AIDS reviews最新文献_第2页

Baseline characteristics of people living with HIV with different CD4(+) T cell depletion. 不同CD4(+) T细胞耗竭的HIV感染者的基线特征

IF 2.5 4区医学

AIDS reviews Pub Date : 2025-12-11 DOI: 10.24875/AIDSRev.25000027

Peipei Luo, Juan Jin, Dingsheng Kong, Guoxiang Yang

引用次数: 0

Global incidence of chlamydia infection and HIV pre-exposure prophylaxis. 衣原体感染的全球发病率和HIV暴露前预防。

IF 2.5 4区医学

AIDS reviews Pub Date : 2025-12-11 DOI: 10.24875/AIDSRev.25000026

Xiaoyu Zhou, Liping Wan, Dandi Chen, Lihua Huang

引用次数: 0

Avian influenza in the context of a pandemic challenge. 在大流行挑战背景下的禽流感。

IF 2.5 4区医学

AIDS reviews Pub Date : 2025-12-10 DOI: 10.24875/AIDSRev.M25000089

Estanislao Nistal-Villán, Iván Sanz-Muñoz, José M Eiros, Adolfo García-Sastre

引用次数: 0

HIV-1 genotyping and drug resistance mutations in Morocco (2009-2024): a systematic review addressing critical gaps in molecular surveillance. 摩洛哥HIV-1基因分型和耐药突变（2009-2024）：解决分子监测关键空白的系统综述

IF 2.5 4区医学

AIDS reviews Pub Date : 2025-12-10 DOI: 10.24875/AIDSRev.25000022

Maryam Ahmina, Nada Lamrak, Hicham El Annaz, Mohamed Rida-Tagagidid, Rachid Abi, Mohamed Elqatni, Abdelilah Laraqi, Safae Elkochri, Elarbi Bouaiti, Ahmed Reggad, Youssef Addi, Bouchra El Mchichi, Nadia Touil, Khalid Ennibi, Idriss Amine Lahlou

{"title":"HIV-1 genotyping and drug resistance mutations in Morocco (2009-2024): a systematic review addressing critical gaps in molecular surveillance.","authors":"Maryam Ahmina, Nada Lamrak, Hicham El Annaz, Mohamed Rida-Tagagidid, Rachid Abi, Mohamed Elqatni, Abdelilah Laraqi, Safae Elkochri, Elarbi Bouaiti, Ahmed Reggad, Youssef Addi, Bouchra El Mchichi, Nadia Touil, Khalid Ennibi, Idriss Amine Lahlou","doi":"10.24875/AIDSRev.25000022","DOIUrl":"10.24875/AIDSRev.25000022","url":null,"abstract":"The growing use of antiretroviral therapy (ART) has transformed HIV infection into a chronic, manageable disease, yet the emergence of drug resistance continues to threaten global progress. Morocco, located at the crossroads of Sub-Saharan Africa and Europe, offers a unique context for understanding the molecular evolution of HIV in the Middle East and North Africa. This systematic review synthesizes all available data on HIV-1 genotyping and resistance mutations in Morocco from 2009 to 2024, providing the first national overview of molecular resistance patterns. Six studies comprising 673 individuals met the inclusion criteria, spanning 2004-2015. Subtype B predominated (73.8%), followed by CRF02_AG (17.6%), reflecting increasing viral diversification linked to cross-regional transmission. Among ART-experienced patients, acquired drug resistance reached 19.5% at the population level and 53.3% among successfully sequenced samples, with NRTI (48.9%) and PI (22.2%) mutations predominating. The most frequent mutations were M184V (44%), K103N (8.9%), and V82A/L (13.3%). In ART-naïve individuals, transmitted resistance remained limited (1.55%), with no major integrase strand-transfer inhibitor mutations detected, though accessory polymorphisms such as L74M/I and E157Q were present in 3-5% of cases. CD4 counts and viral load suppression improved in later cohorts. These findings underline the critical need to re-establish molecular surveillance in Morocco to capture post-2019 resistance dynamics under dolutegravir-based therapy. Strengthening genotypic monitoring and integrating resistance testing into clinical care will be pivotal to preserving long-term ART efficacy and achieving the UNAIDS 95-95-95 and HIV elimination targets by 2030.","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":" ","pages":"1-12"},"PeriodicalIF":2.5,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145720316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research trends and hotspots in HIV pre-exposure prophylaxis: a bibliometric analysis and visual mapping. HIV暴露前预防的研究趋势和热点：文献计量分析和可视化制图。

IF 2.5 4区医学

AIDS reviews Pub Date : 2025-12-01 DOI: 10.24875/AIDSRev.25000012

Can Huang, Lin Zhang, Meng Chen, Yanfang Sun, Wei Liu

{"title":"Research trends and hotspots in HIV pre-exposure prophylaxis: a bibliometric analysis and visual mapping.","authors":"Can Huang, Lin Zhang, Meng Chen, Yanfang Sun, Wei Liu","doi":"10.24875/AIDSRev.25000012","DOIUrl":"10.24875/AIDSRev.25000012","url":null,"abstract":"HIV remains a major global public health challenge, and pre-exposure prophylaxis (PrEP) has established itself as a pivotal evidence-based strategy for HIV prevention. While research on PrEP has expanded rapidly, a comprehensive synthesis of the existing literature is lacking. This review systematically analyzes trends, collaborative networks, and research hotspots in PrEP through a bibliometric approach to consolidate current knowledge and inform future directions. A total of 5,273 PrEPrelated publications (1992-2025) from the Web of Science Core Collection were included, showing a 15.99% annual growth rate. The field is dominated by contributions from the United States (2,969 publications), with the University of Washington as a core institutional contributor and the Journal of Acquired Immune Deficiency Syndromes as the most prolific journal; Baeten JM emerges as a key collaborative figure. Key research hotspots include PrEP implementation, HIV prevention in men who have sex with men, adherence issues, and the development of long-acting agents (e.g., cabotegravir). Emerging trends highlight growing focus on long-acting formulations, awareness promotion, and multi-sectoral collaboration. This synthesis underscores the expanding significance of PrEP research, offering critical insights for clinicians, researchers, and policymakers. Future efforts should prioritize advancing long-acting PrEP applications, addressing barriers such as limited awareness and economic burdens, and strengthening cross-sector collaboration to maximize PrEP's role in global HIV control.","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"27 3","pages":"93-103"},"PeriodicalIF":2.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145706955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New CDC guidelines for HIV post-exposure prophylaxis. 新的疾病预防控制中心艾滋病毒暴露后预防指南。

IF 2.5 4区医学

AIDS reviews Pub Date : 2025-12-01 DOI: 10.24875/AIDSRev.M25000084

Vicente Soriano

引用次数: 0

Interventions to prevent vertical transmission of HIV: an umbrella review of systematic reviews and meta-analyses. 预防艾滋病毒垂直传播的干预措施：系统评价和荟萃分析的综合综述。

IF 2.5 4区医学

AIDS reviews Pub Date : 2025-12-01 DOI: 10.24875/AIDSRev.25000017

Keyang Ge, Xingyu Liu, Wenhua Ruan, Xingyu Wu, Zhihua Zhang

{"title":"Interventions to prevent vertical transmission of HIV: an umbrella review of systematic reviews and meta-analyses.","authors":"Keyang Ge, Xingyu Liu, Wenhua Ruan, Xingyu Wu, Zhihua Zhang","doi":"10.24875/AIDSRev.25000017","DOIUrl":"10.24875/AIDSRev.25000017","url":null,"abstract":"The aim of this umbrella review of systematic reviews and meta-analyses was to systematically consolidate and evaluate the existing evidence on interventions aimed at preventing vertical transmission of HIV, with a specific focus on assessing their efficacy and clinical applicability. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, PubMed, Cochrane Library, and Embase were searched for systematic reviews and meta-analyses (up to Feb 2025). Two reviewers independently screened studies and extracted data, including intervention outcomes. Twenty-three systematic reviews and meta-analyses were synthesized, categorizing interventions into seven types: antiretroviral therapy (ART) (n = 7), cesarean delivery (n = 1), vitamins (n = 2), vaginal disinfection (n = 2), partner engagement (n = 3), telemedicine (n = 1), and integrated approaches (n = 7). Based on this, we conclude that ART demonstrated the strongest efficacy to suppress vertical transmission of HIV. Cesarean delivery reduced transmission risk but increased postpartum morbidity. Vitamins and vaginal disinfection had minimal impact. Telemedicine may improve adherence to prevention protocols. Integrated strategies combining ART showed enhanced effectiveness in low-resource settings. In conclusion, the evidence reported in this umbrella review suggests that ART therapy supplemented by other preventive measures is an effective way to reduce the rate of mother to child transmission of HIV. Vitamin supplement and vaginal disinfection had no clear association with the risk of vertical transmission of HIV.","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"27 3","pages":"104-115"},"PeriodicalIF":2.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145706974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cloning and editing of animals for human benefit. 克隆和编辑动物以造福人类。

IF 2.5 4区医学

AIDS reviews Pub Date : 2025-12-01 DOI: 10.24875/AIDSRev.M25000086

Vicente Soriano

引用次数: 0

Integrating business management strategies to address HIV stigma and support employees in diverse workplaces. 整合企业管理战略，解决艾滋病毒污名化问题，并在不同的工作场所为员工提供支持。

IF 2.5 4区医学

AIDS reviews Pub Date : 2025-12-01 DOI: 10.24875/AIDSRev.25000009

Tingfa Zhou, Chao Hu

{"title":"Integrating business management strategies to address HIV stigma and support employees in diverse workplaces.","authors":"Tingfa Zhou, Chao Hu","doi":"10.24875/AIDSRev.25000009","DOIUrl":"10.24875/AIDSRev.25000009","url":null,"abstract":"The persistence of HIV-related stigma within workplace environments presents significant challenges to public health goals and organizational well-being. This review systematically examines the integration of business management strategies aimed at reducing stigma and enhancing support for employees affected by HIV across diverse workplace settings. Drawing from multidisciplinary perspectives, including public health, organizational behavior, and human resource management, this work identifies key intervention models, such as policy development, educational programs, leadership training, and Employee Assistance Programs. Specific attention is given to the critical role of leadership commitment, the creation of psychologically safe environments, and the implementation of multi-component, culturally sensitive interventions that address both visible and invisible dimensions of diversity. The review highlights how workplace dynamics surrounding disclosure dilemmas, confidentiality breaches, and enacted discrimination can negatively impact employee well-being and organizational productivity. Furthermore, it explores the intersectionality of HIV stigma with other marginalized identities, underscoring the necessity for targeted strategies that consider complex social identities and systemic inequities. Despite promising intervention outcomes, methodological weaknesses in existing studies - such as limited long-term evaluations and a lack of standardized measurement tools - remain pressing challenges. This review concludes by recommending evidence-based, participatory approaches that prioritize inclusive policies, robust employee support mechanisms, and stronger cross-sector collaborations to create healthier and more equitable workplaces for all employees, including those affected by HIV.","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"27 3","pages":"79-92"},"PeriodicalIF":2.5,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145706879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Why is the Bill and Melinda Gates Foundation going extinct? 为什么比尔和梅林达·盖茨基金会要消失了？

IF 2.5 4区医学

AIDS reviews Pub Date : 2025-12-01 DOI: 10.24875/AIDSRev.M25000088

Vicente Soriano

引用次数: 0