Aesthetic Surgery Journal最新文献

{"title":"Evaluating Real-World Use and Adverse Events from 3262 Patients Treated with 18,203 Cycles of Cryolipolysis for Localized Fat Reduction: A Multi-Location Practice Retrospective Chart Review.","authors":"Daniel P Friedmann, Jatin Kommera, Prishita Durga, Amogh Shashidhar, Kritin K Verma","doi":"10.1093/asj/sjaf007","DOIUrl":"https://doi.org/10.1093/asj/sjaf007","url":null,"abstract":"<p><strong>Background: </strong>Cryolipolysis is an established method for noninvasive focal subcutaneous fat reduction.</p><p><strong>Objectives: </strong>To highlight the safety and real-world use of this technology.</p><p><strong>Methods: </strong>Electronic medical records of all patients treated with a commercially available cryolipolysis technology (CoolSculpting and CoolSculpting Elite, Allergan Aesthetics, Irvine, CA) between 01/2016 and to 06/2023 at a multi-location group practice was retrospectively reviewed. Extracted procedure-related data included number of total sessions and cycles, number of sessions and cycles per body area, and treatment-related adverse events. A cycle was defined as 1 applicator treating 1 body area.</p><p><strong>Results: </strong>3262 patients (2797 female, 465 male) treated with 18,203 cycles across 6245 sessions were included. Mean age at first treatment was 45.0±12.8 (15-83) years. Mean number of cycles per patient was 5.6±6.5 (1-177), with a median of 4 cycles per patient. Mean number of sessions per patient was 1.9±1.7 (1-38), with a median of 1 session per patient. The most commonly treated area was the lower abdomen (n=1761, 4734 cycles), and the most frequently treated body area combination was the upper/mid + lower abdomen (n=937, 5140 cycles). Dual submental treatment was more common than single applicator therapy. Eighty-seven patients exhibited 180 adverse events (2.05% of cycles), including 3 body areas (n=2) with paradoxical adipose hyperplasia (PAH).</p><p><strong>Conclusions: </strong>This retrospective chart review of cryolipolysis treatment, among the largest to-date, demonstrates its overall safety and broad use across numerous body areas. PAH risk per cycle is between 0.018% (1 in 5501) and 0.048% (1 in 2063), depending on the calculation method.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nipple Position and Clinical Outcomes Following Nipple-Sparing Mastectomy: An Examination of Prepectoral and Subpectoral Implant-Based Reconstruction Using 3D Imaging.","authors":"Carrie S Stern, Francis D Graziano, Donovan R White, Ronnie L Shammas, Ethan L Plotsker, Elizabeth Smith-Montes, Lillian Boe, Jacob Levy, Tracy-Ann Moo, Virgilio Sacchini, Robert Allen, Babak Mehrara, Jonas A Nelson","doi":"10.1093/asj/sjaf004","DOIUrl":"https://doi.org/10.1093/asj/sjaf004","url":null,"abstract":"<p><strong>Background: </strong>Nipple-sparing mastectomy (NSM) has become increasingly popular in recent years. However, the impact of prepectoral versus subpectoral implant reconstruction on nipple position, clinical outcomes, and patient-reported outcomes (PROs) after NSM remains unknown.</p><p><strong>Objective: </strong>We hypothesized that prepectoral reconstruction would lead to a more anatomic nipple position and improved clinical outcomes and PROs as compared to subpectoral reconstruction following NSM.</p><p><strong>Methods: </strong>Surgical characteristics, complications, and PROs in NSM patients with implant-based reconstruction from 2018 to 2021 were prospectively collected. Nipple displacement from baseline was analyzed using three-dimensional (3D) surface imaging.</p><p><strong>Results: </strong>216 patients underwent 391 NSMs, separated into subpectoral (n = 96) and prepectoral (n = 120) cohorts. There were no differences in demographic and comorbidities between cohorts. Prepectoral showed a greater incidence of short-term return to OR (21% vs 10%, p=0.026). 3D analysis for 96 patients and 175 nipple positions were conducted. Compared to preoperative baseline, 3D imaging at 12 months postoperatively showed that the subpectoral cohort had greater straight-line distance between the nipples (23.1 mm vs 17.3 mm, p<0.001) and more lateral nipple displacement (9.2 mm vs 6.1 mm, p<0.001) as compared to the prepectoral cohort. Regression analysis found no relationship between incision pattern and nipple displacement. No postoperative differences were seen in PROs.</p><p><strong>Conclusions: </strong>Subpectoral NSM reconstruction was found to have more lateralized nipple displacement as compared to prepectoral patients, regardless of incision pattern used. Nipple displacement after NSM can play a significant role in postoperative aesthetic appearance and should be considered when deciding implant plane.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Prospective, Randomized, Controlled Trial of Methylene Blue Injection for Costal Cartilage Harvest Postoperative Analgesia.","authors":"Ziang Zhang, Ziyu Zhu, Hengxin Liu, Jie Chen, Changxin Jin, Xi Zhang","doi":"10.1093/asj/sjae203","DOIUrl":"10.1093/asj/sjae203","url":null,"abstract":"<p><strong>Background: </strong>In plastic surgery, costal cartilage is an excellent support material. However, postoperative pain from costal cartilage harvesting can impact patient recovery and satisfaction with the surgery. Recent reports have shown that methylene blue (MB) is an effective local analgesic in postoperative management.</p><p><strong>Objectives: </strong>We aimed to evaluate the safety and effectiveness of MB for pain relief in patients undergoing costal cartilage harvesting.</p><p><strong>Methods: </strong>A total of 106 patients undergoing costal cartilage harvesting surgery were selected from the plastic surgery department between December 2022 and March 2024. They were randomly divided into 2 groups: the MB group and the ropivacaine group, with 53 patients in each group. Pain levels were assessed with a numerical rating scale, the Insomnia Severity Index (ISI), arm elevation angle, and postoperative satisfaction scales at 1 day, 3 days, 5 days, 1 week, 1 month, and 3 months postoperatively.</p><p><strong>Results: </strong>Patients receiving MB exhibited a significant decrease in pain scores from 5 days to 1 month of treatment compared to the ropivacaine group. Additionally, in the MB group there was an improvement in ISI scores from 5 days to 1 month compared to the ropivacaine group. Furthermore, during the 3-month follow-up, the MB group had significant increases in satisfaction scores compared to the control group. Arm elevation angle in the MB group was significantly higher compared to the ropivacaine group at 5 days, 1week, and 1month. No serious adverse events were reported, with only 2 patients experiencing an allergic rash.</p><p><strong>Conclusions: </strong>Methylene blue demonstrated significant pain reduction with minimal adverse effects.</p><p><strong>Level of evidence: 3 (therapeutic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"NP65-NP70"},"PeriodicalIF":3.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142612573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Permanent Nipple-Areolar Complex Sensitivity Loss Following Reduction Mammaplasty.","authors":"Stephanie Francalancia, Mary Lou, Damon McIntire, Nikhil Sobti, Brooke Barrow, Josué Marquez-Garcia, Daniel Kwan, Rachel Sullivan, Paul Liu, Karl Breuing","doi":"10.1093/asj/sjae215","DOIUrl":"10.1093/asj/sjae215","url":null,"abstract":"<p><strong>Background: </strong>Predictors for permanent nipple-areolar complex (NAC) insensitivity after reduction mammaplasty are sparsely defined.</p><p><strong>Objectives: </strong>We analyzed factors associated with NAC insensitivity over long-term follow-up.</p><p><strong>Methods: </strong>A retrospective analysis of reduction mammaplasties on 1598 breasts performed by 4 surgeons from March 2015 to February 2023 was conducted. Data on patient demographics, intraoperative factors, and postoperative complications were collected from patient records. Analysis was conducted by breast, separated into breasts with NAC insensitivity (permanent and transient) and those without. Wilcoxon rank sum test for continuous variables and Fisher's exact test or Pearson's chi-square test for categorical variables evaluated differences between the groups. Univariate and multivariate logistic regression analyzed the association of pedicle choice with NAC insensitivity onset and permanence.</p><p><strong>Results: </strong>Of 1598 breasts, 9.8% had loss of NAC sensation, of which 49.0% had permanent loss. A total of 51.0% regained sensitivity, taking an average of 116 days (median 64, range 6-798) to regain sensation. NAC-insensitive breasts had longer sternal notch to NAC (P < .001) and NAC to IMF (P < .001) measurements, greater weight removed (P < .001), and fat necrosis co-complication (P = .022). Greater weight removed (P = .044) and longer sternal notch to NAC measurements (P = .011) were associated with permanent insensitivity. The superomedial pedicle was associated with an increased rate of transient NAC insensitivity, whereas the inferior pedicle had a decreased rate. There was no significant association between pedicle choices and permanent insensitivity.</p><p><strong>Conclusions: </strong>Transient loss of NAC sensitivity is associated with pedicle choice, and breasts with permanent insensitivity were more likely to have longer breast measurements and a greater amount of tissue removed.</p><p><strong>Level of evidence: 4 (therapeutic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"NP50-NP56"},"PeriodicalIF":3.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body Contouring Finesse: Dynamic Definition Liposculpture and Bipolar Radiofrequency Microneedling.","authors":"Alfredo E Hoyos, Mauricio E Perez Pachon, Neil M Vranis","doi":"10.1093/asj/sjae152","DOIUrl":"10.1093/asj/sjae152","url":null,"abstract":"<p><p>Dynamic definition liposculpture (HD2) is considered a highly sought after procedure in body sculpting surgery by patients. Radiofrequency microneedling is a cutting edge technology with evidence-based outcomes demonstrating skin tightening and retraction. These ancillary procedures complement and enhance the results of dynamic definition liposculpture. A retrospective review of patient records from 2022 to 2024 was conducted. All patients who underwent high definition (HD) or HD2 in combination with fractional radiofrequency microneedling treatments by the senior author (A.E.H.) were included. Data collected included patient demographics, areas treated, and any complications. A total of 86 patients were included: 16 in 2022, 62 in 2023, and 8 in 2024. The most frequently treated area was the abdomen, followed by the back, face, neck, thighs, and arms. The average age of patients was 40.0 years in 2022, 40.8 years in 2023, and 44.4 years in 2024. The average BMI was 23.9 kg/m2 in 2022, 24.3 kg/m2 in 2023, and 25.2 kg/m2 in 2024. Minimal complications were observed, with some patients requiring further interventions such as scar correction and nevus resection. Avoiding superficial liposuction by relying on radiofrequency microneedling to target the adipose tissue directly beneath the dermis decreases the risk for iatrogenic (cannula related) superficial contour irregularities and makes the overall operation safer and more reliable.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":"45 Supplement_1","pages":"S10-S22"},"PeriodicalIF":3.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11736780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eye-Opening Effect Achieved by Modified Transconjunctival Lower Blepharoplasty.","authors":"Takayuki Kubo","doi":"10.1093/asj/sjae205","DOIUrl":"10.1093/asj/sjae205","url":null,"abstract":"<p><strong>Background: </strong>Enophthalmia (abnormally sunken eyeball in the socket) and ptotic upper lid, as well as lower lid symptoms, are commonly observed in patients seeking periorbital rejuvenation.</p><p><strong>Objectives: </strong>The aim of this study was to assess the effect of transconjunctival lower blepharoplasty (TCLB) modified by adding deframing and decompression maneuvers to the lower orbital fat compartment (LOFC) and its support structures to obtain better results in both the lower and upper lids.</p><p><strong>Methods: </strong>Modified TCLB was performed in patients with lower eyelid symptoms. Palpebral fissure height (PFH) (the distance between the upper and lower eyelids in vertical alignment with the center of the pupil) was measured before surgery and 12 months postoperatively from 3-dimensional photographs. These data were compared to validate the postoperative eye-opening effect. The weight of the excised fat from each LOFC was also measured and compared.</p><p><strong>Results: </strong>Forty patients (36 females and 4 males) who underwent modified TCLB were followed up 12 months postoperatively. Mean [standard deviation] preoperative PFHs were 8.41 [1.15] mm (range, 6.1-10.7 mm) for the right and 8.41 [1.12] mm (range, 5.5-10.4 mm) for the left. Postoperative PFHs were 9.26 [0.95] mm (range, 6.4-11.1 mm) for the right and 9.21 [0.94] mm (range, 6.2-11.1 mm) for the left. The improvement in postoperative eye opening was statistically significant. The total excised LOFC was 0.43 [0.24] g (range, 0-1.2 g) for the right and 0.42 [0.25] g (range, 0-1.5 g) for the left. The largest amount of fat was excised bilaterally from the lateral LOFC, and the difference was statistically significant.</p><p><strong>Conclusions: </strong>The results after the modified TCLB clearly demonstrate increased eye-opening ability and marked resolution of observable symptoms. The anatomical dynamics of the orbit involved in this procedure are detailed through scientific data.</p><p><strong>Level of evidence: 4 (therapeutic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"126-135"},"PeriodicalIF":3.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11852279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-House Virtual Planning and 3D-Printed Surgical Guides for Reconstructive Rhinoplasty.","authors":"Josep Rubio-Palau, Joana Gonçalves, Albert Malet-Contreras, Núria Adell-Gómez, Trini Arenas-Costa, Wenceslao Calonge, Arnau Valls-Esteve, Adaia Valls-Ontañón","doi":"10.1093/asj/sjae179","DOIUrl":"10.1093/asj/sjae179","url":null,"abstract":"<p><strong>Background: </strong>Performing rhinoplasty in patients with craniofacial malformations remains a challenge, even for experienced surgeons. Advances in 3-dimensional technology and their application in surgical planning and printing of cutting guides and splints have become important tools for improving aesthetic and functional results.</p><p><strong>Objectives: </strong>The aim of this preliminary report was to describe an in-house workflow for surgical planning and printing of cutting guides and splints for complex rhinoplasty cases.</p><p><strong>Methods: </strong>An in-house workflow for complex rhinoplasty was described, as applied in the maxillofacial department of a children's hospital specializing in the treatment of cleft and craniofacial malformations.</p><p><strong>Results: </strong>Customized surgical guides helped the surgeon harvest and mold potential septal and costochondral grafts more accurately, reduced surgical time, and verified the dimensions of the sculpted nasal shape following surgical planning templates. Patient satisfaction according to the Rhinoplasty Outcome Evaluation questionnaire was 18/24.</p><p><strong>Conclusions: </strong>The presented workflow represents a potential asset for obtaining more accurate and satisfactory results in complex rhinoplasties.</p><p><strong>Level of evidence: 5 (diagnostic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"136-140"},"PeriodicalIF":3.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142003423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-Breast Implantable Medical Devices and Associated Malignancies: A Systematic Review.","authors":"Natalia Ziolkowski, John Milkovich, Alexandra D'Souza, Ryan E Austin, Patricia McGuire, Frank Lista, Jamil Ahmad","doi":"10.1093/asj/sjae178","DOIUrl":"10.1093/asj/sjae178","url":null,"abstract":"<p><p>Innovation in healthcare has led to the development of numerous implantable medical devices (IMDs). However, advances in our knowledge of breast implant-associated malignancies have raised questions about the prevalence, etiology, and management of malignancies associated with non-breast IMDs. The objective of this study was to examine the prevalence and characteristics of malignancies associated with non-breast IMDs. An expert medical librarian developed the search strategy for this review. Databases included MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials. In addition, gray literature sources were searched, and relevant references from systematic reviews and meta-analyses were included. The PRISMA guideline was followed for the review. Risk of bias was evaluated with the JBI Critical Appraisal tools. A total of 12,230 articles were reviewed, with a total of 77 meeting inclusion criteria. Risk of bias was highest with case reports (moderate, average of 65.1% with range of 37.5% to 100%) and low for the remaining study types. In total, 616 cases of IMD-associated malignancies were identified. Malignancies associated with IMDs were reported in the head and neck (543, 88.1%), lower extremity (57, 9.6%), thorax (9, 1.4%), abdomen (3, 0.5%), and genitourinary system (2, 0.3%). The most common malignancy type in the lower extremity was sarcoma, in the head and neck was squamous cell carcinoma, and in the thorax was lymphoma. This study is the first comprehensive systematic review of its kind. Overall, the oncologic risk of IMDs is low. The discussion of malignancy is an important part of the overall consent process, and malignancy should be considered with any new signs or symptoms in the anatomic area of an implant. More data are needed to better understand how primary malignancies occur around IMDs and how to reduce this risk.</p><p><strong>Level of evidence: 3: </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"148-155"},"PeriodicalIF":3.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141905556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Preoperative Psychological Screening Tool: Piloting the Cosmetic Readiness Questionnaire (Pilot-CRQ).","authors":"Toni D Pikoos, Ben Buchanan, David Hegarty, Susan L Rossell","doi":"10.1093/asj/sjae187","DOIUrl":"10.1093/asj/sjae187","url":null,"abstract":"<p><strong>Background: </strong>Patients with psychological risk factors such as body dysmorphic disorder (BDD) and unmanaged mental health concerns are considered at higher risk for dissatisfaction with aesthetic procedures. Identifying these risks before a procedure may decrease the chance of adverse outcomes for patients and practitioners.</p><p><strong>Objectives: </strong>In this study we aimed to develop a comprehensive psychological screening tool to assess patient's psychological suitability for surgical and nonsurgical aesthetic procedures.</p><p><strong>Methods: </strong>Items for the Pilot Cosmetic Readiness Questionnaire (CRQ) were developed by psychologists (n = 3) and then reviewed by plastic surgeons (n = 2) and nonsurgical cosmetic doctors (n = 3). Patient interviews (n = 15) and piloting of the questionnaire (n = 69) provided data regarding the scale's initial psychometric properties.</p><p><strong>Results: </strong>Results supported the reliability and validity of the Pilot-CRQ's subscales of Body Dysmorphia, Psychological Distress, Self-Criticism, Perfectionism, and Lack of Openness. Lack of Openness was a validity scale that examined the degree that respondents might be underreporting symptoms. The CRQ predicted individuals with a BDD diagnosis, as rated by a blinded expert clinical psychologist, with high sensitivity and specificity.</p><p><strong>Conclusions: </strong>These results provide support for the Pilot-CRQ identifying people with BDD and psychological factors related to aesthetic treatment outcomes and provide a strong basis for employing the CRQ in clinical contexts and in future research.</p><p><strong>Level of evidence: 2 (diagnostic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"202-207"},"PeriodicalIF":3.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Tranexamic Acid Administration During Liposuction on Bleeding Complications and Ecchymosis: A Systematic Review.","authors":"Rawan ElAbd, Yasmina Richa, Panthea Pouramin, Todd Dow, Meshari AlNesef, Tyler Safran, Mirko Gilardino, Osama A Samargandi","doi":"10.1093/asj/sjae193","DOIUrl":"10.1093/asj/sjae193","url":null,"abstract":"<p><p>Liposuction is the most frequently performed cosmetic procedure. Tranexamic acid (TXA) has emerged as a promising blood loss reducing agent in plastic surgery, but its value in liposuction is still being studied. This systematic review investigates the safety and efficacy of TXA in reducing blood loss during liposuction procedures. A systematic review of PubMed, EMBASE, and Cochrane databases from inception to June 2023 was performed. The primary objective was to compare blood loss, hematoma rate, and ecchymosis from liposuction procedures in patients who received TXA with those who did not. The secondary objective was to assess the incidence of TXA-related complications. A total of 9 studies were included, published between 2018 and 2023, of which 8 were prospective and 1 was retrospective. A total of 345 intervention vs 268 control arms were compared. Follow-up time ranged from 1 to 14 days. Mean age and mean BMI ranged from 33 to 50 years and 23 to 30 kg/m2, respectively. Blood loss in aspirate was significantly less with TXA administration as assessed in 5 studies (P < .05). Of the 5 studies that described assessment of the incidence of ecchymosis, all reported less bruising with TXA use. Among all the studies, only 1 reported postoperative complications in 5 patients requiring transfusion in the control group (without TXA). The evidence provided in the literature suggests that TXA administration in liposuction is safe and effective for reducing blood loss and ecchymosis by both intravenous and local administration.</p><p><strong>Level of evidence: 3 (therapeutic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"171-179"},"PeriodicalIF":3.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142143014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}