Virchows Archiv. A, Pathological anatomy and histology最新文献_第6页

The size of human coronary arteries depending on the physiological and pathological growth of the heart, the age, the size of the supplying areas and the degree of coronary sclerosis. A postmortem study. 人类冠状动脉的大小取决于心脏的生理和病理生长、年龄、供血区域的大小和冠状动脉硬化的程度。尸检研究。

Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-01-01 DOI: 10.1007/BF00430892

W Hort, H Lichti, H Kalbfleisch, F Köhler, H Frenzel, U Milzner-Schwarz

引用次数: 21

Tumor cell line characterization of a malignant histiocytosis transplanted into nude mice. 恶性组织细胞增多症移植裸鼠的肿瘤细胞系特征。

Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-01-01 DOI: 10.1007/BF00442387

M F Rousseau-Merck, F Jaubert, M A Bach, P Niaudet, D Cottreau, C Nezelof

引用次数: 1

Choriocarcinomatous change with immunocytochemically HCG-positive cells in the gastric carcinoma of the males. 男性胃癌中绒毛膜癌伴免疫细胞化学hcg阳性细胞改变。

Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-01-01 DOI: 10.1007/BF00431237

H Mori, O Soeda, T Kamano, K Tsunekawa, N Ueda, A Yoshida, R Fukunishi

{"title":"Choriocarcinomatous change with immunocytochemically HCG-positive cells in the gastric carcinoma of the males.","authors":"H Mori, O Soeda, T Kamano, K Tsunekawa, N Ueda, A Yoshida, R Fukunishi","doi":"10.1007/BF00431237","DOIUrl":"https://doi.org/10.1007/BF00431237","url":null,"abstract":"Gastric choriocarcinoma is a rare tumor and attracts interest because of its controversial pathogenesis. The present study reports a choriocarcinomatous change with immunocytochemically hCG-positive cells in the gastric carcinoma. The patients were males, one was 41 years old and the other 42 years old. The tumor of both cases consists of adenocarcinoma and choriocarcinoma. A sequential process of morphological transition of the adenocarcinoma to the choriocarcinoma can be traced. Indirect immunoperoxidase stain (PAP method) for human chorionic gonadotropin (hCG) demonstrates the localization of hCG in the syncytiotrophoblasts. Small number of cytotrophoblasts are weakly positive. None of the components of adenocarcinoma of both cases is positive for hCG. Human placental lactogen is not demonstrated in both cases. Stain for pregnancy specific beta-1 glycoprotein is weakly positive in the adenocarcinoma of one case but not in the choriocarcinoma. In one case, the concentration of hCG was 19.9 mIU/ml in the preoperative serum and decreased to 1.2 mIU/ml after gastrectomy. HCG production by gastric carcinoma was discussed with regard to possible pathogenesis of gastric choriocarcinoma.","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"396 2","pages":"141-53"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00431237","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17803314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Inverted papillomas of nasal cavity and paranasal sinuses. Ultrastructural investigations on epithelial-stromal interface. 鼻腔及副鼻窦内翻性乳头状瘤。上皮-间质界面的超微结构研究。

Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-01-01 DOI: 10.1007/BF00442391

D Katenkamp, D Stiller, K Küttner

{"title":"Inverted papillomas of nasal cavity and paranasal sinuses. Ultrastructural investigations on epithelial-stromal interface.","authors":"D Katenkamp, D Stiller, K Küttner","doi":"10.1007/BF00442391","DOIUrl":"https://doi.org/10.1007/BF00442391","url":null,"abstract":"10 cases of inverted papillomas of nasal cavity and paranasal sinuses were examined electron microscopically with particular regard to the epithelial-stromal interface. The papilloma cells were clearly demarcated from the stromal tissue by a basement membrane-like material. However, this structure mainly consisted of two or more layers, occasional breaks in the basement membrane were visible. Within the basal epithelial cells resting on the basement membrane accumulations of actin-like microfilaments could sometimes be observed. Furthermore, in the stromal tissue some myofibroblasts were present in the vicinity of the papillomatous cell complexes and capillary vessels also demonstrated several layers of basement membrane. All the changes presented here are considered to be the result of a permanent interaction between aggressive forces of papilloma cells and the defence mechanism of stromal tissue. The results allow the conclusion that inverted papillomas of nasal cavity and paranasal sinuses are true neoplasms with very low malignancy.","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"397 2","pages":"215-26"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00442391","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17941683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Cellular haemangioma. Light and electron microscopic studies of two cases. 细胞血管瘤。两例的光镜和电镜研究。

Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-01-01 DOI: 10.1007/BF00428503

K A Pasyk, W C Grabb, G W Cherry

引用次数: 4

Neurohormonal peptides and argyrophil cells in an androblastoma of the ovary. 卵巢雄性母细胞瘤中的神经激素多肽和嗜银细胞。

Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-01-01 DOI: 10.1007/BF00431245

B Sporrong, L Clase, O Ljungberg, C Wadstein

引用次数: 0

Ultrastructure of a virilizing ovarian Leydig-cell-tumor. Hilar cell tumor. 阳刚化卵巢间质细胞瘤的超微结构。肺门细胞瘤。

Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-01-01 DOI: 10.1007/BF00430890

N Schnoy

引用次数: 7

Histological changes during regression induced by retinoic acid in a transplantable rat chondrosarcoma. 维甲酸诱导可移植大鼠软骨肉瘤消退过程中的组织学变化。

Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-01-01 DOI: 10.1007/BF00428496

R Ettlin, B Galli, A Kistler

{"title":"Histological changes during regression induced by retinoic acid in a transplantable rat chondrosarcoma.","authors":"R Ettlin, B Galli, A Kistler","doi":"10.1007/BF00428496","DOIUrl":"https://doi.org/10.1007/BF00428496","url":null,"abstract":"Daily oral treatment with retinoic acid (100 mg/kg bodyweight) induced regression of a transplantable rat chondrosarcoma. In a previous biochemical investigation we have shown that the tissue breakdown is preceded by the loss of proteoglycan. The present study describes the histological changes induced by retinoic acid. A decrease in the intensity of metachromatic staining with toluidine blue was noted already after 1 day and the discoloration was almost complete after 4 days correlating with the loss of proteoglycan. Especially in the perichondrium there was a rapid proliferation of fibroblasts and monocytes. Osteoclast-like cells were missing, but tumor nodules were eroded and split up by penetrating perichondrium. After 4 days of treatment larger necrotic areas were found, initially in the center of tumor nodules only. In other areas the majority of tumorous chondroblasts survived. Tumor nodules appeared partly mesenchyma-like with some fibroblast-like cells suggesting a dedifferentiation of chondroblasts by retinoic acid. we believe that tumor regression induced by retinoic acid involved proteoglycan degradation by chondroblasts themselves and chondroclast-like activity of monocytes and fibroblasts.","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"396 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00428496","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17247238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Histologic distinction between malignant mesothelioma, benign pleural lesion and carcinoma metastasis. Evaluation of the application of morphometry combined with histochemistry and immunostaining. 恶性间皮瘤、良性胸膜病变及癌转移的组织学鉴别。形态计量学与组织化学、免疫染色相结合的应用评价。

Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-01-01 DOI: 10.1007/BF00496570

W S Kwee, R W Veldhuizen, R P Golding, H Mullink, J Stam, R Donner, M E Boon

{"title":"Histologic distinction between malignant mesothelioma, benign pleural lesion and carcinoma metastasis. Evaluation of the application of morphometry combined with histochemistry and immunostaining.","authors":"W S Kwee, R W Veldhuizen, R P Golding, H Mullink, J Stam, R Donner, M E Boon","doi":"10.1007/BF00496570","DOIUrl":"https://doi.org/10.1007/BF00496570","url":null,"abstract":"Thirty men and 7 women with malignant mesothelioma seen at the Free University Hospital from 1st January 1960 until 1st July 1981 were reviewed. The histological, histochemical and morphometrical findings are reported. These findings are compared with 25 cases of pleural metastatic carcinoma and 25 cases of reactive pleural lesions. Fourty-nine percent of malignant mesotheliomas produced hyaluronic acid, however all cases of pleural metastatic carcinomas failed to produce this substance. All cases of malignant mesothelioma were D-PAS negative while 15 cases of pleural metastatic carcinoma showed reactivity to D-PAS. All cases of malignant mesothelioma and 9 cases of metastases were CEA negative. To distinguish malignant mesothelioma from metastases it is advisable to perform the D-PAS staining first. If it is negative mesothelioma can be confirmed by showing hyaluronic acid activity. A positive CEA staining rules out mesothelioma. In our study it was shown that with these methods 18 of 37 mesotheliomas could be identified with certainty, and 22 of the 25 carcinoma metastases. Morphometrically the malignant mesotheliomas could not be distinguished from the metastases, however the reactive pleural lesions had smaller nuclei than the malignant cells with mean values below 30 mu2. In the malignant cases these values had a range from 36 to 101 mu2. In distinguishing between reactive pleural lesions and malignant mesothelioma the production of hyaluronic acid points to the malignant character of the lesion. Thus histochemistry and immunostaining are important in the distinction of malignant mesothelioma from metastases, while the value of morphometry lies mainly in the seperation of reactive lesions from malignant mesothelioma.","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"397 3","pages":"287-99"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00496570","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17250917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Stereological analyses of capillaries in muscles of dystrophic mice. 营养不良小鼠肌肉毛细血管的体视学分析。

Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-01-01 DOI: 10.1007/BF00496575

G W Atherton, M Cabric, N T James

{"title":"Stereological analyses of capillaries in muscles of dystrophic mice.","authors":"G W Atherton, M Cabric, N T James","doi":"10.1007/BF00496575","DOIUrl":"https://doi.org/10.1007/BF00496575","url":null,"abstract":"Stereological analyses of the distribution of capillaries in skeletal muscles of congenitally dystrophic mice are described and reported. Two methods are used, each based on a different mathematical model of the 3-dimensional distribution of lines in space. For these analyses specimens of extensor digitorum longus muscle from clinically affected C57BL/6Jdy2J/dy2J dystrophic mice, and from non-littermate controls, were used. The analyses were carried out on transverse and longitudinally orientated semithin sections of these muscles. Although the two methods employed are based on different mathematical models and yield results relevant to each particular model, it is clear that there is a more extensive capillary network present per unit volume of the dystrophic muscle than in control muscles. These findings are relevant to the theories which involve a vascular aetiology for muscular dystrophy. It is apparent that, in order to explore the structure of the capillary network more fully, there is a need for the development of more sophisticated stereological techniques for analysis of capillaries in skeletal muscle.","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"397 3","pages":"347-54"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00496575","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18173098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2