{"title":"Correction: Buccal Fat Suspension: Not Just a Lift-Restoring the Foundational Anatomy of a Youthful Cheek.","authors":"","doi":"10.1093/asj/sjag194","DOIUrl":"https://doi.org/10.1093/asj/sjag194","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148975406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erin N Abbott, Ruoying Li, Daniella King, Paulina E Chumakov, Elianna Dash, Carrie A Kubiak, Stephane A Braun, Allen Gabriel, Megan Vucovich, Lauren M Mioton, Galen Perdikis
{"title":"Short-term Outcomes of Polydioxanone Synthetic Mesh in 2-stage Breast Reconstruction: A Single-Center Comparative Study.","authors":"Erin N Abbott, Ruoying Li, Daniella King, Paulina E Chumakov, Elianna Dash, Carrie A Kubiak, Stephane A Braun, Allen Gabriel, Megan Vucovich, Lauren M Mioton, Galen Perdikis","doi":"10.1093/asj/sjag019","DOIUrl":"10.1093/asj/sjag019","url":null,"abstract":"<p><strong>Background: </strong>Polydioxanone (PDO) mesh offers a more cost-effective option than biologic mesh for soft tissue support for 2-stage breast reconstruction with tissue expansion but differences in complication rates have not been well established.</p><p><strong>Objectives: </strong>The purpose of this study was to present the early postoperative complications recorded by a single center following immediate tissue expander (TE) insertion for breast reconstruction using PDO mesh, biologic mesh, or no mesh.</p><p><strong>Methods: </strong>A retrospective cohort study was performed of patients undergoing immediate TE insertion following mastectomy over a 3-year period (2021-2024) at a single academic center. Patients were grouped by mesh type. Univariate and multivariate regression analyses were performed.</p><p><strong>Results: </strong>A total of 919 TEs in 524 patients were analyzed: 27.7% with PDO mesh, 52.9% with biologic mesh, and 19.5% with no mesh. TE infection occurred in 70 breasts (7.6%) in 55 patients (10.5%), with infection rates of 10.6% in the PDO mesh group, 6.6% in the biologic mesh group, and 6.2% in the no mesh group (P = NS). Ipsilateral radiation exposure was the only factor significantly associated with infection (odds ratio, 7.2; P = .008). Prepectoral reconstructions resulted in higher infection rates than subpectoral cases, but mesh type was not independently associated with infection. Explantation occurred in 120 breasts (13.0%) with no difference between mesh types.</p><p><strong>Conclusions: </strong>Short-term outcomes following TE placement were comparable among patients receiving PDO mesh, biologic mesh, or no mesh. These findings suggest that mastectomy flap quality and patient factors may have a greater impact on complications than mesh type, especially with prepectoral placement.</p><p><strong>Level of evidence: 3 (therapeutic): </strong>For image description, please refer to the figure legend and surrounding text.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"1101-1108"},"PeriodicalIF":4.2,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13577730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146040319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"SVF-Enriched Versus Standard Fat Grafting for Breast Reconstruction and Augmentation: A Prospective Multicenter Comparative Randomized Study.","authors":"Pietro Gentile, Aris Sterodimas","doi":"10.1093/asj/sjag197","DOIUrl":"https://doi.org/10.1093/asj/sjag197","url":null,"abstract":"<p><strong>Background: </strong>Autologous fat grafting (AFG) has become a technique in aesthetic and reconstructive breast surgery. However, graft retention remains variable and requires repeated procedures. Stromal vascular fraction (SVF) enrichment has been proposed to improve graft survival through angiogenesis and tissue integration, although comparative evidence remains limited.</p><p><strong>Objectives: </strong>The endpoint was MRI-based graft retention at 12 months. Secondary outcomes included 24-month retention, complications, BREAST-Q outcomes, radiologic findings, and revision procedures. MRI volumetric assessment was performed using 3-dimensional segmentation protocols and analyzed by breast radiologists.</p><p><strong>Methods: </strong>A multicenter, randomized controlled study was conducted across six centers between January 2021 and March 2025. Patients affected by bilateral breast hypoplasia, breast asymmetry associated with unilateral breast hypoplasia, breast ptosis/pseudoptosis, and post-lumpectomy defects were randomized to standard AFG or SVF-enriched AFG.</p><p><strong>Results: </strong>312 patients were randomized (156 per group). Follow-up was 28.6 ± 6.4 months. At 12 months, MRI graft retention was greater in the SVF-enriched group compared with standard fat grafting (71.8% ± 11.2% versus 56.4% ± 13.7%; p < 0.001). Retention persisted at 24 months (66.2% ± 12.0% versus 49.8% ± 14.1%; p < 0.001). BREAST-Q scores were higher in the SVF group at both follow-up intervals. Fat necrosis and oil cyst formation rates were similar between groups. No suspicious MRI findings attributable to fat grafting were identified during follow-up.</p><p><strong>Conclusions: </strong>SVF-enriched AFG demonstrated improved volumetric persistence and higher patient-reported satisfaction compared with standard AFG, without increased radiologic or clinical complications. MRI-based evaluation may improve reproducibility in future breast fat grafting studies.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148966188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Max Mandelbaum, Isaac Mordukhovich, Neel Vishwanath, Elad Fraiman, Osama Darras, Viren Patel, Nicholas R Sinclair, James E Zins
{"title":"Interval to Secondary Facelift: A Match-Cohort Analysis of Interval Time, Technique, and Complications.","authors":"Max Mandelbaum, Isaac Mordukhovich, Neel Vishwanath, Elad Fraiman, Osama Darras, Viren Patel, Nicholas R Sinclair, James E Zins","doi":"10.1093/asj/sjag161","DOIUrl":"https://doi.org/10.1093/asj/sjag161","url":null,"abstract":"<p><strong>Background: </strong>Facelift surgery remains the most commonly performed aesthetic procedure among patients over 65 years of age, with the number of both primary and secondary procedures increasing in both younger and older populations. Although primary facelift techniques and outcomes are well described, comprehensive analyses of secondary facelifts remain limited.</p><p><strong>Objective: </strong>In a large matched retrospective cohort, we compare operative technique and safety between primary and secondary facelifts and assess interim timing as a proxy for longevity.</p><p><strong>Methods: </strong>Primary and secondary facelift patients treated by a single surgeon (J.E.Z.) between January 2014 and January 2024 were retrospectively matched by demographic and medical characteristics. Operative technique, adjunctive procedures, operative time, and major (unplanned admission, reoperation, and persistent motor nerve injury) and minor (outpatient-managed) complications were analyzed. Interim time between procedures was assessed to examine the relationship between age at primary surgery and durability.</p><p><strong>Results: </strong>Ninety-seven patients were included in each cohort. Secondary facelifts were 44.3 min shorter than primary facelifts (P < .01) and more likely to be performed with Superficial muscular aponeurotic system (SMAS)-plication (P < .01). Complication rates did not differ. The mean interval between primary and secondary facelifts was 10.7 ± 4.9 years. Younger ages at primary facelift correlated with longer interim intervals between primary and secondary facelifts (r = -0.44, P < .01).</p><p><strong>Conclusions: </strong>Secondary facelift surgery can be performed safely with complication rates comparable to primary procedures. An individualized operative strategy-employing sub-SMAS dissection when tissue quality permits and SMAS-plication when a more conservative approach is warranted-is supported. Younger age at primary surgery was associated with a significantly longer interval to secondary facelift.</p><p><strong>Level of evidence: 3 (risk): </strong>For image description, please refer to the figure legend and surrounding text.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148966151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Korneliusz Wójcik, Aleksandra Morajko, Magdalena Kozicka, Patryk Ostrowski, Marek Paul
{"title":"Assessment of Women's Quality of Life Following Primary Breast Augmentation Based on a Validated Polish Breast-Q Survey.","authors":"Korneliusz Wójcik, Aleksandra Morajko, Magdalena Kozicka, Patryk Ostrowski, Marek Paul","doi":"10.1093/asj/sjag192","DOIUrl":"https://doi.org/10.1093/asj/sjag192","url":null,"abstract":"<p><strong>Background: </strong>Breast augmentation is among the most performed plastic surgeries worldwide, with growing relevance for both aesthetic enhancement and psychological well-being. This study aimed to evaluate the impact of primary breast augmentation on patients' life satisfaction.</p><p><strong>Methods: </strong>A prospective study was conducted in 44 women undergoing primary breast augmentation. Outcomes were assessed using the validated Polish version of the BREAST-Q questionnaire preoperatively and at 3, 6, and 12 months postoperatively. Changes over time and correlations between domains were analyzed.</p><p><strong>Results: </strong>Significant improvements in quality of life were observed, particularly in psychosocial and sexual well-being. Psychosocial well-being increased from 50.8 ± 19.8 preoperatively to 91.5 ± 12.6 at 12 months, while sexual well-being improved from 47.1 ± 22.9 to 87.5 ± 14.9. Physical well-being showed a transient decline at 3 months, followed by recovery to near-baseline levels at 12 months. Satisfaction with breasts increased markedly over time. The procedure demonstrated a low complication rate, with one major complication and no cases requiring reoperation.</p><p><strong>Conclusions: </strong>Primary breast augmentation leads to significant and sustained improvements in patient-reported quality of life and satisfaction. Despite a transient decline in physical well-being, recovery occurs over time. These findings support breast augmentation as a safe and effective intervention for improving patient-reported outcomes.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148966200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimizing Outcomes in Thick-Skinned Rhinoplasty: Surgical Maneuvers and Perioperative Medical Management-A Narrative Review.","authors":"Nuray Bayar Muluk","doi":"10.1093/asj/sjag196","DOIUrl":"https://doi.org/10.1093/asj/sjag196","url":null,"abstract":"<p><p>Managing the dense nasal soft tissue envelope (STE) remains a formidable challenge in facial plastic surgery. This narrative review aims to evaluate the anatomical challenges associated with thick-skinned rhinoplasty, review intraoperative structural maneuvers, and assess the efficacy of perioperative medical interventions-specifically isotretinoin. A comprehensive literature search was conducted utilizing PubMed/Medline, Scopus, Web of Science, and Embase, yielding literature on anatomical variations, surgical techniques, and medical management. Thick nasal skin is inherently inelastic, predisposing patients to prolonged postoperative edema, increased dead space, and the masking of underlying cartilaginous definition. The reviewed literature suggests that intraoperative strategies relying heavily on robust structural grafting (e.g., columellar struts and septal extension grafts) demonstrate superior long-term projection compared to aggressive soft-tissue defatting alone, which carries risks of vascular compromise. Furthermore, the integration of preoperative skin conditioning and postoperative oral or topical isotretinoin appears to be a promising adjunct to diminish sebaceous gland activity and accelerate edema resolution. However, conclusions regarding isotretinoin must be moderated, as current studies are limited by small sample sizes, heterogeneous methodologies, and a lack of validated patient-reported outcome measures (e.g., FACE-Q). Achieving optimal results in thick-skinned rhinoplasty requires a multimodal approach. The synergistic combination of rigid intraoperative cartilaginous support, careful dead-space management, and judicious, patient-specific medical therapies may help mitigate postoperative fibrosis and improve aesthetic outcomes.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148954634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahshad Shamloo, Mohammad Rafiei, Atena Esmaeili, Farzad Zamani Barsari, Saeed Golparvaran, Ali Aalizade, Benyamin Rahmaty
{"title":"Oral Bromelain Reduces Postoperative Edema Following Upper Blepharoplasty: A Randomized Triple-Blind Placebo-Controlled Trial.","authors":"Mahshad Shamloo, Mohammad Rafiei, Atena Esmaeili, Farzad Zamani Barsari, Saeed Golparvaran, Ali Aalizade, Benyamin Rahmaty","doi":"10.1093/asj/sjag195","DOIUrl":"https://doi.org/10.1093/asj/sjag195","url":null,"abstract":"<p><strong>Background: </strong>Periorbital edema and ecchymosis are common and distressing postoperative sequelae after blepharoplasty, often causing patient anxiety and delaying social recovery. Bromelain, a proteolytic enzyme from pineapple, is known for its anti-inflammatory and anti-edematous effects.</p><p><strong>Objective: </strong>To investigate the efficacy of oral bromelain in reducing postoperative edema and ecchymosis after upper blepharoplasty.</p><p><strong>Methods: </strong>This randomized, triple-blind, placebo-controlled clinical trial was performed at our tertiary center. Forty-six blepharoplasty candidates were randomly assigned to two groups of 23: the intervention group received bromelain capsules (200 mg, equivalent to 500 GDU) every 8 hours, while the control group received identical placebo capsules containing starch for 2 weeks. The severity of edema and ecchymosis was evaluated on postoperative days 1, 3, 7, and 11 using a validated photographic grading scale (grades 1-4).</p><p><strong>Results: </strong>Both groups had similar baseline demographic characteristics (p>0.05). The bromelain group showed significantly lower edema scores on days 3, 7, and 11 (p<0.001, p=0.0002, and p=0.001, respectively). Ecchymosis scores were significantly reduced on day 3 (p=0.0002), but there were no significant differences between groups on days 7 and 11. Similarly, adverse effects did not differ significantly between the two groups.</p><p><strong>Conclusion: </strong>Oral bromelain markedly reduces swelling after blepharoplasty and has a notable effect on ecchymosis during the early recovery period. It may represent a safe and effective postoperative adjunct following upper blepharoplasty, although larger multicenter trials are required.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148954684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-Term Outcomes and Complication Profile After Modern Liposuction: A Multicenter Prospective Cohort Study with Five-Year Follow-up.","authors":"Pietro Gentile, Aris Sterodimas","doi":"10.1093/asj/sjag193","DOIUrl":"https://doi.org/10.1093/asj/sjag193","url":null,"abstract":"<p><strong>Background: </strong>Liposuction is among the most frequently performed aesthetic surgical procedures worldwide. Although short-term safety has improved with modern technologies and protocols, robust long-term prospective data regarding contour durability, weight stability, satisfaction, and complications remain limited.</p><p><strong>Objectives: </strong>This study evaluated long-term aesthetic outcomes, body contour stability, patient satisfaction, weight changes, and complications after modern liposuction using standardized clinical, photographic, and patient-reported assessments.</p><p><strong>Methods: </strong>A prospective multicenter cohort study was conducted across 8 tertiary plastic surgery centers. Patients undergoing abdominal, flank, thigh, back, or circumferential liposuction were enrolled between January 2016 and December 2019 and followed through December 2024. Primary endpoints included contour improvement, maintenance, and complication rates. Secondary outcomes included BODY-Q scores, revision surgery, weight variation, skin quality changes, and predictors of complications. Standardized photography and anthropometric measurements were obtained at baseline, 6 months, 1 year, 3 years, and 5 years. Statistical analyses included Kaplan-Meier analysis, multivariate logistic regression, and repeated-measures mixed models.</p><p><strong>Results: </strong>A total of 1,248 patients were included, with a mean follow-up of 52.4 ± 11.6 months. Mean aspirated fat volume was 3,180 ± 920 mL. Stable contour improvement was maintained in 78.6% at 5 years. BODY-Q scores improved significantly from baseline (p < 0.001). Overall complication rate was 14.8%, with major complications in 1.9%. The most frequent complications were contour irregularities (5.8%), edema (4.9%), seroma (2.6%), and fibrosis (2.3%). Revision surgery was required in 8.7%. High BMI, smoking, aspirate volume >5 L, and combined procedures predicted complications.</p><p><strong>Conclusions: </strong>Modern liposuction provides durable improvement and high satisfaction with low major complication rates.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andreas Larsen, Ole Østergaard, Tim Kongsmark Weltz, John Vinh Quang Tran, Erik Eiler Frydshou Bak, Linda Regína Guðjónsdóttir, Mathilde Nejrup Hemmingsen, Mathias Ørholt, Peter Vester-Glowinski, Anders Woetmann, Jesper Velgaard Olsen, Mikkel Herly
{"title":"Proteomic Profiling of Breast Implant Capsules: a Novel Approach for Studying Biocompatibility and Capsular Contracture.","authors":"Andreas Larsen, Ole Østergaard, Tim Kongsmark Weltz, John Vinh Quang Tran, Erik Eiler Frydshou Bak, Linda Regína Guðjónsdóttir, Mathilde Nejrup Hemmingsen, Mathias Ørholt, Peter Vester-Glowinski, Anders Woetmann, Jesper Velgaard Olsen, Mikkel Herly","doi":"10.1093/asj/sjag186","DOIUrl":"https://doi.org/10.1093/asj/sjag186","url":null,"abstract":"<p><strong>Background: </strong>Standardized molecular methods to assess the host response to breast implants are lacking. Mass spectrometry-based proteomics offers an unbiased approach to characterize the capsule proteome and the foreign-body response.</p><p><strong>Objectives: </strong>To establish proof-of-concept for deep proteomic profiling of human breast implant capsule tissue and explore the proteomic profile associated with capsular contracture.</p><p><strong>Methods: </strong>Capsule biopsies were obtained from women with capsular contracture (Baker III/IV, n = 24) and non-contracture controls (Baker I, n = 24). Proteomic profiles were analyzed by liquid chromatography-tandem mass spectrometry with label-free quantification. Differential expression, co-expression network, and functional enrichment analyses were performed, and capsules were additionally scored with a validated histopathological system.</p><p><strong>Results: </strong>Deep proteomic profiling quantified 7,258 proteins (median 5,879 per sample). Unsupervised analyses separated contracture from control samples without prior grouping information, indicating a distinct contracture-associated proteome (P = 0.001). We identified 77 differentially expressed proteins (31 upregulated, 46 downregulated). Extracellular matrix (ECM) remodeling dominated, with upregulation of MMP9 and inhibitors TIMP1 and TIMP3. A profibrotic TGF-β signature included THBS1, THBS2, periostin, and TGM2, and innate immune activation included MPO, FCGR1A, S100A8, and S100A9. Co-expression network analysis identified a contracture-associated neutrophil degranulation module, and an adaptive immune module linked to implantation time and rupture.</p><p><strong>Conclusion: </strong>Deep proteomic profiling of human breast implant capsules is feasible and revealed a contracture-associated proteomic phenotype dominated by ECM dysregulation, a profibrotic TGF-beta axis, and innate and adaptive immune activation. These findings provide proof-of-concept for capsule proteomics as a tool to study the host response to breast implants.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148917981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Burcu Celet Ozden, Gamze Aytas Sevindik, Nilufer Yildirim, Cem Yilmaz, Hasan Karanlik, Tugba Gun Koplay, Abdullah Igci
{"title":"Prepectoral Direct-to-implant Breast Reconstruction Without ADM or Mesh: A Prospective Single-surgeon Series of 210 Patients and 349 Breasts.","authors":"Burcu Celet Ozden, Gamze Aytas Sevindik, Nilufer Yildirim, Cem Yilmaz, Hasan Karanlik, Tugba Gun Koplay, Abdullah Igci","doi":"10.1093/asj/sjag191","DOIUrl":"https://doi.org/10.1093/asj/sjag191","url":null,"abstract":"<p><strong>Background: </strong>Prepectoral breast reconstruction reduces postoperative morbidity and eliminates animation deformity. Although acellular dermal matrices (ADM) and mesh have traditionally been used to stabilize prepectoral implants, emerging evidence has questioned their value and highlighted their association with postoperative complications.</p><p><strong>Objectives: </strong>This study presents a single-surgeon experience using 4-micron surface implants without ADM or mesh in immediate prepectoral direct-to-implant reconstruction.</p><p><strong>Methods: </strong>This is a prospective single-center, single-surgeon study involving patients who underwent immediate prepectoral, breast reconstruction using Motiva Ergonomix2 implants, between September 2023 and March 2025. Early and mid-term complications, aesthetic outcomes, and patient-reported satisfaction (BREAST-Q) were analyzed.</p><p><strong>Results: </strong>A total of 210 consecutive patients (349 breasts) underwent this surgical procedure with a median follow-up of 12 months (range: 3 to 21 months). Early complications occurred in 26.1% of breasts, most commonly incision dehiscence (5.2%), hematoma (3.7%), and partial nipple-areola-complex (NAC) necrosis (2.9%). Capsular contracture (Grade III/IV) occurred in 7.7% and implant rippling in 6%. Twenty-eight breasts (8%) required unplanned reoperation. Total implant loss occurred in 1.1% of breasts. Cosmetic outcomes (n=143) were rated \"excellent\" or \"good\" in >75% of cases, approaching 92% in bilateral prophylactic mastectomies. BREAST-Q responses (n=129) demonstrated a postoperative breast satisfaction score of 64.96%, and implant satisfaction of 6.6/8.</p><p><strong>Conclusions: </strong>This technique demonstrates low complication and implant loss rates, satisfactory aesthetic results, and high patient-reported satisfaction. These findings support Ergonomix2 implants as a safe, biocompatible, and potentially cost-effective option for prepectoral reconstruction.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148928887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}