Biochemical studies on populations with long- or short-term exposure to environmental pollution.

T.-I.-T. journal of life sciences Pub Date : 1977-01-01
W Dobryszycka, M Warwas, J Osada, K Jacyszyn, D Biala, J Lembas, M Wozniak, K Lemanska, J Kulpa, H Owczarek
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Abstract

Three groups of populations were studied: I. living for about 10 years, II. living for about 3 years near copper smelteries, and III. living in rural area, far from any source of air pollution. Lead content in blood was found to be 182.0 and copper 274.6 microgram/100 ml for group I, Pb - 69.2 and Cu - 253.3 microgram/100 ml for group II, and Pb - 43.8 and Cu - 143.3 microgram/100 ml for group III. Inhibition of glycolytic cycle enzymes and delta-aminolevulinic acid dehydratase was proportional to the duration of exposure to environmental pollution. Ceruloplasmin concentration in serum, as well as serum and red cells aminotransferases activities, were increased in group II and decreased in group I, suggesting certain mechanism of adaptation.

长期或短期暴露于环境污染人群的生化研究。
研究了三组人口:1 .生活约10年;在铜冶炼厂附近生活了大约3年;生活在远离任何空气污染源的农村地区。第一组血铅为182.0微克/100毫升,铜为274.6微克/100毫升;第二组血铅为69.2微克/100毫升,铜为253.3微克/100毫升;第三组血铅为43.8微克/100毫升,铜为143.3微克/100毫升。糖酵解循环酶和δ氨基乙酰丙酸脱水酶的抑制与暴露于环境污染的时间成正比。血清铜蓝蛋白浓度、血清和红细胞转氨酶活性均在ⅱ组升高、ⅰ组降低,提示有一定的适应机制。
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