Al-Azhar Assiut Medical Journal最新文献_第4页

Seroprevelance of cytomegalovirus in healthy blood donors in Kafr El Sheikh General Hospital Kafr El Sheikh总医院健康献血者巨细胞病毒血清检测

Al-Azhar Assiut Medical Journal Pub Date : 2022-04-01 DOI: 10.4103/azmj.azmj_3_22

A. El Mallah, M. Afify, Mohammed Abdel-Halim, Amr Mohammed

{"title":"Seroprevelance of cytomegalovirus in healthy blood donors in Kafr El Sheikh General Hospital","authors":"A. El Mallah, M. Afify, Mohammed Abdel-Halim, Amr Mohammed","doi":"10.4103/azmj.azmj_3_22","DOIUrl":"https://doi.org/10.4103/azmj.azmj_3_22","url":null,"abstract":"Background and aim Cytomegalovirus (CMV) transmission to seronegative patients with inadequate immunity might result in significant consequences. The goal of the study was to determine the prevalence of CMV antibodies in healthy blood donors at the Kafr El Sheikh General Hospital. Patients and methods This research enrolled 100patients with the same inclusion and exclusion criteria, in age ranging between 18 and 60 years, with confirmed seronegativity for hepatitis C virus, hepatitis B virus, and HIV. All patients were asked to complete history taking, full clinical examination, laboratory assessment, and peripheral blood samples. The blood samples were taken from each individual to test for CMV immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies. Another sample was taken from IgM-positive cases in order to do PCR testing for CMV DNA. Results All cases among the study group were showing a positive CMV IgG with a high rate up to (100%). Consequently, in the general hospital in Kafr El Sheikh, healthy blood donors had a significant prevalence of CMV IgG. While, there were three (3%) patients of them had positive CMV IgM and 97 (97%) patients of them had Negative CMV IgM, this indicates a rarity of CMV IgM in healthy blood donors at Kafr El Sheikh General Hospital. Conclusion The high seroprevelance of CMV is a barrier to developing blood products of seronegative CMV in blood banks; nonetheless, we found that concentrated screening of a specific group of blood donors would be the best way to achieve this goal.","PeriodicalId":7711,"journal":{"name":"Al-Azhar Assiut Medical Journal","volume":"20 1","pages":"203 - 210"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43261558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endovascular evaluation of intracranial atherosclerotic stenosis in a sample of Egyptian patients presented with ischemic stroke 埃及缺血性脑卒中患者颅内动脉粥样硬化狭窄的血管内评价

Al-Azhar Assiut Medical Journal Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_75_21

M. Hassan, Khalid Sobh, M. Galal, Salah Ahmed, Sherief Al shazly, A. Shokry

{"title":"Endovascular evaluation of intracranial atherosclerotic stenosis in a sample of Egyptian patients presented with ischemic stroke","authors":"M. Hassan, Khalid Sobh, M. Galal, Salah Ahmed, Sherief Al shazly, A. Shokry","doi":"10.4103/azmj.azmj_75_21","DOIUrl":"https://doi.org/10.4103/azmj.azmj_75_21","url":null,"abstract":"Background and aim Intracranial atherosclerosis is an important etiology of ischemic stroke and is associated with multiple vascular risk factors. Endovascular evaluation is used for assessing patterns and distributions of intracranial atherosclerotic stenosis in a sample of Egyptian patients presented with ischemic stroke. Patients and methods A total of 50 patients with ischemic stroke or transient ischemic attack were included. Assessment of the state of cerebral vessels before the procedure was done by duplex ultrasound, magnetic resonance angiography, and/or computed tomography angiography to confirm any stenosis in intracranial vessels. Neurological assessment was done before and after the procedure using the National Institutes of Health Stroke Scale score. Digital subtraction angiography was done to evaluate the degrees and patterns of stenosis. Results A total of 50 participants (29 males and 21 females) were included. Their ages ranged from 30 to 78 years. The major risk factors were dyslipidemia (62.0%), hypertension (60.0%), diabetes mellitus (54.0%), smoking (48.0%), and atrial fibrillation (22.0%). The procedure was performed on 50 patients. A total of 39 (78.0%) patients had angiographic findings of vessel stenosis in either extracranial or intracranial vessels or both. In those 39 patients, 32 (64.0%) patients had arterial stenosis, and seven (14.0%) patients were found to have total occlusion. A total of 18 (36.0%) patients had angiographic findings of intracranial atherosclerotic stenosis. Of these 18 patients, 14 (28.0%) patients had arterial stenosis, and four (8.0%) patients were found to have total occlusion. The most common site of intracranial stenosis was middle cerebral artery (33.3%). Conclusion Endovascular evaluation of patients with ischemic stroke is yielding, informative, safe, and easy to be done.","PeriodicalId":7711,"journal":{"name":"Al-Azhar Assiut Medical Journal","volume":"20 1","pages":"85 - 92"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49349693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Value of multislice computed tomography-coronary angiography in predicting coronary artery diseases in type-2 diabetic patients in the chest pain unit 多层计算机断层扫描冠状动脉造影在预测胸痛病房2型糖尿病患者冠状动脉疾病中的价值

Al-Azhar Assiut Medical Journal Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_47_21

Ragab Ali Habour, I. Shawki, Ibrahim Faragallah, hossam Al-Adl

{"title":"Value of multislice computed tomography-coronary angiography in predicting coronary artery diseases in type-2 diabetic patients in the chest pain unit","authors":"Ragab Ali Habour, I. Shawki, Ibrahim Faragallah, hossam Al-Adl","doi":"10.4103/azmj.azmj_47_21","DOIUrl":"https://doi.org/10.4103/azmj.azmj_47_21","url":null,"abstract":"Background and aim Diabetes mellitus is a metabolic disorder affecting a wide range of the population all over the world. Microvascular and macrovascular complications are very common in diabetic patients with high incidence of affection of the coronary arteries. Rapid and efficient management in cases (especially diabetics) complaining of chest pain at the emergency department is a matter of great importance to decrease the incidence of subsequent complications. Our aim was to predict coronary artery diseases in type-2 diabetic patients with typical chest pain with normal initial cardiac investigations at the emergency room by using computed tomography (CT) coronary angiography. Patients and methods A total number of 100 patients were included in this study and classified into two groups: 80 patients with diabetes mellitus (group A) and 20 nondiabetic patients (group B) presented with chest pain. Complete history was taken from the cases with performing of complete physical examination, and routine laboratory and radiological investigations. Additionally, echocardiography and multislice CT-coronary angiography (coronary computed tomography angiography) were done for all cases. Also, calcium score was calculated. Results CT angiography revealed affection in 19 (23.8%) cases of the cases in group A with no affected cases in group B with a statistically significant difference between the two groups. There was a high statistically significant agreement between the findings of the CT angiography and coronary angiography results (P<0.001). CT angiography had sensitivity of 70.37%, specificity of 100%, positive predictive value 100%, negative predictive value 86.89%, and accuracy of 90%. Conclusion An early coronary computed tomography angiography strategy has revealed high sensitivity in prediction of coronary artery disease affection as compared with ordinary coronary angiography in cases presented with chest pain to emergency department.","PeriodicalId":7711,"journal":{"name":"Al-Azhar Assiut Medical Journal","volume":"20 1","pages":"46 - 53"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43327642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison between video head impulse and videonystagmography in patients with vertiginous migraine 眩晕性偏头痛患者的视频头脉冲与视频震动图的比较

Al-Azhar Assiut Medical Journal Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_147_21

W. Mohamed, Gehan Elzaree, Mahmoud Hassan, A. Mohamed

{"title":"Comparison between video head impulse and videonystagmography in patients with vertiginous migraine","authors":"W. Mohamed, Gehan Elzaree, Mahmoud Hassan, A. Mohamed","doi":"10.4103/azmj.azmj_147_21","DOIUrl":"https://doi.org/10.4103/azmj.azmj_147_21","url":null,"abstract":"Background and aim In addition to the classic migraine symptoms of vertigo, dizziness, and imbalance, vestibular migraine causes vertigo, dizziness, and imbalance. The video head impulse test (VHIT) is a novel approach for determining the function of each semicircular canal. Although videonystagmography (VNG) is an effective tool for identifying peripheral vertigo, not all patients with central vertigo can be easily detected. The goal of this research is to confirm the findings of the functional outcome of VHIT versus VNG in patients with vertiginous migraine. Patients and methods We selected 40 patients (both sexes) with vestibular migraine and 25 normal individuals as control. Both groups were subjected to complete clinical examination after thorough history taking, laboratory investigations, VHIT, and VNG. Results VNG had excellent predictive value in the patients’ group (95% confidence interval=0.891–0.998, P=0.0001) with a 96.6% sensitivity and 86.2% specificity, while VHIT had poor predictive value with a sensitivity of 100% and specificity of 48.1% (95% confidence interval=0.523–0.779, P=0.099). Conclusion VNG has a specificity and sensitivity for the prognosis of vestibular migraine that is virtually identical to VHIT.","PeriodicalId":7711,"journal":{"name":"Al-Azhar Assiut Medical Journal","volume":"20 1","pages":"154 - 157"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42062060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Blood monocyte subtypes in patients with pulmonary tuberculosis infection 肺结核感染患者血单核细胞亚型

Al-Azhar Assiut Medical Journal Pub Date : 2022-01-01 DOI: 10.4103/AZMJ.AZMJ_142_20

Tamer El-Rab Attia, M. Abdelmeguid, A. Mohammed, Hamada Fayed

{"title":"Blood monocyte subtypes in patients with pulmonary tuberculosis infection","authors":"Tamer El-Rab Attia, M. Abdelmeguid, A. Mohammed, Hamada Fayed","doi":"10.4103/AZMJ.AZMJ_142_20","DOIUrl":"https://doi.org/10.4103/AZMJ.AZMJ_142_20","url":null,"abstract":"Background and aim Monocytes are the primary target for Mycobacterium tuberculosis infection. Important alterations in the proportions of circulating monocyte subpopulations were found in patients with active tuberculosis (aTB). Our aim was to investigate the peripheral blood monocyte subsets in patients with active pulmonary tuberculosis (aPTB) and to evaluate their role in treatment response. Patients and methods A case–control study included 30 patients with aPTB and 30 healthy controls. Laboratory investigations include sputum examination, tuberculin test, and nucleic acid amplification test using GeneXpert MTB/RIF assay on sputum sample for patients only to confirm the diagnosis of aPTB. For all participants; complete blood count, erythrocyte-sedimentation rate, HIV antibodies, and flow cytometry analysis of peripheral blood monocyte subsets were done using surface markers CD14 phycoerythrin cyanin 7 and CD16 fluoroisothiocyanate for identification of monocyte subsets. Flow cytometry analysis was repeated 2 months after the start of treatment in aTB patients only. Results Classical monocytes were decreased while intermediate, and nonclassical monocytes were increased in aTB patients before treatment more than after 2 months of treatment and control group (P≤0.0001 for each). There was no significant difference in the three monocyte subsets between PTB patients after treatment and healthy controls. Also, the classical monocytes decreased while intermediate, and nonclassical monocytes increased in aTB patients with positive tuberculin test more than healthy controls with positive tuberculin test (P<0.0001 for each). Conclusion The expansion of CD16+ monocytes was reversed after treatment with anti-TB drugs and could be used to follow up tuberculous patients for treatment effectiveness.","PeriodicalId":7711,"journal":{"name":"Al-Azhar Assiut Medical Journal","volume":"20 1","pages":"39 - 45"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41595959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

T-helper and natural killer cells’ disturbance in active alopecia areata 活动性斑秃患者辅助T细胞和自然杀伤细胞的紊乱

Al-Azhar Assiut Medical Journal Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_76_21

A. Younes, Refaat Hammad, Ali Sobhy

{"title":"T-helper and natural killer cells’ disturbance in active alopecia areata","authors":"A. Younes, Refaat Hammad, Ali Sobhy","doi":"10.4103/azmj.azmj_76_21","DOIUrl":"https://doi.org/10.4103/azmj.azmj_76_21","url":null,"abstract":"Background and aim Alopecia areata (AA) is a common nonscarring hair disease targeting the hair follicles during the anagen phase, leading to hair loss. The etiology of AA is still unclear; however, evidence revealed the association of this disease with immune disturbance. Therefore, we aimed in this study to evaluate the level of natural killer (NK) and T-helper 1 (Th1) cells in the peripheral circulation of patients with different subtypes of AA during the active stage in comparison with the controls. Patients and methods Venous blood samples from 50 female patients and 50 healthy-controls were collected to evaluate the level of Th1 and NK cells using flow cytometry. Results Patients with active patchy AA, alopecia totalis, and alopecia universalis were associated with a lower level of circulating Th1 and NK cells when compared with the controls. Conclusion The observed reduction in the circulating Th1 and NK cells indicates the autoimmune nature of the disease. Also, we highlight the cellular shift from the peripheral circulation to the lesion site during the active stage; however, more research is required to reveal the exact mechanism for this phenomenon.","PeriodicalId":7711,"journal":{"name":"Al-Azhar Assiut Medical Journal","volume":"20 1","pages":"54 - 59"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43748879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression of matrix metalloproteinase-2 and survivin in pancreatic carcinoma: an immunohistochemical study 胰腺癌中基质金属蛋白酶-2和survivin表达的免疫组化研究

Al-Azhar Assiut Medical Journal Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_106_21

Said Mohamed, Yasser Eldowik

引用次数: 0

Short-term effects of prophylactic intravitreal injection of triamcinolone and moxifloxacin combination after cataract surgery 白内障术后预防性玻璃体内注射曲安奈德与莫西沙星的近期疗效

Al-Azhar Assiut Medical Journal Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_1_22

E. Saliem

引用次数: 0

Comparative study between the closure of small-sized and medium-sized urethral cutaneous fistula after hypospadias repair with and without autologous platelet-rich plasma graft 自体富血小板血浆移植与非自体富血小板血浆移植修复尿道下裂后小、中型尿道皮瘘闭合的比较研究

Al-Azhar Assiut Medical Journal Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_145_21

A. Kopeya, A. Elshamy, Mahmoud S Moussa

引用次数: 0

Association between the inflammatory biomarker YKL-40 (chitinase-3-like 1) in type-2 diabetic patients and ischemic heart diseases 2型糖尿病患者炎症生物标志物YKL-40(几丁质酶-3样1)与缺血性心脏病的关系

Al-Azhar Assiut Medical Journal Pub Date : 2022-01-01 DOI: 10.4103/azmj.azmj_157_20

AishaH.T.M Abdelhafez, ZainabA El Shawaf, MervatA Abbas, M. El-Kader, E. Ibrahim

引用次数: 0