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Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association最新文献

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B lymphocyte antibodies associated with successful renal transplantation and successful pregnancy. B淋巴细胞抗体与肾移植成功和妊娠成功相关。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
A M MacLeod, D A Power, R J Mason, K N Stewart, G Shewan, N Edward, G R Catto
{"title":"B lymphocyte antibodies associated with successful renal transplantation and successful pregnancy.","authors":"A M MacLeod,&nbsp;D A Power,&nbsp;R J Mason,&nbsp;K N Stewart,&nbsp;G Shewan,&nbsp;N Edward,&nbsp;G R Catto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study shows that non-cytotoxic Fc receptor blocking antibodies occurred more frequently in pre-transplant sera when the recipient had been transfused over five units of blood. Moreover 7/12 previously untransfused patients developed Fc receptor blocking antibodies during an elective blood transfusion regime. Erythrocyte antibody-rosette-inhibiting antibodies were also found at significantly higher values in the sera of women during the first trimester of a normal first pregnancy than in women studied at the time of spontaneous abortion. Family studies showed that this activity was linked to the HLA gene complex. These results indicate that EA inhibiting antibodies directed against MHC linked antigens are associated with specific abrogation of the immune response.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"460-3"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17470339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Continuous ambulatory peritoneal dialysis and cellular immunity. 连续流动腹膜透析与细胞免疫。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
A Giangrande, P Cantù, A Limido, D de Francesco, V Malacrida
{"title":"Continuous ambulatory peritoneal dialysis and cellular immunity.","authors":"A Giangrande,&nbsp;P Cantù,&nbsp;A Limido,&nbsp;D de Francesco,&nbsp;V Malacrida","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>E+-cells were studied in 16 patients on continuous ambulatory peritoneal dialysis (CAPD) to evaluate the impairment of cell-mediated immunity. E-rosette forming cells (E-RFC) were below the normal range at the beginning of treatment in 10/16 patients, after which their number increased and reached normal levels in the majority of patients in three to six months. In this phase of therapy, the same result was obtained with OKT11 monoclonal antibody, while OKT+4/OKT+8 ratio was in the normal range. Normal human lymphocytes, pre-incubated with uraemic peritoneal fluid, showed a significant reduction of E-RFC. Maximum inhibition was observed with the less than 500 daltons fraction of peritoneal fluid. Extraction with chloroform almost completely abolished inhibitory activity, suggesting that the toxic substance(s) has the characteristic of a polar lipid. Immunodeficiency in CAPD patients seems therefore partly restored by the removal through the peritoneum of inhibitors capable of blocking sheep-cell receptors.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"372-9"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17659225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cortical infarction in rabbits with serum sickness following Cyclosporin A therapy. 环孢素A治疗兔血清病并发皮质梗死的研究。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
G H Neild, K Ivory, D G Williams
{"title":"Cortical infarction in rabbits with serum sickness following Cyclosporin A therapy.","authors":"G H Neild,&nbsp;K Ivory,&nbsp;D G Williams","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Rabbits given acute serum sickness (ASS) and treated with Cyclosporin A (CyA) developed glomerular capillary thrombosis and cortical infarction. These lesions were associated with severe endothelial injury and platelet-fibrin-leucocyte thrombi. They were not seen in untreated rabbits with ASS, nor in normal rabbits given CyA alone in equivalent doses. A similar renal lesion has been reported in patients receiving CyA following bone marrow transplantation.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"662-8"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17712215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of renal lithiasis associated with renal tubular acidosis. 肾小管酸中毒合并肾结石的治疗。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
C J Van den Berg, T M Harrington, T W Bunch, A M Pierides
{"title":"Treatment of renal lithiasis associated with renal tubular acidosis.","authors":"C J Van den Berg,&nbsp;T M Harrington,&nbsp;T W Bunch,&nbsp;A M Pierides","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In order to determine the incidence of renal lithiasis in patients with renal tubular acidosis and the effect of therapy on further stone formation, we reviewed the clinical and laboratory manifestations, X-ray findings, and treatment of 48 patients with renal tubular acidosis who were seen at the Mayo Clinic during the years 1970-1980. Thirty-four patients (70%) had radiological evidence of renal lithiasis which was the presenting symptom in 23 (48%) patients. In every instance the calculi were multiple and, with one exception, bilateral. While receiving therapy, 19 patients with renal lithiasis were followed for longer than one year with sequential uroradiographic studies. Fifteen of these patients were treated with oral base alone and thirteen had no evidence of new stone formation or continued growth of existing stones during therapy. The two patients with X-ray evidence of continued stone formation admitted to poor compliance. Four patients received initial treatment with an oral phosphorus supplement. Three of these four patients had radiographic evidence of continued renal stone formation during three, five and eight years of phosphate therapy. We conclude renal lithiasis is a frequent complication of renal tubular acidosis, and adequate base replacement is effective therapy to stop continued stone formation while oral phosphate therapy alone is often ineffective.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"473-6"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17712315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dopaminergic control of sympathetic activity and blood pressure in haemodialysis patients. 血液透析患者交感神经活动和血压的多巴胺能控制。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
A Sturani, E Degli Esposti, A De March, A Santoro, G Fuschini, A Zuccalà, C Chiarini, C Flamigni, P Zucchelli
{"title":"Dopaminergic control of sympathetic activity and blood pressure in haemodialysis patients.","authors":"A Sturani,&nbsp;E Degli Esposti,&nbsp;A De March,&nbsp;A Santoro,&nbsp;G Fuschini,&nbsp;A Zuccalà,&nbsp;C Chiarini,&nbsp;C Flamigni,&nbsp;P Zucchelli","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bromocriptine was used to test the hypothesis that the abnormality of the dopaminergic system described in haemodialysis patients may cause enhanced sympathetic activity and high blood pressure. Bromocriptine significantly reduced supine mean blood pressure and plasma noradrenaline. Moreover, although the increments in plasma noradrenaline during tilt tests were reduced by bromocriptine there was a significant improvement in the response of blood pressure. These results suggest that dopaminergic control of sympathetic activity may be impaired in haemodialysis patients and may be a cause of high blood pressure. Moreover, a restoration of a normal relationship between noradrenaline and adrenergic receptors would be consistent with the present results.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"156-60"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17712727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pyridoxine therapy in patients with renal calcium oxalate calculi. 吡哆醇治疗肾性草酸钙结石。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
P Balcke, P Schmidt, J Zazgornik, H Kopsa, E Minar
{"title":"Pyridoxine therapy in patients with renal calcium oxalate calculi.","authors":"P Balcke,&nbsp;P Schmidt,&nbsp;J Zazgornik,&nbsp;H Kopsa,&nbsp;E Minar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 12 patients with idiopathic calcium oxalate calculi pyridoxine was administered. Within six weeks mean daily oxalic acid excretion decreased from 480 +/- 122 mumol to 336 +/- 83 mumol. Glycolic acid excretion fell from 208 +/- 51 mumol to 153 +/- 26 mumol (normal range: oxalic acid 228-412 mumol/day, glycolic acid 130-290 mumol/day). The reduction of oxalic acid excretion seems to be beneficial in prevention of idiopathic calcium oxalate calculi.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"417-21"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17713593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Renal threshold phosphate concentration in patients with idiopathic nephrolithiasis: correlations with tubular functions, serum parathyroid hormone and 1,25(OH)2D3. 特发性肾结石患者肾阈值磷酸盐浓度:与肾小管功能、血清甲状旁腺激素和1,25(OH)2D3的相关性
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
R C Pabico, B A McKenna, R B Freeman
{"title":"Renal threshold phosphate concentration in patients with idiopathic nephrolithiasis: correlations with tubular functions, serum parathyroid hormone and 1,25(OH)2D3.","authors":"R C Pabico,&nbsp;B A McKenna,&nbsp;R B Freeman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The renal handling of inorganic phosphate was measured in 17 idiopathic nephrolithiasis patients with normal glomerular filtration rate and effective renal plasma flow. TmPO4/GFR was less than 2.5 mg/dl in nine subjects (Group I) and greater than or equal to 2.5 in eight (Group II). The former had serum PO4 of 2.5 +/- 0.13 mg/dl and the latter, 3.5 +/- 0.11 mg/dl (p less than 0.01). Four in Group I and five in Group II were hypercalciuric. There was no significant difference in the serum parathyroid hormone and 1,25(OH)2D3 between the two groups. However, renal tubular functions were abnormal in both groups. The low TmPO4/GFR in 53 per cent of the patients is another manifestation of tubular functional abnormality seen in idiopathic nephrolithiasis.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"450-4"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17744940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphologic and functional tubular changes in chronic glomerulonephritis. 慢性肾小球肾炎肾小管形态及功能改变。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
H Klinkmann, M Ratner, V V Serov, H Nizze, B I Rosenfeld, W Sinn, R Schmicker
{"title":"Morphologic and functional tubular changes in chronic glomerulonephritis.","authors":"H Klinkmann,&nbsp;M Ratner,&nbsp;V V Serov,&nbsp;H Nizze,&nbsp;B I Rosenfeld,&nbsp;W Sinn,&nbsp;R Schmicker","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 135 patients with different glomerular diseases but normal glomerular filtration rates (CCr and In = 103 +/- 2ml/min) correlations between morphological tubular lesions (tic) and changes in tubular function were investigated. Between the extent of tubular lesions and the impairment of specific tubular functions (formula; see text) exists a highly significant correlation. The combined diminution in Uosmmax and UNH4 + V reflects in 72 per cent the appearance of a severe tubular lesion and should be used for its clinical recognition.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"679-85"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17927670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
pH--dependence of phosphate absorption in rat renal proximal tubule. 大鼠肾近端小管磷酸吸收的pH依赖性。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
I Samarzija, V Molnar, E Frömter
{"title":"pH--dependence of phosphate absorption in rat renal proximal tubule.","authors":"I Samarzija,&nbsp;V Molnar,&nbsp;E Frömter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Proximal tubular cell membrane potentials were measured in rat kidney in vivo and the response to luminal perfusion of 2mmolar phosphate (Pi) was studied. Pi transport was preferentially rheogenic at low pH (cotransport of 1H2PO2- plus 2Na+) but preferentially electroneutral at high pH (cotransport of 1HPO4--plus 2Na+). The potential response as a function of pH conformed to a model which transports both H2PO4- and HPO4--indiscriminately and whose maximal transport capacity increases with increasing pH. Further kinetic experiments are required to definitely exclude separate transport systems for both ionised forms. Hypercapnic phosphaturia may be explained by a decreased maximal transport capacity of Pi at low luminal pH.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"779-83"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17927674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endocrine-metabolic effects of l-carnitine in patients on regular dialysis treatment. 左旋肉碱对透析治疗患者内分泌代谢的影响。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
A Albertazzi, P Capelli, B Di Paolo, P Pola, P Tondi, O Vaccario
{"title":"Endocrine-metabolic effects of l-carnitine in patients on regular dialysis treatment.","authors":"A Albertazzi,&nbsp;P Capelli,&nbsp;B Di Paolo,&nbsp;P Pola,&nbsp;P Tondi,&nbsp;O Vaccario","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Twenty-three patients on regular dialysis treatment (RDT) were given 1-carnitine orally or in dialysate for six months. All patients remained in a stable biochemical state; hyperlipidaemia was reduced with an increase in HDL-cholesterol. Hormonal pattern was unmodified. Serum and muscle carnitine and acetylcarnitine constantly increased. L-carnitine in RDT, by restoring tissue reserves, improves metabolic alterations without any side-effects.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"302-7"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17928993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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