L Bron, D Soldati, A Zouhair, M Ozsahin, E Brossard, P Monnier, P Pasche
{"title":"[Treatment of laryngeal cancer: cordectomy or crico-hyoido-epiglottopexy versus radiotherapy].","authors":"L Bron, D Soldati, A Zouhair, M Ozsahin, E Brossard, P Monnier, P Pasche","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Both radiotherapy and endoscopic or open functional surgery are recognised treatments for laryngeal cancer stage I and II. A comparison between two groups of patients treated with either modality may clarify the indications for both treatments.</p><p><strong>Methods: </strong>Over a period of 13 years two separate series of patients were treated for laryngeal cancer (stage I and II) by either surgery (n = 72) or radiotherapy (n = 81). We have analysed and compared the two groups.</p><p><strong>Results: </strong>Statistical analyses show a better local control among patients treated with surgery, when the anterior commissure was involved (p < 0.01) or with extension of the tumour (T2). However, long-term survivals were not significantly different in the two groups. As postradiation recurrence was diagnosed at an early stage, salvage (requiring total laryngectomy in many cases) was efficient but contributed to an appreciable difference in the long-term laryngeal preservation rate between the two groups (91% after radiotherapy and 99% after surgery).</p><p><strong>Conclusion: </strong>The treatment of laryngeal cancer must always compromise between oncological efficiency and functional preservation. With anterior commissure involvement (T1b) or more extensive disease (T2), surgery appears to be better. Therefore, preservation of perfect laryngeal function should be subordinate to oncological safety.</p>","PeriodicalId":76532,"journal":{"name":"Schweizerische medizinische Wochenschrift. Supplementum","volume":"116 ","pages":"18S-21S"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21629228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Liposarcoma in the area of the head-neck].","authors":"D Harder, N Schmuziger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Liposarcoma is the second most common soft tissue sarcoma occurring in adults, though it rarely involves the head and neck region. Fewer than 100 such cases have been described in the literature. We present two additional cases and a review of the literature. Prognosis is mainly determined by histologic grade. A high incidence of local recurrence is typical of all subtypes. Complete surgical excision is the most effective treatment. In the head and neck region the extent of the excision is limited by the proximity of neurovascular structures. The benefits of adjuvant radiotherapy in head and neck liposarcoma remain uncertain. Studies on liposarcoma at other sites indicate that addition of radiotherapy to surgery may result in longer local recurrence-free survival, though without improvement of overall survival.</p>","PeriodicalId":76532,"journal":{"name":"Schweizerische medizinische Wochenschrift. Supplementum","volume":"116 ","pages":"70S-73S"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21628602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Correlation between objective criteria and subjective evaluation of symptoms in chronic rhinosinusitis].","authors":"R Giger, A M Kurt, J S Lacroix","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>We evaluated the possible correlations between the extent of inflammatory infiltration of the nasal mucosa caused by mechanical irritation (septal deviation and hypertrophy of the middle turbinate) and nasal airway resistance measured by rhinomanometry and acoustic rhinometry. Subjective evaluation of the nasal obstruction, rhinorrhoea and headache was done by visual analogic scale and compared with the inflammation.</p><p><strong>Patients and methods: </strong>40 patients with a more than 18 months' history of chronic rhinosinusitis associated with septal deviation and/or hypertrophy of the middle turbinate were included in the study. The density of inflammatory cells (graded from + to +3, where + means few and +3 abundant inflammatory cells) in the mucosa of the middle turbinate was evaluated histopathologically.</p><p><strong>Results: </strong>We found a significant correlation between subjective intensity of nasal obstruction and inflammation (mainly lymphocytes) of the middle turbinate mucosa and the value of nasal airway resistance measured by rhinomanometry. No correlation was found between the other parameters studied.</p><p><strong>Conclusion: </strong>Mechanical stimulation at the level of turbinoseptal contact causes inflammation in the mucosa which correlates with both subjective nasal airway resistance and rhinomanometry values.</p>","PeriodicalId":76532,"journal":{"name":"Schweizerische medizinische Wochenschrift. Supplementum","volume":"116 ","pages":"104S-107S"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21629026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Predictive value of nocturnal pulse oximetry in sleep apnea screening].","authors":"R Nuber, J Vavrina, W Karrer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The monitoring of overnight oxygen saturation is widely used for sleep apnoea screening. The point of this screening has been questioned as a wide range of sensitivity has been reported in the literature. In a prospective study 70 subjects presenting with a possible sleep apnoea-hypopnoea syndrome had overnight oximetry followed by polysomnography 2 to 4 months later. Compared to polysomnography, the sensitivity of oximetry for sleep apnoea-hypopnoea was 85.2%, the specificity 77.8% and the predictive value positive 96.3%. When short, non-significant, repetitive desaturations have been declared pathologic, sensitivity increased to 91.8%. In the hands of an expert user, oximetry represents an excellent instrument for detecting patients with sleep apnoea-hypopnoea. Patients with pathological nocturnal oximetry are candidates for nCPAP treatment and therefore should undergo a sleep laboratory investigation.</p>","PeriodicalId":76532,"journal":{"name":"Schweizerische medizinische Wochenschrift. Supplementum","volume":"116 ","pages":"120S-122S"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21629030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}