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Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry最新文献

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[A clinicopathological study of neuronal ceroid lipofuscinosis]. 神经性蜡样脂褐变的临床病理研究。
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry Pub Date : 1992-10-01
B Xiao
{"title":"[A clinicopathological study of neuronal ceroid lipofuscinosis].","authors":"B Xiao","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>4 unrelated patients with infantile type (one case), late infantile type (one case), juvenile type (two case) of neuronal ceroid-lipofuscinosis were reported. The pathological study by brain biopsy was carried out with light and electron microscopes as well as histochemical methods. Ultrastructurally, the infantile type showed deposits of lipofuscin bodies, fingerprint bodies, and the late infantile type showed a lot of curvilinear bodies and paracrystalline bodies. The ultrastructural configuration in the juvenile type is more heterogeneous and consisted of combination of lipofuscin bodies, fingerprint bodies and multilamellar structures. It was emphasized that fingerprint bodies were first discovered in infantile type, which might challenge the view that only lipofuscin bodies can be found in infantile type.</p>","PeriodicalId":76874,"journal":{"name":"Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry","volume":"25 5","pages":"278-80, 316"},"PeriodicalIF":0.0,"publicationDate":"1992-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12466497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Predicting the effects of haloperidol on schizophrenics by quantitative pharmaco-EEG]. [定量药物-脑电图预测氟哌啶醇对精神分裂症患者的影响]。
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry Pub Date : 1992-10-01
X L Zhang
{"title":"[Predicting the effects of haloperidol on schizophrenics by quantitative pharmaco-EEG].","authors":"X L Zhang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In order to predict the short-term-outcome of schizophrenics under the treatment of haloperidol, changes of 15 schizophrenic subjects' EEG after 4 mg haloperidol oral intake were monitored with the method of QPEEG. The result of discriminate analysis showed that the more similar to typical EEG pattern of neuroleptics the patients showed, the better the patients responded to haloperidol treatment. Meanwhile, the haloperidol therapeutic mechanisms of brain electro-physiology and the electro-physiological characteristics of schizophrenics were also discussed.</p>","PeriodicalId":76874,"journal":{"name":"Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry","volume":"25 5","pages":"300-2, 318"},"PeriodicalIF":0.0,"publicationDate":"1992-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12466502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A study on middle cerebral artery territory infarction with transcranial Doppler sonography]. 经颅多普勒超声对大脑中动脉区域梗死的研究。
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry Pub Date : 1992-10-01
X S Ni
{"title":"[A study on middle cerebral artery territory infarction with transcranial Doppler sonography].","authors":"X S Ni","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The transcranial Doppler sonographic findings of 40 patients with middle cerebral artery (MCA) territory infarction were compared with those of 40 controls. The results showed that in the group of acute phase patients there was a large reduction of MCA mean flow velocity (Vm) of the infarcted side compared with the normal hemisphere (P < 0.01) and controls (P < 0.05). At the same time the anterior cerebral artery (ACA) Vm rose on both sides (esp. on the infarcted side) in comparison with controls (P < 0.05). The posterior cerebral artery (PCA) Vm did not change significantly (P > 0.05). In the group of chronic phase patients there were changes similar to the group of acute phase patients in MCA Vm and ACA Vm, but not statistically significant. Follow-up TCD examinations were carried out in 8 cases during the acute phase of stroke. We found that the decreased MCA Vm on the infarcted side returned to normal in 4 cases, remained lower in another 2 cases within 4 weeks after onset. The increased MCA Vm on the infarcted side in 2 cases returned to normal within 2 weeks after onset. Various types of TCD findings in patients with MCA occlusion were described and analysed.</p>","PeriodicalId":76874,"journal":{"name":"Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry","volume":"25 5","pages":"264-6, 315"},"PeriodicalIF":0.0,"publicationDate":"1992-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12466494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[ELISA for detection of anti-filamin antibody in sera from patient with myasthenia gravis]. [ELISA法检测重症肌无力患者血清中抗丝蛋白抗体]。
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry Pub Date : 1992-10-01
H Lin
{"title":"[ELISA for detection of anti-filamin antibody in sera from patient with myasthenia gravis].","authors":"H Lin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The activity of anti-filamin antibody was determined in sera from 128 patients with myasthenia gravis (MG) by enzyme-linked immunosorbent assay (ELISA). The positive rate was 77.34%. No correlation was observed between anti-F-ab and nAchRab and CAEab. The antibody-absorbtion test were positive. The result demonstrated that anti-F-ab may play some role in the pathology of MG. The clinical use of ELISA for detection of anti-F-ab may help to diagnose MG.</p>","PeriodicalId":76874,"journal":{"name":"Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry","volume":"25 5","pages":"281-3, 316-7"},"PeriodicalIF":0.0,"publicationDate":"1992-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12466498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The diagnostic value of magnetic resonance imaging on neuromuscular diseases]. 【磁共振成像对神经肌肉疾病的诊断价值】
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry Pub Date : 1992-10-01
Q T Chen
{"title":"[The diagnostic value of magnetic resonance imaging on neuromuscular diseases].","authors":"Q T Chen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The article concentrated on the study of skeletal muscles of four extremities in 12 cases of different kinds of neuromuscular diseases and 4 volunteers with MRI. The results revealed: MRI could clearly display individual muscle, muscle groups or abnormal muscles morphologically. It could also demonstrate the difference between the neurogenic and myogenic changes. In patients with progressive muscular dystrophy (PMD), the gracilis m. and sartorius m. were relatively intact. In patients with primary myopathies, the severity of MRI changes was consistent with the severity of the illness and the EMG changes. The results indicated that MRI examination was helpful in the diagnosis of neuromuscular disorders. It can define the distribution and the severity of impaired muscles. In addition, MRI could be used to select the appropriate muscles for EMG examinations or muscle biopsies. Selective muscular impairments might be the characteristics of patients with PMD.</p>","PeriodicalId":76874,"journal":{"name":"Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry","volume":"25 5","pages":"267-70, 315-6"},"PeriodicalIF":0.0,"publicationDate":"1992-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12466495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The effect of antipsychotic drugs on dopamine-receptors on caudate calf]. 抗精神病药物对尾状小腿多巴胺受体的影响。
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry Pub Date : 1992-10-01
Q Y Guo
{"title":"[The effect of antipsychotic drugs on dopamine-receptors on caudate calf].","authors":"Q Y Guo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Using radioligand receptor binding assay (RRA), dopamine receptor in the calf caudate were identified with 3H-Spiperone as radioactive ligand. The total number of maximal binding sites (Bmax), the equilibrium dissociation affinity (Kd), the concentrations of drug required to inhibited 50% specific binding (Ic50) and competitive inhibition constant (Ki) of antipsychotics in calf caudate were determined by sturative binding experiment and inhibitive binding experiment. The result showed the mean Bmax was 0.659 pmol/mg protein membrane and Kd was 0.31 nmol/L. Scatchard analysis denotes that it was hyperbole and there were two binding positions in calf caudte. Antipsychotics can inhibit 3H-Spiperone binding specifically the order of affinity constants (1/Ki) was Haloperdol and sulpiride, Chlorpromazine and Clozapin, Tranquis and Taractan. This abilities of drugs to compete with 3H-Spi binding will be used as basis of RRA for measuring blood levels of antipsychotics.</p>","PeriodicalId":76874,"journal":{"name":"Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry","volume":"25 5","pages":"296-9, 317-8"},"PeriodicalIF":0.0,"publicationDate":"1992-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12535921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A study on effects of parents age, birth order and mental retardation of unknown etiology]. [父母年龄、出生顺序与不明原因智力低下影响的研究]。
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry Pub Date : 1992-10-01
S L Zhang
{"title":"[A study on effects of parents age, birth order and mental retardation of unknown etiology].","authors":"S L Zhang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>On this report 461 matched cases of mental retardation of unknown aetiology were analysed on the relationship between the diseases and the parents age, birth orders with conditional Logistic regression. These cases were accurately diagnosed and selected from the Epidemiologic Survey of genetic diseases of Sichuan, China. The results found that mental retardation of unknown aetiology is related to the age of parents and birth order. The paternal age is the main factor while the maternal age in not a significant effect and birth order also in not a significant effect after readjusting the other factors. Compared to paternal age group of under 25. There are significant increase of relative risks of age group 30-34 and 45 above, about 1.8 and 2.7 fold increase in univariate analysis and 1.9 and 3.3 fold increase in controlling the maternal age and birth order, a chi-square test for trend of distribution of paternal age also indicates a significant dose response relationship between increasing risk with age. The significance of result and methods of analysis were discussed.</p>","PeriodicalId":76874,"journal":{"name":"Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry","volume":"25 5","pages":"303-5, 318"},"PeriodicalIF":0.0,"publicationDate":"1992-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12465665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Later onset metachromatic leukodystrophy diagnosed by nerve biopsy]. [神经活检诊断后发性异色性脑白质营养不良]。
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry Pub Date : 1992-10-01
J X Zhao
{"title":"[Later onset metachromatic leukodystrophy diagnosed by nerve biopsy].","authors":"J X Zhao","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Three cases of later onset metachromatic leukodystrophy in one family were reported. The brother is 32 years old, younger sister is 35 years old and the elder sister is 39 years old, who were normal as child without any family history of neurological disease. The three cases began their illness at about the age of 30 years old with dysarthria, progressive dementia, motor disturbance and numbness in the extremities. CT scan showed low density in the white matter of frontal, parietal lobes and around the ventricle. The written reports of CT scan were lacunar infarction in brother, multiple lacunar infarction in younger sister and Binswanger's disease in elder sister. Nerve biopsy showed myelinated fibers were decreased in number. Metachromatical materials were seen in and around the Schwann cell cytoplasm. Metachromatical materials were lamillar inclusions in granular matrix by electromicroscopic examination. So nerve biopsy is easy, safe and effective method to diagnose the uncertain pathogenic leukoence-phalopathy.</p>","PeriodicalId":76874,"journal":{"name":"Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry","volume":"25 5","pages":"271-2, 316"},"PeriodicalIF":0.0,"publicationDate":"1992-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12511599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hereditary motor and sensory neuropathy]. 遗传性运动和感觉神经病变。
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry Pub Date : 1992-10-01
Y P Guo
{"title":"[Hereditary motor and sensory neuropathy].","authors":"Y P Guo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The report consisted of 10 cases of hereditary motor and sensory neuropathy (HMSN). There were 7 males and 3 females. Their ages ranged from 11 to 42 (average 24.6) years, ages of onset varied from 7 to 34 (average 17.3) years. Hereditary history was showed in 4 cases. The clinical features of all 10 cases had peroneal muscular atrophy, 8 of 10 cases also had involvement of the upper limbs, 7 of 10 cases had pes arcuatus. The conduction velocity was obviously slow in 5 cases and slightly slow in the others. Oion-bulb hypertrophic neuropathy was demonstrated in sural nerve biopsies of 5 cases. Neuronal axonal degeneration were found in the remaining 5 cases. Clinical classification, clinical features and pathological characteristics were discussed.</p>","PeriodicalId":76874,"journal":{"name":"Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry","volume":"25 5","pages":"261-3, 315"},"PeriodicalIF":0.0,"publicationDate":"1992-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12465804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Distribution of common symptoms in 2500 schizophrenics and their comparative analysis on the background of times and culture]. [2500名精神分裂症患者常见症状分布及其时代文化背景的比较分析]。
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry Pub Date : 1992-10-01
M K Lu
{"title":"[Distribution of common symptoms in 2500 schizophrenics and their comparative analysis on the background of times and culture].","authors":"M K Lu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the paper, the distribution of the common symptoms in 2,500 Schizophrenics was reported, including 1,600 cases in Shanghai Mental Health Center, 500 cases in Chuan Sha County Mental Hospital, 200 cases in Nan Hui County Mental Hospital in Shanghai and 200 cases in Su County Mental Hospital in An Hui province respectively. In the 2,500 cases, apart from 1,600 cases including 500 cases discharged from 1964 to 1965, and 500 cases discharged from 1984 to 1985 in Shanghai Mental Health Center, the rest was hospitalizing during 1988 to august of 1990. Among these patients, 67 symptoms were shown in which 47 symptoms were much common. There was the most significant difference in the 22 symptoms of the 23 much more common symptoms between 1960 and 1980s (P < 0.01). According to the comparison of the various cultural background, there was the most significant difference in 15 symptoms (P < 0.01).</p>","PeriodicalId":76874,"journal":{"name":"Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry","volume":"25 5","pages":"291-5, 317"},"PeriodicalIF":0.0,"publicationDate":"1992-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12466501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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