Aesthetic Surgery Journal最新文献

{"title":"The Relationship Between Glabellar Contraction Patterns and Glabellar Muscle Anatomy: A Magnetic Resonance Imaging-based Study.","authors":"Daniel J Rams, Mateusz Koziej, Jeremy B Green, Brian S Biesman, Elżbieta Szczepanek, Tadeusz J Popiela, Monika Ostrogórska, Agnieszka Gleń, Rod J Rohrich, Michael Alfertshofer, Sebastian Cotofana","doi":"10.1093/asj/sjae202","DOIUrl":"https://doi.org/10.1093/asj/sjae202","url":null,"abstract":"<p><strong>Background: </strong>Glabellar contraction patterns were introduced to the scientific literature to help guide glabellar neuromodulator injection algorithms. However, the relationship between the underlying musculature and its influence on these glabellar contraction patterns is unclear.</p><p><strong>Objectives: </strong>The aim of this study was to identify via Magnetic Resonance Imaging (MRI) glabellar muscle parameters that display an influence on the distribution of individual glabellar contraction patterns.</p><p><strong>Methods: </strong>Thirty-four healthy young individuals of Caucasian Polish descent were investigated (17 women, 17 men) with a mean age of 23.6 years and a mean BMI of 22.8 kg/m2. MRI-based measurements of length, thickness, width and surface area of procerus, corrugator supercilii, orbicularis oculi and frontalis muscles were conducted.</p><p><strong>Results: </strong>Unadjusted models revealed that there was no statistically significant difference between the five glabellar contraction types and the investigated muscle parameters indicating that independent of the skin rhytid pattern, the underlying musculature was not different between the investigated groups in this sample with all p ≥ 0.102. Adjusted models revealed that sex was the most influential factor due to males displayed in general higher values for the investigated parameters when compared to females.</p><p><strong>Conclusions: </strong>The results of this study reveal that based on the MRI parameters investigated and based on the investigated cohort, there does not appear to be a strong relationship between glabellar contraction patterns and underlying glabella muscle anatomy. Utilizing glabellar contraction patterns to design neuromodulator treatment algorithms may be of variable clinical merit.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of Human and Porcine Derived Acellular Dermal Matrices in Prepectoral Breast Reconstruction: A Long-term Clinicaland Histologic Evaluation.","authors":"Allen Gabriel, G Patrick Maxwell, Erin O'Rorke, John R Harper","doi":"10.1093/asj/sjae175","DOIUrl":"https://doi.org/10.1093/asj/sjae175","url":null,"abstract":"<p><strong>Background: </strong>Human acellular dermal matrices (ADMs) remain the most used matrices in prosthetic breast reconstruction. However, the availability and cost of ADMs limit their use in prepectoral reconstruction-which requires large amounts of ADM-and alternative matrices are therefore being explored.</p><p><strong>Objectives: </strong>The aim of this study was to demonstrate the safety and efficacy of human-porcine ADM constructs via clinical outcomes and histologic evidence of graft integration.</p><p><strong>Methods: </strong>Consecutive patients undergoing tissue-expander/implant reconstructions with human-porcine ADM constructs were included. Biopsies of both ADMs were obtained at expander/implant exchange and evaluated for cellularization, vascularization, and inflammation. Postoperative complications were retrieved from patient records.</p><p><strong>Results: </strong>Fifty-nine patients met the inclusion criteria. Mean [standard deviation] follow-up was 6.7 [0.56] years; minimum follow-up was 5 years. Any complication rate was 8.6%, including skin necrosis (6.9%), seroma (1.7%), expander/implant exposure (1.7%), and return to the operating room (2.6%). A total of 138 ADM biopsy specimens were obtained from 38 patients at expander/implant exchange. Histologic analyses revealed lower fibroblast infiltration and vascularization and higher inflammatory response in porcine vs human ADM specimens, consistent with published results in nonhuman primates. Despite these differences, there were no cases of graft rejection, capsular contracture, or expander/implant loss.</p><p><strong>Conclusions: </strong>Porcine ADM performs clinically in a similar manner to human ADM, albeit with minor differences in cellular ingrowth and vascularization, suggesting that it may be an alternative to human ADM in prepectoral breast reconstruction.</p><p><strong>Level of evidence: 3: </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence Analysis of Periorbital Rejuvenation.","authors":"Caroline C Kreh, Laura Roider, Peter K Firouzbakht, Charles Nathan, Christian A Prada, Herflund G Lund, Deniz Sarhaddi, Kevin Chen","doi":"10.1093/asj/sjae201","DOIUrl":"10.1093/asj/sjae201","url":null,"abstract":"<p><strong>Background: </strong>Periorbital rejuvenation surgery aims to restore a youthful appearance to the face. Despite the popularity of these procedures, few objective measurements exist to evaluate their impact on perceived facial aging.</p><p><strong>Objectives: </strong>This study aims to quantify the impact of brow lift and blepharoplasty on age as perceived by convolutional neural network (CNN) algorithms.</p><p><strong>Methods: </strong>A retrospective review was performed on patients who underwent upper blepharoplasty, lower blepharoplasty, and/or brow lift at a single cosmetic practice between 2018 and 2023. Collected data included patient demographics, procedure performed, fat pad resection, and pre- and postoperative frontal images. Each photo was analyzed by four artificial intelligence (AI) platforms to estimate the change in perceived age following surgery. The estimated age reduction was compared between procedures.</p><p><strong>Results: </strong>Of the 153 included patients, 118 underwent blepharoplasty, 12 underwent brow lift, and 23 had both blepharoplasty and brow lift. Across all AI platforms, the mean age estimation percent error was 10.6%, with a tendency for AI to underestimate compared to true age. Univariate analysis revealed an age reduction following any surgery of 1.03 years (p<0.001). When controlling for other variables, brow lift patients saw a mean age reduction of 1.432 years (p=0.031). Upper and lower blepharoplasty, patient characteristics, and ancillary procedures were not found to be independently associated with significant age reduction.</p><p><strong>Conclusions: </strong>Brow lifts provide significant reduction in perceived age. When planning for periorbital rejuvenation, a thorough preoperative evaluation should be performed, and additional consideration should be given to brow lifting procedures.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fat Grafting and Adipose Stem Cells for Facial Systemic Sclerosis: A Systematic Review of the Literature.","authors":"Aurora Almadori, Sze Ching Fung, Christopher P Denton, Peter E M Butler","doi":"10.1093/asj/sjae200","DOIUrl":"https://doi.org/10.1093/asj/sjae200","url":null,"abstract":"<p><strong>Background: </strong>The oro-facial modification occurring in systemic sclerosis are detrimental for patients, but the therapeutic options are limited.</p><p><strong>Objectives: </strong>This systematic review aimed to perform an up-to-date appraisal of the literature focusing on fat grafting and other adipose stem cell-based therapies for the treatment of facial systemic sclerosis, determining its efficacy and safety, and investigating the current practice for treatment optimization.</p><p><strong>Methods: </strong>The review was prospectively registered in PROSPERO (CRD42021286268) and followed the PRISMA principles. Multiple databases were searched and only original studies were included.</p><p><strong>Results: </strong>Over the 12 studies matching the inclusion criteria, 174 patients were treated. Of them, 87.3% (n = 152) were considered to have improved. The complications, graded with the Clavien-Dindo grading system, were grade 1 (no treatment required) or 2 (antibiotic required). Patients received an average of 2.5 ± 3.68, median 1.35 (range 1-14), lipotransfer procedures. Overall, an amount of 14.60 ± 6.24 ml was injected in the overall facial area, median 16 (range 27-3) ml. The average interval between procedures was 5.30 ± 2.04 months, with a median of 6 (range 3-6.91) months. At the time of inclusion, patients were diagnosed with scleroderma disease on an average 14.7 ± 7.35 years.</p><p><strong>Conclusions: </strong>Fat grafting for facial systemic sclerosis is effective and safe. The definitive durability of the effect is still unclear, and the optimal number of treatments must be determined to define a precise evidence-based protocol. The body of evidence is highly fragmented, with disagreement in the surgical technique used and outcome assessment, making results from different studies often not comparable. The level of evidence is overall low or very low, and the risk of bias of published studies is overall medium to high. RCTs are urgently needed.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peripheral Nerve Injury After Deoxycholic Acid (ATX-101) Injection in an Experimental Rat Model.","authors":"David Chi, Sai Pinni, Shea Maloy, Noah Llaneras, Daniel A Hunter, Matthew D Wood, Marissa M Tenenbaum, Susan E Mackinnon","doi":"10.1093/asj/sjae198","DOIUrl":"10.1093/asj/sjae198","url":null,"abstract":"<p><strong>Background: </strong>Deoxycholic acid (ATX-101) is a drug administered by subcutaneous injection for local fat reduction. However, ATX-101 treatment has been reported to cause marginal mandibular nerve injury with noticeable functional deficits when targeting submental fat. As a cytolytic agent with some selectivity for adipocytes, ATX-101 may damage the lipid-rich myelin surrounding peripheral nerves.</p><p><strong>Objectives: </strong>This study seeks to characterize the nerve injection injury from ATX-101 in an experimental rat model.</p><p><strong>Methods: </strong>Using a rat sciatic nerve injection model, intrafascicular and extrafascicular injections of deoxycholic acid (ATX-101) were compared to lidocaine (positive control) and saline (negative control). Nerves were harvested at a 2-week endpoint for histomorphometric analysis.</p><p><strong>Results: </strong>Cross-sectional area of nerve injury was significantly increased by ATX-101 injection at 75±15% with intrafascicular ATX-101 (p<0.001), 41±21% with extrafascicular ATX-101 (p<0.01), and 38±20% with positive control lidocaine (p<0.01) compared to 7±13% with negative control saline. Demyelinating injury was a significant mechanism of injury in the affected nerve fibers compared to uninjured nerve fibers (p<0.04), but there was no difference in axon-to-myelin area ratio between the lidocaine and ATX-101 cohorts. After two weeks, Wallerian degeneration was evident with only small regenerating nerve fibers present in the ATX-101-injured groups compared to saline (2.54±0.26um vs 5.03±0.44um, p<0.001) in average width.</p><p><strong>Conclusions: </strong>Deoxycholic acid (ATX-101) is capable of extensive nerve injury in rats. The mechanism of action for ATX-101 does not preferentially target myelin more than other common neurotoxic agents. Appropriate knowledge of surgical anatomy and injection technique is necessary for any practitioners providing ATX-101 injections.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142306966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Right Analysis for the Right Data in Aesthetic Surgery Research.","authors":"Lucas Gallo, Isabella Churchill, Cameron Levielle, Christopher Coroneos","doi":"10.1093/asj/sjae197","DOIUrl":"https://doi.org/10.1093/asj/sjae197","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142306967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autologous Cryopreserved Adipose Tissue Using an Innovative Technique: An In Vitro Biological Characterization.","authors":"Carlo Ventura, Elena Bondioli, Roy De Vita, Gino Rigotti, Federico Morigi, Francesca Scarpellini, Francesca Di Fede, Alessandro Nanni-Costa, Davide Melandri","doi":"10.1093/asj/sjae192","DOIUrl":"https://doi.org/10.1093/asj/sjae192","url":null,"abstract":"<p><strong>Background: </strong>The use of autologous adipose tissue transplantation in plastic and orthopedic surgery such as breast, reconstructions and intra-articular injection, has become an attractive surgical treatment with satisfactory clinical outcomes. Nevertheless, repeated liposuctions necessary to harvest fatty tissue normally performed with sedation or general anesthesia, may represent a noteworthy concern.</p><p><strong>Objectives: </strong>To demonstrate through an in vivo characterization, the validity of the surgical option to use cryopreserved autologous adipose tissue harvested in a single shot for repeated graft transfer, in breast reconstruction, without impairment of cell viability and sterility.</p><p><strong>Methods: </strong>Adipose tissue is collected as a standard liposuction from patients who need numerous fat grafting procedures for breast reconstruction. According to an innovative and patented cryopreservation method, autologous adipose tissue is subsequently fractioned in a sterile bag system and frozen at RER Tissue Bank of the Emilia Romagna Region. Each graft is evaluated for sterility and cell viability immediately after harvesting and 1, 3, 6, 12 and preliminarily 18 months after cryopreservation and thawing.</p><p><strong>Results: </strong>In vitro results showed that after processing, middle, and long-term cryopreservation and subsequent thawing, autologous cryopreserved adipose tissue, retains absence of bacterial contamination, high cellular viability and unmodified histomorphological properties, thereby ensuring the maintenance of the stromal vascular niche and the filling properties in multi-step different surgical procedures.</p><p><strong>Conclusions: </strong>In vitro study and sterility assessment, showed that autologous cryopreserved adipose tissue grafting is a safe procedure able to avoid multiple liposuction surgery. No impairment of either sterility, cell viability, and morphology were observed over time.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on: The Prevalence and Histological Characteristics of the Double Capsule Phenomenon in Breast Augmentation with Implants.","authors":"Elizabeth J Hall-Findlay","doi":"10.1093/asj/sjae195","DOIUrl":"https://doi.org/10.1093/asj/sjae195","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Importance of Adapting the Surgical Technique to the Characteristics of the Breast Implant Surface Type.","authors":"Nenad Stepic","doi":"10.1093/asj/sjae189","DOIUrl":"https://doi.org/10.1093/asj/sjae189","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":"55 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142257953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aesthetic Plastic Surgery National Databank Statistics 2023.","authors":"","doi":"10.1093/asj/sjae188","DOIUrl":"https://doi.org/10.1093/asj/sjae188","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":"44 Supplement_2","pages":"1-25"},"PeriodicalIF":3.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}