Maissa Trabilsy, Arianna Genovese, Srinivasagam Prabha, Sahar Borna, Cesar A Gomez-Cabello, Syed Ali Haider, Cui Tao, Antonio J Forte
{"title":"Response to: Critical Evaluation of Generative Text-to-Image AI Models in Plastic Surgery: Balancing Promise and Precision.","authors":"Maissa Trabilsy, Arianna Genovese, Srinivasagam Prabha, Sahar Borna, Cesar A Gomez-Cabello, Syed Ali Haider, Cui Tao, Antonio J Forte","doi":"10.1093/asj/sjaf106","DOIUrl":"https://doi.org/10.1093/asj/sjaf106","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhanced Scar Reduction with Triamcinolone Acetonide and Botulinum Toxin A Combination Therapy Compared to Botulinum Toxin A Monotherapy: A Translational Pilot Study.","authors":"Shu-Hung Huang, Wen-Chin Wang, Hui-Yu Chuang, Shih-Ming Yang, Shang-Yu Yang, Sheng-Hua Wu","doi":"10.1093/asj/sjaf094","DOIUrl":"https://doi.org/10.1093/asj/sjaf094","url":null,"abstract":"<p><strong>Background: </strong>The efficacy of combining triamcinolone acetonide (TAC) and botulinum toxin type A (BTX-A) in treating hypertrophic scars and keloids remains unclear.</p><p><strong>Objectives: </strong>This pilot study aimed to compare the clinical efficacy of BTX-A monotherapy and TAC + BTX-A combination therapy in improving scar conditions and to investigate potential mechanisms using a rat burn scar model.</p><p><strong>Methods: </strong>This study was conducted between March 2022 and December 2024. Each patient's scar was randomly divided into two equal parts, with one part receiving TAC + BTX-A and the other BTX-A alone for three sessions at four-week intervals. Scar thickness was measured using calipers, and the Vancouver Scar Scale (VSS) was used to assess scar condition. Pain and itchiness were evaluated using the Numeric Rating Scale (NRS) and Visual Analog Scale (VAS), respectively, before each intervention (V1, V2, V3) and four weeks after the last session (V4). In the animal study, rats with burn scars were assigned to five groups: sham, untreated burn, TAC, BTX-A, and TAC + BTX-A. Scar thickness and expressions of α-SMA, TGF-β, CTGF, collagen I/III, laminin, and fibronectin were analyzed histologically.</p><p><strong>Results: </strong>Clinically, both therapies reduced scar thickness, VSS, NRS, and VAS scores. However, combination therapy showed superior reductions in scar thickness (V2-V4) and VSS scores (V3, V4) compared to BTX-A monotherapy. No significant differences were observed in NRS and VAS scores. The animal study confirmed that combination therapy more effectively reduced scar thickness, TGF-β and CTGF levels, and the collagen I/III ratio, while increasing the laminin/fibronectin ratio.</p><p><strong>Conclusions: </strong>TAC + BTX-A combination therapy enhances scar reduction by more effectively suppressing fibroblast proliferation and activation through TGF-β and CTGF downregulation, promoting scar remodeling.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary on: Same-Day Discharge Ambulatory Surgery Centers: The Importance of Preoperative Workup for Aesthetic Surgery Patient.","authors":"Javier Marull","doi":"10.1093/asj/sjaf105","DOIUrl":"https://doi.org/10.1093/asj/sjaf105","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Platelet-Derived Exosome Vulvar Injections for Sexual Dysfunction: A Retrospective Review.","authors":"Savas Ozgur Aglamis","doi":"10.1093/asj/sjaf104","DOIUrl":"https://doi.org/10.1093/asj/sjaf104","url":null,"abstract":"<p><strong>Background: </strong>PRP derived exosome has been used for a very long time in genital area rejuvenation applications.</p><p><strong>Objectives: </strong>The aim of this study is to investigate the effect of the newly defined genital PRP derived exosome injection point compared to conventional genital injection points.</p><p><strong>Methods: </strong>PRP derived exosome was taken into two one cc syringes. 4 injection areas were determined. Only 1 area was injected in each group. In Group A, a total of 2 cc of exosome was injected into the right and left lateral part of the clitoral glans at 3-9 o'clock with a 32 G 4 mm syringe tip. The procedure was applied so that the entire 4 mm syringe tip entered the tissue. In Group B, a total of 2 cc of exosome was injected into the G-spot area around the distal third of the anterior wall with a point-by-point technique with a 32 G 4 mm syringe tip. In group C, exosome injection was performed with a 32 G 4 mm syringe tip, 1 cc on the right side, 1 cc on the left side, and 2 cc in total, to the periurethral area. In group D, exosome injection was performed to the junction point of frenulum, prepuce, and labium minus and its surroundings, 1 cc on the right side, 1 cc on the left side, and 2 cc in total. This procedure was performed in 3 sessions, 4 weeks apart. All patients were evaluated with the FSFI scale before the 1st session and 6 and 12 months after the 3rd session.</p><p><strong>Results: </strong>The difference between the FSFI increase levels in two different periods for each group was evaluated. Accordingly, the FSFI increase in Group A was similar to the increase in Group D (p=0.715). The FSFI increase in Group B was similar to the increase in Group C (p=0.437). The FSFI increase in Groups A and D was statistically greater than the increase in Groups B and C (Group A vs Group B, p=0.001; Group A vs Group C, p=0.015; Group D vs Group B, p=0.027; Group D vs Group C, p=0.018).</p><p><strong>Conclusions: </strong>Our study is the first example in the literature in terms of evaluating the difference between the points where PRP-derived exosomes were applied. This new point injection increased FSFI better than group A and was as effective as groups B and C. The effectiveness of this newly defined method has been investigated with a single point injection point, and it is seen that the frequency of application will increase due to its easy applicability, low cost and low side effect rate.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuchen Zhang, Jiancong Liang, Haonan Xing, Yucheng Luo, Yuang Song, Ye Li, Bin Li, Feng Lu, Ziqing Dong
{"title":"Reflective Blankets vs. Electric Warming in Preventing Hypothermia During Liposuction: A Randomized Controlled Trial.","authors":"Yuchen Zhang, Jiancong Liang, Haonan Xing, Yucheng Luo, Yuang Song, Ye Li, Bin Li, Feng Lu, Ziqing Dong","doi":"10.1093/asj/sjaf103","DOIUrl":"https://doi.org/10.1093/asj/sjaf103","url":null,"abstract":"<p><strong>Background: </strong>Perioperative hypothermia is common during liposuction and can lead to delayed recovery, shivering and patient discomfort. While electric warming systems are effective, their use may be limited in certain settings.</p><p><strong>Objectives: </strong>To evaluate the effectiveness of reflective blankets in maintaining core temperature during liposuction, compared with electric warming and no warming.</p><p><strong>Methods: </strong>In this randomized controlled trial, 90 patients undergoing elective liposuction under general anesthesia were assigned to three groups (n=30): Reflective Blanket (RB), Electric Warming (EW), and Control (no warming). Core temperature was measured via esophageal probe. Secondary outcomes included awakening time, postoperative thermal comfort (VAS), shivering incidence and thermal imaging.</p><p><strong>Results: </strong>Baseline characteristics were similar across groups. Final intraoperative temperatures were higher in RB (36.37 ± 0.21°C) and EW (36.40 ± 0.17°C) groups than in Control (36.29 ± 0.17°C; p<0.05). EW provided earlier thermal protection; RB showed significant effects by 90 minutes. Shivering occurred in 76.7% of Control patients, versus 20.0% (RB) and 13.3% (EW) (p<0.001). Awakening time was shorter in RB (4.88 min) and EW (4.57 min) than in Control (7.72 min; p<0.001). Thermal imaging confirmed better heat retention with RB and EW.</p><p><strong>Conclusions: </strong>Reflective blankets are effective in maintaining normothermia during liposuction and improving recovery outcomes. Their low cost, ease of use and energy-free operation make them a practical alternative to electric warming, especially in resource-limited settings.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhancing Methodological Rigor in MFU-V Meta-analyses: A Commentary on Evidence Synthesis and Interpretation.","authors":"Rajesh Radhakrishnan, Mahesh Gore, Ashutosh Bhosale","doi":"10.1093/asj/sjaf101","DOIUrl":"https://doi.org/10.1093/asj/sjaf101","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Critical Evaluation of Generative Text-to-Image AI Models in Plastic Surgery: Balancing Promise and Precision.","authors":"Berk B Ozmen, Graham S Schwarz","doi":"10.1093/asj/sjaf098","DOIUrl":"https://doi.org/10.1093/asj/sjaf098","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144155524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara B A Morel, Luis H Macias, Ritu Chopra, Joshua Vorstenbosch, Tyler Safran
{"title":"Aesthetic Submandibular Gland Resection: A Review of Complication Incidence and Prevention.","authors":"Sara B A Morel, Luis H Macias, Ritu Chopra, Joshua Vorstenbosch, Tyler Safran","doi":"10.1093/asj/sjaf096","DOIUrl":"https://doi.org/10.1093/asj/sjaf096","url":null,"abstract":"<p><p>Achieving optimal neck contour during facial rejuvenation may require addressing the submandibular glands, as supraplatysmal fat removal alone is insufficient for many patients, particularly those with fuller necks. The purpose of this study is to review the rate of complications associated with removal and techniques to improve safety. A comprehensive search was conducted to identify literature on complications associated with submandibular gland removal in the context of facial rejuvenation. Studies were included if they provided patient data and complication rates following surgical outcomes. Screening of 908 articles identified 11 (1.21%) studies on complication rates related to submandibular gland resection for aesthetic purposes. A total of 3379 participants were included, of which 48.86% (n=1651) underwent submandibular gland resection, with a mean age of 50.4 years (range 32-83), and 88.53% (n=247) were female. Complications included hematomas (1.15%, n=16), requiring reoperation in 23.08% (n=3) of cases, sialoceles (1.33%, n=21), salivary fistulas (0.82%, n=6), nerve injury (3.97%, n=40), xerostomia (0.13%, n=1), and neck induration (21.43%, n=21), with complication rates varying across studies. Submandibular gland reduction offers aesthetic benefits but comes with potential risks. Effective preoperative planning, meticulous gland mobilization, and proper exposure are essential for minimizing risks. Advances in techniques, such as improved dissection methods, the use of botulinum toxin, netting techniques, and energy-based instruments like LigaSure, have enhanced the safety of the procedure. While complications can arise, they typically resolve within a few months, and the overall outcomes improve with surgical experience. The associated risks and benefit profile should be discussed thoroughly with patients.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giorgio Caddia, Delphine Voulliaume, Laura Dettori, Corrado Rubino, Emmanuel Delay
{"title":"Post-surgical Pyoderma Gangrenosum in Breast Surgery: An Updated Systematic Review, Takeaways, and the 6 Commandments.","authors":"Giorgio Caddia, Delphine Voulliaume, Laura Dettori, Corrado Rubino, Emmanuel Delay","doi":"10.1093/asj/sjaf095","DOIUrl":"https://doi.org/10.1093/asj/sjaf095","url":null,"abstract":"<p><strong>Background: </strong>Post-surgical pyoderma gangrenosum (PSPG) is a rare and under-recognized inflammatory dermatosis that can develop after surgery. When it occurs following breast procedures, its clinical presentation often mimics surgical site infection or necrosis, leading to delayed diagnosis and inappropriate treatment, with potentially severe aesthetic and functional consequences.</p><p><strong>Objectives: </strong>To update the literature on PSPG following reconstructive and aesthetic breast surgery and to provide clinicians with practical tools for early recognition and management, including clinical red flags, a diagnostic framework, and therapeutic guidelines.</p><p><strong>Methods: </strong>A systematic review was conducted in March 2025 according to PRISMA guidelines, updating the work of Ehrl et al. by including studies published from 2017 onward. Data from 65 new cases were extracted and analyzed descriptively. We also report three institutional cases and one case of recurrence to provide additional clinical insight.</p><p><strong>Results: </strong>A total of 65 new PSPG cases were identified across 45 studies, for a cumulative total of 152. Reduction mammoplasty was the most frequent surgical trigger. The condition involved multiple sites in 71.4% of combined breast-abdominal procedures. Pain was the most common symptom (86.2%), and the nipple-areola complex was spared in 80.7% of cases. C-reactive protein was often elevated (>200 mg/L), and microbiological cultures were negative in 76.9% of cases. Systemic corticosteroids were the most effective treatment. Mean healing time was 4.5 months; surgical reconstruction was needed in 29% of cases.</p><p><strong>Conclusions: </strong>PSPG remains a diagnostic challenge with significant consequences if unrecognized. Key clues include exaggerated postoperative pain, NAC sparing, elevated CRP, and poor response to antibiotics. We propose a practical flowchart and summarize six core management principles. Preoperative counseling and informed consent, particularly in reduction mammoplasty, should include this rare but serious complication.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aesthetic Surgery Journal Welcomes the Kuwait Plastic Surgery Society.","authors":"Hisham Burezq, Jeffrey M Kenkel","doi":"10.1093/asj/sjaf087","DOIUrl":"https://doi.org/10.1093/asj/sjaf087","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}