Tropenmedizin und Parasitologie最新文献_第6页

The occurrence of toxoplasma gondii in saliva. 唾液中刚地弓形虫的发生。

Tropenmedizin und Parasitologie Pub Date : 1984-03-01

A Terragna, N Morandi, A Canessa, C Pellegrino

引用次数: 0

Schistosoma mansoni: loss of the ability of schistosomula to bind mouse complement following intravenous injection into mice. 曼氏血吸虫:静脉注射到小鼠体内后，失去了血吸虫结合小鼠补体的能力。

Tropenmedizin und Parasitologie Pub Date : 1984-03-01

A Ruppel, U Rother, H J Diesfeld

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The effect of experimental Onchocerca infections on the fecundity and oviposition of laboratory reared Simulium sp. (Diptera, Simuliidae). 实验盘尾丝虫病对实验室饲养拟蝇产卵和繁殖能力的影响。

Tropenmedizin und Parasitologie Pub Date : 1984-03-01

P J Ham, A J Banya

{"title":"The effect of experimental Onchocerca infections on the fecundity and oviposition of laboratory reared Simulium sp. (Diptera, Simuliidae).","authors":"P J Ham, A J Banya","doi":"","DOIUrl":"","url":null,"abstract":"Two species of Simulium were used to examine the effect of experimental Onchocerca lienalis infections on their fecundity and oviposition rates. S. ornatum s.l. was chosen as a natural vector of bovine onchocerciasis in Britain, and S. lineatum was selected because of its suitability as an experimental model for oviposition studies. Infection was either by feeding with blood containing microfilariae, or by intrathoracic injection of the parasites. Using the blood feeding technique, reductions in the fecundity of S. lineatum were observed at rates of 21 to 76%, depending on the concentration of parasites. A reduction of 21% in the fecundity of S. ornatum s.l. (P less than 0.05) was achieved when flies were fed on microfilariae at 69,000 per ml. Although individual flies feeding on infected blood may take as much as those in control groups, the feeding rates were reduced in several instances. S. lineatum also showed a depression of oviposition rate when infected by O. linenalis larvae. Fecundity was also significantly reduced when the route of infection was intrathoracic. Reductions for S. lineatum depended on the inoculum, but were either 36% (10 microfilariae per fly) or 54% (50 microfilariae per fly). S. ornatum s.l. showed a 13% reduction in fecundity when given 20 microfilariae per fly. It was concluded that similar experimental studies could be usefully performed with S. damnosum s.l. infected with O. volvulus microfilariae.","PeriodicalId":76764,"journal":{"name":"Tropenmedizin und Parasitologie","volume":"35 1","pages":"61-6"},"PeriodicalIF":0.0,"publicationDate":"1984-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17765704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The action of diethylcarbamazine on the skin-dwelling microfilariae of Monanema globulosa (Nematoda: Filarioidea) in rodents. 二乙基卡马嗪对啮齿动物皮肤球形单胞线虫(线虫纲:丝状总科)微丝虫的作用。

Tropenmedizin und Parasitologie Pub Date : 1984-03-01

A E Bianco, D A Denham

{"title":"The action of diethylcarbamazine on the skin-dwelling microfilariae of Monanema globulosa (Nematoda: Filarioidea) in rodents.","authors":"A E Bianco, D A Denham","doi":"","DOIUrl":"","url":null,"abstract":"Diethylcarbamazine (DEC) administered orally to jirds and striped mice (300 mg/kg for five days) was effective against the microfilariae of Monanema globulosa in experimental infections. Based on the small numbers of animals used in this trial, it is questionable whether the drug had significant activity against the adult worms in pulmonary arteries. Densities of microfilariae in the ears (mf/mg) fell by 80-100% of pretreatment levels over a four week period following treatment. There was no apparent action of the developing embryos in utero, and in some rodents densities of microfilariae in the skin returned to 73-88% of pretreatment levels within 70 days. No microfilariae were detected in the blood or urine during treatment. Twenty-four hours after the first dose of DEC, many of the microfilariae in the dermis became surrounded by a local infiltration of neutrophils, eosinophils and histiocytes. Cellular reactions were accompanied by an acute pruritus in rodents, as indicated by scratching and distress exhibited soon after treatment: No reactions to microfilariae were seen in untreated rodents. Similarities between this response and the Mazzotti reaction induced by DEC in human onchocerciasis indicate that M. globulosa may be of value as a rodent model to study adverse drug reactions in Onchocerca volvulus infections.","PeriodicalId":76764,"journal":{"name":"Tropenmedizin und Parasitologie","volume":"35 1","pages":"53-7"},"PeriodicalIF":0.0,"publicationDate":"1984-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17763968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Isolation of phospholipase A1 from Trypanosoma brucei. 布鲁氏锥虫磷脂酶A1的分离。

Tropenmedizin und Parasitologie Pub Date : 1984-03-01

P N Hambrey, C M Forsberg, A Mellors, I R Tizard, G M Werchola

引用次数: 0

Natural interspecific hybridisation of simulium sanctipauli s.l. with Simulium squamosum and Simulium yahense (Diptera: Simuliidae). 拟合蝇与拟合蝇、拟合蝇的种间自然杂交(双翅目:拟合蝇科)。

Tropenmedizin und Parasitologie Pub Date : 1984-03-01

R J Post

引用次数: 0

[Behavior of a Trypanosoma brucei strain (STIB 348C) in mice. 3. Histopathological findings in the terminal stage of infection]. 布鲁氏锥虫菌株(STIB 348C)在小鼠体内的行为。3.感染终末期的组织病理学结果]。

Tropenmedizin und Parasitologie Pub Date : 1983-12-01

W Büngener

{"title":"[Behavior of a Trypanosoma brucei strain (STIB 348C) in mice. 3. Histopathological findings in the terminal stage of infection].","authors":"W Büngener","doi":"","DOIUrl":"","url":null,"abstract":"Histopathological findings in the terminal stage of the infection of mice and rats with different variants of the Trypanosoma brucei brucei stock are described. Mice infected with mild variants showed after 12-149 days intense trypanosome colonization of the interstitial connective tissue, especially of the heart muscle, pancreas and choroid plexus, with severe tissue destructions, especially in the pancreas. With longer duration of the infection, round cell infiltrations of the leptomeninx and around intracerebral vessels developed. The alterations were the same in animals dying with high and low parasitemias. Some animals died with continuous bleeding from the tip of the tail, with serious effusions and massive edema or with generalized bacterial infection. The lymphatic organs showed intense reactive alterations, trypanosomes were only rarely found in lymph nodes. In the liver large fields of lymphatic and myeloid cells were seen, sometimes necroses developed. The kidneys showed marked deposition of eosinophilic material in the glomeruli and precipitation of proteinaceous material in dilated tubules. - Rats infected with mild trypanosomes exhibited intense colonization of the heart by trypanosomes, in some places many trypanosomes in lymph nodes, few trypanosomes in the pancreas. They died after a long phase of high parasitemia.--After infection with virulent parasites which killed the animals with high parasitemia in a few days, mice and rats had single small foci of trypanosome colonization of the interstitial connective tissue of heart, pancreas and choroid plexus as well as of the loose connective tissue in the hilum of the kidney and around lymph nodes.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":76764,"journal":{"name":"Tropenmedizin und Parasitologie","volume":"34 4","pages":"213-9"},"PeriodicalIF":0.0,"publicationDate":"1983-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17720781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human serum proteins indicative for the nutritional status and serum proteinase inhibitors in uncomplicated falciparum malaria. 指示无并发症恶性疟疾患者营养状况的人血清蛋白和血清蛋白酶抑制剂。

Tropenmedizin und Parasitologie Pub Date : 1983-12-01

F P Schelp, T Harinasuta, D Bunnag, D Böhning, V Supawan, S Deininger, P Pongpaew

{"title":"Human serum proteins indicative for the nutritional status and serum proteinase inhibitors in uncomplicated falciparum malaria.","authors":"F P Schelp, T Harinasuta, D Bunnag, D Böhning, V Supawan, S Deininger, P Pongpaew","doi":"","DOIUrl":"","url":null,"abstract":"The serum proteins supposed to be indicative of the nutritional status, albumin, prealbumin and transferrin, as well as the serum proteinase inhibitors alpha 1-protease inhibitor (alpha 1-antichymotrypsin (Ach) and alpha 2-macroglobulin (alpha 2M) were measured in 14 Thai males suffering from uncomplicated falciparum malaria on the day of admission and after treatment with mefloquin on the 2nd, 28th and 63rd day. The same serum proteins had been determined from 31 healthy Thai males. Upon admission albumin and prealbumin concentrations had been lower and Ach higher in malaria patients compared with healthy Thai males. A significantly higher alpha 1 PI value was observed on the day of admission compared with the 28th day of the malaria patients. Only on the day of admission and only for the patients was a statistically significant negative linear regression found for albumin and prealbumin with Ach and a positive correlation for prealbumin with alpha 2 M as well as for albumin and transferrin correlated with alpha 1 PI. In well-nourished malaria patients the synthesis of the \"acute phase reactants\", alpha 1 PI and Ach, might be enhanced and in a reverse relationship the synthesis of albumin, pre-albumin and transferrin depressed.","PeriodicalId":76764,"journal":{"name":"Tropenmedizin und Parasitologie","volume":"34 4","pages":"244-7"},"PeriodicalIF":0.0,"publicationDate":"1983-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17263581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A selective liquid medium for primary isolation of South American Leishmanias. 初步分离南美利什曼原虫的选择性液体培养基。

Tropenmedizin und Parasitologie Pub Date : 1983-12-01

J C Palomino, H Guerra, H Lumbreras

引用次数: 0

The effect of Trypanosoma brucei infection on local and systemic antibody responses of rats to Nippostrongylus brasiliensis. 布鲁氏锥虫感染对大鼠对巴西尼波圆线虫局部和全身抗体反应的影响。

Tropenmedizin und Parasitologie Pub Date : 1983-12-01

H Wedrychowicz, J M Maclean, P H Holmes

{"title":"The effect of Trypanosoma brucei infection on local and systemic antibody responses of rats to Nippostrongylus brasiliensis.","authors":"H Wedrychowicz, J M Maclean, P H Holmes","doi":"","DOIUrl":"","url":null,"abstract":"Adult Hooded Lister rats were given 5000 Nippostrongylus brasiliensis larvae on day 3 or 7 after infection with Trypanosoma brucei and a second dose of 5000 nematode larvae 28 days later. A similar number of rats was infected only with N. brasiliensis larvae. Comparison of antibody levels in serum and the respiratory and alimentary tracts showed that T. brucei infection influenced both systemic and local antibody responses of rats to N. brasiliensis antigens. After primary infection systemic antibody responses were mainly impaired, the level of suppression depending upon the interval between trypanosome and nematode infections. Anamnestic responses were diminished in both antibody systems. The number of worms reaching the small intestine of T. brucei parasitised rats after primary infection was twice- and after reinfection three-times higher than in rats subjected to nematode infections alone. However, adult nematode expulsion was not delayed. The results suggest that N. brasiliensis infection causes a multiantigenic stimulation of both systemic and local humoral responses of the host. Furthermore, they indicate that depression of systemic antibody responses may enhance worm establishment.","PeriodicalId":76764,"journal":{"name":"Tropenmedizin und Parasitologie","volume":"34 4","pages":"207-12"},"PeriodicalIF":0.0,"publicationDate":"1983-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17721984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0