Pediatric neuroscience最新文献

Dandy-Walker syndrome: experience at the Hospital for Sick Children, Toronto. 丹迪-沃克综合症:在多伦多病童医院的经历。

Pediatric neuroscience Pub Date : 1989-01-01 DOI: 10.1159/000120445

A Asai, H J Hoffman, E B Hendrick, R P Humphreys

{"title":"Dandy-Walker syndrome: experience at the Hospital for Sick Children, Toronto.","authors":"A Asai, H J Hoffman, E B Hendrick, R P Humphreys","doi":"10.1159/000120445","DOIUrl":"https://doi.org/10.1159/000120445","url":null,"abstract":"Thirty-five patients with the Dandy-Walker syndrome (DWS) treated over the years 1964-1987 at the Hospital for Sick Children, Toronto, were reviewed. Thirty-three patients (94%) had hydrocephalus at the time of diagnosis. The primary association of aqueduct stenosis was excluded by radiological investigation and clinical course in all patients. Associated central nervous system (CNS) anomalies were present in 10 patients. Seven had occipital encephalocele and in 1 of these there was an associated Klippel-Feil syndrome. Four patients had agenesis of the corpus callosum and 1 patient had polyporencephaly. The treatment of these patients has changed over the years in our institution so that during an earlier period, 3 patients were treated by resection of the cyst membranes. We then went through a period of shunting the lateral ventricle so that 21 patients were treated with either a lateral ventricle to peritoneal or lateral ventricle to atrial shunt. More recently, patients with the DWS have been treated with a cyst-peritoneal shunt and 10 patients were thus treated. Only 1 patient was treated with a simultaneous lateral ventricle and cyst-peritoneal shunt. Nine of the twenty-one patients (43%) with a primary lateral ventricle to peritoneum or lateral ventricle to atrial shunt developed a secondary aqueduct stenosis and an isolated fourth ventricle which required additional cyst-peritoneal shunting. Only 1 of the 10 patients treated with a primary cyst-peritoneal shunt required an additional lateral ventricle peritoneal shunt. Two patients initially treated with a lateral ventricle peritoneal shunt and with a primary cyst-peritoneal shunt subsequently had a percutaneous stereotactic third ventriculostomy.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":77766,"journal":{"name":"Pediatric neuroscience","volume":"15 2","pages":"66-73"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000120445","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13776665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 74

Dandy-Walker cyst upward herniation: the role of magnetic resonance imaging and double shunts. Dandy-Walker囊肿向上突出:磁共振成像和双分流术的作用。

Pediatric neuroscience Pub Date : 1989-01-01 DOI: 10.1159/000120446

P Pillay, G H Barnett, C Lanzeiri, R Cruse

引用次数: 21

Ependymomas in two sisters and a maternal male cousin with mosaicism with monosomy 22 in tumour. 室管膜瘤的两个姐妹和一个母系的男性表兄与镶嵌与22单体肿瘤。

Pediatric neuroscience Pub Date : 1989-01-01 DOI: 10.1159/000120447

M L Savard, D M Gilchrist

引用次数: 14

Neuropathology of pediatric liver transplantation. 小儿肝移植的神经病理学。

Pediatric neuroscience Pub Date : 1989-01-01 DOI: 10.1159/000120482

W A Hall, A J Martinez

{"title":"Neuropathology of pediatric liver transplantation.","authors":"W A Hall, A J Martinez","doi":"10.1159/000120482","DOIUrl":"https://doi.org/10.1159/000120482","url":null,"abstract":"We reviewed the clinical histories and autopsy records of 35 pediatric patients (ranging in age from 9 months to 18 years) who underwent orthotopic liver transplantation using ciclosporin and corticosteroids for immunosuppression. At the time of death, 19 children (54%) had encephalopathy, 16 (46%) were lethargic or in coma, 10 (29%) had seizures, and 10 were normal. Neuropathological lesions were found on postmortem examination in all 35 patients. Vascular lesions such as infarction, ischemia, thrombosis, and hemorrhage were the most common neuropathological findings (86%) followed by infectious processes (29%). Candida albicans (2 patients) and Aspergillus fumigatus (3 patients) were the only offending organisms identified, both causing meningoencephalitis. Alzheimer type II astrocytes, a characteristic feature of chronic liver disease, were the single most common autopsy finding (69%). Central pontine myelinolysis was seen in 3 children and basilar artery thrombosis affected 1 child. Neurological complications and their subsequent neuropathology are a significant cause of morbidity and mortality after pediatric liver transplantation. Vascular insults, electrolyte abnormalities, and infections that involve the central nervous system are directly related to liver function and the immunosuppression necessary to maintain graft viability. Only with continued observation after surgery combined with rapid medical and surgical treatment can we hope to improve the prognosis following liver transplantation in the pediatric population.","PeriodicalId":77766,"journal":{"name":"Pediatric neuroscience","volume":"15 6","pages":"269-75"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000120482","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13634379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

Spinal extradural arachnoid cyst. 脊髓硬膜外蛛网膜囊肿。

Pediatric neuroscience Pub Date : 1989-01-01 DOI: 10.1159/000120438

M T Stechison, E B Hendrick, E Cohen

引用次数: 13

Eight-year-old girl with psychomotor retardation and seizures. 八岁女孩，患有精神运动迟缓和癫痫。

Pediatric neuroscience Pub Date : 1989-01-01 DOI: 10.1159/000120469

V Jay, G Ronen, S H Tucker

引用次数: 2

Spinal cord injury without radiographic abnormality in children. 无影像学异常的儿童脊髓损伤。

Pediatric neuroscience Pub Date : 1989-01-01 DOI: 10.1159/000120464

R K Osenbach, A H Menezes