W Dobryszycka, M Warwas, J Osada, K Jacyszyn, D Biala, J Lembas, M Wozniak, K Lemanska, J Kulpa, H Owczarek
{"title":"Biochemical studies on populations with long- or short-term exposure to environmental pollution.","authors":"W Dobryszycka, M Warwas, J Osada, K Jacyszyn, D Biala, J Lembas, M Wozniak, K Lemanska, J Kulpa, H Owczarek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Three groups of populations were studied: I. living for about 10 years, II. living for about 3 years near copper smelteries, and III. living in rural area, far from any source of air pollution. Lead content in blood was found to be 182.0 and copper 274.6 microgram/100 ml for group I, Pb - 69.2 and Cu - 253.3 microgram/100 ml for group II, and Pb - 43.8 and Cu - 143.3 microgram/100 ml for group III. Inhibition of glycolytic cycle enzymes and delta-aminolevulinic acid dehydratase was proportional to the duration of exposure to environmental pollution. Ceruloplasmin concentration in serum, as well as serum and red cells aminotransferases activities, were increased in group II and decreased in group I, suggesting certain mechanism of adaptation.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"7 1-2","pages":"23-7"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12083129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A study on the physiology and biochemistry of the flank gland of the musk shrew, Suncus murinus viridescens (Blyth).","authors":"M Balakrishnan, K M Alexander","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The flank gland becomes functional by about the 9th day after parturition and exhibits a secretory rhythm with a nocturnal peak. Lipids constitute the major biochemical constituent of the total solids. Relatively, cholesterol, ascorbic acid and alkaline phosphatase contents of the flank gland were much higher than those of the control skin samples. Disc electrophoretic pattern of glandular secretion reveal that male and female shrews have 6 & 8 protein fractions respectively. The flank gland was observed to be androgen-dependent in male shrews. Ethological observations indicate that secretions of this gland are used for marking purposes.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"7 1-2","pages":"13-21"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12083128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Elements of timbre perception.","authors":"J W Hall","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An evaluative review of the timbre perception literature is made. Attention is given to physical, psychological, and physiological factors involved in the perception of controlled musical and speech stimuli. Timbre perception is considered to be a complex process involving the synthesis of three main elements: the overtone structure of the stimulus, a temporal integration of acoustical events, and the context of the stimulation.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"7 3-4","pages":"43-51"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11558574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Jacobs, G Anderson, S Bailey, J Ottaviano, V McCarthy
{"title":"Neurophysiological correlates of acupuncture: limbic and thalamic responses to analgesic studies in non-human primates.","authors":"S Jacobs, G Anderson, S Bailey, J Ottaviano, V McCarthy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Single unit activity from chronically implanted squirrel monkeys was analyzed to evaluate the effect of acupuncture stimulation on limbic and thalamic structures associated with pain. Extracellular recordings and computer-generated interspike interval histograms (ISIH) were obtained from n. parafasicularis and n. ventralis posteromedialis of the thalamus and the laternal septum, basal amygdala and anterior cigulate cortex. Thalamic activity remained unchanged while limibc units demonstrated statistically significant alterations in both cell firing rate and the ISIH in response to acupuncture stimulation. Although pain thresholds in response to tooth pulp stimulation were increased by morphine (37-51% +/- 2.1), acupuncture proved totally ineffective. This may be interpreted as a selective response to acupuncture in CNS structures primarily concerned with the affective component of pain.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"7 3-4","pages":"37-42"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11625089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of some antithrombogenic drugs on the polyethylene-Krebs solution interface.","authors":"P J Aragon, C Gottberg","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of some antithrombogenic drugs on the streaming potentials found in the interface polyethylene-Krebs solutions were studied. Drugs such as dypiramidol, heparin and apsirine were tested in different concentrations. The variation of streaming potentials with the pressure gradient (fluid velocity) were experimentally determined, surface charge densities and degrees of coverage calculated. Surface charge densities were in the order of 4 X 10(-10) C/cm2, with very low degrees of surface coverage.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"7 1-2","pages":"7-11"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12081700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Search in short-term memory during inhalation of a general anesthetic in man.","authors":"N Adam, G I Collins","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Effects of controlled subanesthetic concentrations of enflurane on short-term memory functions were studied in male volunteers. Short-term memory processes were assessed through a search task: A series of digits, words, or familiar pictures, was visually presented, followed by a test digit which in half the trials was part of the series, and in half of the trials it was not. The subject responded by a press on one of two switches signalling 'yes' or 'no' accordingly. Memory set size varied between 1 to 11 for digits and 1 to 8 for words and pictures. Enflurane in air was delivered through a non-rebreathing system. Low concentrations of enflurane did not change the slope of the search function, but increased the intercept by few hundred milliseconds. This was interpreted to indicate anesthetic effect on the cognitive processes reflected in the intercept, that is, stimulus reception and evaluation and response variables. No effect was observed on retrieval time from the short-term store.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"7 3-4","pages":"53-8"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11816881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cutaneous cross-modal interactions: variations in punctate pressure sensitivity with skin surface temperature.","authors":"S Johnstone, A M Prestrude","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We determined the effects of adapting the skin surface to temperatures 3 degreees C, 8 degrees C, or 12 degrees C above and below physiological zero for 0, 2, 5, 10, 15, or 30 min on punctate pressure sensitivity. Temperatures above physiological zero reduced punctate pressure sensitivity and temperatures below physiological zero enhanced punctate pressure sensitivity. As the skin adapted to warmth, punctate pressure sensitivity increased suggesting a cross modal adaptation effect, however there was no indication of a decrease in punctate pressure sensitivity as the skin adapted to cooling. The results are considered to be consonant with a system of mechanoreceptors which also respond to temperature changes and a system in which there are points of convergence in the somesthetic pathways at which pressure and temperature information interact and are integrated.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"7 1-2","pages":"29-35"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12083130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Calculation of intratumor temperature in a heated superficial tumor.","authors":"A Yerushalmi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Measurements of intratumor temperature build-up in locally heated superificial tumor in the footpads of mice were analyzed. The intratumor temperature rise was found to consist of two slopes before the temperature reached a steady state. An empirical equation was developed, allowing a close estimate of the intratumor steady state temperature.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"6 1-2","pages":"35-9"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11407429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hyperinsulinemia: effects on body weight, obesity and motivated behaviors.","authors":"H E Marks, C Davison","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Five experiments were performed to evaluate the physiological and behavioral similarities between lesions of the ventromedial hypothalamus (VMH) and injection-produced hyperinsulinemia. It was found that the rate of weight gain and fat deposition in both adult and weanling rats was essentially the same for both VMH and hyperinsulinemic rats. Measures of activity and taste preference measures yielded no differences between hyperinsulinemic rats and intact rats. Electric shock thresholds revealed a decrease in reactivity for hyperinsulinemic rats compared to intact rats. A hypothesis was suggested in which a combination of hypophysectomy, gonadectomy, and hyperinsulinemia might produce most of the physiological effects seen with VMH lesions. It was also suggested that since these physiological alterations radically modify the organism's internal environment, the behavioral effects of VMH lesions may be the results of the attempts of a brain-damaged animal to maintain new physiological conditions.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"6 1-2","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12200187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of general anesthetics on search in memory in man.","authors":"N Adam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recovery of search functions in long-term memory following several hours of anesthesia was studied on human volunteers. Verbal as well as visual search was assessed. The anesthetics used, fluroxene and halothane, slowed down considerably the verbal search for the first few hours following anesthesia, but had very little effect on the following day. No effect was observed a week later. Visual search was not affected at all, in accordance with previous findings indicating a selective effect of low concentrations of inhalation anesthetics on verbal memory.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"6 1-2","pages":"29-34"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11238332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}