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The physiology of the testes in the Göttingen mini pig. Göttingen迷你猪的睾丸生理学。
Zeitschrift fur Versuchstierkunde Pub Date : 1989-01-01
C J Myren, N Einer-Jensen, P Bennett
{"title":"The physiology of the testes in the Göttingen mini pig.","authors":"C J Myren,&nbsp;N Einer-Jensen,&nbsp;P Bennett","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Capillary blood flow (133xenon clearance), deep testicular and muscle temperature (needle thermistor) and androgenic hormone concentrations in peripheral blood samples (RIA) were measured and the histology (needle biopsies) evaluated in 16 anaesthetized, mature Göttingen mini pigs. The blood flow was 0.26 +/- 0.10 ml x g-1 x min-1. The testicular temperature was 33.6 +/- 1.4 degrees C, and the body temperature 37.2 +/- 0.9 degrees C. The plasma levels of testosterone were 15.2 +/- 10.1 nmol x l-1, of dihydrotestosterone 0.99 +/- 0.98 nmol x l-1, dehydro-epi-androsterone sulphate 441 +/- 333, nmol x l-1, and the delta-4 androstenedione level was 9.2 +/- 7.0 nmol x l-1. Sexual-hormone-binding-globulin was immeasurable. The histological appearance was judged to 7.8 +/- 1.0 by a testicular biopsy score (scale 10-1). The results from the present investigation are in the same range of order as in other mammals and it is concluded that the mature, male Göttingen mini pig is a useful model for reproductive research.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"32 4","pages":"183-7"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13769959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Realization of an online connection of laboratory apparatus with personal computers]. 实验室设备与个人计算机在线连接的实现。
Zeitschrift fur Versuchstierkunde Pub Date : 1989-01-01
M Schliack, B Rattel
{"title":"[Realization of an online connection of laboratory apparatus with personal computers].","authors":"M Schliack,&nbsp;B Rattel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Online data transfer from laboratory equipment to personal computer is more and more accepted as standard for animal experiments. This paper deals with the connection of the laboratory devices to the computer by using the serial RS-232C interface. Both the simplex and the duplex mode of data transfer are described as well as a fundamental concept of data handling in BASIC.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"32 6","pages":"241-7"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13834797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of a new, simple method for quantitative collection of 24-hour urines in small laboratory animals: determination of basal excretion of proteins, creatinine, urea, electrolytes, and of free steroids. 小型实验动物24小时尿液定量采集新方法的应用:测定蛋白质、肌酐、尿素、电解质和游离类固醇的基础排泄。
Zeitschrift fur Versuchstierkunde Pub Date : 1989-01-01
M Fenske
{"title":"Application of a new, simple method for quantitative collection of 24-hour urines in small laboratory animals: determination of basal excretion of proteins, creatinine, urea, electrolytes, and of free steroids.","authors":"M Fenske","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The application of a simple method for collection of 24-hour urines in laboratory animals is described and basal excretion values of urinary proteins, creatinine, urea, electrolytes and of free steroids (glucocorticosteroids, DHEA, progesterone, testosterone) in small laboratory animals like the Mongolian gerbil, rat, guinea pig and tree shrew were measured. The major advantage of this method is that cages are identical in size to animal's home cages, are easily constructed and cheap, and that dried and liquid portions of each 24-hour urine are quantitatively removed from aluminium sheets by a simple washing step. This facilitates the monitoring of changes of urinary excretion rates over longer time periods without stressing the animals by handling.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"32 2","pages":"65-70"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13896351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Microbiological development studies in a clinically healthy, closed primate colony (Macaca mulatta, Macaca arctoides) after the establishment of a Salmonella infection]. [在临床健康、封闭的灵长类动物群体(猕猴、猕猴)感染沙门氏菌后的微生物发育研究]。
Zeitschrift fur Versuchstierkunde Pub Date : 1989-01-01
H P Hamann, M Zschöck, W Herbst, K Fischbach, K Seeger, R Weiss, T Schliesser
{"title":"[Microbiological development studies in a clinically healthy, closed primate colony (Macaca mulatta, Macaca arctoides) after the establishment of a Salmonella infection].","authors":"H P Hamann,&nbsp;M Zschöck,&nbsp;W Herbst,&nbsp;K Fischbach,&nbsp;K Seeger,&nbsp;R Weiss,&nbsp;T Schliesser","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A case of a Salmonella infantis septicemia in a primate (Macaca mulatta) probably induced by shipment stress gave rise to microbiological examination of fecal samples from all animals of a since 1976 closed colony of Macaca mulatta and Macaca arctoides. During 3 investigations carried out in 3 week intervals salmonella-positive animals were separated immediately from the stock. At the first examination 3 of 52, and at the second 2 of 49 samples were found to be salmonella-positive. At the third series all of the remaining 47 animals proved to be salmonella-negative. All isolates were identified as S. infantis. Feeding of contaminated, dried prawns was suspected as the most probable source of infection. A simultaneous examination of 96 of the stool specimens revealed Y. enterocolitica in 4 samples. Additionally, electron-microscopy of pooled fecal samples (3 to 4 animals each) led to demonstration of corona-, adenovirus and small round virus-like particles in one pool each. Moreover, coronavirus-like particles could be detected in 7 of 13 (1st examination series), 5 of 15 (2nd series) and 1 of 13 pools (3rd series).</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"32 3","pages":"105-9"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13920096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification and clinical examination of jaundiced rats. 黄疸大鼠的鉴定及临床检查。
Zeitschrift fur Versuchstierkunde Pub Date : 1989-01-01
A C Beynen, V Baumans, A P Bertens, J W Haas, H van Herck, F R Stafleu, G van Tintelen
{"title":"Identification and clinical examination of jaundiced rats.","authors":"A C Beynen,&nbsp;V Baumans,&nbsp;A P Bertens,&nbsp;J W Haas,&nbsp;H van Herck,&nbsp;F R Stafleu,&nbsp;G van Tintelen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Rats with or without spontaneously occurring jaundice were clinically examined. Jaundiced rats had five-fold higher serum bilirubin concentrations than control animals. About 90% of serum bilirubin in the jaundiced animals was in conjugated form. Control and jaundiced rats did not differ with respect to clinical signs such as alertness, stance, hair coat, position of eyes, discharge from eyes and nose, and cleanliness of anal orifice. While examined individually, jaundiced rats could not be identified readily on the basis of a yellow colour of sole of feet, nose, ears and tail. When kept together with control rats, jaundiced rats could be selected reasonably well. Urines of jaundiced rats had a more intense yellow colour than urines of control animals. Rats with jaundice were significantly more active in a small open field test than control rats.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"32 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13853109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of the DENTACRYL rapid (Spofa) resin for preparation of the rat tracheobronchial casts. 采用DENTACRYL快速(Spofa)树脂制备大鼠气管支气管铸型。
Zeitschrift fur Versuchstierkunde Pub Date : 1989-01-01
J Havránková, V Skoda, R Holusa
{"title":"The use of the DENTACRYL rapid (Spofa) resin for preparation of the rat tracheobronchial casts.","authors":"J Havránková,&nbsp;V Skoda,&nbsp;R Holusa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We have made tracheobronchial casts of the rat lungs using DENTACRYL Rapid (Spofa)--the synthetic methacrylic resin of Czechoslovak origin. The details of the method are fully described. The differences between preparations of the intact rat tracheobronchial trees and those of the rats after quartz instillation are illustrated. These differences are analogous to the commonly described changes in bronchograms.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"32 2","pages":"97-100"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13897041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[26th scientific meeting of the Society of Laboratory Animal Science. Basel, September 13-15, 1988. Abstracts]. 第26届实验动物科学学会科学会议。巴塞尔，1988年9月13日至15日。摘要]。
Zeitschrift fur Versuchstierkunde Pub Date : 1989-01-01
{"title":"[26th scientific meeting of the Society of Laboratory Animal Science. Basel, September 13-15, 1988. Abstracts].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"32 5","pages":"193-233"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13760545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Use of direct calorimetry for continuously following the course of experimental infections in the mouse]. [使用直接量热法连续跟踪小鼠的实验感染过程]。
Zeitschrift fur Versuchstierkunde Pub Date : 1989-01-01
R Stracke, A Veckenstedt, H Knappe, E Bauer
{"title":"[Use of direct calorimetry for continuously following the course of experimental infections in the mouse].","authors":"R Stracke,&nbsp;A Veckenstedt,&nbsp;H Knappe,&nbsp;E Bauer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To obtain information about early symptoms of infection measurements of heat production were performed in experimentally infected animals. As a model Mengo virus-infected mice were used. Construction and physical properties of the flow calorimeter device are described. Fever was not detected by method used. However, deviations from normal behaviour of the animals were demonstrated as a result of the relationship between motoric activity and heat produced. Furthermore, the method may be particularly useful for the determination of the exact time of death, which is of interest for mathematical modelling of survival data (RECKNAGEL et al. 1986; GUTHKE et al. 1987; SUHNEL und VECKENSTEDT 1989).</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"32 3","pages":"141-9"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13695091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Therapy proposals for the quarantine of African green monkeys (Cercopithecus aethiops)]. 非洲绿猴(Cercopithecus aethiops)检疫的处理建议。
Zeitschrift fur Versuchstierkunde Pub Date : 1989-01-01
C Abel, R Eppler, P Hlinak, G Weigand
{"title":"[Therapy proposals for the quarantine of African green monkeys (Cercopithecus aethiops)].","authors":"C Abel,&nbsp;R Eppler,&nbsp;P Hlinak,&nbsp;G Weigand","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Attenuated live virus vaccines are usually tested in vivo for neurovirulent properties by using African green monkeys. This report describes the health condition of animals that have been imported from Ethiopia. The monkeys were strongly malnourished when they arrived at the institute. One animal died during the shipment. In spite of many diagnostic and therapeutic efforts only 14 of 29 monkeys survived the 120-day-quarantine. Most animals died of infections of the respiratory and gastrointestinal tracts within 4 weeks after arrival.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"32 4","pages":"167-70"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13769956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increase of the intestinal iron absorption in growing rats and mice after 8 days of iron-deficient feeding. 缺铁喂养8 d后生长大鼠和小鼠肠道铁吸收的增加。
Zeitschrift fur Versuchstierkunde Pub Date : 1989-01-01
K Schümann, B Elsenhans, G Hunder, G Strugala, W Forth
{"title":"Increase of the intestinal iron absorption in growing rats and mice after 8 days of iron-deficient feeding.","authors":"K Schümann,&nbsp;B Elsenhans,&nbsp;G Hunder,&nbsp;G Strugala,&nbsp;W Forth","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In investigations of intestinal iron absorption the combination of repetitive bleeding and iron-deficient feeding is frequently used. It induces iron deficiency which, in turn, stimulates iron absorption. When this combined procedure was compared with the effect of an 8 d iron-deficient feeding schedule in growing rats, no significant differences were found regarding the stimulating effect on intestinal iron transfer. Body iron stores, however, as represented by the hepatic ferritin and iron content are remarkably less depleted. Contrary to the effect of the combined procedure the animals growth was only marginally retarded and anaemia did not develop. This was also demonstrated in mice. The stimulation of intestinal iron absorption by iron-deficient feeding of growing animals thus seems preferable, as this procedure largely avoids the disturbing side effects observed with repetitive blood sampling.</p>","PeriodicalId":76864,"journal":{"name":"Zeitschrift fur Versuchstierkunde","volume":"32 6","pages":"261-7"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13760550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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