Virchows Archiv. A, Pathological anatomy and histology最新文献

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Peanut lectin: a useful tool for detecting Hodgkin cells in paraffin sections. 花生凝集素:一种检测霍奇金细胞石蜡切片的有效工具。
Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-08-01 DOI: 10.1007/BF00431390
P Möller
{"title":"Peanut lectin: a useful tool for detecting Hodgkin cells in paraffin sections.","authors":"P Möller","doi":"10.1007/BF00431390","DOIUrl":"https://doi.org/10.1007/BF00431390","url":null,"abstract":"<p><p>Using an extended peroxidase-antiperoxidase method receptors fot peanut lectin (PNL) can be visualized in routinely fixed paraffin embedded tissue sections. PNL binding sites are numerous in human tissue. Each tissue, however, displays its specific binding spectrum and cellular binding pattern. 35 cases of Hodgkin's disease containing all histological subtypes were examined. A prominent, constant, and characteristic binding pattern in Hodgkin- and Reed-Sternberg-cells was found. PNL is proposed as an aid for detecting these cells in diagnostic histology. It might turn out to be a very useful reagent particularly in identifying the early lesion in Hodgkin's disease in which Hodgkin cells are small and scarce.</p>","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"396 3","pages":"313-7"},"PeriodicalIF":0.0,"publicationDate":"1982-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00431390","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17806575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
The differential diagnosis of testicular germ cell tumors in theory and practice. A critical analysis of two major systems of classifiction and review of 389 cases. 睾丸生殖细胞瘤的鉴别诊断理论与实践。两大分类体系的批判性分析及389个案例的回顾。
Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-08-01 DOI: 10.1007/BF00431386
A R von Hochstetter, C E Hedinger
{"title":"The differential diagnosis of testicular germ cell tumors in theory and practice. A critical analysis of two major systems of classifiction and review of 389 cases.","authors":"A R von Hochstetter,&nbsp;C E Hedinger","doi":"10.1007/BF00431386","DOIUrl":"https://doi.org/10.1007/BF00431386","url":null,"abstract":"","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"396 3","pages":"247-77"},"PeriodicalIF":0.0,"publicationDate":"1982-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00431386","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17353067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 53
Benign pleomorpic adenoma arising in a parotid lymph node. 良性多形性腺瘤,发生于腮腺淋巴结。
Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-08-01 DOI: 10.1007/BF00431393
Y Takeda, A Suzuki
{"title":"Benign pleomorpic adenoma arising in a parotid lymph node.","authors":"Y Takeda,&nbsp;A Suzuki","doi":"10.1007/BF00431393","DOIUrl":"https://doi.org/10.1007/BF00431393","url":null,"abstract":"","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"396 3","pages":"351-6"},"PeriodicalIF":0.0,"publicationDate":"1982-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00431393","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17353069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Striae: morphological aspects of connective tissue. 条纹:结缔组织的形态学方面。
Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-08-01 DOI: 10.1007/BF00431387
M T Pieraggi, M Julian, M Delmas, H Bouissou
{"title":"Striae: morphological aspects of connective tissue.","authors":"M T Pieraggi,&nbsp;M Julian,&nbsp;M Delmas,&nbsp;H Bouissou","doi":"10.1007/BF00431387","DOIUrl":"https://doi.org/10.1007/BF00431387","url":null,"abstract":"<p><p>The study of 15 abdominal striae in women aged 25 to 57 shows important histological modifications in the skin. The collagen is fragmented and the ground substance is abundant. Fibroblasts are globular, quiescent, and lose all signs of fibrillar secretion. In the light of the recent biochemical data, our results suggest that the striae are the consequence of fibroblastic dysfunction, due to abdominal distension. Comparison with scarred and normal skin indicate that striae are a special entity belonging to the group of connective dystrophies.</p>","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"396 3","pages":"279-89"},"PeriodicalIF":0.0,"publicationDate":"1982-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00431387","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18152437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
An ultrastructural and morphometric study of bladder tumours (II). 膀胱肿瘤的超微结构和形态计量学研究(II)。
Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-08-01 DOI: 10.1007/BF00431388
A F Smith
{"title":"An ultrastructural and morphometric study of bladder tumours (II).","authors":"A F Smith","doi":"10.1007/BF00431388","DOIUrl":"https://doi.org/10.1007/BF00431388","url":null,"abstract":"<p><p>Bladder tissues from 3 groups of patients were examined, using the light and electron microscopes (LM and TEM). One group of patients had a history of well-differentiated papillary transitional cell carcinomas and specimens were taken from cytoscopically normal areas. In a second group frank papillary carcinoma was biopsied. Finally, patients with no history of urothelial tumours and a normal cytoscopic appearance were biopsied during investigations for various benign conditions and these served as controls. In tissues from the first two groups certain differences were seen when these were compared to the controls and the frequency of these was significant. Light microscopic examination of 0.5 micros toluidine blue stained sections revealed an increased number of immature, small dark cells in the superficial layer of the epithelium (P less than 0.001). Electron microscopic examination showed that in place of the characteristic asymmetric unit membrane of mature superficial cells, the surface was frequently covered with microvilli and the junctional complexes were often atypical. There was an increased number of abnormalities in the basal lamina (P less than 0.001). These features were seen in the absence of cytoscopic and light microscopic changes in three out of eight patients with a history of tumours. It is, therefore, suggested that these are the earliest detectable morphological abnormalities in the pre-neoplastic urothelium.</p>","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"396 3","pages":"291-301"},"PeriodicalIF":0.0,"publicationDate":"1982-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00431388","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18152438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Pathology of chronic vitamin E deficiency in fatal familial intrahepatic cholestasis (Byler disease). 致死性家族性肝内胆汁淤积症(拜勒病)慢性维生素E缺乏的病理研究。
Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-08-01 DOI: 10.1007/BF00431391
K Saito, S Matsumoto, T Yokoyama, M Okaniwa, S Kamoshita
{"title":"Pathology of chronic vitamin E deficiency in fatal familial intrahepatic cholestasis (Byler disease).","authors":"K Saito,&nbsp;S Matsumoto,&nbsp;T Yokoyama,&nbsp;M Okaniwa,&nbsp;S Kamoshita","doi":"10.1007/BF00431391","DOIUrl":"https://doi.org/10.1007/BF00431391","url":null,"abstract":"<p><p>A case of fatal familial intrahepatic cholestasis (Byler disease) developed a neuromuscular syndrome similar to that in experimental vitamin E deficiency and abetalipoproteinemia, and died of hepatic and cardiac failure. Serum vitamin E level was extremely low. Autopsy revealed intrahepatic cholestatic cirrhosis without obliterative lesions in the bile duct system and marked splenomegaly with splenoma-like nodules. The other pathological lesions were considered to be due to chronic vitamin E deficiency as follows:1. Mitochondrial changes especially of the hepatocyte and cardiac muscle. 2. Cardiomyopathy. 3. Myopathy. 4. Vasculopathy. 5. Systemic lipofuscinosis. 6. Lesions of the reproductive and endocrine organs. 7. Kyphoscoliosis and pes cavus. 8. Systemic neuroaxonal dystrophy with peripheral neuropathy.</p>","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"396 3","pages":"319-30"},"PeriodicalIF":0.0,"publicationDate":"1982-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00431391","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18152439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Epithelial dysplasias in chronic pancreatitis. 慢性胰腺炎的上皮发育不良。
Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-08-01 DOI: 10.1007/BF00431392
H Volkholz, M Stolte, V Becker
{"title":"Epithelial dysplasias in chronic pancreatitis.","authors":"H Volkholz,&nbsp;M Stolte,&nbsp;V Becker","doi":"10.1007/BF00431392","DOIUrl":"https://doi.org/10.1007/BF00431392","url":null,"abstract":"<p><p>The present 280 specimens of chronic pancreatitis were examined to determine the type and frequency of epithelial dysplasia of the duct system. The epitheilal dysplasias were divided into 3 degrees of severity according to cytological and histological criteria. Dysplasia was demonstrable in 40.1% of the 280 specimens. Of these 32.9% were classified as dysplasia grade I and 7.1% as dysplasia grade II. Dysplasia grade III did not occur. The epithelial proliferations were correlated with the topography, the stage of the scarring and the degree of obstruction of pancreatic secretion. An increase in dysplasia was evident in relation to the stage of the scarring and to the obstruction of secretory outflow. In correlation with the topography of the chronic pancreatitis there was the highest frequency of epithelial dysplasias in uniformly scarred glands (47.7%). Papillary and pseudopapillary hyperplasias with atypia were demonstrated in 17.9 vs. 4.5% of the cases with epithelial proliferations.</p>","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"396 3","pages":"331-49"},"PeriodicalIF":0.0,"publicationDate":"1982-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00431392","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18152440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Primary carcinoid tumor of the ear. 原发性耳类癌。
Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-08-01 DOI: 10.1007/BF00431394
S Inoue, K Tanaka, S Kannae
{"title":"Primary carcinoid tumor of the ear.","authors":"S Inoue,&nbsp;K Tanaka,&nbsp;S Kannae","doi":"10.1007/BF00431394","DOIUrl":"https://doi.org/10.1007/BF00431394","url":null,"abstract":"","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"396 3","pages":"357-63"},"PeriodicalIF":0.0,"publicationDate":"1982-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00431394","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18152441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Transplantation of ACTH-secreting pituitary tumor cells in athymic nude mice. 促肾上腺皮质激素垂体肿瘤细胞在胸腺裸鼠体内的移植。
Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-08-01 DOI: 10.1007/BF00431389
C K Leung, J A Paterson, Y Imai, R P Shiu
{"title":"Transplantation of ACTH-secreting pituitary tumor cells in athymic nude mice.","authors":"C K Leung,&nbsp;J A Paterson,&nbsp;Y Imai,&nbsp;R P Shiu","doi":"10.1007/BF00431389","DOIUrl":"https://doi.org/10.1007/BF00431389","url":null,"abstract":"<p><p>Chronic excess of glucocorticoids results in Cushing's syndrome in humans. A common cause of excess cortisol secretion is the presence of an adrenocorticotropin secreting pituitary tumor which stimulates the adrenal cortex to produce excess glucocorticoids. ACTH-secreting AtT-20 mouse pituitary cells transplanted subcutaneously in oestrogenized athymic nude mice form tumors rapidly. Six weeks after receiving the tumor transplants, the mice weighed 45% more than normal mice due to the increase in body fat. The tumor-bearing mice exhibit the familial \"buffalo hump\" appeaance due to the abnormal distribution of body fat. The adrenal glands of the tumor-bearing animals are enlarged due to hypertrophy of the zona fasciculata. The foamy looking fasciculata cells in normal mice were converted to dense, eosinophilic cells in the tumor-bearing mice. Transplantation of normal pituitary glands to athymic nude mice with or without oestrogen treatment did not produce these morphological changes. The experimental model described here may be useful for future studies of Cushing's syndrome.</p>","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"396 3","pages":"303-12"},"PeriodicalIF":0.0,"publicationDate":"1982-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00431389","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17353068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Malignant fibrous histiocytoma arising in a recurrent chordoma. Case report and electron microscopic findings. 复发性脊索瘤引起的恶性纤维组织细胞瘤。病例报告及电镜检查结果。
Virchows Archiv. A, Pathological anatomy and histology Pub Date : 1982-01-01 DOI: 10.1007/BF00496567
M Makek, H J Leu
{"title":"Malignant fibrous histiocytoma arising in a recurrent chordoma. Case report and electron microscopic findings.","authors":"M Makek,&nbsp;H J Leu","doi":"10.1007/BF00496567","DOIUrl":"https://doi.org/10.1007/BF00496567","url":null,"abstract":"<p><p>We present the case of a sacrococcygeal chordoma which recurred 15 years after the radical removal as a soft tissue tumor in the gluteal musculature. This tumor consisted of two parts: a chordoma without symptoms of aggressive cellular proliferation and a malignant fibrous histiocytoma. During the following 4 years several local recurrences of the malignant fibrous histiocytoma occurred in the gluteal musculature. The patient finally died of lung metastases. No chordoma tumor tissue was found in the lungs, in the gluteal musculature or in the sacrococcygeal bone area. Histology including electron microscopy revealed no proof of a transition of chordoma into malignant fibrous histiocytoma. It must be assumed that the secondary soft tissue tumor originated from residual chordoma cells which were implanted during the operation of the primary tumor. It remains unclear whether the malignant fibrous histiocytoma arose from mesenchymal stromal cells within the chordoma or directly from primitive neuroectodermal chorda cells which possess the ability to differentiate into a variety of cell types including mesenchymal cells.</p>","PeriodicalId":76799,"journal":{"name":"Virchows Archiv. A, Pathological anatomy and histology","volume":"397 3","pages":"241-50"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00496567","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17359114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
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