Chiari II型畸形的原因:一个统一的理论。

Pediatric neuroscience Pub Date : 1989-01-01 DOI:10.1159/000120432

D G McLone, P A Knepper

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引用次数: 424

摘要

先天性脊髓脊膜膨出儿童的Chiari II型后脑畸形的原因可以通过胚胎心室系统缺乏扩张来解释。有缺陷的闭塞和开放的神经管阻止了液体和压力在颅小泡内的积聚。这种膨胀对正常的大脑发育至关重要。后窝小、脑组织紊乱和lückenschädel就是结果。

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The cause of Chiari II malformation: a unified theory.

The cause of the Chiari II hindbrain deformity in children born with a myelomeningocele can be explained by the lack of distention of the embryonic ventricular system. Defective occlusion and an open neural tube precludes the accumulation of fluid and pressure within the cranial vesicles. This distention is critical to normal brain development. The small posterior fossa, cerebral disorganization, and lückenschädel are the result.

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Pediatric neuroscience

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