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Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association最新文献

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Acute vascular rejection treated by plasma exchange. 血浆置换治疗急性血管排斥反应。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
W Fassbinder, W Ernst, H J Stutte, E Scheuermann, U Frei, W Schoeppe
{"title":"Acute vascular rejection treated by plasma exchange.","authors":"W Fassbinder,&nbsp;W Ernst,&nbsp;H J Stutte,&nbsp;E Scheuermann,&nbsp;U Frei,&nbsp;W Schoeppe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Since 1980 we have treated in 14 patients 19 steroid resistant acute vascular rejection (AVR) episodes by plasma filtration (PF). Each episode was treated by six PF with 5L plasma being filtered and simultaneously replaced by 3.5 per cent Albumin-Ringer-lactate. After each PF 20g immunoglobulin (Intraglobin) was given intravenously. In all cases renal function improved following PF. In the long term one graft was lost due to chronic irreversible vascular rejection, all others are still functioning, nine of them six months and eight of them 12 months post PF treatment. They show no signs of rejection. PF with repletion of immunoglobulins after treatment is a simple and safe procedure, which in our hands proved to be quite effective in reversal of AVR.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"536-43"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17408635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma prednisolone concentrations and kinetics in renal transplant patients. 肾移植患者血浆强的松龙浓度和动力学。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
W E Nelson, C C Doherty, J F Douglas, M G McGeown, H Delargy, D J Temple
{"title":"Plasma prednisolone concentrations and kinetics in renal transplant patients.","authors":"W E Nelson,&nbsp;C C Doherty,&nbsp;J F Douglas,&nbsp;M G McGeown,&nbsp;H Delargy,&nbsp;D J Temple","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Plasma prednisolone concentrations were measured in 26 renal transplant (RT) patients and five control subjects. A linear relationship was found between prednisolone dosage in mg/kg and area under the plasma concentration time curve in seven stable RT patients (r = 0.98) and in all subjects (n = 19) with estimated prednisolone clearance rates (CLp) between 0.075 and 0.11 L/kg/hr (r = 0.96). The greatest deviation from this occurred in five patients having reduced CLp with prolonged prednisolone half life (t1/2p) and in one having increased CLp while taking phenytoin. Three of the five with reduced clearance had steroid induced diabetes and one a Cushingoid appearance. There was some correlation between peak plasma prednisolone and dosage (r = 0.77) in all subjects, but none between creatinine clearance and t1/2p or CLp.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"544-51"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17408636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanisms of progression in glomerulonephritis. 肾小球肾炎的进展机制。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
J S Cameron
{"title":"Mechanisms of progression in glomerulonephritis.","authors":"J S Cameron","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"617-26"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17408639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of immunological parameters in kidney transplantation. 免疫参数在肾移植中的作用。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
J M Kreisler
{"title":"The role of immunological parameters in kidney transplantation.","authors":"J M Kreisler","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"407-23"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17408809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma exchange in severe glomerulonephritis--who benefits? 血浆置换治疗严重肾小球肾炎——谁受益?
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
C P Swainson, R J Winney, S J Urbaniak, J S Robson
{"title":"Plasma exchange in severe glomerulonephritis--who benefits?","authors":"C P Swainson,&nbsp;R J Winney,&nbsp;S J Urbaniak,&nbsp;J S Robson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Plasma exchange (PE) and immunosuppression was used in the treatment of 17 patients with severe glomerulonephritis and 17 acute rejections in transplant recipients. No response occurred in crescentic nephritis with anuria; a temporary improvement occurred in other nephritis patients but half of these relapsed on immunosuppression alone. Seven rejection episodes responded. Responses always occurred promptly and prolonged PE did not improve the results. Histology, serum complement or immune complex results did not predict a successful outcome.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"732-7"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17409393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glucose, insulin and C-peptide kinetics during continuous ambulatory peritoneal dialysis. 连续动态腹膜透析期间的葡萄糖、胰岛素和c肽动力学。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
T E Wideröe, L C Smeby, O L Myking, T Wessel-Aas
{"title":"Glucose, insulin and C-peptide kinetics during continuous ambulatory peritoneal dialysis.","authors":"T E Wideröe,&nbsp;L C Smeby,&nbsp;O L Myking,&nbsp;T Wessel-Aas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The insulin and C-peptide kinetics due to glucose (50 g), given intraperitoneally or enterally has been compared in five non-diabetic patients on continuous ambulatory peritoneal dialysis (CAPD). The fasting C-peptide concentrations were three to ten times the normal values whereas the fasting plasma insulin concentrations were within normal limits. After intraperitoneal glucose administration a more marked hyperglycaemia (p less than 0.05) and a more long lasting hyperinsulinaemia (p less than 0.05) was found than after the enteral glucose load. The relative change in plasma C-peptide was slower and less pronounced in both experiments. C-peptide concentration in plasma did not differ significantly between the two experiments. Estimated total body clearance (Kt) for insulin was higher than for C-peptide (p less than 0.01), but dialysis clearance (Kd) for C-peptide was higher than for insulin in both experiments (p less than 0.01).</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"195-200"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17421386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of blood transfusions on renal transplants: considering exclusive blood products and donor relationship. 输血对肾移植的影响:考虑独家血液制品和献血者关系。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
S T Perdue, P I Terasaki
{"title":"Effects of blood transfusions on renal transplants: considering exclusive blood products and donor relationship.","authors":"S T Perdue,&nbsp;P I Terasaki","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"253-62"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17421389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Different prednisolone pharmacokinetics in Cushingoid and non-Cushingoid kidney transplant patients. 强的松龙在库欣类和非库欣类肾移植患者中的药代动力学差异。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
H Bergrem, J Jervell, A Flatmark
{"title":"Different prednisolone pharmacokinetics in Cushingoid and non-Cushingoid kidney transplant patients.","authors":"H Bergrem,&nbsp;J Jervell,&nbsp;A Flatmark","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Prednisolone pharmacokinetics have been compared in 16 Cushingoid and 46 non-Cushingoid long term kidney transplant recipients. The Cushingoid patients had a significantly (p less than 0.05) higher peak concentration, a longer elimination half-time, a greater area under the time-concentration curve of total and free prednisolone, and a lower total body clearance of prednisolone. It is suggested that prednisolone pharmacodynamics may be influenced by pharmacokinetic differences, and that differences in renal function may be an important contributing factor.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"286-90"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17421392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new mechanism of humoral immunodepression in chronic renal failure and its importance to dialysis and transplantation. 慢性肾衰竭体液免疫抑制的新机制及其对透析和移植的重要性。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
P K Donnelly, B K Shenton, A M Alomran, D M Francis, G Proud, R M Taylor
{"title":"A new mechanism of humoral immunodepression in chronic renal failure and its importance to dialysis and transplantation.","authors":"P K Donnelly,&nbsp;B K Shenton,&nbsp;A M Alomran,&nbsp;D M Francis,&nbsp;G Proud,&nbsp;R M Taylor","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Whilst chronic renal failure (CRF) patients are known to have an impaired immune response the explanation is unclear. We investigated the immunosuppressive effect of plasma from CRF patients on an in vitro assay of normal lymphocyte function. One hundred and sixty regular dialysis patients had significantly greater plasma suppressive activity (PSA) than that of normal healthy subjects. PSA decreased after haemodialysis but increased after blood transfusion. Renal allograft recipients with low PSA were more likely to have accelerated rejection. Assay of the functional capacity of plasma for inhibiting protease (e.g. plasmin, thrombin, trypsin) suggest that high PSA is associated with the excess formation of protease-inhibitor complexes and liberation of immunoregulatory peptide (less than 10,000 daltons).</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"297-304"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17422213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Respiratory response of acetate dialysis and bicarbonate dialysis. 醋酸盐透析和碳酸氢盐透析的呼吸反应。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
A Salvadeo, G Pezzagno, S Segagni, F Galli, G Villa, F Poggio, V Piazza, G Bovio, L Picardi, E Petrella, L Bigi
{"title":"Respiratory response of acetate dialysis and bicarbonate dialysis.","authors":"A Salvadeo,&nbsp;G Pezzagno,&nbsp;S Segagni,&nbsp;F Galli,&nbsp;G Villa,&nbsp;F Poggio,&nbsp;V Piazza,&nbsp;G Bovio,&nbsp;L Picardi,&nbsp;E Petrella,&nbsp;L Bigi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"334-9"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17470335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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