Effect of some antithrombogenic drugs on the polyethylene-Krebs solution interface.

Abstract

The effects of some antithrombogenic drugs on the streaming potentials found in the interface polyethylene-Krebs solutions were studied. Drugs such as dypiramidol, heparin and apsirine were tested in different concentrations. The variation of streaming potentials with the pressure gradient (fluid velocity) were experimentally determined, surface charge densities and degrees of coverage calculated. Surface charge densities were in the order of 4 X 10(-10) C/cm2, with very low degrees of surface coverage.