AIDS reviews最新文献_第2页

The origin of the four major focus of HTLV-1 in Latin America. 拉丁美洲 HTLV-1 四大病灶的起源。

IF 2.2 4区医学

AIDS reviews Pub Date : 2024-03-05 DOI: 10.24875/AIDSRev.M24000070

Vicente Soriano, José Manuel Ramos

引用次数: 0

Obelisks - Newly discovered virus-like particles. 方尖碑--新发现的类病毒粒子。

IF 2.2 4区医学

AIDS reviews Pub Date : 2024-03-05 DOI: 10.24875/AIDSREV.M24000069

Vicente Soriano, Víctor Moreno-Torres, Octavio Corral

引用次数: 0

Early and contemporary drivers of the HIV-1 group M pandemic. M 组艾滋病毒大流行的早期和当代驱动因素。

IF 2.2 4区医学

AIDS reviews Pub Date : 2024-03-05 DOI: 10.24875/AIDSRev.23000021

Jude P Brennan-Calland

{"title":"Early and contemporary drivers of the HIV-1 group M pandemic.","authors":"Jude P Brennan-Calland","doi":"10.24875/AIDSRev.23000021","DOIUrl":"https://doi.org/10.24875/AIDSRev.23000021","url":null,"abstract":"HIV emerged silently taking time to spread and become visible only through geographically isolated clusters of life-threatening immunodeficiency, known as AIDS since the early 80s. The clusters of infection expanded, overlapping to evolve into a pandemic that is ongoing and almost as silent. Phylogenetic analysis places the emergence of HIV-1 group M, the subtype responsible for the pandemic, in the human population more than 100 years ago. Once established, the rate and direction of spread of HIV-1 from local, to national, to contemporary pandemic proportions have varied over time and place. The literature presents many theories on the emergence and drivers of the spread of the virus over the past century. Here, historical evidence and phylogenetic models are reviewed to seek clarity on the emergence, geographic spread and key world events that mark the progression of the HIV-1 pandemic. This narrative review places particular focus on: war (both its direct and indirect affects), trade and economic expansion, changes in sexual behaviors, and public health policy. Investigating the impact of major world events and policy on the emergence and spread of HIV-1 may aid better understanding of what influences the viruses transmission dynamic. By identifying multilateral targets that influence transmission, up-scaled efforts to effectively control, if not remove, HIV-1 from the human population become a possibility. Suggestions for revisions in HIV-1 global public health policy are discussed. Refocused efforts to tackle HIV-1 transmission and replace the need to manage the pathology of this terrible disease are both ethically and economically just.","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140038578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The new face of advanced HIV infection. 晚期艾滋病毒感染的新面貌。

IF 2.2 4区医学

AIDS reviews Pub Date : 2024-03-05 DOI: 10.24875/AIDSRev.M24000068

Vicente Soriano, Pablo Barreiro

引用次数: 0

"One Health": toward an integral ecology of health. “一个健康”:迈向健康的整体生态。

IF 2.2 4区医学

AIDS reviews Pub Date : 2024-01-09 DOI: 10.24875/AIDSRev.M23000065

Vicente Soriano

引用次数: 0

Corrigendum for HIV-1 resistance and virological failure to treatment with the integrase inhibitors bictegravir, cabotegravir, and dolutegravir: a systematic literature review.

IF 1.9 4区医学

AIDS reviews Pub Date : 2024-01-01 DOI: 10.24875/AIDSRev.M25000080

José L Blanco-Arévalo, Miguel García-Deltoro, Miguel Torralba, Manuel Vélez-Díaz-Pallarés, Antonio Castro, Darío Rubio-Rodríguez, Carlos Rubio-Terrés

引用次数: 0

HIV/HBV coinfection: understanding the complex interactions and their impact on spontaneous HBV clearance, chronic liver damage, cirrhosis, and hepatocellular carcinoma. HIV/HBV 合并感染：了解复杂的相互作用及其对自发性 HBV 清除、慢性肝损伤、肝硬化和肝细胞癌的影响。

IF 2.2 4区医学

AIDS reviews Pub Date : 2024-01-01 DOI: 10.24875/AIDSRev.23000019

Jingwen Xiao, Yongzheng Zhang, Jia Wu, Xinping -Chen, Wei Zou

引用次数: 0

Acquired syphilis in the context of pre-exposure prophylaxis for HIV: a systematic review of the scientific literature. 艾滋病暴露前预防中的后天梅毒：科学文献系统回顾。

IF 1.9 4区医学

AIDS reviews Pub Date : 2024-01-01 DOI: 10.24875/AIDSRev.24000006

Nathália L Pedrosa, Patrícia M Pinheiro, Wildo N de Araújo

{"title":"Acquired syphilis in the context of pre-exposure prophylaxis for HIV: a systematic review of the scientific literature.","authors":"Nathália L Pedrosa, Patrícia M Pinheiro, Wildo N de Araújo","doi":"10.24875/AIDSRev.24000006","DOIUrl":"https://doi.org/10.24875/AIDSRev.24000006","url":null,"abstract":"The aim of this study was systematically review the acquired syphilis before and during follow-up of pre-exposure prophylaxis (PrEP) for HIV. We analyzed articles that studied PrEP users with the outcome of acquired syphilis. The eligibility criteria were studies retrieved from the United States National Library of Medicine (Pubmed), Latin American and Caribbean Health Sciences Literature (Lilacs), Embase and Scopus databases, published between 2012 and 2023, in English, Spanish or Portuguese. We performed the descriptive synthesis and quality analysis of selected studies using the Newcastle Ottawa scale or Cochrane scale. We also used random-effects models to generate pooled rate estimates for syphilis before PrEP and during follow-up. A total of 4412 studies were found and 35 were selected, all in English, and almost all with high or satisfactory quality. The review found a PrEP syphilis rate of 6.0%. A summary of three studies estimated a 2.34-fold increased risk of syphilis acquisition during PrEP, with an incidence rate of 8.89 cases/100 person-years. These findings warrant caution due to study heterogeneity. Compared to HIV-positive individuals, PrEP users exhibit potentially higher syphilis rates, particularly among those aged 33-38 years, and factors such as age ≥ 35 years, MSM status, prior sexually-transmitted infections, and longer PrEP duration (every 6 months) are associated. Future research should further investigate these PrEP-related factors contributing to heightened syphilis risk.","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"26 3","pages":"121-129"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HIV infection and esophageal cancer in Sub-Saharan Africa: a comprehensive meta-analysis. 撒哈拉以南非洲地区的艾滋病毒感染与食道癌：一项综合荟萃分析。

IF 1.9 4区医学

AIDS reviews Pub Date : 2024-01-01 DOI: 10.24875/AIDSRev.23000018

Gabriel Kamsu-Tchuente, Eugene J Ndebia

{"title":"HIV infection and esophageal cancer in Sub-Saharan Africa: a comprehensive meta-analysis.","authors":"Gabriel Kamsu-Tchuente, Eugene J Ndebia","doi":"10.24875/AIDSRev.23000018","DOIUrl":"10.24875/AIDSRev.23000018","url":null,"abstract":"Africa hosts the highest burden of esophageal cancer (49%) and HIV (60%) worldwide. It is imperative to investigate the synergistic impact of these two diseases on African populations. This study conducted an exhaustive computerized search of databases, including Medline/PubMed, Embase, Web of Science, Scopus, Cochrane library, and African Journals Online, to identify eligible studies up to October 2023. HIV infection was the exposure, esophageal cancer risk was the outcome, and healthy subjects with no cancer history served as comparators. Study quality was assessed using the Newcastle-Ottawa scale, and potential publication bias was evaluated through funnel plots and the Egger test. Meta-analyses were conducted using Stata 17.0 software and involved a thorough examination of 98,397 studies. Out of these, eight studies originating from Eastern and Southern Africa, recognized as esophageal cancer hotspots on the continent, met the eligibility criteria. The analysis revealed a non-significant association between HIV infection and esophageal cancer risk (odds ratio = 1.34 [95% confidence interval, 0.85-2.12]; with 0.26 as p-value of overall effects). The Egger test yielded a p-value of 0.2413, suggesting the absence of publication bias. In summary, this systematic review and meta-analysis indicate that there is no established causal link between HIV infection and esophageal cancer risk. However, further research is essential to delve into the potential mechanisms underlying this relationship.","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"26 1","pages":"15-22"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140292516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HIV-1 infection and the hematopoietic microenvironment.

IF 1.9 4区医学

AIDS reviews Pub Date : 2024-01-01 DOI: 10.24875/AIDSRev.24000015

Hanyun Wang, Jiliang Zou, Ying Luo, Xinping Chen, Wei Zou

{"title":"HIV-1 infection and the hematopoietic microenvironment.","authors":"Hanyun Wang, Jiliang Zou, Ying Luo, Xinping Chen, Wei Zou","doi":"10.24875/AIDSRev.24000015","DOIUrl":"https://doi.org/10.24875/AIDSRev.24000015","url":null,"abstract":"HIV-1 infection causes abnormal hematopoiesis, which is the result of the interactions among HIV-1, hematopoietic stem cells (HSCs), and hematopoietic microenvironment. However, the underlying mechanisms of abnormal hematopoiesis in HIV infection are still not completely understood. Recent studies on hematopoietic microenvironment provide new insights on HIV-1 pathogenesis. Based on these studies, we summarized the detrimental influences of HIV, mainly HIV viral proteins Gag, Tat, Gp120, and Nef, on hematopoietic microenvironment. These viral proteins interfere with the development of HSCs and hematopoiesis by affecting mesenchymal stem cells, osteoblasts, endothelial cells, and related signaling factors within the microenvironment. At the same time, we introduced the research progress of targeted therapy for HIV viral proteins and tried to solve the hard-to-correct hematopoietic abnormalities after ART by combining targeted therapy with HIV viral proteins from the direction of hematopoietic microenvironment. Our manuscript will not only enhance our understanding of the pathogenesis of HIV infection from the root of blood cell development but also have important implications for the functional cure of HIV infection.","PeriodicalId":7685,"journal":{"name":"AIDS reviews","volume":"26 4","pages":"143-150"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143456524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0