[喉癌的治疗:声带切除或环舌骨会厌固定术与放射治疗]。

L Bron, D Soldati, A Zouhair, M Ozsahin, E Brossard, P Monnier, P Pasche
{"title":"[喉癌的治疗:声带切除或环舌骨会厌固定术与放射治疗]。","authors":"L Bron,&nbsp;D Soldati,&nbsp;A Zouhair,&nbsp;M Ozsahin,&nbsp;E Brossard,&nbsp;P Monnier,&nbsp;P Pasche","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Both radiotherapy and endoscopic or open functional surgery are recognised treatments for laryngeal cancer stage I and II. A comparison between two groups of patients treated with either modality may clarify the indications for both treatments.</p><p><strong>Methods: </strong>Over a period of 13 years two separate series of patients were treated for laryngeal cancer (stage I and II) by either surgery (n = 72) or radiotherapy (n = 81). We have analysed and compared the two groups.</p><p><strong>Results: </strong>Statistical analyses show a better local control among patients treated with surgery, when the anterior commissure was involved (p < 0.01) or with extension of the tumour (T2). However, long-term survivals were not significantly different in the two groups. As postradiation recurrence was diagnosed at an early stage, salvage (requiring total laryngectomy in many cases) was efficient but contributed to an appreciable difference in the long-term laryngeal preservation rate between the two groups (91% after radiotherapy and 99% after surgery).</p><p><strong>Conclusion: </strong>The treatment of laryngeal cancer must always compromise between oncological efficiency and functional preservation. With anterior commissure involvement (T1b) or more extensive disease (T2), surgery appears to be better. Therefore, preservation of perfect laryngeal function should be subordinate to oncological safety.</p>","PeriodicalId":76532,"journal":{"name":"Schweizerische medizinische Wochenschrift. Supplementum","volume":"116 ","pages":"18S-21S"},"PeriodicalIF":0.0000,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Treatment of laryngeal cancer: cordectomy or crico-hyoido-epiglottopexy versus radiotherapy].\",\"authors\":\"L Bron,&nbsp;D Soldati,&nbsp;A Zouhair,&nbsp;M Ozsahin,&nbsp;E Brossard,&nbsp;P Monnier,&nbsp;P Pasche\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Both radiotherapy and endoscopic or open functional surgery are recognised treatments for laryngeal cancer stage I and II. A comparison between two groups of patients treated with either modality may clarify the indications for both treatments.</p><p><strong>Methods: </strong>Over a period of 13 years two separate series of patients were treated for laryngeal cancer (stage I and II) by either surgery (n = 72) or radiotherapy (n = 81). We have analysed and compared the two groups.</p><p><strong>Results: </strong>Statistical analyses show a better local control among patients treated with surgery, when the anterior commissure was involved (p < 0.01) or with extension of the tumour (T2). However, long-term survivals were not significantly different in the two groups. As postradiation recurrence was diagnosed at an early stage, salvage (requiring total laryngectomy in many cases) was efficient but contributed to an appreciable difference in the long-term laryngeal preservation rate between the two groups (91% after radiotherapy and 99% after surgery).</p><p><strong>Conclusion: </strong>The treatment of laryngeal cancer must always compromise between oncological efficiency and functional preservation. With anterior commissure involvement (T1b) or more extensive disease (T2), surgery appears to be better. Therefore, preservation of perfect laryngeal function should be subordinate to oncological safety.</p>\",\"PeriodicalId\":76532,\"journal\":{\"name\":\"Schweizerische medizinische Wochenschrift. Supplementum\",\"volume\":\"116 \",\"pages\":\"18S-21S\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2000-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Schweizerische medizinische Wochenschrift. Supplementum\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Schweizerische medizinische Wochenschrift. Supplementum","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

放疗和内镜或开放式功能手术是喉癌I期和II期公认的治疗方法。对两组患者进行比较,可以明确两种治疗的适应症。方法:在13年的时间里,两组独立的喉癌患者(I期和II期)分别接受手术(72例)和放疗(81例)的治疗。我们对两组进行了分析和比较。结果:统计分析显示,当前连合受损伤(p < 0.01)或肿瘤扩大(T2)时,手术治疗的患者局部控制较好。但两组患者的长期生存率无显著差异。由于放疗后的复发在早期被诊断出来,挽救(在许多情况下需要全喉切除术)是有效的,但两组之间的长期喉保管率有明显差异(放疗后91%,手术后99%)。结论:喉癌的治疗必须兼顾肿瘤疗效和功能保留。对于累及前联合关节(T1b)或更广泛的疾病(T2),手术似乎更好。因此,保持喉功能的完善应优先于肿瘤安全。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Treatment of laryngeal cancer: cordectomy or crico-hyoido-epiglottopexy versus radiotherapy].

Introduction: Both radiotherapy and endoscopic or open functional surgery are recognised treatments for laryngeal cancer stage I and II. A comparison between two groups of patients treated with either modality may clarify the indications for both treatments.

Methods: Over a period of 13 years two separate series of patients were treated for laryngeal cancer (stage I and II) by either surgery (n = 72) or radiotherapy (n = 81). We have analysed and compared the two groups.

Results: Statistical analyses show a better local control among patients treated with surgery, when the anterior commissure was involved (p < 0.01) or with extension of the tumour (T2). However, long-term survivals were not significantly different in the two groups. As postradiation recurrence was diagnosed at an early stage, salvage (requiring total laryngectomy in many cases) was efficient but contributed to an appreciable difference in the long-term laryngeal preservation rate between the two groups (91% after radiotherapy and 99% after surgery).

Conclusion: The treatment of laryngeal cancer must always compromise between oncological efficiency and functional preservation. With anterior commissure involvement (T1b) or more extensive disease (T2), surgery appears to be better. Therefore, preservation of perfect laryngeal function should be subordinate to oncological safety.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信