[The echographic diagnosis of neurogenic paraosteoarthropathies in myelosis patients].

C Pistarini, S Carlevati, A Contardi
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Abstract

To assess the role of the ultrasonic imaging evaluation of articular lesions suspected to be the initial presentation of heterotopic ossifications (HO) 59 consecutive spinal cord injured patients were studied. 32 out of 59 patients showed clinical signs of local inflammation in one of the articular sites of the upper or lower limbs, sonographic scans proved to be diagnostic of HO in 7 out of those 32 patients before a their radiographic findings. Serial sonographic examinations were performed utilising a 7.5 MegaHertz transducer probe for 2 months. The imaging abnormalities were correlated with biochemical levels of serum alkaline phosphatase, modifications of radiographic features and bone 99mTC scintigraphy. Scintigraphy revealed to have a high sensitivity but a low specificity for the diagnosis of HO. Also the serum levels of alkaline phosphatase was not a sensitive indicator of early HO in our group of patients. Moreover serial sonographic scans confidently excluded the HO in the 25 patients with no initial signs of the disease without any false negative results. Thus, early sonographic assessment of patients with spinal cord injury in which local signs of inflammation suggest initial HO formation revealed to be superior to the other utilized technique for the diagnosis of HO and may be considered a valuable alternative in particular to evaluate the evolutive pattern of this disease.

[脊髓症患者神经源性骨旁关节病的超声诊断]。
为了评估超声成像对疑似异位骨化(HO)首发表现的关节病变的评估作用,我们对59例连续脊髓损伤患者进行了研究。59例患者中有32例表现出上肢或下肢某一关节部位局部炎症的临床症状,其中7例在x线检查前被证实为HO。使用7.5兆赫换能器探头进行连续超声检查2个月。影像学异常与血清碱性磷酸酶生化水平、影像学特征改变及骨99mTC显像相关。显像对HO的诊断敏感性高,特异性低。在本组患者中,血清碱性磷酸酶水平也不是早期HO的敏感指标。此外,连续超声扫描在25例没有疾病初始体征且无假阴性结果的患者中自信地排除了HO。因此,在局部炎症迹象提示初始HO形成的脊髓损伤患者中,早期超声评估显示优于其他用于诊断HO的技术,并且可能被认为是一种有价值的替代方法,特别是评估这种疾病的进化模式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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