[Predicting the effects of haloperidol on schizophrenics by quantitative pharmaco-EEG].

Abstract

In order to predict the short-term-outcome of schizophrenics under the treatment of haloperidol, changes of 15 schizophrenic subjects' EEG after 4 mg haloperidol oral intake were monitored with the method of QPEEG. The result of discriminate analysis showed that the more similar to typical EEG pattern of neuroleptics the patients showed, the better the patients responded to haloperidol treatment. Meanwhile, the haloperidol therapeutic mechanisms of brain electro-physiology and the electro-physiological characteristics of schizophrenics were also discussed.