Ida Duarte , Rosana Lazzarini , Mariana Haffner , Julia P. Silva
{"title":"Interference of the positioning of nickel, chromium and cobalt in the results of patch tests","authors":"Ida Duarte , Rosana Lazzarini , Mariana Haffner , Julia P. Silva","doi":"10.1016/j.abd.2024.03.016","DOIUrl":"10.1016/j.abd.2024.03.016","url":null,"abstract":"<div><h3>Background</h3><div>The positioning of substances, which are co-sensitizers and/or with a tendency to cross-react, is not considered in the technique when applying patch tests (PT).</div></div><div><h3>Objective</h3><div>To investigate the interference of the positioning of nickel (Ni), chromium (Cr) and cobalt (Co) in patch tests (PT) results, when applied close or distant from each other.</div></div><div><h3>Methods</h3><div>PT were performed in patients suspected of allergic contact dermatitis (ACD), using the standard battery (SB), with substances showing a tendency towards cross-react and co-sensitizers applied far apart, and an additional battery (AB) with the metals placed close to each other. For tabulation purposes, only the 96-h reading was considered.</div></div><div><h3>Results</h3><div>Of the 86 tested patients, 33 (38%) had negative testing for metals and 53 (62%) had one or more positive (+) tests for Ni, Cr and/or Co. Concordant results in both tests (SB/ AB) occurred in 18/53 (34%) and 35/53 (66%) had discordant results. Regarding the SB, of the 159 tests with metals (53 patients, three metals), 57 tests were (+) and 102 (-). In the AB, 87 tests were (+) and 72 (-), a statistically significant difference (p < 0.05). Of the 57 (+) tests in the SB, 35 were for Ni, 18 for Co and four for Cr. In AB the number of (+) tests was 87, with 45 (+) tests for Ni, 35 for Co and seven for Cr. The difference in the number of positive tests between the two batteries was statistically significant for Co and Ni.</div></div><div><h3>Study limitations</h3><div>The number of cases.</div></div><div><h3>Conclusion</h3><div>The results showed that the positioning of the metals interferes with the PT results and should be considered as part of the PT application technique.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 272-276"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142811936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John Verrinder Veasey , Bruna Cavaleiro de Macedo Souza , Guilherme Camargo Julio Valinoto
{"title":"Dapsone-induced methemoglobinemia in a child with leprosy","authors":"John Verrinder Veasey , Bruna Cavaleiro de Macedo Souza , Guilherme Camargo Julio Valinoto","doi":"10.1016/j.abd.2024.05.006","DOIUrl":"10.1016/j.abd.2024.05.006","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 391-394"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Silmara Navarro Pennini , Jorge Augusto de Oliveira Guerra , Paula Frassinetti Bessa Rebello , Marília Rosa Abtibol-Bernardino , Amanda Canto Duarte , Higor Marques de Queiroz , Anette Chrusciak-Talhari , Maria das Graças Vale Barbosa Guerra , Sinésio Talhari
{"title":"Telemedicine (mobile-Health) as an alternative in the follow-up of patients in a randomized clinical trial for the treatment of cutaneous leishmaniasis in the state of Amazonas, Brazil","authors":"Silmara Navarro Pennini , Jorge Augusto de Oliveira Guerra , Paula Frassinetti Bessa Rebello , Marília Rosa Abtibol-Bernardino , Amanda Canto Duarte , Higor Marques de Queiroz , Anette Chrusciak-Talhari , Maria das Graças Vale Barbosa Guerra , Sinésio Talhari","doi":"10.1016/j.abd.2024.08.003","DOIUrl":"10.1016/j.abd.2024.08.003","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 355-357"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cytokines, chemokines and growth factors involved in keloids pathogenesis","authors":"Mengguo Liu","doi":"10.1016/j.abd.2024.01.010","DOIUrl":"10.1016/j.abd.2024.01.010","url":null,"abstract":"<div><div>Keloid is a common fibrotic disease, which is difficult to treat. It often causes itching and pain, which greatly disturbs patients in their work and daily life and causing difficulties in social interaction. Its pathogenesis is not clear, but may be related to several aspects: genetic susceptibility, environmental, immunological and endocrine factors, trauma and tension. The central point of its pathogenesis is the excessive proliferation of fibroblasts, with excessive synthesis and secretion of extracellular matrix such as collagen. However, the cause of fibroblast excessive proliferation and differentiation is not clear. Immune abnormalities may play an important role, with cytokines, chemokines, growth factors, and other important immune molecules acting on fibroblasts. This paper presents a detailed and comprehensive literature review on this subject.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 300-307"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of the efficacy of treatment with clobetasol propionate or bexarotene in early-stage mycosis fungoides","authors":"Aslı Aksu Çerman, Pinar Ozdemir Cetinkaya, Birgül Özkesici Kurt, Artun Kırker, İlknur Altunay","doi":"10.1016/j.abd.2024.04.011","DOIUrl":"10.1016/j.abd.2024.04.011","url":null,"abstract":"<div><h3>Background</h3><div>There are few studies in the literature comparing the effectiveness of topical treatments in early-stage mycosis fungoides (MF).</div></div><div><h3>Objectives</h3><div>It was aimed to evaluate the clinical efficacy, side effects and topical treatment compliance with bexarotene or clobetasol propionate in early-stage MF.</div></div><div><h3>Methods</h3><div>A total of 40 patients with stage IA-IB MF were enrolled in the study. Twenty patients were treated with 1% bexarotene gel and 20 patients were treated with 0.05% clobetasol propionate ointment.</div></div><div><h3>Results</h3><div>In the bexarotene group, 11 patients (55%) had complete clinical response (CCR) and 5 patients (25%) had partial response (PR) while in the clobetasol propionate group, 10 patients (50%) had CCR and 9 patients (45%) had PR. The median duration of remission was 10.5 months in the bexarotene group and 4 months in the clobetasol propionate group. The remission period was statistically significantly longer in the bexarotene group (p = 0.032). Irritation symptoms were statistically significantly more common in the bexarotene group (p = 0.001).</div></div><div><h3>Study limitations</h3><div>The limitation of the study was its retrospective design.</div></div><div><h3>Conclusion</h3><div>Both topical bexarotene and topical clobetasol propionate were found to be effective in MF. Irritation symptoms were more common with topical bexarotene. Moreover, the remission period with topical bexarotene was significantly longer.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 237-242"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felipe Bochnia Cerci , Letícia Mari Tashima , Stephanie Matthews , Stanislav N. Tolkachjov
{"title":"Features associated with the use of single or combined reconstructions: analysis of 1,124 Mohs surgeries","authors":"Felipe Bochnia Cerci , Letícia Mari Tashima , Stephanie Matthews , Stanislav N. Tolkachjov","doi":"10.1016/j.abd.2024.07.009","DOIUrl":"10.1016/j.abd.2024.07.009","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 342-345"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Florence Robinson , Lucy Webber , Emma Ormerod , Daniel Keith
{"title":"An extremely prolonged case of drug reaction with eosinophilia and systemic symptoms (DRESS Syndrome) secondary to a penicillin-based antibiotic","authors":"Florence Robinson , Lucy Webber , Emma Ormerod , Daniel Keith","doi":"10.1016/j.abd.2024.07.007","DOIUrl":"10.1016/j.abd.2024.07.007","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 358-359"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ying Li , Yunmei Dong , Xin Zeng , Wei Li , Yu Zhou , Xiaoguang Li
{"title":"The first case of paraneoplastic pemphigus positive for IgG autoantibodies against integrin α6","authors":"Ying Li , Yunmei Dong , Xin Zeng , Wei Li , Yu Zhou , Xiaoguang Li","doi":"10.1016/j.abd.2024.04.016","DOIUrl":"10.1016/j.abd.2024.04.016","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 2","pages":"Pages 380-383"},"PeriodicalIF":2.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}