AIDS reviews最新文献

{"title":"Current challenges in caring for injection drug users with human immunodeficiency virus infection in Pakistan.","authors":"Khair Muhammad, Faiqa Yaseen, Humera Akhtar","doi":"10.24875/AIDSRev.26000002","DOIUrl":"10.24875/AIDSRev.26000002","url":null,"abstract":"<p><p>The stigmatized status of injecting illicit drugs use and human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome in Pakistan, enlists HIV positive injection drug users (IDUs) at preeminent risk for poor mental health. This study aims to investigate the potential link between enacted HIV stigma, community attachment, and mental health problems in HIV-positive IDUs, along with mediating role of community attachment and moderating role of drug type. Correlation analysis revealed that enacted HIV stigma and community attachment were significantly negatively associated with mental health. Mediation analysis indicated that enacted HIV stigma influences mental health indirectly by shaping individuals' level of attachment to the community of IDUs. Moderation analysis revealed that synthetic illicit drugs significantly moderated the association between enacted HIV stigma and mental health. The findings highlight the need for targeted interventions addressing enacted HIV stigma among IDUs to effectively improve their mental health outcomes.</p>","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":" ","pages":"95-103"},"PeriodicalIF":2.0,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148534855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic review and meta-analysis of risk prediction models for HIV testing in key populations.","authors":"Xin Xie, Chaowen Zhang, Shuyu Han, Yirong Shi, Jinyang Ming, Weimei Chen, Jingxian Hu, Bo Zhou, Lili Zhang","doi":"10.24875/AIDSRev.26000004","DOIUrl":"https://doi.org/10.24875/AIDSRev.26000004","url":null,"abstract":"<p><p>HIV testing is a critical tool for preventing HIV transmission, with early identification in key populations reducing onward spread. This study aims to evaluate risk prediction models, identify factors influencing HIV testing, and provide recommendations to enhance testing among key populations. Electronic databases were searched for peer-reviewed and gray literature published in English and Chinese from January 1, 1996, to November 14, 2025. Two reviewers independently assessed methodological quality and extracted data. The prediction model risk of bias assessment tool was used to evaluate bias and applicability. Of 3693 initially identified studies, seven met the inclusion criteria. Reported area under the curve (AUC) values ranged from 0.72 to 0.82, and the pooled AUC of validated models was 0.77 (95% confidence interval: 0.70-0.84), indicating moderate discriminative performance. However, most of the studies were assessed as having a high risk of bias, primarily due to insufficient reporting in the analysis domain, limiting the reliability of existing models for clinical or public health applications. Predictors of HIV testing were broadly grouped into sociodemographic, behavioral, knowledge-related, and structural factors, and predictors of HIV testing varied considerably across models, reflecting differences in study populations, behavioral characteristics, and contextual factors across settings. Overall, although existing models demonstrate moderate predictive ability, their methodological limitations and lack of external validation restrict their generalizability and practical utility. Therefore, reliable prediction models remain limited. Future research should develop high-quality models with larger sample sizes, robust designs, and multi-center external validation to support clinical application, improve practical relevance, and inform strategies to advance HIV testing. Beyond HIV testing prediction, this study highlights the need for broader prevention approaches, including sexuality education, risk awareness, and safe sexual behaviors, alongside targeted testing interventions.</p>","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148215932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hantavirus outbreak in a cruise departing from Argentina.","authors":"Vicente Soriano","doi":"10.24875/AIDSRev.M26000096","DOIUrl":"10.24875/AIDSRev.M26000096","url":null,"abstract":"","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":" ","pages":"80-80"},"PeriodicalIF":2.0,"publicationDate":"2026-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148004379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dolutegravir shows efficacy in HTLV-1 infection.","authors":"Vicente Soriano","doi":"10.24875/AIDSRev.M26000095","DOIUrl":"10.24875/AIDSRev.M26000095","url":null,"abstract":"","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":" ","pages":"83-84"},"PeriodicalIF":2.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antiretroviral therapy \"à la carte\".","authors":"Vicente Soriano","doi":"10.24875/AIDSRev.M26000094","DOIUrl":"10.24875/AIDSRev.M26000094","url":null,"abstract":"","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":" ","pages":"81-82"},"PeriodicalIF":2.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147626865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global research landscape of two-drug regimens for HIV treatment: a visual bibliometric analysis.","authors":"Can Huang, Yanfang Sun, Meng Chen, Lin Zhang, Wei Liu","doi":"10.24875/AIDSRev.25000029","DOIUrl":"10.24875/AIDSRev.25000029","url":null,"abstract":"<p><p>With the advancement of antiretroviral therapy, two-drug regimens have emerged as a viable and promising strategy for human immunodeficiency virus (HIV) care and management, offering potential advantages in safety, treatment adherence, and cost-effectiveness. Although scholarly interest in this field is growing, a comprehensive bibliometric analysis remains lacking; accordingly, this study aimed to map the research landscape, identify emerging trends, and explore collaborative networks in the field of two-drug HIV treatment regimens. To this end, studies on two-drug HIV treatment regimens were retrieved from the Web of Science Core Collection. After screening and deduplication, key bibliometric data were extracted. Subsequent analyses were performed using the Bibliometrix R-package and VOSviewer to visualize annual publication output, geographical distribution, institutional collaborations, journal influence, author networks, and keyword evolution trends. Ultimately, 3,262 publications were included, with an annual growth rate of 9.23%. The United States was the most productive country (974 publications, 29.9%), while Harvard University topped institutional rankings (430 publications). AIDS was the leading journal (199 publications), and core authors (e.g., Carr A) contributed substantially. Keyword analysis revealed that two-drug regimens are transitioning from \"alternative options\" to \"mainstream choices\" in HIV treatment, with their development reflecting a focus on balancing efficacy and safety, as well as aligning technological innovation with clinical demands. This bibliometric study delineates the evolving landscape of two-drug HIV treatment research, with North America and Europe making prominent contributions. It highlights key research foci and collaboration patterns, providing valuable insights for researchers, clinicians, and policymakers to prioritize future research and optimize HIV treatment strategies.</p>","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"28 1","pages":"30-39"},"PeriodicalIF":2.0,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147626885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Google <i>DeepMind</i> unlock the mystery of life's origin?","authors":"Vicente Soriano","doi":"10.24875/AIDSRev.M26000093","DOIUrl":"https://doi.org/10.24875/AIDSRev.M26000093","url":null,"abstract":"","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146225300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extending longevity beyond the biological clock and the Dorian Gray syndrome.","authors":"Vicente Soriano","doi":"10.24875/AIDSRev.M26000092","DOIUrl":"https://doi.org/10.24875/AIDSRev.M26000092","url":null,"abstract":"","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146148888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving treatment adherence among people living with HIV through adherence counseling: a scoping review.","authors":"Iismayanti Nursalam, Krisnana Ilya, Pandin G R Moses, Insani-Latif Aulia","doi":"10.24875/AIDSRev.26000001","DOIUrl":"https://doi.org/10.24875/AIDSRev.26000001","url":null,"abstract":"<p><p>HIV remains a major global public health challenge. Although antiretroviral therapy (ART) effectively reduces morbidity and mortality, its success depends on sustained adherence to treatment. Barriers such as stigma, psychosocial problems, and limited access to healthcare continue to compromise adherence among people living with HIV (PLHIV). Adherence counseling (AC) has been increasingly implemented to address these challenges and improve treatment outcomes. This study aimed to map and synthesize the types and effectiveness of AC interventions in improving ART adherence among PLHIV. A scoping review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews guidelines. Literature searches were performed in Scopus, ScienceDirect, ProQuest, and PubMed using population, intervention, comparison, and outcomes-based keywords. Eligible studies evaluated AC interventions with ART adherence as an outcome and were published in the last 5 years. Of the 689 identified articles, 13 met the inclusion criteria. Most studies were conducted in Uganda and focused on intensive AC (IAC). IAC improves ART adherence and viral load suppression, particularly when delivered through structured, patient-centered approaches. However, the effectiveness varied according to social, health system, and contextual factors. Digital-based interventions, including real-time medication monitoring and mobile health applications, have also demonstrated promising effects on adherence. IAC plays an important role in improving ART adherence among PLHIV. Its effectiveness is influenced by the quality of counseling, social support, and health system integration. Combining face-to-face counseling with digital innovations and community-based support offers the most sustainable strategy for enhancing adherence and achieving viral suppression in PLHIV.</p>","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"28 2","pages":"71-79"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148468445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital health innovation in HIV prevention and sexual health promotion: current applications and future prospects of mobile health and telehealth.","authors":"Xiaohe Sun","doi":"10.24875/AIDSRev.26000006","DOIUrl":"https://doi.org/10.24875/AIDSRev.26000006","url":null,"abstract":"<p><p>Digital health is now a delivery strategy for HIV prevention and sexual health promotion, not simply a channel for health education. Mobile messaging, web-based testing, HIV self-testing (HIVST) support, mobile applications, social media recruitment, telehealth, tele-pre-exposure prophylaxis (PrEP), and chatbot-assisted workflows can reduce barriers related to stigma, distance, clinic capacity, and confidentiality. These tools also create an opportunity for primary HIV and sexually transmitted infection (STI) prevention before high-risk patterns are established, using positive, age-appropriate messages that support consent, healthy relationships, condom and vaccine uptake, timely testing, and informed prevention choices. This narrative review synthesizes evidence from trials, systematic reviews, implementation studies, and program evaluations, emphasizing quantitative outcomes and implementation limits. The most consistent benefits are seen for service actions with clear endpoints: HIVST, online STI testing, PrEP initiation through telehealth, and interactive text-message support for adherence. Effects are less consistent for sustained PrEP persistence, complex behavior change, linkage after reactive self-tests, and equity. Digital tools can improve access among men who have sex with men, adolescents and young adults, women, sex workers, and rural populations. Still, they can also reproduce inequities when privacy, cost, literacy, device access, legal vulnerability, and laboratory infrastructure are not addressed. Future systems should integrate prevention education and digital entry points with laboratories, pharmacies, clinicians, community navigators, human escalation, privacy governance, and equity monitoring. The field should now move from platform-centered pilots toward accountable hybrid sexual health systems.</p>","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"28 3","pages":"104-117"},"PeriodicalIF":2.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149163640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}