Aging Clinical and Experimental Research最新文献_第9页

Investigation of nutrition status and analysis of 180-day readmission factors in elderly hospitalized patients with COPD 慢性阻塞性肺病老年住院患者的营养状况调查和 180 天再入院因素分析。

IF 3.4 3区医学

Aging Clinical and Experimental Research Pub Date : 2024-08-01 DOI: 10.1007/s40520-024-02820-9

Huan Liu, Jingsi Song, Zhiqiang Wang, Songze Wu, Shi Qiu, Benhui Chen, Zhiyong Rao, Xiaofan Jing

{"title":"Investigation of nutrition status and analysis of 180-day readmission factors in elderly hospitalized patients with COPD","authors":"Huan Liu, Jingsi Song, Zhiqiang Wang, Songze Wu, Shi Qiu, Benhui Chen, Zhiyong Rao, Xiaofan Jing","doi":"10.1007/s40520-024-02820-9","DOIUrl":"10.1007/s40520-024-02820-9","url":null,"abstract":"<div><h3>Background and objective</h3><p>Malnutrition is prevalent among elderly patients with COPD, who also experience a high rate of readmission. Therefore, it is imperative to investigate the nutrition status of these patients, identify risk factors for readmission, and offer insights for clinical management. To achieve this, a cross-sectional study was conducted to investigate factors influencing nutrition status using GLIM criteria and explore the 180-day readmission factors among hospitalized elderly COPD patients.</p><h3>Methords and results</h3><p>The data were collected from a hospital in Southwest China, encompassing a cohort of 319 eligible patients. Among elderly hospitalized COPD patients, the prevalence of malnutrition was 49.53% (158/319). Multivariate logistic regression revealed malnutrition (OR = 3.184), very severe airway obstruction (OR = 3.735), and Number of comorbidities ≥ 3 (OR = 5.754) as significant risk factors for 180-day readmission.</p><h3>Conclusions</h3><p>These findings suggest that malnutrition is a prevalent issue among elderly hospitalized patients with COPD and constitutes one of the risk factors contributing to the 180-day readmission rate. Therefore, timely identification and treatment for malnourished patients are crucial.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"36 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11291564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141858828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Meaning of home attenuates the relationship between functional limitations and active aging 家庭的意义削弱了功能限制与积极老龄化之间的关系。

IF 3.4 3区医学

Aging Clinical and Experimental Research Pub Date : 2024-08-01 DOI: 10.1007/s40520-024-02810-x

Björn Slaug, Magnus Zingmark, Marianne Granbom, Jonas Björk, Taina Rantanen, Steven M. Schmidt, Susanne Iwarsson

{"title":"Meaning of home attenuates the relationship between functional limitations and active aging","authors":"Björn Slaug, Magnus Zingmark, Marianne Granbom, Jonas Björk, Taina Rantanen, Steven M. Schmidt, Susanne Iwarsson","doi":"10.1007/s40520-024-02810-x","DOIUrl":"10.1007/s40520-024-02810-x","url":null,"abstract":"<div><h3>Background and aims</h3><p>Active aging is the process through which people strive to maintain wellbeing when growing old. Addressing the lack of research on active aging in the context of housing, the aim was to describe active aging among people aged 55 and older considering relocation and investigate whether perceived housing moderates the relationship between functional limitations and active aging.</p><h3>Methods</h3><p>We utilized cross-sectional data from a sub-sample (<i>N</i> = 820; mean age = 69.7; 54% women) of the Prospective RELOC-AGE. Functional limitations were reported using 10 dichotomous questions. Active aging was assessed with the University of Jyvaskyla Active Aging Scale (UJACAS; 17 items, self-rated for four perspectives). Perceived housing was self-rated with four usability questions and meaning of home (MOH; 28 items). Cross-sectional associations and interactions were analysed using linear regression models, adjusting for gender and educational level.</p><h3>Results</h3><p>Each functional limitation decreased the active aging score by almost five points (<i>p</i> < 0.001). Usability did not moderate that relationship while MOH significantly attenuated the association between functional limitations and active aging (<i>p</i> = 0.039). Those with high MOH had two points less decrease in active aging score compared to those with low MOH.</p><h3>Discussion and conclusions</h3><p>Having a home with more personal meaning attached to it seems to provide more ability and opportunity for meaningful activities, thus supporting active aging despite functional limitations. This sheds new light on the known association between MOH and different aspects of wellbeing in old age and has relevance for theory development, housing policies and housing counselling targeting younger older adults.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"36 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141858829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of intrinsic capacity decline among community-dwelling older adults: a systematic review and meta-analysis 社区老年人内在能力衰退的普遍性：系统回顾和荟萃分析。

IF 3.4 3区医学

Aging Clinical and Experimental Research Pub Date : 2024-08-01 DOI: 10.1007/s40520-024-02816-5

Xia Cao, Xuanzi Yi, Hui Chen, Yusheng Tian, Sihong Li, Jiansong Zhou

{"title":"Prevalence of intrinsic capacity decline among community-dwelling older adults: a systematic review and meta-analysis","authors":"Xia Cao, Xuanzi Yi, Hui Chen, Yusheng Tian, Sihong Li, Jiansong Zhou","doi":"10.1007/s40520-024-02816-5","DOIUrl":"10.1007/s40520-024-02816-5","url":null,"abstract":"<div><h3>Background</h3><p>The concept of intrinsic capacity (IC) was introduced to define healthy aging and active aging based on functional capacity, yet there is limited understanding of the risk of IC decline at a population level.</p><h3>Aims</h3><p>To consolidate existing evidence for rates of IC decline and risk factors among community-dwelling adults 60 years or older.</p><h3>Methods</h3><p>According to the PRISMA guidelines, the literature search was independently conducted by two researchers in 8 databases from inception to January 2024 without language restrictions using combinations of free words and subject words. Qualities of included studies were assessed using Joanna Briggs Institute’s (JBI’s) critical appraisal checklist for prevalence studies. To pool the data, a random-effect meta-analysis was performed, followed by subgroup analysis and sensitivity analysis. All analyses were performed by Stata14.0.</p><h3>Results</h3><p>From 1594 records, 15 studies were extracted with 33,070 participants for meta-analysis. The pooled prevalence of IC decline in community settings was 67.8% (95% CI: 57.0-78.5%; <i>P</i> < 0.001). The prevalence of IC decline in China (66.0%; 95% CI: 53.2-78.9%) was found to be slightly lower than in other countries/regions (73.0%; 95% CI: 59.8-86.3%); however, this difference was not statistically significant. Other subgroup analyses revealed no statistically significant differences in prevalence. Age, hypertension, diabetes, gender, education level, living status, smoking, regular exercise, marital status, and osteoarthritis are associated with IC decline.</p><h3>Conclusion</h3><p>More than two-thirds of older adults in the community are affected by IC decline, and age, hypertension, diabetes, female sex, low education level, living alone, smoking, irregular exercise, unmarried, and osteoarthritis are all risk factors for IC decline.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"36 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141858830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding healthy ageing in India: insights from multivariate regression trees 了解印度的健康老龄化：多变量回归树的启示。

IF 3.4 3区医学

Aging Clinical and Experimental Research Pub Date : 2024-08-01 DOI: 10.1007/s40520-024-02815-6

Ayushi Das, Preeti Dhillon

{"title":"Understanding healthy ageing in India: insights from multivariate regression trees","authors":"Ayushi Das, Preeti Dhillon","doi":"10.1007/s40520-024-02815-6","DOIUrl":"10.1007/s40520-024-02815-6","url":null,"abstract":"<div><h3>Background</h3><p>Population ageing represents a significant global challenge, particularly pronounced in countries like India.</p><h3>Aims</h3><p>This study aims to explore how factors such as socio-economic status, behaviour, and health influence healthy ageing across the Indian older population.</p><h3>Methods</h3><p>In this study, we utilized the Longitudinal Ageing Study in India – wave 1 dataset for analysis purposes. Scores were generated for five dimensions of healthy aging, including physical, functional, mental, cognitive, and social aspects and these scores were treated as the target variables. Multivariate Regression Trees analysis was employed to identify the behavioural and socio-demographic factors associated with each dimension of healthy ageing.</p><h3>Results</h3><p>Years of education emerge as crucial across all dimensions, positively impacting cognitive health and mitigating age-related decline in healthy ageing. Marital status, engagement in household activities, spiritual practices, and living arrangements impacts the scores of different aspects of healthy ageing. Gender disparities in healthy aging are noticeable in the 60–74 age group, with women generally having lower scores. Safety of the living environment is a crucial determinant of the mental health of the elderly across all age groups.These findings highlight the complex interplay of factors in healthy ageing outcomes.</p><h3>Conclusion</h3><p>Our study emphasizes the pivotal role of education in fostering healthy ageing in India. Factors such as environmental safety and social participation also influence well-being. Targeted interventions addressing education, gender equality, safety, and healthcare access are vital for enhancing the ageing experience and overall well-being of older adults.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"36 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141858831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of serum uric acid on bone and fracture risk in postmenopausal women 血清尿酸对绝经后妇女骨质和骨折风险的影响。

IF 3.4 3区医学

Aging Clinical and Experimental Research Pub Date : 2024-08-01 DOI: 10.1007/s40520-024-02819-2

María-Jesús Gómez-de-Tejada-Romero, Carmen Murias-Henríquez, Pedro Saavedra-Santana, Nery Sablón-González, Delvys Rodríguez Abreu, Manuel Sosa-Henríquez

{"title":"Influence of serum uric acid on bone and fracture risk in postmenopausal women","authors":"María-Jesús Gómez-de-Tejada-Romero, Carmen Murias-Henríquez, Pedro Saavedra-Santana, Nery Sablón-González, Delvys Rodríguez Abreu, Manuel Sosa-Henríquez","doi":"10.1007/s40520-024-02819-2","DOIUrl":"10.1007/s40520-024-02819-2","url":null,"abstract":"<div><h3>Aims</h3><p>Uric acid has been associated with several metabolic conditions, including bone diseases. Our objective here was to consider the relationship between serum uric acid levels and various bone parameters (bone mineral density, ultrasonographic parameters, vitamin D, PTH and serum calcium), as well as the prevalence and risk of fragility fracture.</p><h3>Methods</h3><p>An observational and cross-sectional study carried out on 679 postmenopausal women, classified into 3 groups according to their serum uric acid levels, in whom bone densitometry, calcaneus ultrasounds, PTH, vitamin D and serum calcium analysis were done. Bone fractures were collected through the clinical history and lateral spinal X-ray.</p><h3>Results</h3><p>Higher uric acid levels were found in women with older age, high BMI, diabetes, and high blood pressure. Higher levels of PTH and serum calcium were also observed, but did not effect on vitamin D. Serum uric acid was positively related to densitometric and ultrasonic parameters and negatively associated with vertebral fractures.</p><h3>Conclusions</h3><p>In the population of postmenopausal women studied, sUA levels were correlated with BMD, BUA, and QUI-Stiffness, and this correlation was independent of age and BMI. In addition, sUA was associated with a decrease in vertebral fractures. These results imply a beneficial influence of sUA on bone metabolism, with both a quantitative and qualitative positive effect, reflected in the lower prevalence of vertebral fractures.</p></div>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"36 1","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11291523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141858827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A mediation approach in resting-state connectivity between the medial prefrontal cortex and anterior cingulate in mild cognitive impairment. 轻度认知障碍患者内侧前额叶皮层与前扣带回之间静息状态连接的中介方法。

IF 3.4 3区医学

Aging Clinical and Experimental Research Pub Date : 2024-07-30 DOI: 10.1007/s40520-024-02805-8

Yiyuan Teresa Huang, Sui-Hing Yan, Yi-Fang Chuang, Yao-Chia Shih, Yan-Siang Huang, Yi-Chien Liu, Scott Shyh-Chang Kao, Yen-Ling Chiu, Yang-Teng Fan

{"title":"A mediation approach in resting-state connectivity between the medial prefrontal cortex and anterior cingulate in mild cognitive impairment.","authors":"Yiyuan Teresa Huang, Sui-Hing Yan, Yi-Fang Chuang, Yao-Chia Shih, Yan-Siang Huang, Yi-Chien Liu, Scott Shyh-Chang Kao, Yen-Ling Chiu, Yang-Teng Fan","doi":"10.1007/s40520-024-02805-8","DOIUrl":"10.1007/s40520-024-02805-8","url":null,"abstract":"<p><p>Mild cognitive impairment (MCI) is recognized as the prodromal phase of dementia, a condition that can be either maintained or reversed through timely medical interventions to prevent cognitive decline. Considerable studies using functional magnetic resonance imaging (fMRI) have indicated that altered activity in the medial prefrontal cortex (mPFC) serves as an indicator of various cognitive stages of aging. However, the impacts of intrinsic functional connectivity in the mPFC as a mediator on cognitive performance in individuals with and without MCI have not been fully understood. In this study, we recruited 42 MCI patients and 57 healthy controls, assessing their cognitive abilities and functional brain connectivity patterns through neuropsychological evaluations and resting-state fMRI, respectively. The MCI patients exhibited poorer performance on multiple neuropsychological tests compared to the healthy controls. At the neural level, functional connectivity between the mPFC and the anterior cingulate cortex (ACC) was significantly weaker in the MCI group and correlated with multiple neuropsychological test scores. The result of the mediation analysis further demonstrated that functional connectivity between the mPFC and ACC notably mediated the relationship between the MCI and semantic fluency performance. These findings suggest that altered mPFC-ACC connectivity may have a plausible causal influence on cognitive decline and provide implications for early identifications of neurodegenerative diseases and precise monitoring of disease progression.</p>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"36 1","pages":"154"},"PeriodicalIF":3.4,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141791697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An executive summary on the Global conceptual definition of Sarcopenia 关于 "肌肉疏松症 "全球概念定义的执行摘要

IF 4 3区医学

Aging Clinical and Experimental Research Pub Date : 2024-07-27 DOI: 10.1007/s40520-024-02798-4

Ben Kirk, Peggy M. Cawthon, Hidenori Arai, José A. Ávila-Funes, Rocco Barazzoni, Shalender Bhasin, Ellen F. Binder, Olivier Bruyère, Tommy Cederholm, Liang-Kung Chen, Cyrus Cooper, Gustavo Duque, Roger A. Fielding, Jack Guralnik, Douglas P. Kiel, Francesco Landi, Jean-Yves Reginster, Avan A. Sayer, Marjolein Visser, Stephan von Haehling, Jean Woo, Alfonso J. Cruz-Jentoft

引用次数: 0

An internally and externally validated nomogram for predicting cancer-specific survival in octogenarians after radical resection for colorectal cancer. 预测八旬老人结直肠癌根治术后癌症特异性生存率的内部和外部验证提名图。

IF 3.4 3区医学

Aging Clinical and Experimental Research Pub Date : 2024-07-26 DOI: 10.1007/s40520-024-02809-4

Junchang Zhu, Wei Cen, Xuzhi Zheng, Chenqiao Ye, Feifan Guo, Xialin Yan, Hongying Shi, Lechi Ye, Tingting Hu

{"title":"An internally and externally validated nomogram for predicting cancer-specific survival in octogenarians after radical resection for colorectal cancer.","authors":"Junchang Zhu, Wei Cen, Xuzhi Zheng, Chenqiao Ye, Feifan Guo, Xialin Yan, Hongying Shi, Lechi Ye, Tingting Hu","doi":"10.1007/s40520-024-02809-4","DOIUrl":"10.1007/s40520-024-02809-4","url":null,"abstract":"<p><strong>Aims: </strong>We aimed to develop an elaborative nomogram that predicts cancer-specific survival (CSS) in American and Chinese octogenarians treated with radical resection for CRC.</p><p><strong>Methods: </strong>The patient data of newly diagnosed patients aged 80 years or older who underwent radical resection for CRC from 2010 to 2015 were extracted from the Surveillance, Epidemiology, and End Results (SEER) database and then randomly divided into a training cohort and a validation cohort. The patients collected from our hospital were defined as the external validation cohort. Univariate and multivariate Cox regression was used to select independent predictive factors for the construction of a nomogram to predict 1-, 2- and 3-year CSS.</p><p><strong>Results: </strong>The multivariate Cox regression model identified age, T stage, N stage, perineural invasion, chemotherapy, tumour deposits, carcinoembryonic antigen level, number of lymph node metastases, and number of solid organ metastases as independent predictors of survival. The C-index of the nomogram for 1-, 2- and 3-year CSS was 0.758, 0.762, and 0.727, respectively, demonstrating significant clinical value and substantial reliability compared to the TNM stage. The calibration curve and area under the curve also indicated considerable predictive accuracy. In addition, decision curve analysis demonstrated desirable net benefits in clinical application.</p><p><strong>Conclusion: </strong>We constructed a nomogram for predicting the CSS of individual octogenarian patients with CRC who underwent radical resection. The nomogram performed better than the TNM staging system in this particular population and could guide clinicians in clinical follow-up and individual therapeutic plan formulation.</p>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"36 1","pages":"152"},"PeriodicalIF":3.4,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11282125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141764878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between ambient fine particular matter components and subsequent cognitive impairment in community-dwelling older people: a prospective cohort study from eastern China. 社区老年人的环境细微物质成分与认知障碍之间的关系：一项来自中国东部的前瞻性队列研究。

IF 3.4 3区医学

Aging Clinical and Experimental Research Pub Date : 2024-07-26 DOI: 10.1007/s40520-024-02793-9

Tao Zhang, Wenfeng Liu, Tao Yang, Yujia Zhai, Xue Gu, Le Xu, Fudong Li, Mengna Wu, Junfen Lin

{"title":"Association between ambient fine particular matter components and subsequent cognitive impairment in community-dwelling older people: a prospective cohort study from eastern China.","authors":"Tao Zhang, Wenfeng Liu, Tao Yang, Yujia Zhai, Xue Gu, Le Xu, Fudong Li, Mengna Wu, Junfen Lin","doi":"10.1007/s40520-024-02793-9","DOIUrl":"10.1007/s40520-024-02793-9","url":null,"abstract":"<p><strong>Background: </strong>Fine particular matter (PM<sub>2.5</sub>) has been associated with dementia, but limited information is available regarding the association between PM<sub>2.5</sub> components and dementia.</p><p><strong>Aims: </strong>We aimed to identify the major components of PM<sub>2.5</sub> that affect cognitive function to further investigate its mechanism of action, and develop a prevention strategy for dementia.</p><p><strong>Methods: </strong>In this study, we included 7804 participants aged ≥ 60 years recruited from seven counties in Zhejiang province, eastern China. The participants completed the baseline survey between 2014 and 2015, and were followed up until the end of 2020. We adopted single-component robust Poisson regression models for analyses, and estimated relative risks and 95% confidence intervals describing associations between the chemical constituents of PM<sub>2.5</sub> exposure and incident cognitive impairment in those who were free from cognitive impairment at baseline.</p><p><strong>Results: </strong>Significantly positive associations were observed between sulfate, nitrate, ammonium, and organic matter in PM<sub>2.5</sub> and incident cognitive impairment across different exposure periods; the relative risks of 10-year exposure before enrollment ranged from 1.01 to 1.02. However, we did not find a significant association between black carbon and cognitive impairment. The point estimates of the relative risk values did not change substantially after performing the sensitivity analyses.</p><p><strong>Conclusions: </strong>Our findings strengthen the idea that long-term exposure to PM<sub>2.5</sub> mass and its chemical components is associated with an elevated risk of incident cognitive impairment among older adults.</p>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"36 1","pages":"150"},"PeriodicalIF":3.4,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11282123/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141764879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nurse-led medication management as a critical component of transitional care for preventing drug-related problems. 以护士为主导的药物管理是预防药物相关问题的过渡性护理的重要组成部分。

IF 3.4 3区医学

Aging Clinical and Experimental Research Pub Date : 2024-07-26 DOI: 10.1007/s40520-024-02799-3

Yingting Han, Jia Chen, Yulei Xu, Peihua Huang, Lili Hou

{"title":"Nurse-led medication management as a critical component of transitional care for preventing drug-related problems.","authors":"Yingting Han, Jia Chen, Yulei Xu, Peihua Huang, Lili Hou","doi":"10.1007/s40520-024-02799-3","DOIUrl":"10.1007/s40520-024-02799-3","url":null,"abstract":"<p><p>Drug-related problems (DRPs) are critical medical issues during transition from hospital to home with high prevalence. The application of a variety of interventional strategies as part of the transitional care has been studied for preventing DRPs. However, it remains challenging for minimizing DRPs in patients, especially in older adults and those with high risk of medication discrepancies after hospital discharge. In this narrative review, we demonstrated that age, specific medications and polypharmacy, as well as some patient-related and system-related factors all contribute to a higher prevalence of transitional DPRs, most of which could be largely prevented by enhancing nurse-led multidisciplinary medication reconciliation. Nurses' contributions during transitional period for preventing DRPs include information collection and evaluation, communication and education, enhancement of medication adherence, as well as coordination among healthcare professionals. We concluded that nurse-led strategies for medication management can be implemented to prevent or solve DRPs during the high-risk transitional period, and subsequently improve patients' satisfaction and health-related outcomes, prevent the unnecessary loss and waste of medical expenditure and resources, and increase the efficiency of the multidisciplinary teamwork during transitional care.</p>","PeriodicalId":7720,"journal":{"name":"Aging Clinical and Experimental Research","volume":"36 1","pages":"151"},"PeriodicalIF":3.4,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11282160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141764880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0