Anais brasileiros de dermatologia最新文献_第6页

Immunohistochemical analysis of MMP-1 and 2 in patients with lichen planopilaris and frontal fibrosing alopecia 扁平苔藓和额部纤维化性脱发患者MMP-1和2的免疫组化分析。

IF 3.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2026-05-01 Epub Date: 2026-05-19 DOI: 10.1016/j.abd.2026.501359

Renata Indelicato Zac , Emily Ferreira Salles Pilar , Julio Cesar Moraes , Isabel Cristina Gomes Moura , Moisés Salgado Pedrosa , Adilson da Costa

引用次数: 0

Remission of refractory lichen amyloidosis with baricitinib 巴西替尼缓解难治性地衣淀粉样变性

IF 3.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2026-05-01 Epub Date: 2026-05-09 DOI: 10.1016/j.abd.2026.501363

Thiago Lenoir da Silva , Gleison Vieira Duarte

引用次数: 0

Eosinophilic annular erythema in a patient with hepatitis B-related cirrhosis 乙型肝炎相关肝硬化患者嗜酸性环状红斑1例。

IF 3.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2026-05-01 Epub Date: 2026-05-06 DOI: 10.1016/j.abd.2026.501362

Beatriz F. Vilela, Maria Cristina Fialho, Ana Ferreirinha, Cândida Fernandes

引用次数: 0

Psoriasis in skin of color: clinical presentation, diagnostic challenges, and therapeutic considerations 有色皮肤牛皮癣：临床表现、诊断挑战和治疗考虑。

IF 3.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2026-05-01 Epub Date: 2026-05-18 DOI: 10.1016/j.abd.2026.501365

Anderson Costa , Ricardo Romiti

{"title":"Psoriasis in skin of color: clinical presentation, diagnostic challenges, and therapeutic considerations","authors":"Anderson Costa , Ricardo Romiti","doi":"10.1016/j.abd.2026.501365","DOIUrl":"10.1016/j.abd.2026.501365","url":null,"abstract":"<div><div>Psoriasis in individuals with Skin of Color (SOC) shows distinctive clinical features and particularities that require careful consideration for accurate recognition and care. Erythema is often less apparent, and plaques may appear violaceous or dark brown. These features, together with limited discussion of these nuances in textbooks and articles, contribute to delayed diagnosis, greater reliance on skin biopsy, and reduced diagnostic accuracy. Although overall prevalence may be lower than in White populations, SOC patients frequently present with greater body-surface involvement, thicker scale, and a disproportionate impact on quality of life. Early, effective control is critical not only to limit systemic comorbidities and quality of life impairment but also to prevent post-inflammatory dyspigmentation, which can persist for years after clinical resolution and substantially affect psychosocial well-being. Despite major advances in psoriasis research, important gaps remain regarding genetic drivers, immunopathogenesis, and the comparative effectiveness and safety of therapies across diverse populations, gaps compounded by the persistent underrepresentation of SOC in clinical trials. This review synthesizes current evidence on epidemiology, clinical presentation, diagnostic pitfalls, pigmentary sequelae, psychosocial dimensions, and therapeutic options so as to support equitable, patient-centred outcomes for SOC patients living with psoriasis.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 3","pages":"Article 501365"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147969755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Voriconazole-induced lentiginosis in a child: a phototoxicity warning sign 伏立康唑致儿童黄体病：光毒性警告标志

IF 3.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2026-05-01 Epub Date: 2026-05-02 DOI: 10.1016/j.abd.2026.501355

Felipe Henríquez , Vicente Orellana-Westermeyer , Amany Chaaban , Paula Muñoz , Camila Downey , María Teresa Dossi

引用次数: 0

DAPSA scores reflect both articular and cutaneous involvement in psoriatic arthritis DAPSA评分反映银屑病关节炎的关节和皮肤受累。

IF 3.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2026-05-01 Epub Date: 2026-05-18 DOI: 10.1016/j.abd.2026.501368

Qianzi Liu , Minjia Tan , Yehong Kuang

{"title":"DAPSA scores reflect both articular and cutaneous involvement in psoriatic arthritis","authors":"Qianzi Liu , Minjia Tan , Yehong Kuang","doi":"10.1016/j.abd.2026.501368","DOIUrl":"10.1016/j.abd.2026.501368","url":null,"abstract":"<div><h3>Background</h3><div>The Disease Activity Index for Psoriatic Arthritis (DAPSA) is a widely used tool to assess joint involvement in Psoriatic Arthritis (PsA), but its ability to reflect skin disease severity remains unclear.</div></div><div><h3>Objective</h3><div>This study aimed to investigate the association between DAPSA scores and skin disease severity in patients with PsA.</div></div><div><h3>Methods</h3><div>This single-center, cross-sectional study included PsA patients meeting the CASPAR classification criteria at Xiangya Hospital from April 2019 to February 2025. Skin disease severity was assessed using the Psoriasis Area and Severity Index (PASI) and Dermatology Life Quality Index (DLQI), while disease activity was assessed with the DAPSA. Propensity Score Matching (PSM) was applied to adjust for musculoskeletal disease activity.</div></div><div><h3>Results</h3><div>Among the 646 PsA patients (median age 46.0 years; 41.0% male), DAPSA scores increased from 12.6 (SD = 13.2) in patients with no skin disease (PASI = 0) to 20.4 (SD = 16.9) in those with severe skin disease (PASI > 10). Patient global assessment, patient pain assessment scores and C-reactive protein levels also rose with PASI severity (all p < 0.001). After PSM, patients with PASI ≥ 10 had significantly higher DAPSA scores than those with PASI < 10 (25.4 vs. 16.9, p < 0.001). A weak but statistically significant positive correlation was observed between DAPSA and PASI scores (Spearman's rho = 0.256, p = 0.003).</div></div><div><h3>Study limitations</h3><div>Cross-sectional design, single-center setting and potential residual confounding limit causal inference and generalizability.</div></div><div><h3>Conclusion</h3><div>Although not designed to assess skin disease, DAPSA may partially capture skin-related burden through its inflammatory and patient-reported components. In the absence of dedicated skin assessments, DAPSA could serve as a practical and holistic tool for initial disease activity evaluation in PsA.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 3","pages":"Article 501368"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147969787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A progressive sclerotic depigmenting congenital melanocytic nevus in a Chinese patient 先天性黑素细胞痣进行性硬化脱色1例。

IF 3.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2026-05-01 Epub Date: 2026-04-28 DOI: 10.1016/j.abd.2026.501341

Yufan Chen , Yuqing Wang , Juanmei Cao , Tianqi Zhao , Jing Yang , Changzheng Huang

引用次数: 0

Incidence and mortality of cutaneous melanoma stratified by sex, age, and age group – An analysis of the Brazilian population from 2013 to 2023 皮肤黑色素瘤的发病率和死亡率按性别、年龄和年龄组分层——2013年至2023年巴西人口分析

IF 3.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2026-05-01 Epub Date: 2026-04-29 DOI: 10.1016/j.abd.2026.501338

Débora Terra Cardial , Francisco Macedo Paschoal , Luiz Vinicius de Alcantara Sousa

{"title":"Incidence and mortality of cutaneous melanoma stratified by sex, age, and age group – An analysis of the Brazilian population from 2013 to 2023","authors":"Débora Terra Cardial , Francisco Macedo Paschoal , Luiz Vinicius de Alcantara Sousa","doi":"10.1016/j.abd.2026.501338","DOIUrl":"10.1016/j.abd.2026.501338","url":null,"abstract":"<div><h3>Background</h3><div>Cutaneous melanoma remains the leading cause of skin cancer-related mortality worldwide. Despite national awareness campaigns launched by the Brazilian Society of Dermatology since 1999, morbidity and mortality in Brazil remain substantially high.</div></div><div><h3>Methods</h3><div>We conducted an ecological study using secondary data from DATASUS (Hospital Information System – SIH/SUS, Mortality Information System – SIM/SUS, and population estimates from IBGE). Melanoma cases were identified using ICD-10 code C43 between 2013 and 2023. Incidence rates were calculated per 100,000 inhabitants.</div></div><div><h3>Results</h3><div>A total of 20,087 melanoma cases were reported during the study period. Men accounted for 57.5% of cases, a proportion that remained stable throughout the decade. Annual case counts increased from 1,547 in 2013 to 2,047 in 2023, representing a 32% rise. The South and Southeast regions — historically shaped by European immigration and concentrating the majority of White individuals — reported the highest incidence and mortality, consistent with prior population-based cohort data from southern Brazil.</div></div><div><h3>Conclusions</h3><div>These findings highlight a multifactorial scenario in which demographic, behavioral, biological, and structural healthcare determinants converge to shape melanoma burden in Brazil. Sex-specific behavioral factors (lower photo protection adherence, delayed dermatological evaluation among men) and biological differences may contribute to male predominance. Expanding access to early-detection strategies and equitable resource allocation remains essential in a country marked by vast territorial, climatic, and socioeconomic heterogeneity.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"101 3","pages":"Article 501338"},"PeriodicalIF":3.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147799432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Indeterminate cell histiocytosis with ETV3::NCOA2 fusion detected by optical genome mapping 光学基因组定位检测ETV3::NCOA2融合的不确定细胞组织细胞增生。

IF 3.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2026-05-01 Epub Date: 2026-04-28 DOI: 10.1016/j.abd.2026.501342

Miguel Mansilla-Polo , Rafael Andreu-Lapiedra , Irene Luna-del Valle , Esperanza Such-Taboada , Montserrat Évole-Buselli

引用次数: 0

Certolizumab pegol ınduced paradoxical psoriatic alopecia with therapeutic response to bimekizumab Certolizumab pegol ınduced对比美珠单抗治疗反应的矛盾型银屑病脱发。

IF 3.6 4区医学

Anais brasileiros de dermatologia Pub Date : 2026-03-01 Epub Date: 2026-03-26 DOI: 10.1016/j.abd.2026.501320

Gamze Taş Aygar , Furkan Keleş , Feyzanur Elif Biber , Unsal Han , Selda Pelin Kartal

引用次数: 0