study","authors":"Hiram Larangeira de Almeida Jr. ,&nbsp;Thales de Moura Assis ,&nbsp;Eduardo Camargo Faria ,&nbsp;Viviane Mazo Fávero Gimenes","doi":"10.1016/j.abd.2025.501140","DOIUrl":"10.1016/j.abd.2025.501140","url":null,"abstract":"<div><h3>Background</h3><div>White piedra is a disease caused by some species of the genus <em>Trichosporon</em>. A case of white piedra was investigated, whose molecular examination identified <em>Cutaneotrichosporon</em> (<em>Trichosporon) debeurmannianum</em> as the causative agent.</div></div><div><h3>Methods</h3><div>Scanning electron microscopy (SEM) was used to examine the affected hairs, as well as the fungal colony of <em>C. debeurmannianum</em> obtained from the hairs. For comparative purposes, a colony of <em>Trichosporon mucoides</em> obtained from a mycotheque was also examined.</div></div><div><h3>Results</h3><div>Examination of the affected hairs using SEM easily demonstrates nodules on the hair shaft with a predominance of rounded yeast-like structures, adhered to each other by a cementing substance. Examination of the <em>C. debeurmannianum</em> colony demonstrates significant adhesion between the fungal cells by a reticular extracellular matrix. Examination of the <em>T. mucoides</em> colony obtained from a mycotheque demonstrates a small production of fibrillar substance between the blastoconidia.</div></div><div><h3>Discussion</h3><div>Examination of the colony obtained from the piedra showed significant formation of extracellular matrix, adhering to and covering the fungal structures, forming a biofilm. This matrix must correspond to the cementing substance described in the condition.</div></div><div><h3>Conclusion</h3><div>The synthesis of the extracellular matrix must be crucial in the formation of white piedra nodules.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 4","pages":"Article 501140"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144534503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adult T-cell lymphoma/leukemia following infective dermatitis in an adult with HTLV-1 infection: a case report","authors":"Denis Miyashiro ,&nbsp;Tatiane Assone ,&nbsp;Augusto César Penalva de Oliveira ,&nbsp;Sabri Saeed Mohammed Ahmed Al-Sanabani ,&nbsp;José Antonio Sanches ,&nbsp;Jorge Casseb","doi":"10.1016/j.abd.2025.501151","DOIUrl":"10.1016/j.abd.2025.501151","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 4","pages":"Article 501151"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pruritus in atopic dermatitis: a cross-sectional study of adult patients from a tertiary university hospital in São Paulo, Brazil","authors":"Georgia Biazus Soares ,&nbsp;Raquel Leão Orfali ,&nbsp;Beatriz Lacerda Averbach ,&nbsp;Qai Ven Yap ,&nbsp;Gil Yosipovitch ,&nbsp;Valeria Aoki","doi":"10.1016/j.abd.2024.09.006","DOIUrl":"10.1016/j.abd.2024.09.006","url":null,"abstract":"<div><h3>Background</h3><div>Chronic pruritus is the defining symptom of atopic dermatitis (AD). Although AD is common in Latin America, there is little data regarding pruritus intensity, characteristics, and effects on quality of life in this population.</div></div><div><h3>Objective</h3><div>This cross-sectional study aimed to evaluate pruritus in 91 patients with AD at a tertiary university hospital in São Paulo, Brazil. Patients aged 14‒65-years old were included in this study.</div></div><div><h3>Methods</h3><div>Patients completed the Itch Questionnaire, the ItchyQoL, and the POEM questionnaires and were asked to rate their itch severity using a 10-point peak pruritus Numerical Rating Scale (NRS). AD severity was assessed via the EASI and the vIGA-AD.</div></div><div><h3>Results</h3><div>The mean age was 29.68 ± 12.87years, and 56.0% of patients were White. 97.8% of patients were currently experiencing pruritus with an average NRS of 7.32 ± 2.22. Patients had associated bleeding (71.4%), heat sensation (63.7%), and pain (54.9%). Worsening factors included stress (93.4%), dry skin (91.2%), and sweat (75.8%). The mean total ItchyQoL score was 78.93 ± 17.20. Female gender was significantly associated with a higher total ItchyQoL score (p = 0.009). Pruritus on the neck, foot, and whole body was associated with higher total ItchyQoL scores in adjusted models (p &lt; 0.05). The EASI, vIGA-AD, and POEM were moderately correlated with itch intensity (<em>r</em> = 0.434, 0.406, and 0.610) and total ItchyQoL score (<em>r</em> = 0.425, 0.436, and 0.631).</div></div><div><h3>Study limitations</h3><div>The predominantly White population cohort may not be representative of the diverse AD phenotypes in the Brazilian patient population. Children under the age of 14 and adults over the age of 65 were excluded from the population cohort. Furthermore, patients included in the study may suffer from other non-dermatological diseases that cause itch, which may influence the outcomes oberserved.</div></div><div><h3>Conclusions</h3><div>Patients with AD in Brazil experience significant pruritus that impacts their quality of life. Gender, body location of itch, associated pain, and stress should all be taken into consideration when evaluating AD patients with pruritus.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 4","pages":"Article 101093"},"PeriodicalIF":3.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143612758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Botryomycosis: series of cases diagnosed between 2000 and 2023 in the Dermatology division of a tertiary hospital","authors":"Nicole de Souza Aranha,&nbsp;João Avancini,&nbsp;Caroline Heleno Chagas de Carvalho,&nbsp;Walter Belda Júnior,&nbsp;Marcello Menta Simonsen Nico","doi":"10.1016/j.abd.2025.501144","DOIUrl":"10.1016/j.abd.2025.501144","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 4","pages":"Article 501144"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144571071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycoplasma-Induced Rash and Mucositis (MIRM) mimicking herpetic stomatitis","authors":"Sara Becerril-Andrés ,&nbsp;Adolfo Alejandro Cabanillas-Cabral ,&nbsp;Gloria Baeza-Hernández","doi":"10.1016/j.abd.2025.501138","DOIUrl":"10.1016/j.abd.2025.501138","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 4","pages":"Article 501138"},"PeriodicalIF":2.6,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translation, cultural adaptation and validation of the Brazilian version of the Alopecia Areata Quality of Life Index (AA-QLI-BRA)","authors":"Paula Rosa Coutinho Goulart Borges Mariottoni ,&nbsp;Leonardo Spagnol Abraham ,&nbsp;Daniel Fernandes Melo ,&nbsp;Rodrigo Pirmez ,&nbsp;Leopoldo Duailibe Nogueira Santos ,&nbsp;Paulo Müller Ramos ,&nbsp;Hélio Amante Miot","doi":"10.1016/j.abd.2025.501146","DOIUrl":"10.1016/j.abd.2025.501146","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 4","pages":"Article 501146"},"PeriodicalIF":2.6,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oxcarbazepine induced systemic lupus erythematosus: a clinical challenge","authors":"Eduardo López Vera ,&nbsp;Elisabeth Gómez Moyano ,&nbsp;María Ayala Blanca ,&nbsp;María Salas Cassinello","doi":"10.1016/j.abd.2025.501154","DOIUrl":"10.1016/j.abd.2025.501154","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 4","pages":"Article 501154"},"PeriodicalIF":2.6,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stabilization of a recalcitrant and aggressive necrobiotic xanthogranuloma with tofacitinib","authors":"Miguel Mansilla-Polo ,&nbsp;Carlos Abril-Pérez ,&nbsp;Daniel Martín-Torregrosa ,&nbsp;Rafael Botella-Estrada","doi":"10.1016/j.abd.2025.501159","DOIUrl":"10.1016/j.abd.2025.501159","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 4","pages":"Article 501159"},"PeriodicalIF":2.6,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}