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American journal of respiratory and critical care medicine最新文献

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Baseline Membrane Thickness in Asthma: Where Type-2 Inflammation Meets Remodeling? 哮喘的基线膜厚度：2型炎症与重塑的关系？
IF 24.7 1区 医学
American journal of respiratory and critical care medicine Pub Date : 2025-06-30 DOI: 10.1164/rccm.202505-1106le
James Melhorn,Simon Couillard
{"title":"Baseline Membrane Thickness in Asthma: Where Type-2 Inflammation Meets Remodeling?","authors":"James Melhorn,Simon Couillard","doi":"10.1164/rccm.202505-1106le","DOIUrl":"https://doi.org/10.1164/rccm.202505-1106le","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":"6 1","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144521221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On Not Betraying Our Trainees, Especially Now. 不要背叛我们的学员，尤其是现在。
IF 24.7 1区 医学
American journal of respiratory and critical care medicine Pub Date : 2025-06-26 DOI: 10.1164/rccm.202505-1236vp
Theodore J Iwashyna
{"title":"On Not Betraying Our Trainees, Especially Now.","authors":"Theodore J Iwashyna","doi":"10.1164/rccm.202505-1236vp","DOIUrl":"https://doi.org/10.1164/rccm.202505-1236vp","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":"26 1","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144488297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Addressing Knowledge Gaps in the Early Detection of Bronchiolitis Obliterans Syndrome After Hematopoietic Cell Transplantation. An Official American Thoracic Society Research Statement. 解决造血细胞移植后闭塞性细支气管炎综合征早期检测的知识空白。美国胸科学会官方研究报告。
IF 24.7 1区 医学
American journal of respiratory and critical care medicine Pub Date : 2025-06-26 DOI: 10.1164/rccm.202506-1352st
Guang-Shing Cheng,Ajay Sheshadri,Jane Turner,Kirsten M Williams,Joe L Hsu,Thomas Agoritsas,M Haider Ali,Louise Bondeelle,Guy Bouguet,Pascal Chanez,Kenneth R Cooke,Craig J Galban,Samuel Goldfarb,Teal S Hallstrand,Sarah Johnson,David C L Lam,David Michonneau,David N O'Dwyer,Sophie Paczesny,Husham Sharifi,Jamie L Todd,Daniel Wolff,Hemang Yadav,Gregory A Yanik,Anne Bergeron
{"title":"Addressing Knowledge Gaps in the Early Detection of Bronchiolitis Obliterans Syndrome After Hematopoietic Cell Transplantation. An Official American Thoracic Society Research Statement.","authors":"Guang-Shing Cheng,Ajay Sheshadri,Jane Turner,Kirsten M Williams,Joe L Hsu,Thomas Agoritsas,M Haider Ali,Louise Bondeelle,Guy Bouguet,Pascal Chanez,Kenneth R Cooke,Craig J Galban,Samuel Goldfarb,Teal S Hallstrand,Sarah Johnson,David C L Lam,David Michonneau,David N O'Dwyer,Sophie Paczesny,Husham Sharifi,Jamie L Todd,Daniel Wolff,Hemang Yadav,Gregory A Yanik,Anne Bergeron","doi":"10.1164/rccm.202506-1352st","DOIUrl":"https://doi.org/10.1164/rccm.202506-1352st","url":null,"abstract":"BACKGROUNDBronchiolitis obliterans syndrome (BOS) is a late onset noninfectious pulmonary complication of allogeneic hematopoietic cell transplantation (HCT) that is often diagnosed in advanced stage with severe lung impairment. Increasing utilization of HCT for the treatment of hematologic diseases worldwide translates to an increasing burden of BOS, particularly for the community pulmonologist. Early recognition of BOS, which offers the best opportunity to mitigate morbidity and mortality, is hampered by incomplete knowledge of the clinical course and disease process. The goal of this research statement is to survey our current understanding of BOS and to define the research agenda for the early detection of BOS.METHODSWe convened a multidisciplinary panel that included community representatives for an in-depth survey of the published literature followed by an online workshop.RESULTSMajor knowledge gaps were identified within interrelated themes of natural history and pathogenesis, risk factors, and the clinical diagnostic approach.CONCLUSIONSThis statement reflects the detailed assessment of identified knowledge gaps with associated key research questions, as well as a proposed research roadmap to stimulate cross-disciplinary collaborations from pre-clinical to clinical investigations.","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":"243 1","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144488299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Factors for Stress-related UGIB: More than a Gut Feeling. 压力相关UGIB的风险因素：不仅仅是直觉。
IF 24.7 1区 医学
American journal of respiratory and critical care medicine Pub Date : 2025-06-26 DOI: 10.1164/rccm.202504-0977ed
Robert MacLaren
{"title":"Risk Factors for Stress-related UGIB: More than a Gut Feeling.","authors":"Robert MacLaren","doi":"10.1164/rccm.202504-0977ed","DOIUrl":"https://doi.org/10.1164/rccm.202504-0977ed","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":"17 1","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144488295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Mirage of Individualized Therapy in the United States: Barriers in Pulmonary Hypertension Due to Sickle Cell Disease & Sarcoidosis. 美国个体化治疗的海市蜃楼：镰状细胞病和结节病引起的肺动脉高压的障碍。
IF 24.7 1区 医学
American journal of respiratory and critical care medicine Pub Date : 2025-06-26 DOI: 10.1164/rccm.202411-2126vp
Steven J Cassady,Mark T Gladwin
{"title":"The Mirage of Individualized Therapy in the United States: Barriers in Pulmonary Hypertension Due to Sickle Cell Disease & Sarcoidosis.","authors":"Steven J Cassady,Mark T Gladwin","doi":"10.1164/rccm.202411-2126vp","DOIUrl":"https://doi.org/10.1164/rccm.202411-2126vp","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":"17 1","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144488298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DNA Damage in Pulmonary Arterial Hypertension and Veno-occlusive Disease - FANCL as Dual Rescue? 肺动脉高压和静脉闭塞性疾病的DNA损伤——FANCL作为双重救助？
IF 24.7 1区 医学
American journal of respiratory and critical care medicine Pub Date : 2025-06-26 DOI: 10.1164/rccm.202505-1114ed
Oleg Pak,Norbert Weissmann,Natascha Sommer
{"title":"DNA Damage in Pulmonary Arterial Hypertension and Veno-occlusive Disease - FANCL as Dual Rescue?","authors":"Oleg Pak,Norbert Weissmann,Natascha Sommer","doi":"10.1164/rccm.202505-1114ed","DOIUrl":"https://doi.org/10.1164/rccm.202505-1114ed","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":"17 1","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144488302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Peek into Pulmonary Hypertension Through the Plasma Proteome. 通过血浆蛋白质组研究肺动脉高压。
IF 24.7 1区 医学
American journal of respiratory and critical care medicine Pub Date : 2025-06-26 DOI: 10.1164/rccm.202505-1063ed
Samisubbu R Naidu,Ankit A Desai
{"title":"A Peek into Pulmonary Hypertension Through the Plasma Proteome.","authors":"Samisubbu R Naidu,Ankit A Desai","doi":"10.1164/rccm.202505-1063ed","DOIUrl":"https://doi.org/10.1164/rccm.202505-1063ed","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":"183 1","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144488300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Environmental Sustainability in Intensive Care: From Awareness to Action. 重症监护中的环境可持续性：从意识到行动。
IF 24.7 1区 医学
American journal of respiratory and critical care medicine Pub Date : 2025-06-26 DOI: 10.1164/rccm.202411-2220cp
Melany Gaetani,Marko Balan,Srinivas Murthy,Christina Maratta
{"title":"Environmental Sustainability in Intensive Care: From Awareness to Action.","authors":"Melany Gaetani,Marko Balan,Srinivas Murthy,Christina Maratta","doi":"10.1164/rccm.202411-2220cp","DOIUrl":"https://doi.org/10.1164/rccm.202411-2220cp","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":"22 1","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144488296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Moving from Observation to Explanation: Probing the Biology of Heterogeneity of Treatment Effects. 从观察到解释：探讨治疗效果异质性的生物学。
IF 24.7 1区 医学
American journal of respiratory and critical care medicine Pub Date : 2025-06-26 DOI: 10.1164/rccm.202505-1299ed
Neha A Sathe,Nadir Yehya,Pavan K Bhatraju
{"title":"Moving from Observation to Explanation: Probing the Biology of Heterogeneity of Treatment Effects.","authors":"Neha A Sathe,Nadir Yehya,Pavan K Bhatraju","doi":"10.1164/rccm.202505-1299ed","DOIUrl":"https://doi.org/10.1164/rccm.202505-1299ed","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":"653 1","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144488301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modeling CF Patient-Specific Responses to CFTR Modulators Using Human Induced Pluripotent Stem Cells. 利用人诱导多能干细胞模拟CF患者对CFTR调节剂的特异性反应。
IF 24.7 1区 医学
American journal of respiratory and critical care medicine Pub Date : 2025-06-23 DOI: 10.1164/rccm.202502-0467rl
Kayshani R Kanagarajah,Ming Jia Michael Wu,Timothy Lam,Henry Quach,Rasha Salih,Krista Antonio,Theo J Moraes,Felix Ratjen,Christine E Bear,Amy P Wong
{"title":"Modeling CF Patient-Specific Responses to CFTR Modulators Using Human Induced Pluripotent Stem Cells.","authors":"Kayshani R Kanagarajah,Ming Jia Michael Wu,Timothy Lam,Henry Quach,Rasha Salih,Krista Antonio,Theo J Moraes,Felix Ratjen,Christine E Bear,Amy P Wong","doi":"10.1164/rccm.202502-0467rl","DOIUrl":"https://doi.org/10.1164/rccm.202502-0467rl","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":"45 1","pages":""},"PeriodicalIF":24.7,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144370092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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