Aesthetic Surgery Journal最新文献

{"title":"Critical Considerations on Polyurethane-coated Implants in Breast Reconstruction.","authors":"Manuel Cabrera Charleston, Daniela Guadalupe Oscura Paredes","doi":"10.1093/asj/sjaf171","DOIUrl":"https://doi.org/10.1093/asj/sjaf171","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Montelukast vs Tranilast Administration in the Prevention of Capsular Contracture in Alloplastic Breast Surgeries: An Experimental Mice Model.","authors":"Yidan Xu, Shujie Xu, Han Yang, Yuchen Zhang, Cheng Zhou, Feng Lu, Jianhua Gao, Yao Yao","doi":"10.1093/asj/sjaf143","DOIUrl":"https://doi.org/10.1093/asj/sjaf143","url":null,"abstract":"<p><strong>Background: </strong>Capsular contracture remains a prevalent complication following breast implant augmentation. Despite growing interest in pharmacological prevention, optimal drug selection and administration timing remain unclear.</p><p><strong>Objectives: </strong>The authors of this study aim to compare the efficacy of tranilast vs montelukast and evaluate prophylactic vs postoperative administration in preventing capsular contracture.</p><p><strong>Methods: </strong>Eighty male C57BL/6J mice were randomized into 5 groups: control, post-montelukast, pre-montelukast, post-tranilast, and pre-tranilast. For 1 preoperative month, the control group received daily saline (1 mL) through gavage, whereas drug-treated groups received montelukast (10 mg/kg/day) or tranilast (50 mg/kg/day). Prophylactic groups initiated drug administration preoperatively. Miniature implants were bilaterally placed dorsally, followed by 3 months of postoperative drug continuation. Histopathological evaluation assessed capsule thickness, macrophage infiltration, collagen density, and inflammatory response.</p><p><strong>Results: </strong>At 90 days post surgery, all drug interventions significantly reduced capsular thickness compared with the control group (control: 232.4 ± 43 μm; post-montelukast: 137.5 ± 24 μm; pre-montelukast: 107.7 ± 20 μm; post-tranilast: 93.3 ± 22 μm; pre-tranilast: 70.2 ± 11 μm; P < .0001). The pre-tranilast group demonstrated the lowest collagen deposition at 90 days (16.0 ± 5% vs control: 76.6 ± 13%; P < .001). Pre-tranilast exhibited superior macrophage inhibitory effects compared with post-tranilast administration. Furthermore, tranilast outperformed montelukast in efficacy regardless of administration timing.</p><p><strong>Conclusions: </strong>Prophylactic tranilast administration significantly attenuates capsular contracture by reducing inflammation, macrophage infiltration, and collagen deposition, surpassing both postoperative tranilast and montelukast. These findings support prioritizing preoperative tranilast in clinical trials to improve breast implant outcomes.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Computed Tomography Indicates No Negative Impact of OnabotulinumtoxinA on Mandibular Bone Density in a 12-Month, Double-Blind, Randomized, Repeat Treatment, Placebo-Controlled Study in Healthy Adults With Masseter Muscle Prominence.","authors":"Paul Kostenuik, Sanjay M Mallya, René Hopfinger, Tara Aghaloo, Shawneen Gonzalez, James Mah, Mansur Ahmad, Grace Pan, Donna L Faletto, Elisabeth Lee, Beta Bowen, Mitchell F Brin","doi":"10.1093/asj/sjaf167","DOIUrl":"https://doi.org/10.1093/asj/sjaf167","url":null,"abstract":"<p><strong>Background: </strong>Botulinum neurotoxins are used to treat masseter muscle prominence (MMP), benign bilateral masseter muscle enlargement which can be aesthetically undesirable. Limited data report botulinum neurotoxin injections in the muscles of mastication, with subsequent reduction in biomechanical loading, may impact mandibular bone density.</p><p><strong>Objectives: </strong>This study evaluates whether changes in mandibular bone density occur after bilateral masseter treatment with a botulinum neurotoxin, onabotulinumtoxinA, in individuals with MMP.</p><p><strong>Methods: </strong>Analyses were performed on a prespecified subpopulation (n=123) from a 12-month, double-blind, placebo-controlled, dose-escalation, Phase 2 study (N=187). Participants received 1 or 2 bilateral masseter treatments of onabotulinumtoxinA (48, 72, or 96 U) or placebo and had multi-detector computed tomography (MDCT) scans at baseline and Days 90 and 360 post-treatment. Cortical and trabecular bone densities, estimated in Hounsfield units, were calculated for the bilateral condyle, premolar dentoalveolus, and ramus.</p><p><strong>Results: </strong>No clinically significant changes in mandibular bone density were observed in condyle, premolar area, or ramus of onabotulinumtoxinA-treated participants, as compared to placebo or baseline, after 1 or 2 treatments.</p><p><strong>Conclusions: </strong>In healthy adults with MMP, 1 or 2 bilateral masseter treatments with onabotulinumtoxinA at doses of 48, 72, or 96 U over 1 year did not negatively impact mandibular bone density.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The First Aesthetic Surgery Consultation: A Professional Act That Should Be Valued-At Every Stage of a Surgeon's Career.","authors":"Paolo Montemurro","doi":"10.1093/asj/sjaf170","DOIUrl":"https://doi.org/10.1093/asj/sjaf170","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The BODY-Q Belly Button Scale: A Development and Validation Study.","authors":"Farima Dalaei, Claire E E de Vries, Charlene Rae, Trisia Breitkopf, Danny Mou, Maarten Hoogbergen, Jens Ahm Sørensen, Andrea L Pusic, Anne F Klassen","doi":"10.1093/asj/sjaf159","DOIUrl":"https://doi.org/10.1093/asj/sjaf159","url":null,"abstract":"<p><strong>Background: </strong>One of the critical steps in abdominoplasty or reconstructive procedures using abdominal tissue involves repositioning the belly button. However, there is limited knowledge about patient satisfaction regarding the appearance of the belly button after such procedures. Currently, there is no standardized patient-reported outcome measure designed to assess this outcome.</p><p><strong>Objectives: </strong>This study aimed to develop and validate a BODY-Q scale that measures patient satisfaction with the appearance of the belly button.</p><p><strong>Methods: </strong>In phase 1 (qualitative), patient interviews were used to develop and refine the new BODY-Q scale. In phase 2 (quantitative), the scale was field-tested through a crowdsourcing platform. Rasch measurement theory (RMT) analysis was used for item reduction and to examine reliability and validity. Predefined hypotheses were tested using a 75 percent acceptance threshold, which was considered indicative of sufficient evidence for construct validity.</p><p><strong>Results: </strong>The Belly Button scale was refined through qualitative input from five patients. Psychometric validation was performed in a sample of 372 participants. From 15 items, six items were retained in the final scale. This scale showed ordered thresholds and data fit the Rasch model (χ2 = 22.72, df = 24, p-value = 0.54). The scale evidenced reliability with Person Separation Index and Cronbach alpha values >0.81. For construct validity, acceptance of hypotheses was 89 percent.</p><p><strong>Conclusions: </strong>The BODY-Q Belly Button scale can be used in clinical practice and in research to assess satisfaction with the belly button from the patient's perspective.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fat Graft Replacement for Reducing Implant Size May Decrease Radiotherapy-Related Complications in Prepectoral Expander-to-Implant Breast Reconstruction.","authors":"Munur Selcuk Kendir, Majid Ismayilzade","doi":"10.1093/asj/sjaf166","DOIUrl":"10.1093/asj/sjaf166","url":null,"abstract":"<p><strong>Background: </strong>There is obvious requirement for the improvement of expander-to-implant breast reconstruction due to the high rate of complication caused by radiotherapy.</p><p><strong>Objectives: </strong>We aimed to decrease the complications by applying fat graft to obtain thicker mastectomy flaps and more importantly, to replace the part of definitive implant volume with fat tissue.</p><p><strong>Methods: </strong>Patients who underwent immediate pre-pectoral expander-to-implant placement for breast reconstruction were included in the study. In the fat graft group, two sessions of fat grafting procedure were applied after radiotherapy to decrease the volume of definitive implant while no additional intervention was executed to the no fat graft group. Patients were evaluated for wound dehiscence, skin necrosis, infection, implant loss, rippling, capsular contracture and secondary interventions.</p><p><strong>Results: </strong>The fat graft group demonstrated statistically significantly lower incidence of wound dehiscence, skin necrosis, infection, implant loss, rippling, and capsular contracture compared to the no fat graft group (P < 0,05), despite similar baseline characteristics and reconstructive protocols.</p><p><strong>Conclusions: </strong>Autologous fat grafting prior to implant exchange was associated with a substantial reduction in the rates of wound dehiscence, skin necrosis, infection, implant loss, rippling and capsular contracture compared to standard implant exchange without fat grafting in prepectoral breast reconstruction.</p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to: Beyond PlasticSurgeryGPT: The Imperative for Reasoning-enhanced LLMs in Plastic Surgery.","authors":"Berk B Ozmen, Ibrahim Berber, Graham S Schwarz","doi":"10.1093/asj/sjaf164","DOIUrl":"10.1093/asj/sjaf164","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Retrospective Case Series Study of Illegal Cosmetic Iatrogenic Botulism: Outbreak Analysis and Response Lessons.","authors":"He Qiu, Jiang Shen, Yali Tang, Qiang Ji, Xiaoqun Lin, Dongmei Wu","doi":"10.1093/asj/sjaf088","DOIUrl":"10.1093/asj/sjaf088","url":null,"abstract":"<p><strong>Background: </strong>Botulism is a rare and possibly life-threatening neuroparalytic syndrome. Recent large-scale outbreaks of iatrogenic botulism, primarily linked to cosmetic injections, have garnered significant attention.</p><p><strong>Objectives: </strong>This study discusses the factors that may lead to the outbreak of cosmetic iatrogenic botulism (CIB), provides the epidemiological description of CIB cases, and puts forward response measures.</p><p><strong>Methods: </strong>All clinical data, laboratory investigations, and therapeutic procedures of CIB patients in a large single-center retrospective cohort (2014-2024) were reviewed and analyzed.</p><p><strong>Results: </strong>Over a 10-year period, 161 cases of CIB were identified, of which 80 (49.69%) were hospitalized and 81 (50.31%) were outpatient cases. Most patients received botulinum toxin (BoNT) injections of unknown origin from unlicensed practitioners in nonmedical settings. Severe and moderate cases of CIB accounted for up to 60%, with the majority of outbreaks occurring in 2024. The median time from botulism onset was 0 to 17 days, with the highest incidence occurring within 3 days following the injection. Hospitalized patients were discharged after a mean of 11.64 ± 9.40 days (range, 1-39 days), and symptoms resolved in botulism patients within a mean of 24.85 ± 11.67 days following treatment. Treatments included antitoxin administration, hyperbaric oxygen therapy, pyridostigmine, other symptomatic treatment, and supportive care.</p><p><strong>Conclusions: </strong>This represents the largest reported outbreak of illicit CIB worldwide, highlighting the risks associated with counterfeit BoNT, noncompliant practices, and underscoring the critical need for stringent surveillance of BoNT distribution. Clinicians should be adept at recognizing and adhering to the diagnosis, treatment, and follow-up management of CIB.</p><p><strong>Level of evidence: 4 (therapeutic): </strong></p>","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"936-946"},"PeriodicalIF":3.0,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to: Critical Evaluation of Generative Text-to-Image Artificial Intelligence Models in Plastic Surgery: Balancing Promise and Precision.","authors":"Maissa Trabilsy, Ariana Genovese, Srinivasagam Prabha, Sahar Borna, Cesar A Gomez-Cabello, Syed Ali Haider, Cui Tao, Antonio J Forte","doi":"10.1093/asj/sjaf106","DOIUrl":"10.1093/asj/sjaf106","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"NP185-NP186"},"PeriodicalIF":3.0,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on: Same-Day Discharge Ambulatory Surgery Centers: The Importance of Preoperative Workup for Aesthetic Surgery Patients.","authors":"Javier Marull","doi":"10.1093/asj/sjaf105","DOIUrl":"10.1093/asj/sjaf105","url":null,"abstract":"","PeriodicalId":7728,"journal":{"name":"Aesthetic Surgery Journal","volume":" ","pages":"965-966"},"PeriodicalIF":3.0,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}