T.-I.-T. journal of life sciences最新文献

{"title":"Innovative technology and established partnerships-a recipe for rapid adaptability under emerging pandemic conditions.","authors":"Shamir Mukhi, Melanie Laffin-Thibodeau, Tim Beattie","doi":"10.14745/ccdr.v49i05a04","DOIUrl":"10.14745/ccdr.v49i05a04","url":null,"abstract":"<p><strong>Background: </strong>Aided by a collaborative partnership dating back to 2011, the Canadian Network for Public Health Intelligence (CNPHI) and the Canadian Paediatric Surveillance Program (CPSP) quickly undertook substantial enhancements to the CPSP's data collection instruments on the CNPHI platform to characterize the impacts of the coronavirus disease 2019 (COVID-19) on children and youth in Canada. Faced with an emerging public health threat with impacts yet unknown, the objective of the intervention was to rapidly complete enhancements to existing data collection and analytical tools to enable the CPSP's ability to characterize the impacts of COVID-19 in Canadian children and youth.</p><p><strong>Intervention: </strong>Reporting frequency from CPSP's network of paediatric practitioners was increased from monthly to weekly, and the flexibility of detailed case data collection was substantially enhanced using complex survey instruments, interactively designed using CNPHI's Web Data technology. To ensure their data collection proceeded along all required lines of surveillance, CPSP's data collection tools were enhanced to collect demographic, epidemiological, microbiological and clinical data including comorbidities of cases identified.</p><p><strong>Outcomes: </strong>Less than a month after the World Health Organization declared the COVID-19 pandemic, CPSP was able to start collecting detailed weekly case data on emerging cases of COVID-19 among Canadian children and youth. By May 2020, CPSP was able to launch a detailed study, supporting research into potential risk factors for severe COVID-19-related illness in children and youth.</p><p><strong>Conclusion: </strong>In response to a novel public health threat, CNPHI and CPSP were able to implement rapid adaptations and enhancements to existing data collection instruments while fortifying their preparedness to do the same in the future, when needed. With innovative and agile technologies at the ready, this experience helps to emphasize the importance of established collaborative partnerships across public health disciplines as a factor contributing to preparedness and agility to respond to the unforeseen. Canadian Network for Public Health Intelligence's Web Data technology showed agile adaptability and a capacity for complex and detailed data collection, supporting timely surveillance and response.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"9 1","pages":"190-196"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10896618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81551472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnic Diversity with Preventable Risk Factors for Cardiovascular Diseases","authors":"S. Kapoor, R. Tyagi, Meenal Dhall, P. Bhasin, N. K. Mungreiphy, K. Saluja, A. Kapoor","doi":"10.1080/09751270.2017.1354875","DOIUrl":"https://doi.org/10.1080/09751270.2017.1354875","url":null,"abstract":"ABSTRACT The objective of present paper is to investigate the extent of association of selected anthropometric markers with cardiovascular health risk among different environmental and culturally diverse population groups. A cross-sectional survey among 1,843 respondents (including 984 females and 859 males) was carried out covering population groups from five geographic zones of India. Data was collected for anthropometric and physiological variables using standardized techniques. Body mass index (BMI), waist to hip ratio (WHR) and waist to height ratio (WHtR) were computed. Odds ratios were obtained using multiple logistic regressions. Anthropometric markers, WHR, WHtR and WC showed highest association with cardiovascular (CV) health risk. The waist height ratio (WHtR) is found to be a better predictor of cardiovascular health risk amongst all the central adiposity indices. A model anthropometric score scale incorporating BMI and selected central adiposity indices may be a quick and meaningful screening tool for cardiovascular health risk assessment and its timely management.","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"9 1","pages":"1 - 10"},"PeriodicalIF":0.0,"publicationDate":"2017-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/09751270.2017.1354875","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59530623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D Dependent Rickets Type II with Alopecia","authors":"M. Murali, T. Usharani","doi":"10.1080/09751270.2013.11885216","DOIUrl":"https://doi.org/10.1080/09751270.2013.11885216","url":null,"abstract":"Abstract Vitamin D dependent rickets Type II (VDDR II) is a rare form of autosomal recessive disorder, which is inherited and often caused by mutation of a gene on vitamin D receptor which in turn prevents normal physiological response to 1, 25(OH)2 vitamin D. The elevated circulating levels of 1,25-dihydroxyvitamin D3 is a diagnostic feature of VDDR II, while the presence of alopecia differentiates it from vitamin D-dependent rickets Type I. VDDR II is considered to be the best example of aberrant target tissue response. The researchers thereby report a case of a two-year old female child with short stature, typical features of rickets and lack of hair growth. Upon investigation the level of 1,25(OH)2D was found to be high which is diagnostic of VDDR type II. The child was started on high dose of calcitriol and oral calcium but on follow-up did not show much improvement probably due to poor compliance.","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"5 1","pages":"57 - 59"},"PeriodicalIF":0.0,"publicationDate":"2013-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59530603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Supplementing Lactating Goats Rations with Garlic, Cinnamon or Ginger Oils on Milk Yield, Milk Composition and Milk Fatty Acids Profile","authors":"S.M. Kholif, T. Morsy, M. M. Abdo, O. H. Matloup, A.A. Abu El-Ella","doi":"10.1080/09751270.2012.11885191","DOIUrl":"https://doi.org/10.1080/09751270.2012.11885191","url":null,"abstract":"Abstract Plant essential oils are volatile aromatic compounds with antimicrobial activity that can alter ruminal fermentation when used as dietary supplements. Consequently, both milk quantity and quality can be modified. This work aims at verifying the effect of different plant essential oils (garlic, cinnamon and ginger oils) on the milk production when used as dietary additives. Twenty-eight lactating Damascus goats, seven days after parturition, were divided into four groups using complete randomized block design, with 90-days period to study the effect of adding Garlic oil (Alilum sativum) (GAR), Cinnamon oil (Cinnamomum cassia) (CIN) or Ginger oil (Zingiber officinale) (GIN) to their rations on milk yield and composition. These treatments included: (1) control ration consisted of concentrate feed mixture: bersem clover (40:60 dry matter bases); (2) control + 2 ml/head/day garlic oil; (3) control + 2 ml/head/day cinnamon oil; (4) control + 2 ml/head/day ginger oil. Ruminal volatile fatty acids and propionate proportions were increased and ruminal acetate proportion and ammonia nitrogen concentration were decreased with experimental additives. Blood serum proteins and glucose concentrations were increased and urea nitrogen and cholesterol concentrations were decreased with CIN and GAR additives. Results indicated that experimental additives, significantly increased (p<0.05) milk yield, protein and solids not fat contents compared with the control, however fat percent and milk non protein nitrogen were decreased (p<0.05) by treatments compared to the control. Total solids and ash were not affected by the experimental additives. The experimental additives were increased (p<0.05) unsaturated fatty acids in milk specially C18:1n9c and conjugated linoleic acids (CLA). CIN treatments increased C18:3N3 and C18:3N6 (omega 3 and omega6) compared with other treatments. In conclusion, plant essential oils especially CIN oil supplementation to ration of lactating goats had beneficial effects on milk yield and milk protein and so enhance healthy fatty acids (CLA and omega 3) contents in milk.","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"4 1","pages":"27 - 34"},"PeriodicalIF":0.0,"publicationDate":"2012-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/09751270.2012.11885191","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59530566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Genetic Markers with Mental Retardation","authors":"T.L. Pathi, M. Ramesh, S. Krishnasubha, V. Kalpana, G. Sudhakar","doi":"10.1080/09751270.2011.11885173","DOIUrl":"https://doi.org/10.1080/09751270.2011.11885173","url":null,"abstract":"Abstract Five red cell genetic markers namely, acid phosphatase locus 1 (ACP1), esterase D (ESD), glyoxalase locus 1 (GLO1), superoxide dismutase (SOD) and haemoglobin (HB) and five plasma proteins namely haptoglobin (HP), ceruloplasmin (CP), group specific component (GC), transferrin (TF) and albumin (ALB) were studied in mentally retarded individuals from Visakhapatnam area of north coastal Andhra Pradesh, South India. The results were compared with the data obtained from controls. Out of studied ten genetic markers, two namely ACP1 and HP showed significant differences between patients and controls. The risk estimates were also showing a significant association.","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"3 1","pages":"87 - 91"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59530560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of furosemide on the ionic composition of the arterial wall.","authors":"M F Villamil,&nbsp;J Ponce,&nbsp;C Amorena,&nbsp;A Müller","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Furosemide decreased the intracellular H2O, Cl and K content and Cl concentration of dog carotid arteries incubated in normal or high K Krebs (123 mM). Cl loss exceeded K loss in normal Krebs but was of the same magnitude in high K Krebs. The findings are compatible with the inhibition of a neutral K-Cl coupled uptake.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"9 1-2","pages":"9-14"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11749867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biphasic effects of ethanol on behavioral and electrophysiological parameters can be explained by functional organization of neural networks.","authors":"R Hari","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The biphasic effect of ethanol on the CNS is usually explained by assuming that excitatory and depressant effects are mediated by different mechanisms. The present alternative explanation states that ethanol depresses the activity of all neurons to the same extent, but that the biphasic effect can result from the functional organization of the neural network concerned. Current experimental evidence is in accordance with both explanations.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"9 1-2","pages":"15-17"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11447361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oscillatory potentials in the electroretinogram.","authors":"J Levett,&nbsp;J D McAvinn","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This paper presents an analog circuit model of the electroretinogram b-wave and subsequent oscillations postulated to result from the depolarization of the retinal glial cells produced by potassium. The system is described by a second-order equation which oscillates under conditions of light adaptation. With dark adaptation the oscillations undergo attenuation. Light falling on the retina ultimately liberates potassium ions and this ionic current is considered to be the system input. A first approximation is an exponentially decaying current which varies depending upon light background, flash intensity and various drug manipulations. This model is a reasonable fit to the electroretinogram over considerable light background levels and is suggested as a useful tool in the study of various pharmacological effects on retinal electrophysiology.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"9 1-2","pages":"19-27"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11447362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Possible microwave mechanisms of the mammalian nervous system.","authors":"P L Stocklin,&nbsp;B F Stocklin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The hypothesis is examined that the living mammal generates and uses electromagnetic waves in the lower microwave frequency region as an integral part of the functioning of central and peripheral nervous systems. Analysis of the potential energy of a protein integral to the neural membrane compared to that of an extracellular positive ion yields major known features of action potential generation, and identification of the integral protein as a microwave emitter and absorber by changes in rotational energy state. Prolate spheroidal analysis of the adult human brain/skull cavity shows capability to support modes in the range 200 MHz to 3 GHz; spatial mode properties correspond to gross anatomy and neuromorphology of the brain. Phase-lock loop interaction between lower microwave modes and action potential conduction results in pulse microwave/action potential generation observable by EEG instrumentation as brain waves; alpha waves occur if the corpus callosum is the major neural tract involved. Spatially consistent Lorentz forces of standing microwaves provide physical basis for correspondence of spatial properties of microwave modes with brain anatomy, and for the formation of myelin sheath and the nodes of Ranvier on larger neurons.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"9 1-2","pages":"29-51"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11749866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A behavioral version of catecholamine involvement in new learning rewarded by brain stimulation.","authors":"N L Freedman,&nbsp;F McCoy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Numerous studies in the rat indicate that catecholamines (CA) mediate rewarding properties of self-administered electrical stimulation to the brain. One such property is the learning of new response-reinforcement relationships. In the present experiment, amphetamine which potentiates CA at the synapse produces stereotypical responding but does not interfere with the learning of new response-reinforcement relationships. Apomorphine, which mimics dopamine (DA) at DA receptors, also produces stereotypy and interferes with learning. The results suggest that DA released by stimulation mediates the stereotyped responding seen in intracranial self-stimulation (ICS) but norepinephrine mediates reward of newly learned responses.</p>","PeriodicalId":76575,"journal":{"name":"T.-I.-T. journal of life sciences","volume":"9 1-2","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11531055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}