{"title":"STATUS GIZI PADA ANAK YANG MENDERITA DEMAM TIFOID","authors":"Intan Nur ‘Ain, Harapan Parlindungan Ringoringo, Nurul Hidayah, Roselina Panghiyangani, Rahmiati Rahmiati","doi":"10.20527/ht.v6i1.8793","DOIUrl":"https://doi.org/10.20527/ht.v6i1.8793","url":null,"abstract":"Bakteri Salmonella typhi menyebabkan demam tifoid, infeksi usus kecil yang parah. Usia, jenis kelamin, dan status gizi adalah tiga faktor yang sering diidentifikasi pada pasien demam tifoid yang masih anak-anak atau remaja. Pemeriksaan status gizi ini diambil menggunakan pengukuran antropometri. Riset ini bertujuan untuk menganalisis gambaran status gizi pada anak yang menderita demam tifoid di RSD Idaman Banjarbaru periode Oktober 2020-September 2022. Populasi riset ini sebanyak 51 pasien anak yaitu 25 balita dan 26 anak usia 5-18 tahun. Data yang digunakan ialah data sekunder dari RSD Idaman Banjarbaru. Hasil riset ini menunjukkan status gizi anak yang menderita demam tifoid berdasarkan usia mayoritas dialami pada usia 5-18 tahun sebanyak 26 anak (51%), berdasarkan jenis kelamin dialami oleh anak laki-laki sebanyak 32 anak (62.7%), berdasarkan BB/U pada balita dengan gizi buruk sebanyak 11 anak (44%), berdasarkan PB/U atau TB/U pada balita dengan gizi buruk sebanyak 15 balita (60%), berdasarkan BB/PB atau BB/TB pada balita dengan buruk sebanyak 8 balita (32%), dan berdasarkan IMT/U pada anak dengan gizi buruk sebanyak 18 anak (35.3%). Kesimpulan dari riset ini anak yang menderita demam tifoid memiliki status gizi baik.","PeriodicalId":77544,"journal":{"name":"Homeostasis in health and disease : international journal devoted to integrative brain functions and homeostatic systems","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79787636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karo Karo Gabriel Pranata, Hariadi Yuseran, Alfi Yasmina, Ferry Armanza, M. Mashuri
{"title":"PERBEDAAN KADAR MCV DAN MCHC PADA PASIEN KANKER SERVIKS DENGAN PERDARAHAN DAN TANPA PERDARAHAN","authors":"Karo Karo Gabriel Pranata, Hariadi Yuseran, Alfi Yasmina, Ferry Armanza, M. Mashuri","doi":"10.20527/ht.v6i1.8804","DOIUrl":"https://doi.org/10.20527/ht.v6i1.8804","url":null,"abstract":": Perdarahan sering terjadi pada pasien dengan kanker serviks, dan dapat menimbulkan anemia. Tipe anemia yang diderita bisa ditentukan dengan parameter Mean Corpuscular Volume (MCV) dan Mean Corpuscular Hemoglobin Concentration (MCHC). Penelitian ini bertujuan untuk mengetahui perbedaan kadar MCV dan MCHC pada pasien kanker serviks dengan perdarahan dan tanpa perdarahan. Desain penelitian ini adalah cross-sectional. Subjek penelitian adalah pasien kanker serviks di RSUD Ulin Banjarmasin periode April sampai Agustus 2021 yang sesuai dengan kriteria inklusi dan eksklusi. Variabel bebasnya adalah perdarahan dan variabel terikatnya adalah kadar MCV dan MCHC. Analisis dilakukan dengan uji T tidak berpasangan dan uji Mann-Whitney. Diperoleh 45 orang pasien kanker serviks, dan hasil penelitian menunjukkan bahwa 58% mengalami perdarahan. Rerata kadar MCV pada pasien dengan dan tanpa perdarahan adalah 73,74±7,64 fl dan 81,26±4,98 fl (p < 0,001), dan rerata kadar MCHC pada pasien dengan dan tanpa perdarahan adalah 30,89±1,45 g/dl dan 32,41±1,47 g/dl (p < 0,001). Dapat disimpulkan bahwa terdapat perbedaan kadar MCV dan MCHC pada pasien kanker serviks dengan perdarahan dan tanpa perdarahan.","PeriodicalId":77544,"journal":{"name":"Homeostasis in health and disease : international journal devoted to integrative brain functions and homeostatic systems","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86994600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Yosephine Himawan, Eko Suhartono, Fujiati Fujiati, M. Mashuri, B. Setiawan
{"title":"STUDI IN SILICO: PREDIKSI DAMPAK KOBALT DAN MERKURI TERHADAP PROTEIN PADA KEJADIAN DIABETES MELITUS","authors":"Maria Yosephine Himawan, Eko Suhartono, Fujiati Fujiati, M. Mashuri, B. Setiawan","doi":"10.20527/ht.v6i1.8801","DOIUrl":"https://doi.org/10.20527/ht.v6i1.8801","url":null,"abstract":"Kalimantan Selatan merupakan provinsi yang memiliki sumber daya alam yang melimpah khususnya di sektor pertambangan. Logam berat hasil buangan tambang batubara yang tidak diolah bersifat sangat beracun bagi lingkungan dan manusia seperti merkuri dan kobalt yang berdampak pada kesehatan manusia seperti gangguan proses glikolisis. Penelitian in bertujuan untuk mengetahui interaksi logam berat merkuri dan kobalt terhadap enzim glukokinase, 11β-hydroxysteroid dehydrogenase-1, dipeptidyl peptidase-IV, dan Interleukin-1β dengan PDB ID: 1V4S, 2BEL, 1J2E, 9ILB yang diambil dari protein data bank serta menggukan website molecular docking MIB2: Metal Ion Binding Site Prediction and Docking server. Hasil docking divisualisasikan menggunakan aplikasi Chimera versi 1.16. Ditemukan hasil dari molecular docking logam berat merkuri dan kobalt dapat berinteraksi dengan keempat protein. Ion logam merkuri berikatan secara hidrofobik dengan residu asam amino interleukin 1 β dan ikatan kovalen koordinasi glukokinase, 11β-hydroxysteroid dehydrogenase-1, dan dipeptidyl peptidase-IV. Sedangkan ion logam kobalt berikatan secara kovalen koordinasi dengan residu asam amino enzim glukokinase, 11β-hydroxysteroid dehydrogenase-1, dipeptidyl peptidase-IV, dan Interleukin-1β. Dari keempat protein, ion logam merkuri berikatan paling kuat dengan enzim dipeptidyl peptidase-IV dikarenakan dipeptidyl peptidase-IV memiliki binding potensial yang lebih kuat tetapi pada jarak ikatan ion merkuri lebih mendekati ke enzim glukokinase tersebut.","PeriodicalId":77544,"journal":{"name":"Homeostasis in health and disease : international journal devoted to integrative brain functions and homeostatic systems","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83838278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EFEKTIVITAS EKSTRAK ETANOL DAUN SIRIH MERAH (Piper crocatum Ruiz & Pav.) SEBAGAI REPELEN TERHADAP NYAMUK Aedes aegypti","authors":"Mayang Rustia Anggraini Putri, Erida Wydiamala, Lisda Hayatie","doi":"10.20527/ht.v5i3.7736","DOIUrl":"https://doi.org/10.20527/ht.v5i3.7736","url":null,"abstract":"Dengue Hemorrhagic Fever (DHF) is a disease caused by the dengue virus and transmitted through the bite of the Aedes aegypti mosquito. One effective option to prevent the transmission of the disease is by avoiding the bite of the Aedes aegypti mosquito by using a repellent-type insecticide. The use of chemical insecticides widely circulated in the market often has negative effects, such as irritation to the skin. Red betel leaf contains several active compounds that may act as contact poisons and are effective as repellents. The purpose of this study was to test the effectiveness of ethanol extract of red betel leaf against Aedes aegypti mosquitoes. This study was an true experimental post-test only with a control group design, consisting of 4 concentrations of ethanolic extract of red betel leaf (12.5%, 25%, 50%, 100%), DEET 15% K(+), and aquades K(-) with four replications. Serial concentrations ethanol extract of red betel leaf K(+), and K(-) were applied to the back skin of mice exposed to mosquitoes for 5 minutes for every minute. The concentration of 100% at every minute had no significant difference with the positive control (p>0.05). The conclusions from this research were red betel leaf ethanol extract with concentrations of 12.5%, 25%, 50%, and 100% was effective as a mosquito repellent Aedes aegypti, and red betel leaf ethanol extract with a concentration of 100% was equivalent to 15% DEET","PeriodicalId":77544,"journal":{"name":"Homeostasis in health and disease : international journal devoted to integrative brain functions and homeostatic systems","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77680697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Azra Inan Abdillah, Triawanti Triawanti, Azma Rosida, Meitria Syahadatina Noor, Noor Muthmainah
{"title":"PENGARUH PENYULUHAN TERHADAP PENGETAHUAN DAN SIKAP MENGONSUMSI TABLET TAMBAH DARAH","authors":"Muhammad Azra Inan Abdillah, Triawanti Triawanti, Azma Rosida, Meitria Syahadatina Noor, Noor Muthmainah","doi":"10.20527/ht.v5i3.7739","DOIUrl":"https://doi.org/10.20527/ht.v5i3.7739","url":null,"abstract":"Iron supplementation tablets (TTD) are dietary supplements containing iron that can be given to adolescent girls to prevent iron deficiency anemia (ADB). Although the administration of TTD in adolescent girls has been implemented, the lack of knowledge and unsupportive attitude toward consuming TTD in adolescent girls can reduce the effectiveness on preventing ADB. This study aims to determine the effect of health education on knowledge and attitude of consuming TTD, a review of adolescent girls at SMP Negeri 25 Banjarmasin. Quasi-experimental research method with one-group pretest-posttest design. The research subjects were 30 people with random sampling technique. Data collection techniques using knowledge and attitude questionnaires. The analysis using the Wilcoxon Signed Ranks test showed that there was a significant difference between knowledge (p=0.00) and attitude (p=0.019) before and after health education for adolescent girls. In conclusion, health education can increase the knowledge and attitude of consuming TTD in adolescent girls","PeriodicalId":77544,"journal":{"name":"Homeostasis in health and disease : international journal devoted to integrative brain functions and homeostatic systems","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80026217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PERBANDINGAN AKTIVITAS ANTIBAKTERI EKSTRAK DAUN SUNGKAI DAN DAUN TANJUNG TERHADAP Salmonella typhi IN VITRO","authors":"Emilia Zulaiha, Noor Muthmainah, Agung Biworo","doi":"10.20527/ht.v5i3.7721","DOIUrl":"https://doi.org/10.20527/ht.v5i3.7721","url":null,"abstract":"Sungkai and Tanjung plants are often used by the community as traditional medicine. Extracts of sungkai leaf and tanjung leaf extract are known to contain active compounds that act as antibacterials such as alkaloids, flavonoids, saponins, tannins and others. This study aimed to analyze the comparison of the antibacterial activity of sungkai and tanjung leaf extracts against Salmonella typhi in vitro. This study was a true experimental study using the Posttest-Only With Control Group Design method with the treatment groups in the form of sungkai leaf extract and tanjung leaf extract with each test concentration of 25%, 50%, 75% and 100% and chloramphenicol 30μg as a positive control and aquadest as a negative control. Data were analyzed using One-Way ANOVA test, Post-hoc LSD and independent T-test. The results of the average diameter of the inhibition zone formed from concentrations of 25%, 50%, 75% and 100% of sungkai leaf extract on the growth of Salmonella typhi were 6.45 mm, 9.20 mm, 11.95 mm, 13.08 mm, respectively. and tanjung leaf extract of 12.70 mm, 15.42 mm, 17.46 mm, 19.20 mm. Based on the results of One-Way ANOVA statistical analysis, the value (p<0.05). The conclusion of this study was that there was a significant difference in the antibacterial activity of the extracts of sungkai and tanjung leaves against Salmonella typhi ","PeriodicalId":77544,"journal":{"name":"Homeostasis in health and disease : international journal devoted to integrative brain functions and homeostatic systems","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75970928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gita Shabella, Harapan Parlindungan Ringoringo, Meitria Syahadatina Noor
{"title":"MANIFESTASI KLINIS DAN PROFIL HEMATOLOGI BALITA DENGAN DIARE AKUT DI RSD IDAMAN BANJARBARU TAHUN 2020-2021","authors":"Gita Shabella, Harapan Parlindungan Ringoringo, Meitria Syahadatina Noor","doi":"10.20527/ht.v5i3.7723","DOIUrl":"https://doi.org/10.20527/ht.v5i3.7723","url":null,"abstract":"Acute diarrhea is an increase in stool discharge with a softer or more liquid consistency than usual, occurring at least 3 times in 24 hours with or without mucus and blood lasting <14 days. The purpose of this study is to find out the clinical manifestations, hematology profile, and examination of feces of children under five at Idaman Banjarbaru Hospital in 2020-2021. The methods used in this study are descriptive retrospective. Data retrieval techniques are done purposive sampling by paying attention to inclusion and exclusion criteria. The study sample included 35 children with clinical manifestation data and a complete hematological profile. The results showed the most age in the group of 12-36 months with a percentage of 60%. By gender there were 21 children (64.86%) male. The study concluded that 27 children (77.14%), were in vomiting in 26 children (74.28%). The majority with normal leukocyte levels with a percentage of 22 (62.85%) children, hemoglobin levels within normal limits are as many as 25 children (71.43%).","PeriodicalId":77544,"journal":{"name":"Homeostasis in health and disease : international journal devoted to integrative brain functions and homeostatic systems","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88219184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PERBEDAAN KADAR HEMOGLOBIN PRATRANSFUSI PADA PASIEN TALASEMIA BETA MAYOR SEBELUM DAN SAAT PANDEMI COVID-19","authors":"Helda Pareang, Harapan Parlindungan Ringoringo, Meitria Syahadatina Noor, Edi Hartoyo, Rahmiati Rahmiati","doi":"10.20527/ht.v5i3.7722","DOIUrl":"https://doi.org/10.20527/ht.v5i3.7722","url":null,"abstract":"Beta thalassemia major is a disorder that occurs due to the absence of beta globin chain production and is characterized by severe clinical symptoms. The purpose of this study was to explain the differences in pretransfusion hemoglobin levels in beta thalassemia major patients before and during the COVID-19 pandemic at Idaman Hospital Banjarbaru in 2019-2020. This research was a descriptive-analytic study with a cross sectional approach. Collecting data through medical records of patients with beta thalassemia major. The sampling technique was total sampling. The sample was 35 patients. The results showed that there were 18 women (51,43%) patients, the most age was in the age range 12 - <18 as many as 12 (34,29%) patients, and underweight nutritional status (BB/TB) were 24 (68,57) patients. Pre-transfusion hemoglobin levels were classified into before and during the COVID-19 pandemic. The average value of pretransfusion hemoglobin levels before the COVID-19 pandemic was 8,95 g/dL and during the COVID-19 pandemic was 8,92 g/dL. The test used was the paired sample test and the results obtained were p = 0,83 because p > 0,05, there was no significant difference between pretransfusion hemoglobin levels before and during the COVID-19 pandemic","PeriodicalId":77544,"journal":{"name":"Homeostasis in health and disease : international journal devoted to integrative brain functions and homeostatic systems","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85162353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nurulhuda Suwandari Ningrum, Mohammad Rudiansyah, D. Pratiwi, Nani Zaitun, Fransiscus Xaverius Hendriyono
{"title":"KORELASI LAMA HEMODIALISIS DAN KADAR C-REACTIVE PROTEIN (CRP) PADA PASIEN HEMODIALISIS RUTIN","authors":"Nurulhuda Suwandari Ningrum, Mohammad Rudiansyah, D. Pratiwi, Nani Zaitun, Fransiscus Xaverius Hendriyono","doi":"10.20527/ht.v5i3.7730","DOIUrl":"https://doi.org/10.20527/ht.v5i3.7730","url":null,"abstract":"Chronic kidney disease (CKD) is structural or functional abnormalities in kidney for more than 3 months so the patient must undergo hemodialysis to assist the kidneys. CKD patients on hemodialysis therapy have persistent inflammation due to their disease. One way to determine inflammation is assess a biomarker in form of c-reactive protein (CRP). This study aims to determine the correlation between hemodialysis duration and CRP levels in routine hemodialysis patients. The research method used is observational analytic with cross-sectional approach. This study involved 100 patients with total of 93 patients who met the inclusion criteria and the sample size were 74 people with total random sampling technique. The results of the study from data that weren’t normally distributed showed the median of hemodialysis duration was 18 months, the median CRP level was 3.25 mg/L, and there was no significant correlation between the hemodialysis duration and CRP levels in routine hemodialysis patients.","PeriodicalId":77544,"journal":{"name":"Homeostasis in health and disease : international journal devoted to integrative brain functions and homeostatic systems","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82103241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nor Hayatun Thaibah, Ferry Armanza, Siti Wasilah, Hariadi Yuseran, Lena Rosida
{"title":"GAMBARAN TATALAKSANA PASIEN PREEKLAMPSIA YANG TERKONFIRMASI COVID-19 DAN NON-COVID-19 DI RSUD ULIN BANJARMASIN","authors":"Nor Hayatun Thaibah, Ferry Armanza, Siti Wasilah, Hariadi Yuseran, Lena Rosida","doi":"10.20527/ht.v5i3.7740","DOIUrl":"https://doi.org/10.20527/ht.v5i3.7740","url":null,"abstract":"Preeclampsia is hypertension in pregnancy which is characterized with blood pressure of 140/90 mmHg after 20 weeks of gestation, accompanied by proteinuria.3. There are three types of drugs that are often used in preeclampsia treatment, they are nifedipine, methyldopa, and MgSO4. This study was aimed to find out the description of confirmed covid-19 and non covid-19 preeclampsia patients treatment at Ulin Hospital, Banjarmasin in the COVID-19 period seen from administration of MgSO4, antihypertensive, method and time of termination. This study applied descriptive method with data collection through medical records. The sampling technique used purposive sampling which was selected based on the criteria. In this study, a sample of 176 preeclampsia patients with confirmed COVID-19 and non-COVID-19 were obtained. However, from the 176 samples, which met the criteria, only 55 preeclampsia patients had confirmed COVID-19 and 80 non-COVID-19 preeclampsia patients. The results showed that all severe preeclampsia patients with confirmed COVID-19 were given MgSO4 with a percentage of 100%.. Antihypertensives were often given was a combination of methyldopa + nifedipine. The most common method of delivery was by cesarean section.","PeriodicalId":77544,"journal":{"name":"Homeostasis in health and disease : international journal devoted to integrative brain functions and homeostatic systems","volume":"200 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72676199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}