A H Elgazzar, M Fernandez-Ulloa, J R Ryan, R McDevitt, S A Daya, H R Maxon
{"title":"Scintigraphic evaluation of duodenogastric reflux: significance in the diagnosis of acute cholecystitis.","authors":"A H Elgazzar, M Fernandez-Ulloa, J R Ryan, R McDevitt, S A Daya, H R Maxon","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Duodenogastric reflux (DGR) as seen on hepatobiliary scintigraphy has been reported as a useful secondary sign for the diagnosis of acute cholecystitis. We evaluated the association of reflux with cases of acute cholecystitis as compared to those with chronic cholecystitis or other conditions. Thirty-six of 198 patients referred for hepatobiliary imaging showed DGR (18%). Among 26 patients with acute cholecystitis, 6 (23%) had DGR as compared to 9/40 (23%) cases with chronic cholecystitis, 3/12 cases with acute pancreatitis, 4/13 cases with previous cholecystectomy, and 3/8 cases with duodenal ulcer. No statistically significant differences were found between the prevalence of DGR in cases with acute cholecystitis and those with chronic cholecystitis or other nonacute cholecystitis diagnostic categories. Although acute cholecystitis is a condition frequently associated with DGR, such reflux is a nonspecific finding and should not be considered as a secondary sign of acute cholecystitis when interpreting hepatobiliary scans.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"7 3-4","pages":"239-41"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12516064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Magnetic resonance imaging of brain function.","authors":"R Turner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>New techniques for imaging of brain function are described, which utilize magnetic resonance imaging. Echo-planar imaging (EPI), the preferred method, is introduced and technical issues are discussed. Two recent approaches for measurement of blood flow are explained: contrast agent bolus tracking and black blood perfusion. An intrinsic contrast technique, which utilizes the paramagnetism of deoxyhemoglobin, is presented. Results from experiments on functional imaging of the human brain are shown, and the specific advantages of MRI for this purpose are discussed.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"7 3-4","pages":"136-45"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12516883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in contrast echocardiography: intraoperative perfusion assessment.","authors":"S B Feinstein, S Aronson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Contrast ultrasound techniques provide on-line assessments of regional tissue perfusion. Intraoperative clinical studies of cardiac revascularization and renal transplantation have been performed and are currently under active clinical investigation. The potential to diagnose and manage patients through the use of contrast ultrasound techniques is just beginning to be realized. With continued development of the contrast agents and improved computer-aided software analyses programs, the future of the real-time perfusion imaging looks bright.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"7 3-4","pages":"155-9"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12516885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Computed tomography with monochromatic x rays.","authors":"F A Dilmanian","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recent advances in the development of synchrotron facilities that provide high-energy and high-flux x-ray beams allow the use of monochromatic x rays at a < 0.5% energy bandwidth (i.e. energy width of < 500 eV at 100 keV) for computed tomography (CT) of humans. Such CT systems will consist of a fixed, horizontal, low-divergence fan beam and a seated subject rotating about a vertical axis. Compared to conventional CT, the new system should significantly improve contrast resolution of the image and provide better image quantification because of its lack of beam-hardening effects and its efficient implementation of energy-selective imaging methods such as dual-photon absorptiometry and K-edge subtraction with high-atomic-number (high-Z) contrast-enhancement elements. Further, the nearly parallel synchrotron x-ray beam geometry minimizes patient-to-detector scattering when the detector is positioned far from the patient. The design considerations and the expected performance of monochromatic CT are described, in particular those of the CT being developed at the National Synchrotron Light Source. The potential applications of the method in neuroradiology, cardiac and vascular imaging, bone densitometry, lung imaging, and radiotherapy are discussed. The future of monochromatic CT in research and in clinical diagnostics is also reviewed, as are the prospects for development of compact sources of x rays with narrow-energy bandwidths.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"7 3-4","pages":"175-93"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12516887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge-based multi-modality three-dimensional image analysis of the brain.","authors":"A P Dhawan, L Arata","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>With the recent advances in medical imaging, three-dimensional anatomical and metabolic images of the brain are now available through MR/CT and PET/SPECT imaging modalities. Computerized multi-modality three-dimensional brain image registration and analysis can provide important correlated information for improving diagnosis and studying the pathology of disease. Such analysis may also provide help in planning brain surgery. Further, an anatomical model based quantification and analysis of internal structure can be used to develop a computerized anatomical atlas. Conventional anatomical atlases provide rigid spatial distribution of internal structures extracted from a single subject. The proposed computerized anatomical atlas provides probabilistic spatial distributions which can be easily updated to incorporate the variability of brain structures of subjects selected from pre-defined groups. This paper first presents a review of the current trends in knowledge-based segmentation, labeling, and analysis of MR brain images and then describes the Principal Axes Transformation based registration of three-dimensional MR brain images to develop composite models of selected internal brain structures. The composite models can be used as a computerized anatomical atlas in model-based segmentation and labeling of MR brain images. Three-dimensional labeled MR images of the brain can also be registered and correlated with PET images for analyzing the metabolic activity in the anatomically selected volume of interest. On the other hand, a volume of interest can be selected using the metabolic information and then analyzed for correlated anatomical information using the registered MR-PET images.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"7 3-4","pages":"210-9"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12516060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of magnetic resonance imaging to physiologic and morphologic characterization of renal artery stenosis before and after angioplasty.","authors":"J Mukai, G Kershaw, P S Hees","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study describes the application of dynamic gadolinium-enhanced magnetic resonance (MR) imaging and MR angiography in the diagnosis and evaluation of the physiology of renal artery stenosis (RAS) before and after angioplasty. The MR imaging findings are discussed and compared to those of renal arteriography. MR time intensity curves of the renal cortex and medulla are obtained. Dynamic gadolinium-enhanced and angiographic MR data were abnormal in the setting of RAS and improved after angioplasty. The diagnosis of RAS could be made by visual inspection of MR dynamic images or MR angiographic images alone. Dynamic MR provides cross-sectional physiologic imaging data that compliments MR angiographic data. The role of dynamic gadolinium-enhanced MR in the evaluation of renovascular hypertension requires further investigation.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"7 3-4","pages":"220-9"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12516062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Positron emission tomography instrumentation: a review and update.","authors":"N A Mullani, N D Volkow","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Positron Emission Tomography (PET) has evolved into a powerful modality for in vivo functional imaging of the brain and the heart. Developments in PET technology and instrumentation have occurred rapidly during the last 20 years and have been driven by the requirements for improved resolution and image quality necessary for clinical and research applications. Clinical applications of PET have now been validated for the heart and the brain, and new research in the mapping of receptor density in the brain is being explored. PET cameras have developed into sophisticated imaging devices capable of both clinical and research applications. This review article updates the previous overview on PET instrumentation written by the authors with an added emphasis on performance evaluation of PET cameras. A short summary of current PET cameras available commercially is included for the purpose of comparing some important specifications between different systems.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"7 3-4","pages":"121-35"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12516882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biochemical imaging in the management of cancer.","authors":"E E Kim, T P Haynie, B T Kim","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"7 3-4","pages":"199-202"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12516059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G J Wang, N D Volkow, R Hitzemann, Z H Oster, C Roque, V Cestaro
{"title":"Brain imaging of an alcoholic with MRI, SPECT, and PET.","authors":"G J Wang, N D Volkow, R Hitzemann, Z H Oster, C Roque, V Cestaro","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A medically healthy chronic alcoholic without evidence of neurological and neuropsychological impairment was studied with magnetic resonance imaging (MRI), single photon emission computerized tomography (SPECT), and positron emission tomography (PET). An age-matched normal volunteer was evaluated with the same scans for comparison. The MRI of the alcoholic revealed prominent ventricles and mild cortical atrophy. SPECT and PET revealed predominant involvement of the frontal cortex as shown by decreased frontal blood flow and metabolism. This case illustrates the sensitivity of brain imaging techniques in detecting cerebral abnormalities even in the absence of neurologic and/or neuropsychological impairments.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"7 3-4","pages":"194-8"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12516058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utilization statistics and diagnostic accuracy of a nonhospital-based positron emission tomography center for the detection of coronary artery disease using rubidium-82.","authors":"G L Simone, N A Mullani, D A Page, B A Anderson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A retrospective analysis has been carried out to determine utilization and diagnostic accuracy of positron emission tomography of the heart with rubidium-82 at a nonhospital-based center. Utilization statistics were derived for the first 27 months of operation of the center from a total of 1,670 patients scanned. Diagnostic accuracy for detection of coronary artery disease was assessed using three readers, blinded to the clinical information, who read 225 rest and dipyridamole-stress scans of patients that had a coronary angiogram. Utilization statistics show that the center averaged 64 patients per month, 66% were males, 38% of the patients scanned had a coronary angiogram, 25% had a history of myocardial infarction, 12% had coronary artery bypass graft surgery, and 18% had percutaneous transluminal coronary angioplasty. Sensitivity was 82%, 96%, and 100% for myocardial regions perfused with greater than 67%, 84%, and 100% diameter stenosis, respectively. Specificity was 91% for all normal regions of the heart. Accuracy was 89%, 93%, and 93% for regions with greater than 67%, 84%, and 100% diameter stenosis, respectively. These results compare well with published results from major hospital based centers.</p>","PeriodicalId":76992,"journal":{"name":"American journal of physiologic imaging","volume":"7 3-4","pages":"203-9"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12516061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}