[慢性鼻窦炎症状客观标准与主观评价的相关性]。

R Giger, A M Kurt, J S Lacroix
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引用次数: 0

摘要

前言:我们评估了机械刺激(鼻中隔偏曲和中鼻甲肥大)引起的鼻黏膜炎症浸润程度与鼻道阻力之间可能的相关性,鼻道阻力是通过鼻测压法和声学鼻测压法测量的。采用视觉类比评分法主观评价鼻塞、流涕、头痛情况,并与炎症反应进行比较。患者和方法:研究纳入了40例慢性鼻窦炎病史超过18个月并伴有鼻中隔偏曲和/或中鼻甲肥大的患者。组织病理学评估中鼻甲黏膜炎症细胞密度(从+到+3分级,+表示炎症细胞少,+3表示炎症细胞丰富)。结果:我们发现主观鼻塞强度和中鼻甲黏膜炎症(主要是淋巴细胞)与鼻道阻力测量值有显著相关性。其他研究参数之间没有发现相关性。结论:鼻中隔接触水平的机械刺激引起粘膜炎症,这与主观鼻道阻力和鼻流测量值有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Correlation between objective criteria and subjective evaluation of symptoms in chronic rhinosinusitis].

Introduction: We evaluated the possible correlations between the extent of inflammatory infiltration of the nasal mucosa caused by mechanical irritation (septal deviation and hypertrophy of the middle turbinate) and nasal airway resistance measured by rhinomanometry and acoustic rhinometry. Subjective evaluation of the nasal obstruction, rhinorrhoea and headache was done by visual analogic scale and compared with the inflammation.

Patients and methods: 40 patients with a more than 18 months' history of chronic rhinosinusitis associated with septal deviation and/or hypertrophy of the middle turbinate were included in the study. The density of inflammatory cells (graded from + to +3, where + means few and +3 abundant inflammatory cells) in the mucosa of the middle turbinate was evaluated histopathologically.

Results: We found a significant correlation between subjective intensity of nasal obstruction and inflammation (mainly lymphocytes) of the middle turbinate mucosa and the value of nasal airway resistance measured by rhinomanometry. No correlation was found between the other parameters studied.

Conclusion: Mechanical stimulation at the level of turbinoseptal contact causes inflammation in the mucosa which correlates with both subjective nasal airway resistance and rhinomanometry values.

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