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American journal of physiologic imaging最新文献

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Delayed reflow of an ischemic infarct after spontaneous thrombolysis studied by CBF tomography using SPECT and Tc-99m HMPAO. 采用SPECT和Tc-99m HMPAO的CBF断层扫描研究自发性溶栓后缺血性梗死的延迟再流。
American journal of physiologic imaging Pub Date : 1991-10-01
J M Companioni, N A Lassen, P Tfelt-Hansen, L Friberg
{"title":"Delayed reflow of an ischemic infarct after spontaneous thrombolysis studied by CBF tomography using SPECT and Tc-99m HMPAO.","authors":"J M Companioni,&nbsp;N A Lassen,&nbsp;P Tfelt-Hansen,&nbsp;L Friberg","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A patient with a large ischemic infarct in the left middle cerebral artery territory was studied six times in the acute/subacute phase by cerebral blood flow (CBF) tomography using Tc-99m-HMPAO. The SPECT instrument used was a brain dedicated highly sensitive four-camera system (TOMOMATIC 232) that allows to keep the radioactivity dose per study at 10 mCi (370 MBq). Transcranial Doppler and angiography showed spontaneous disappearance of the middle cerebral artery occlusion between days 5 and 8, while CBF showed reperfusion of the borderzone with flow increasing over several days after resolution of the occlusion with flows reaching levels above that of the opposite non-affected side (\"Luxury Perfusion\"). The delayed reflow implies, that SPECT may not constitute a reliable tool for evaluating the success or failure of thrombolytic treatment in ischemic stroke.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"6 4","pages":"167-71"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12979181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation of the T4/5 left ventricular functional image on a VAX-based Lexidata image processing station. 在基于vax的Lexidata图像处理站上实现T4/5左心室功能图像。
American journal of physiologic imaging Pub Date : 1991-10-01
K Kouris, K Al-Ali, I M Hassan, H M Abdel-Dayem
{"title":"Implementation of the T4/5 left ventricular functional image on a VAX-based Lexidata image processing station.","authors":"K Kouris,&nbsp;K Al-Ali,&nbsp;I M Hassan,&nbsp;H M Abdel-Dayem","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A VAX-based Lexidata image processing station has been used for the development and application of image processing and data analysis techniques in nuclear medicine. Within the area of cardiac multigated equilibrium blood-pool scintigraphy, the computational implementation of the T4/5 functional image, a new left ventricular functional image, is presented. This image reflects myocardial compliance. The versatility of the implementation is demonstrated. Examples of the T4/5 functional image are presented. The VAX-based Lexidata image processing station is a useful tool for parameter, feature, and image extraction from nuclear medicine images.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"6 4","pages":"183-9"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12979187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Common bile duct obstruction in cystic fibrosis: utility of hepatobiliary scintigraphy. 囊性纤维化中胆总管梗阻:肝胆造影的应用。
American journal of physiologic imaging Pub Date : 1991-10-01
L M Fig, D Daugherty, T Nostrant, B Shapiro
{"title":"Common bile duct obstruction in cystic fibrosis: utility of hepatobiliary scintigraphy.","authors":"L M Fig,&nbsp;D Daugherty,&nbsp;T Nostrant,&nbsp;B Shapiro","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Abdominal pain occurs commonly in patients with cystic fibrosis, and is the result of a variety of causes, including hepatobiliary disorders. With the increasing duration of survival in these patients, diagnostic investigations for abdominal pain, including hepatobiliary scanning, may be utilized more frequently than in the past. Difficulties in the interpretation of scintigraphic studies may arise because of associated gallbladder anomalies that occur in more than 50% of patients with cystic fibrosis. Hypoplasia of the gallbladder (microgallbladder) occurs commonly. A case is presented in which Tc-99m disofenin hepatobiliary scanning proved diagnostic in a patient with cystic fibrosis and cholelithiasis leading to common bile duct obstruction. The hepatobiliary abnormalities and causes of common bile duct obstruction encountered in cystic fibrosis are reviewed.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"6 4","pages":"194-6"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12979188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Change of cerebral glucose metabolism by antineoplastic drug. 抗肿瘤药物对脑糖代谢的影响。
American journal of physiologic imaging Pub Date : 1991-10-01
J Okada, K Yoshikawa, K Imazeki, K Uno, S Minoshima, J Itami, H Maruno, J Kuyama, N Arimizu
{"title":"Change of cerebral glucose metabolism by antineoplastic drug.","authors":"J Okada,&nbsp;K Yoshikawa,&nbsp;K Imazeki,&nbsp;K Uno,&nbsp;S Minoshima,&nbsp;J Itami,&nbsp;H Maruno,&nbsp;J Kuyama,&nbsp;N Arimizu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To estimate change of cerebral glucose metabolism by anticancer drugs, positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) was performed in 11 patients with malignancies who did not show neurological symptoms. In a patient treated with intravenous high-dose methotrexate (HD-MTX) and intrathecal MTX, apparent decrease of glucose metabolism was observed. HD-MTX and intrathecal MTX may cause cerebral glucose metabolism disorder primarily. Cerebral glucose metabolism was also mildly reduced by chemotherapy with drugs other than MTX and by radiotherapy outside the brain, with a corresponding change of blood data. It may reflect a psychosomatic change in whole body.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"6 4","pages":"162-6"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12890244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thiol reduction-mediated 99mTc-IgG for scintigraphy of inflammatory lesions in the baboon model. 巯基还原介导的99mTc-IgG用于狒狒模型炎症病变的显像。
American journal of physiologic imaging Pub Date : 1991-10-01
I C Dormehl, W K Louw, N Hugo, I F Redelinghuys, P J Fourie
{"title":"Thiol reduction-mediated 99mTc-IgG for scintigraphy of inflammatory lesions in the baboon model.","authors":"I C Dormehl,&nbsp;W K Louw,&nbsp;N Hugo,&nbsp;I F Redelinghuys,&nbsp;P J Fourie","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Radiolabeling procedures may modify the structure of the Fc portion of the immunoglobulin molecule in such a way that its in vivo immunological behavior may be altered and its efficacy as radiopharmaceutical for inflammatory lesions impaired. This study tested the efficacy of thiol reduction-mediated 99mTc human IgG for scintigraphy of focal inflammatory lesions, either bacterially or chemically induced and located either in the abdominal/thoracical region or in the thigh of baboons. Positive images were obtained in the thigh lesions between 4 and 7 hr after i.v. administration of the labeled IgG. The abdominal/thoracic lesions were never very clear, mostly because of very hot kidneys. Late visualization (20 hr) of all lesions was poor and a high background was present. Bacterially induced lesions were better visible, although no neutrophil nor monocyte activity could be established in the mechanism of the IgG localization.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"6 4","pages":"176-82"},"PeriodicalIF":0.0,"publicationDate":"1991-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12979186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The diagnostic value of immediate post-exercise left ventricular ejection fraction (LVEF). 运动后立即左室射血分数(LVEF)的诊断价值。
American journal of physiologic imaging Pub Date : 1991-07-01
F H Jansen, M J van Kroonenburgh, E E van der Wall, R Valkema, A H Zwinderman, J A Blokland, E K Pauwels
{"title":"The diagnostic value of immediate post-exercise left ventricular ejection fraction (LVEF).","authors":"F H Jansen,&nbsp;M J van Kroonenburgh,&nbsp;E E van der Wall,&nbsp;R Valkema,&nbsp;A H Zwinderman,&nbsp;J A Blokland,&nbsp;E K Pauwels","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The diagnostic value of immediate post-exercise left ventricular ejection fraction (LVEF) was assessed in 161 patients at rest, during maximal exercise, and immediately post-exercise by radionuclide angiography. Fifteen patients had a second examination, giving a total of 176 radionuclide examinations. Additionally, the correlation between post-exercise LVEF and physical validity was investigated. Sixty-one patients (35%) with a recent myocardial infarction (less than 4 weeks), 66 patients (37%) with an old myocardial infarction (greater than 4 weeks), and 21 patients (12%) with valvular lesions were studied. Twenty-eight patients (16%) with an abdominal aneurysm were considered as controls based on history and a normal resting and exercise electrocardiogram (ECG). LVEF and a cumulative regional wall motion (RWM) score for three regions were obtained. LVEF post-exercise was significantly increased compared to LVEF at maximal exercise in all four diagnostic groups. Absolute LVEF values were significantly dependent on the level of exercise. We conclude that immediate post-exercise LVEF should not be used for separating patients with and without coronary artery disease.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"6 3","pages":"105-9"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12935220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prostaglandin E1 and papaverine: a comparative study on the ability to increase the penile bloodpool as measured by the 99mTc-penogram in the baboon model. 前列腺素E1和罂粟碱:在狒狒模型中通过99mTc-penogram测量增加阴茎血池的能力的比较研究。
American journal of physiologic imaging Pub Date : 1991-07-01
D De Bruin, I C Dormehl, D J Du Plessis, L Jacobs, N Hugo, M Maree
{"title":"Prostaglandin E1 and papaverine: a comparative study on the ability to increase the penile bloodpool as measured by the 99mTc-penogram in the baboon model.","authors":"D De Bruin,&nbsp;I C Dormehl,&nbsp;D J Du Plessis,&nbsp;L Jacobs,&nbsp;N Hugo,&nbsp;M Maree","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The evaluation of arterial blood supply and venous drainage of the penis is essential in assessing the impotent male. The vaso-active drugs prostaglandin E1 and papaverine, as intracavernous injections, cause penile erections in humans by influencing the arterial blood supply and venous drainage. These drugs were used in the normal baboon and in vascular compromised baboons using a 99mTc-penogram to quantify the vascular status of the penis. Ligation of the A. Iliaca Interna was performed to change the penile blood supply, thus compromising the vascular supply. It was observed that pre- and post-operatively, the increase in the penile bloodpool was more dramatic although not significantly so (P less than 0.05), but more variable after papaverine than with prostaglandin E1. The effect was even more enhanced (P less than 0.05) in the vascular compromised baboons so that the occurrence of priapism after papaverine can speculatively not be excluded. Also the more consistent vasoactive response after prostaglandin E1 seems to establish it as the superior intracavernous injectable agent.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"6 3","pages":"129-32"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12936455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Animal tumor models for the evaluation of in-vivo diagnostic radiotracers. 评估体内诊断性放射性示踪剂的动物肿瘤模型。
American journal of physiologic imaging Pub Date : 1991-07-01
L I Wiebe, J Allalunis-Turner, A Franko, A Kanclerz
{"title":"Animal tumor models for the evaluation of in-vivo diagnostic radiotracers.","authors":"L I Wiebe,&nbsp;J Allalunis-Turner,&nbsp;A Franko,&nbsp;A Kanclerz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"6 3","pages":"133-49"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12936464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The value of parenchymal transit time index of Tc-99m DTPA diuretic renography in the evaluation of surgery in chronic bilharzial obstructive uropathy. Tc-99m DTPA利尿肾造影实质传递时间指数在慢性双颌梗阻性尿病手术评价中的价值。
American journal of physiologic imaging Pub Date : 1991-07-01
R H Bahar, K Kouris, M Sabha, F M Abu Zidan, M Awdeh, H M Abdel-Dayem
{"title":"The value of parenchymal transit time index of Tc-99m DTPA diuretic renography in the evaluation of surgery in chronic bilharzial obstructive uropathy.","authors":"R H Bahar,&nbsp;K Kouris,&nbsp;M Sabha,&nbsp;F M Abu Zidan,&nbsp;M Awdeh,&nbsp;H M Abdel-Dayem","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Selection of patients with chronic bilharzial uropathy (CBU) for surgery is a difficult problem due to the presence of grossly dilated urinary tracts without a significant obstruction in most of the cases. In this prospective study of 40 patients with CBU, the time-activity curve (TAC) patterns of the pre- and postoperative Tc-99m DTPA diuretic renography (RDR) studies were compared with the corresponding parenchymal transit time indices (PTTI). The aims were to find out which of these renographic parameters was more accurate in identifying obstruction and which was better in predicting the outcome of surgery. PTTI was more sensitive than TAC in identifying obstruction (96% and 92%, respectively) but it was less specific (78% and 98%). The detection accuracy of RDR for obstruction using TAC patterns was 96% compared to 84% using PTTI. Being independent of renal uptake function, PTTI could not predict the outcome of surgery as TAC could. In contrast to PTTI, TAC patterns could differentiate obstructed kidneys from severely nephropathic kidneys. However, PTTI was useful in identifying kidneys with residual nephropathy.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"6 3","pages":"121-8"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12936457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measurements of the effect of dipyridamole on regional myocardial blood flow with positron emission tomography and the first-pass flow model. 用正电子发射断层扫描和首过血流模型测量双嘧达莫对局部心肌血流的影响。
American journal of physiologic imaging Pub Date : 1991-07-01
T Himi, M Endo, K Yoshida, A Kagaya, Y Masuda, Y Inagaki, H Fukuda, T Iinuma, T Yamasaki, N Fukuda
{"title":"Measurements of the effect of dipyridamole on regional myocardial blood flow with positron emission tomography and the first-pass flow model.","authors":"T Himi,&nbsp;M Endo,&nbsp;K Yoshida,&nbsp;A Kagaya,&nbsp;Y Masuda,&nbsp;Y Inagaki,&nbsp;H Fukuda,&nbsp;T Iinuma,&nbsp;T Yamasaki,&nbsp;N Fukuda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We assessed percent changes of regional myocardial blood flow (RMBF) after infusion of dipyridamole (0.56 mg/kg) with dynamic N-13 ammonia PET and the first-pass flow model. Positron emission tomography (PET) was performed at rest and after infusion of dipyridamole in 17 participants [five normal subjects, five patients with hypertrophic cardiomyopathy (HCM), and seven patients with coronary artery disease]. Dipyridamole increased RMBF 126 +/- 69% (mean +/- SD) in normal subjects and 55 +/- 43% in the patients with HCM. In the cases of coronary artery disease, the percent changes of RMBF were +19 +/- 19% in ischemic areas and +76 +/- 23% in nonischemic areas. These results demonstrate that N-13 ammonia dynamic PET study is useful in assessing the percent changes of RMBF induced by dipyridamole infusion.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"6 3","pages":"110-5"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12936452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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