{"title":"Non-HLA immunological factors in eighteen HLA-identical renal allografts.","authors":"J B Dossetor, T Kovithavongs","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"438-44"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17287594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K J Kuiper, P E de Jong, D de Zeeuw, K H Schuur, G K van der Hem
{"title":"Restenosis of the renal artery after percutaneous transluminal renal angioplasty: an inevitable outcome?","authors":"K J Kuiper, P E de Jong, D de Zeeuw, K H Schuur, G K van der Hem","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We performed follow-up studies in 26 patients four to 36 months after percutaneous transluminal renal angioplasty. Restenosis was found in 47 per cent of the patients who had an atherosclerotic type of stenosis and in 14 per cent of the patients with fibromuscular dysplasia. We could not detect any significant differences between the atherosclerotic patients who did develop restenosis and those who did not. In fact, the presence of generalised atherosclerosis, the severity of the stenosis and the initial success of the dilatation were similar in the two groups. It thus cannot be predicted which patients will develop restenosis.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"538-45"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17292001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Brynger, L Rydberg, B Samuelsson, I Blohmé, A Lindholm, L Sandberg
{"title":"Renal transplantation across a blood group barrier--'A2' kidneys to 'O' recipients.","authors":"H Brynger, L Rydberg, B Samuelsson, I Blohmé, A Lindholm, L Sandberg","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The outcome of 11 renal transplants with kidneys from blood group A2 donors to blood group O recipients is reported. Eight grafts had a satisfactory function, three early losses were noted: one acute rejection after four weeks, two technical failures. The longest survival is four years, the patient died from septicaemia with a functioning graft. Obviously, the blood group A2-O incompatibility is not an obstacle to successful organ transplantation.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"427-31"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17408810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Milutinović, D Breyer, M Janković, A Stefović, V Molnar, V Mrzljak, B Rocić
{"title":"Improvement of insulin binding to erythrocyte insulin receptors in uraemia by haemodialysis.","authors":"S Milutinović, D Breyer, M Janković, A Stefović, V Molnar, V Mrzljak, B Rocić","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Insulin binding to erythrocytes obtained from uraemic patients was determined using a radioreceptor assay. The binding was reduced by 50 per cent in 20 non-diabetic uraemic patients in comparison with 20 controls (4.7 +/- 1.79 vs 9.37 +/- 1.30 (mean +/- SD) p less than 0.01). During the course of haemodialysis insulin binding steadily increased in a time dependent manner in proportion to the efficiency of haemodialysis as assessed by relative decrease in plasma urea, uric acid or creatinine. Incubation of healthy donors' erythrocytes with uraemic plasma resulted in a dose dependent inhibition of insulin binding with a maximum of 40 per cent. These data indicate the presence of dialysable inhibitors of insulin binding in uraemic plasma.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"763-8"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17409394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F Collart, C Tielemans, M Dratwa, L Schandene, J Wybran, E Dupont
{"title":"Haemodialysis, continuous ambulatory peritoneal dialysis and cellular immunity.","authors":"F Collart, C Tielemans, M Dratwa, L Schandene, J Wybran, E Dupont","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The cellular immunity of haemodialysis and continuous ambulatory peritoneal dialysis (CAPD) patients was studied with regards to T-lymphocyte subsets and to suppressor T-cell function. The two groups of patients showed similar alterations: low proportions of suppressor-cytotoxic T-cells and low suppressive activity. In both groups there is a deterioration of this suppressive activity with time on dialysis.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"190-4"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17293818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Outcome of renal grafts with multiple or damaged vessels.","authors":"A Vegeto, L Berardinelli, C Beretta, L L Militano","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We have examined a total of 708 donor kidneys for vascular abnormalities. Twenty-two point seven per cent of these had arterial damage or anomalies and in 11 per cent venous abnormalities were found. Five hundred and fifty-one of these kidneys were transplanted in our centre. Excluding 38 recipients of living related donor grafts there was a slightly higher incidence of re-operation and urological complications amongst the recipients of kidneys which had either required bench-top arterial microvascular surgery for vessels damaged at donor nephrectomy or which had multiple vessels. However, the function and actuarial graft survival of such kidneys differed little from those of kidneys transplanted with a conventional single arterial anastomosis.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"477-81"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17408632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of urine cytology versus fine needle aspiration cytology in monitoring renal allograft dysfunction.","authors":"B Spohn, H Bauer, E Gmähle, R Guth, H E Franz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In renal allograft monitoring we performed daily urine cytology (UC) (n = 773) and fine needle aspiration cytology (FNAC) (n = 144) two to three times weekly in 29 allograft recipients with 18 acute rejection episodes. UC is more accurate in diagnosis and therapeutic control of acute rejection episodes. In addition UC is better than FNAC in revealing non-rejection causes of graft dysfunction such as interstitial nephritis (pyelonephritis, allergic nephritis), the presence of bacteria, fungi and virus inclusion bearing cells in the sediment and nephrotoxic tubular damage.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"495-9"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17408634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G Barsotti, E Morelli, A Guiducci, A Giannoni, F Ciardella, F Niosi, S Lupetti, S Giovannetti
{"title":"Three years experience with a very low nitrogen diet supplemented with essential amino acids and keto-analogues in the treatment of chronic uraemia.","authors":"G Barsotti, E Morelli, A Guiducci, A Giannoni, F Ciardella, F Niosi, S Lupetti, S Giovannetti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A low nitrogen, low phosphorus diet, supplemented with essential amino acids and keto-analogues, was administered to 48 chronic uraemics for a maximum of 36 months. In 10 cases renal function deteriorated and dialysis was started; eight patients changed to the dialytic therapy having difficulties in complying to the diet and three died for reasons not directly related to renal failure. The remaining twenty-seven patients are still on dietetic treatment and their renal function has not changed significantly. Their serum inorganic phosphorus and their circulating iPTH decreased significantly. Their subjective and objective conditions are satisfactory and no manifestation of protein malnutrition or other unwanted effects are detectable.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"773-8"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17927673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improved kidney graft survival through HLA-DR-MT matching.","authors":"G A Müller, C Müller, P Wernet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The influence of prospective HLA-DR matching on cadaver kidney graft survival rate was investigated in 85 transplants performed during 1979 and 1980 within the South German Cooperative Study Group for Kidney Transplantation. Prospective HLA-DR matching showed a clear influence on graft outcome as all HLA-DR identical grafts were still functioning after a period of one year and reached a two year graft survival rate of 82 per cent compared to 60/43 per cent of the groups mismatched for one/two HLA-DR antigens. Seventy-four donors and recipients were simultaneously typed for their MT-specificities. In a retrospective analysis seventeen grafts matched for two MT-specificities had a two year graft survival rate of 94 per cent which was significantly better than that of grafts mismatched for one (53%) or both (17%) MT-specificities. According to these results MT matching of donors and recipients seems to have a superior influence on kidney graft outcome than donor-recipient selection due to HLA-DR identity.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"464-8"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17408813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of haemodialysis on insulin requirements in uraemic diabetic patients. Studies with the artificial beta-cell.","authors":"O Schmitz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study investigates the effect of dialysis on the 24-hour insulin requirements in uraemic insulin dependent diabetic patients maintained at normoglycaemia using an artificial beta-cell. Five patients were studied twice, namely before initiation of dialysis treatment (mean 14 days) and after a mean of 46 days on chronic dialysis. The mean total diurnal insulin consumption was reduced significantly from 44.7 +/- 2.9 U (mean +/- SEM) before dialysis to 35.0 +/- 2.3 U after dialysis therapy (p less than 0.01). The reduction included the prandial as well as the basal insulin requirements (p less than 0.02). It is most likely that an insulin receptor or a post-receptor defect account for the insulin insensitivity present in uraemia. Our study demonstrates that this defect is at least partly reversible after dialysis treatment.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"769-72"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17409395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}