Giornale italiano di medicina del lavoro最新文献_第6页

[Reference values in biological monitoring of occupational exposure to mutagens and carcinogens]. [职业接触诱变剂和致癌物生物学监测的参考价值]。

Giornale italiano di medicina del lavoro Pub Date : 1994-01-01

E Clonfero, S Pavanello

引用次数: 0

[Multiple occupational exposure to solvents]. [多种职业接触溶剂]。

Giornale italiano di medicina del lavoro Pub Date : 1994-01-01

L Alessio, P Apostoli, M Crippa

引用次数: 0

[Blood interface in environmental and occupational exposure to industrial chemical pollutants]. [环境和职业暴露于工业化学污染物中的血液界面]。

Giornale italiano di medicina del lavoro Pub Date : 1994-01-01

F Brugnone, L Perbellini

{"title":"[Blood interface in environmental and occupational exposure to industrial chemical pollutants].","authors":"F Brugnone, L Perbellini","doi":"","DOIUrl":"","url":null,"abstract":"The concentration of 12 environmental chemical pollutants was measured in the blood of the general population. With reference to the 12 different pollutants, the blood samples tested varied from 88 for acetone to 431 for benzene. Nine of these agents (benzene, toluene, styrene, cumene, xilene, n-hexane, nitrous oxide (N20), acetone and carbon disulphide) were present in all or almost all (100-94%) blood samples. The three chlorides (chloroform, trichloroethylene and tetrachloroethylene) were present only in 60-85% of samples. After acetone and carbon disulphide, with blood concentrations in microgram/l (mean 840 micrograms/l and 2.4 micrograms/l respectively), the highest mean blood levels were those of toluene (1097 ng/l), chloroform (955 ng/l), N2O (915 ng/l), and n-hexane (642 ng/l). Trichloroethylene and free carbon disulphide had similar values (458 and 438 ng/l, respectively). Finally, benzene, styrene and tetrachloroethylene had the lowest values (262, 217 and 149 ng/l, respectively). There was generally a significant difference between rural and urban workers in terms of blood benzene (200 ng/l vs. 264 ng/l), trichloroethylene (180 ng/l vs 763 ng/l) and tetrachloroethylene (62 ng/l vs. 263 ng/l). In a group of subjects potentially exposed to industrial solvents, classed as chemical workers, blood benzene, toluene, chloroform and n-hexane were significantly higher than in rural and urban workers. Smokers showed a significantly higher blood concentration than non-smokers for benzene (381 ng/l vs. 205 ng/l), toluene (1431 ng/l vs. 976 ng/l) and n-hexane (803 ng/l vs. 505 ng/l).","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"16 1-6","pages":"11-7"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19657188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Occupational exposure and individual factors influencing urinary elimination of hippuric acid]. [职业暴露和影响尿中马尿酸消除的个体因素]。

Giornale italiano di medicina del lavoro Pub Date : 1994-01-01

P Bavazzano, A Perico, V Li Donni, A Colzi

引用次数: 0

[Reference values for xenobiotics in biological matrixes: the state of the art]. [生物基质中异种生物制剂的参考值:最新进展]。

Giornale italiano di medicina del lavoro Pub Date : 1994-01-01

P Apostoli

引用次数: 0

[Biological indicators and reference values]. [生物指标及参考值]。

Giornale italiano di medicina del lavoro Pub Date : 1994-01-01

I Franchini, E Bergamaschi

{"title":"[Biological indicators and reference values].","authors":"I Franchini, E Bergamaschi","doi":"","DOIUrl":"","url":null,"abstract":"For biological indicators of exposure, effect or susceptibility, appropriate reference values should be available for a comparative evaluation at individual or at group level. Reference values can be either measured in the same subjects before the exposure starts (internal reference), or extrapolated from an appropriately selected group (external reference). In both cases, confounding factors as well as possible sources of variability (biological and analytical), must be taken into account and controlled. Proceeding from clinical chemistry to occupational and environmental medicine, different exclusion and partition criteria in producing reference values should be adopted. Whereas clinical chemistry is aimed at discriminating people as having or not diseases, preventive medicine deals with healthy subjects to prevent effects derived from abnormal exposure to xenobiotics. To this purpose, it is mandatory that general requirements are satisfied, such as the clear definition of the reference population, the conditions under which the specimens were obtained, the adequacy of the indicator itself to provide information, provided that all laboratory results were produced by adequately standardized methods under sufficient quality control. Since we are shifting from macro to microdoses, reference values would help in discriminating natural or man-made sources of exposure.","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"16 1-6","pages":"5-9"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19656442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Life style as a confounding factor in the study of biological effects of the occupational exposure to chemical substances]. [生活方式作为职业接触化学物质的生物效应研究中的一个混杂因素]。

Giornale italiano di medicina del lavoro Pub Date : 1994-01-01

G Franco, S Bisio

引用次数: 0

[Statistical aspects of the definition of reference values]. [参考值定义的统计方面]。

Giornale italiano di medicina del lavoro Pub Date : 1994-01-01

G Maranelli

{"title":"[Statistical aspects of the definition of reference values].","authors":"G Maranelli","doi":"","DOIUrl":"","url":null,"abstract":"The criteria adopted in the study of reference values have a great influence on the statistical analysis of the data. To avoid a poor statistical treatment of the data, the scope of the study must be well defined: a study to establish reference values for a chemical in the body fluids of a population is not a survey to prove relations among variables and the chemical. In this latter case, criteria to select subjects and methods are different. Confusion between the two types of surveys can lead to poor results. Reference subjects must be selected with precision, using reproducible criteria. It can be suggested to pick-up subjects from a variety of sub-groups of the population. It must be used selection criteria strictly defined to exclude from the study groups of subjects having specified characteristics (patients, resident in contaminated-zone...). The use of partition criteria is useful to know the distribution of some characteristics in the population, or to describe reference values in particular subgroups. On the contrary, partition can not be used to study relationships. Particular attention must be payed in choosing number of strata and variable of partition. When a population is analysed for reference values, the choice of subjects and relevant variables must be made after consulting a statistician.","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"16 1-6","pages":"31-6"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19656438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The diagnosis of occupational hand-arm syndromes. 2. The quantification of the plethysmographic changes due to the cold test]. 职业性手臂综合征的诊断。2. 因冷试验而引起的体积脉搏变化的定量分析。

Giornale italiano di medicina del lavoro Pub Date : 1993-09-01

A Taccola, M Perotti, F Scafa

引用次数: 0

[The echographic diagnosis of neurogenic paraosteoarthropathies in myelosis patients]. [脊髓症患者神经源性骨旁关节病的超声诊断]。

Giornale italiano di medicina del lavoro Pub Date : 1993-09-01

C Pistarini, S Carlevati, A Contardi

{"title":"[The echographic diagnosis of neurogenic paraosteoarthropathies in myelosis patients].","authors":"C Pistarini, S Carlevati, A Contardi","doi":"","DOIUrl":"","url":null,"abstract":"To assess the role of the ultrasonic imaging evaluation of articular lesions suspected to be the initial presentation of heterotopic ossifications (HO) 59 consecutive spinal cord injured patients were studied. 32 out of 59 patients showed clinical signs of local inflammation in one of the articular sites of the upper or lower limbs, sonographic scans proved to be diagnostic of HO in 7 out of those 32 patients before a their radiographic findings. Serial sonographic examinations were performed utilising a 7.5 MegaHertz transducer probe for 2 months. The imaging abnormalities were correlated with biochemical levels of serum alkaline phosphatase, modifications of radiographic features and bone 99mTC scintigraphy. Scintigraphy revealed to have a high sensitivity but a low specificity for the diagnosis of HO. Also the serum levels of alkaline phosphatase was not a sensitive indicator of early HO in our group of patients. Moreover serial sonographic scans confidently excluded the HO in the 25 patients with no initial signs of the disease without any false negative results. Thus, early sonographic assessment of patients with spinal cord injury in which local signs of inflammation suggest initial HO formation revealed to be superior to the other utilized technique for the diagnosis of HO and may be considered a valuable alternative in particular to evaluate the evolutive pattern of this disease.","PeriodicalId":77147,"journal":{"name":"Giornale italiano di medicina del lavoro","volume":"15 5-6","pages":"159-63"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18619429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0