Acta radiologica. Oncology最新文献

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Strontium retention in mouse foetuses at different intervals after contamination of the dam. 坝污染后不同时间内小鼠胎儿体内锶潴留。
Acta radiologica. Oncology Pub Date : 1986-03-01 DOI: 10.3109/02841868609136395
C Rönnbäck
{"title":"Strontium retention in mouse foetuses at different intervals after contamination of the dam.","authors":"C Rönnbäck","doi":"10.3109/02841868609136395","DOIUrl":"https://doi.org/10.3109/02841868609136395","url":null,"abstract":"<p><p>Pregnant CBA mice were intravenously contaminated with radiostrontium (85Sr) on either the 14th, 16th or 18th day post coitum. The radiostrontium content in the foetuses and corresponding placentas as well as that in the femurs of the mothers was measured separately and individually on the 19th day post coitum, i.e. after intervals of 5, 3 and 1 day, respectively. The retained amount of strontium in the foetuses successively increased by the time of contamination, i.e. the later during pregnancy the contamination occurred. Expressed as per cent of the injected amount of 85Sr, the figures ranged from 4.6 per cent in foetuses contaminated on the 18th day to 0.7 per cent for those contaminated already on the 14th day after coitus, with a significantly negative correlation between time and retained amount of radiostrontium. The amount of strontium in the femurs of the mothers was reduced within the same intervals, due partly to decalcification of the skeleton of the mother during the latest part of the pregnancy.</p>","PeriodicalId":77655,"journal":{"name":"Acta radiologica. Oncology","volume":"25 2","pages":"155-9"},"PeriodicalIF":0.0,"publicationDate":"1986-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841868609136395","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14145985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Stereotactic radiation therapy of intracranial lesions. Methodologic aspects. 立体定向放射治疗颅内病变。方法学方面。
Acta radiologica. Oncology Pub Date : 1986-03-01 DOI: 10.3109/02841868609136383
T Greitz, I Lax, M Bergström, J Arndt, B M Berggren, H Blomgren, J Boëthius, M Lindqvist, T Ribbe, L Steiner
{"title":"Stereotactic radiation therapy of intracranial lesions. Methodologic aspects.","authors":"T Greitz,&nbsp;I Lax,&nbsp;M Bergström,&nbsp;J Arndt,&nbsp;B M Berggren,&nbsp;H Blomgren,&nbsp;J Boëthius,&nbsp;M Lindqvist,&nbsp;T Ribbe,&nbsp;L Steiner","doi":"10.3109/02841868609136383","DOIUrl":"https://doi.org/10.3109/02841868609136383","url":null,"abstract":"<p><p>A technique for stereotactic radiation therapy of cerebral tumours and arteriovenous malformations using a linear accelerator (6 MV photons) is proposed. Treatment relies on a fixation system that permits a precise use of the coordinates estimated at stereotactic angiography or stereotactic computed tomography. The field of treatment can be exactly outlined in the CT images during repeat examinations, thus facilitating the recognition of changes induced by radiation. The system also allows the extent of the arteriovenous malformation, as seen at angiography, to be accurately traced in the CT sections thus enabling evaluation of possible radiation damage to surrounding brain structures. The precision of the method as well as its hypothetical merits and disadvantages are discussed. The number of patients treated is still small and the follow-up time is too short in the majority of cases to allow definite conclusions. Examples of preliminary results are given.</p>","PeriodicalId":77655,"journal":{"name":"Acta radiologica. Oncology","volume":"25 2","pages":"81-9"},"PeriodicalIF":0.0,"publicationDate":"1986-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841868609136383","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14145986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 52
Value of hydroxyproline measurements in the assessment of late radiation enteropathy. 羟脯氨酸测定在评价晚期放射性肠病中的价值。
Acta radiologica. Oncology Pub Date : 1986-03-01 DOI: 10.3109/02841868609136392
M Hauer Jensen, T Sauer, K Sletten, J B Reitan, K Nygaard
{"title":"Value of hydroxyproline measurements in the assessment of late radiation enteropathy.","authors":"M Hauer Jensen,&nbsp;T Sauer,&nbsp;K Sletten,&nbsp;J B Reitan,&nbsp;K Nygaard","doi":"10.3109/02841868609136392","DOIUrl":"https://doi.org/10.3109/02841868609136392","url":null,"abstract":"<p><p>In female Wistar rats roentgen irradiation of a 10 cm long temporarily exteriorized mid small intestinal segment was performed. Hydroxyproline, proline, aspartic acid and threonine were measured in intestinal samples 2 to 44 weeks after single or fractionated irradiation, and compared with a histopathologic radiation injury score in order to determine their value as assays of late radiation enteropathy. Two to 4 weeks after irradiation there was good correlation between the histopathologic injury score and the content of hydroxyproline. During the late observation period, there was no difference in hydroxyproline concentration between irradiated and sham-irradiated animals. There was no difference in hydroxyproline concentration in samples from the 1, 2 or 3 fractions groups, although the relative amount of non-collagen protein seemed to increase with fractionation. Determination of the hydroxyproline concentration may be used as an assay of early radiation injury, but it seems to be less suitable for late radiation enteropathy assessment.</p>","PeriodicalId":77655,"journal":{"name":"Acta radiologica. Oncology","volume":"25 2","pages":"137-42"},"PeriodicalIF":0.0,"publicationDate":"1986-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841868609136392","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14145475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Early stage carcinoma of the uterine cervix. Effects of intracavitary radium treatment on lymphoid cells in blood and pelvic lymph nodes. 早期子宫颈癌。腔内镭治疗对血液及盆腔淋巴结淋巴样细胞的影响。
Acta radiologica. Oncology Pub Date : 1986-03-01 DOI: 10.3109/02841868609136390
M Onsrud, I Grahm, G Gaudernack
{"title":"Early stage carcinoma of the uterine cervix. Effects of intracavitary radium treatment on lymphoid cells in blood and pelvic lymph nodes.","authors":"M Onsrud,&nbsp;I Grahm,&nbsp;G Gaudernack","doi":"10.3109/02841868609136390","DOIUrl":"https://doi.org/10.3109/02841868609136390","url":null,"abstract":"<p><p>Sixteen patients with early stage carcinoma of the uterine cervix treated with primary radical hysterectomy and pelvic lymphadenectomy were compared with 17 patients who four to six weeks before the operation received intracavitary treatment with radium. The calculated radiation dose to the pelvic wall was approximately 10 Gy. The distribution of lymphoid cells in blood and pelvic lymph nodes was studied by an indirect immunofluorescence technique using monoclonal antibodies. The radium treated group showed a significant reduction of circulating OKT4+ (T helper) and OKT8+ (T suppressor/cytotoxic) lymphocytes. The number of Leu7+ (natural killer) cells and 1D5+ cells (monocytes) was not changed, but the ratio between monocytes and T cells was increased after radium therapy. In cell suspensions obtained from the pelvic lymph nodes, the radium treatment induced a significant reduction of the OKT4+ cell fraction. It is concluded that this low dose rate regimen of intracavitary treatment induces changes in the immune system which are of the same type as those seen after external field irradiation.</p>","PeriodicalId":77655,"journal":{"name":"Acta radiologica. Oncology","volume":"25 2","pages":"127-30"},"PeriodicalIF":0.0,"publicationDate":"1986-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841868609136390","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14145473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Treatment of non-Hodgkin lymphomas in the nasal cavities and paranasal sinuses. A failure analysis. 鼻腔及鼻窦非霍奇金淋巴瘤的治疗。故障分析。
Acta radiologica. Oncology Pub Date : 1986-03-01 DOI: 10.3109/02841868609136384
M Kondo, A Mikata, Y Inuyama, M Uematsu, N Shigematsu, I Nishiguchi, S Hashimoto
{"title":"Treatment of non-Hodgkin lymphomas in the nasal cavities and paranasal sinuses. A failure analysis.","authors":"M Kondo,&nbsp;A Mikata,&nbsp;Y Inuyama,&nbsp;M Uematsu,&nbsp;N Shigematsu,&nbsp;I Nishiguchi,&nbsp;S Hashimoto","doi":"10.3109/02841868609136384","DOIUrl":"https://doi.org/10.3109/02841868609136384","url":null,"abstract":"Twenty-five patients with sinonasal lymphoma were treated mainly with irradiation. All were non-Hodgkin lymphomas of diffuse type. Twenty patients had stage IA, 2 had stage IB, 1 stage IIA, 1 stage IIIA, and 1 stage IVA disease. Relapse developed in 16 (64%) of the 25 patients, with a failure rate of 64 per cent in the stage I patients (14/22). Most patients with failures had distant spread of the disease with or without local recurrence. Only one patient had local recurrence alone at the first relapse. Histologic classification according to the new working formulation seemed to be a reliable prognostic indicator for relapse: failure rates for low, intermediate, and high grade lymphomas were 0 per cent (0/2), 46 per cent (6/13), and 100 per cent (10/10), respectively. Computed tomography was valuable for planning of radiation therapy and for follow-up.","PeriodicalId":77655,"journal":{"name":"Acta radiologica. Oncology","volume":"25 2","pages":"91-7"},"PeriodicalIF":0.0,"publicationDate":"1986-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841868609136384","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14145989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Therapy of esophageal carcinoma. Results from the Joint Group on Esophageal Carcinoma in Rotterdam. 食管癌的治疗。鹿特丹食管癌联合治疗组的结果。
Acta radiologica. Oncology Pub Date : 1986-03-01 DOI: 10.3109/02841868609136388
J G van Andel, J Dees, W M Eijkenboom, H van Houten, J J Jobsen, H J Mud, H Obertop, W L van Putten, M van Blankenstein, M Eeftinck Schattenkerk
{"title":"Therapy of esophageal carcinoma. Results from the Joint Group on Esophageal Carcinoma in Rotterdam.","authors":"J G van Andel,&nbsp;J Dees,&nbsp;W M Eijkenboom,&nbsp;H van Houten,&nbsp;J J Jobsen,&nbsp;H J Mud,&nbsp;H Obertop,&nbsp;W L van Putten,&nbsp;M van Blankenstein,&nbsp;M Eeftinck Schattenkerk","doi":"10.3109/02841868609136388","DOIUrl":"https://doi.org/10.3109/02841868609136388","url":null,"abstract":"<p><p>During the period 1978-1981 172 patients were referred to the Rotterdam Joint Group on Esophageal Carcinoma. Ninety-one patients were considered for combined therapy, comprising radiation therapy and surgery, and 10 patients refused surgery. The figures given in this material are actuarial survival values corrected for intercurrent death (the actuarial overall survival in parentheses). The 4-year survival in 69 patients who completed this treatment was 39 per cent (26%) (significantly better for women compared with men; significantly better for tumors less than 2 vertebrae compared with tumors greater than or equal to 2 vertebrae). The resectability rate was 85 per cent and the operation mortality rate 20 per cent. Thirty-eight patients had curative radiation therapy with a 4-year corrected survival of 5 per cent (3%). For palliative treatment, radiation therapy and endoscopic introduction of a Celestin tube were mostly used. The results of curative as well as of palliative treatment of esophageal carcinoma have shown improvement during the past decade compared with an earlier period.</p>","PeriodicalId":77655,"journal":{"name":"Acta radiologica. Oncology","volume":"25 2","pages":"115-20"},"PeriodicalIF":0.0,"publicationDate":"1986-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841868609136388","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13571598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Radiographic evaluation of pulmonary fibrosis following mantle field irradiation in Hodgkin's disease. 霍奇金病套野照射后肺纤维化的影像学评价。
Acta radiologica. Oncology Pub Date : 1986-03-01 DOI: 10.3109/02841868609136387
B V Jensen, N L Carlsen, K Peters, N I Nissen, P G Sørensen, S Walbom-Jørgensen
{"title":"Radiographic evaluation of pulmonary fibrosis following mantle field irradiation in Hodgkin's disease.","authors":"B V Jensen,&nbsp;N L Carlsen,&nbsp;K Peters,&nbsp;N I Nissen,&nbsp;P G Sørensen,&nbsp;S Walbom-Jørgensen","doi":"10.3109/02841868609136387","DOIUrl":"https://doi.org/10.3109/02841868609136387","url":null,"abstract":"<p><p>Sixty-nine patients given mantle field radiation therapy for Hodgkin's disease and considered relapse-free and possibly cured were re-examined for pulmonary fibrosis as observed on antero-posterior and lateral chest radiographs. A method is described for the systematic evaluation of these late stage changes, which are observed following irradiation, in a numerical form. The method gave reproducible results in this series, the correlation coefficient being 0.72/0.81 and 0.73 respectively for the intra-observer and the inter-observer variations. The method thus may facilitate comparison between different patient materials.</p>","PeriodicalId":77655,"journal":{"name":"Acta radiologica. Oncology","volume":"25 2","pages":"109-13"},"PeriodicalIF":0.0,"publicationDate":"1986-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841868609136387","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14145471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Geographic variations of breast carcinoma incidence in Sweden. Are the differences real? 瑞典乳腺癌发病率的地理差异。这些差异是真实的吗?
Acta radiologica. Oncology Pub Date : 1986-03-01 DOI: 10.3109/02841868609136385
L E Rutqvist, J Carstensen, B Mattsson, G Mårdsjö
{"title":"Geographic variations of breast carcinoma incidence in Sweden. Are the differences real?","authors":"L E Rutqvist,&nbsp;J Carstensen,&nbsp;B Mattsson,&nbsp;G Mårdsjö","doi":"10.3109/02841868609136385","DOIUrl":"https://doi.org/10.3109/02841868609136385","url":null,"abstract":"<p><p>The validity of the reported geographic variations of breast carcinoma incidence in Sweden was assessed by examination of two possible sources of bias: non-notification to the Cancer Registry of diagnosed carcinoma cases and 'biologically benign' breast carcinoma, i.e. with a low disease-specific lethality, e.g. detected accidentally at autopsy. No significant geographic differences in registration deficit were found even though non-notification tended to be slightly higher for old patients in low-incidence areas. Autopsy cases were estimated to account for less than one per cent of all cases and tended to be more frequent in high-incidence areas but the regional differences were generally small and not significant. An analysis of the relationship between 10-year relative survival and age-standardized incidence in 27 different regions revealed no significant correlation, whereas there was a significant positive correlation between age-standardized incidence and mortality. These findings indicate that non-lethal breast carcinoma cases do not explain the variations of incidence. In conclusion, no evidence was found suggesting that the geographic differences were artifactual. Registration deficit and autopsy cases, however, may have slightly increased the variations among elderly women.</p>","PeriodicalId":77655,"journal":{"name":"Acta radiologica. Oncology","volume":"25 2","pages":"99-104"},"PeriodicalIF":0.0,"publicationDate":"1986-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841868609136385","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14145879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Cytogenetic damage induced in human lymphocytes by low doses of 60Co gamma rays delivered at high and low dose rates. 低剂量高剂量率和低剂量率60Co γ射线对人淋巴细胞的细胞遗传学损伤。
Acta radiologica. Oncology Pub Date : 1986-03-01 DOI: 10.3109/02841868609136393
L Fabry
{"title":"Cytogenetic damage induced in human lymphocytes by low doses of 60Co gamma rays delivered at high and low dose rates.","authors":"L Fabry","doi":"10.3109/02841868609136393","DOIUrl":"https://doi.org/10.3109/02841868609136393","url":null,"abstract":"<p><p>Chromosomal aberrations were investigated in human peripheral blood lymphocytes after exposure to low doses of 60Co gamma rays delivered acutely or at low dose rates (0.1 or 0.03 Gy/h). Chromosome analysis was performed in cells collected after a 44 to 46 hour culture time in order to avoid scoring of second division cells, and the dose-related induction of aberrations was analysed by the maximum likelihood method. In all cases, the induction of dicentrics was well described by a linear-quadratic dose response model (Y = aD + bD2), the data obtained at a low dose rate being equally well fitted to a linear equation. According to earlier findings on the mechanisms of aberration formation, the two lesions originating from single ionizing tracks have to be produced within a period of approximately 5 hours, in order to interact and to give rise to dicentric aberrations, which could explain the decrease in the quadratic term at the low dose rate since the highest doses were delivered over a period of more than 5 hours.</p>","PeriodicalId":77655,"journal":{"name":"Acta radiologica. Oncology","volume":"25 2","pages":"143-6"},"PeriodicalIF":0.0,"publicationDate":"1986-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841868609136393","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14145982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Evaluation of the pulse wash sampling technique for screening of uterine cervical carcinoma. 脉冲冲洗取样技术对宫颈癌筛查的评价。
Acta radiologica. Oncology Pub Date : 1986-03-01 DOI: 10.3109/02841868609136391
I Näslund, G Auer, F Pettersson, K Sjövall
{"title":"Evaluation of the pulse wash sampling technique for screening of uterine cervical carcinoma.","authors":"I Näslund,&nbsp;G Auer,&nbsp;F Pettersson,&nbsp;K Sjövall","doi":"10.3109/02841868609136391","DOIUrl":"https://doi.org/10.3109/02841868609136391","url":null,"abstract":"<p><p>The efficacy of a new sampling technique performed for early detection of cervical carcinoma is compared with Pap smears with the swab-and-wooden spatula technique in 312 women. In this new method, sampling of cytologic material is achieved by using a pulse wash instrument described in a previous article. Cells are rinsed and detached by liquid jets of 0.2 mm in diameter which are produced by a spray nozzle connected with a pressure hose to a high pressure pump. The liquid molecules pass through the spray nozzle at a speed of 20 m/s thus creating a successful rinsing effect on cervical epithelium due to high kinetic energy. Rinsed cells are mixed with the small amount of the flushing liquid. The suspension of cells and liquid accumulated in the speculum is then transported to a small container by a suction pump. The results of this work suggest that the pulse wash technique gives a more representative cell sample than the Pap smear sampling technique, thus offering a simple method to decrease false negative diagnoses in the detection of carcinoma of the uterine cervix. Samples by the new technique give an abundance of cells for slide preparation for cytodiagnostic techniques as well as for additional cytochemical, immunocytochemical and microbiologic diagnostic techniques.</p>","PeriodicalId":77655,"journal":{"name":"Acta radiologica. Oncology","volume":"25 2","pages":"131-6"},"PeriodicalIF":0.0,"publicationDate":"1986-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/02841868609136391","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14145474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
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