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Participation of renal prostaglandins in the nephrotic syndrome. 肾前列腺素在肾病综合征中的作用。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
L Ruilope, V G Millet, J M Alcazar, C Prieto, J A Tresguerres, R Garcia-Robles, J Sancho, J L Rodicio
{"title":"Participation of renal prostaglandins in the nephrotic syndrome.","authors":"L Ruilope,&nbsp;V G Millet,&nbsp;J M Alcazar,&nbsp;C Prieto,&nbsp;J A Tresguerres,&nbsp;R Garcia-Robles,&nbsp;J Sancho,&nbsp;J L Rodicio","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The participation of renal prostaglandins in the nephrotic syndrome has been investigated by the measurement of the urinary excretion of prostaglandin E2 (PGE2), renal function and the renin-angiotensin-aldosterone system before, during and after the administration of indomethacin in a group of patients diagnosed as having chronic idiopathic glomerulonephritis with and without nephrotic syndrome. Our results indicate increased renal production of PGE2 in nephrotic patients. This contributes to the maintenance of renal function, probably by counteracting an activated renin-angiotensin system and could be accompanied by a simultaneous and deleterious enhancement of the degree of proteinuria. Nevertheless, the participation of angiotensin II in this last even cannot be excluded.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"738-43"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17632911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acetohydroxamate in struvite stones: in vivo study. 鸟粪石结石中的乙酰羟酸酯:体内研究。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
A Aroldi, G Graziani, C Castelnovo, G Colussi, M Surian, A Mandressi, E Mascheroni, I Pazardjiklian, A Pagano, C Ponticelli
{"title":"Acetohydroxamate in struvite stones: in vivo study.","authors":"A Aroldi,&nbsp;G Graziani,&nbsp;C Castelnovo,&nbsp;G Colussi,&nbsp;M Surian,&nbsp;A Mandressi,&nbsp;E Mascheroni,&nbsp;I Pazardjiklian,&nbsp;A Pagano,&nbsp;C Ponticelli","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This report describes the results obtained with a combination of acetohydroxamic acid (AHA) and antibacterial agents in 13 patients with recurrent struvite stones complicated by refractory infections with urease-producing bacteria. Intravenous antibiotic pulses plus oral AHA achieved urine sterilisation in all. Then oral chemotherapy plus AHA was given for a mean period of 10.8 +/- 5.4 months. In four patients, the urine remained sterile, but in all the patients urinary pH remained below 6.4 and urinary NH4+ below 40 mg/dl. Despite the persistence of urea-splitting bacteria, the radiographic data showed an arrest of stone growth during the first year of treatment.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"469-72"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17712314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term continuous ambulatory peritoneal dialysis. 长期连续非卧床腹膜透析。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
C T Flynn
{"title":"Long-term continuous ambulatory peritoneal dialysis.","authors":"C T Flynn","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This paper reports experience with 65 patients treated by continuous ambulatory peritoneal dialysis (CAPD) during the past five years. The patients are divided into 33 non-diabetic and 32 diabetic and the latter are subdivided into blind and sighted. Cumulative actuarial survival on CAPD calculated at five years was highest for blind diabetics, intermediate for non-diabetic and lowest for sighted diabetics. Blind diabetics had the lowest rate of drop-out from CAPD. Many patients, especially in the non-diabetic and sighted diabetic groups required temporary haemodialysis which allowed them to return to CAPD.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"700-4"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17713127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed clearance of specific polymeric IgA immune complexes in patients with IgA nephropathy. IgA肾病患者特异性聚合IgA免疫复合物的延迟清除。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
J Sancho, J Egido, F Rivera, L Hernando
{"title":"Delayed clearance of specific polymeric IgA immune complexes in patients with IgA nephropathy.","authors":"J Sancho,&nbsp;J Egido,&nbsp;F Rivera,&nbsp;L Hernando","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The presence of multimeric (polymeric and monomeric) IgA immune complexes (IC), detected by Raji cell assay and by the inhibition binding assay, as well as the specific polymeric IgA-IC were examined before and after the ingestion of 100 g protein. A rise in multimeric IgA-IC occurred in three out of seven controls with a peak at two to four hours after the meal, being cleared thereafter. The amount of multimeric IC present at fasting in four of six patients diminished at two to four hours after food challenge reaching a new peak around six hours. In both controls and patients, IC containing antibodies against diet antigens (e.g. ovalbumin) paralleled those of multimeric IgA-IC. In controls the specific polymeric IgA-IC presented a maximal peak with distribution similar to multimeric IgA-IC, but with a faster disappearance from the circulation. By contrast, polymeric IgA-IC remained elevated 24 hours after food ingestion in most patients. These results suggest that a defect in the hepatic clearance of circulating polymeric IgA-IC exists in patients with IgA nephropathy.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"617-22"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17712210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of infected stone disease with hydroxyurea: a five year follow-up. 羟基脲治疗感染性结石:5年随访
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
M J Smith
{"title":"Management of infected stone disease with hydroxyurea: a five year follow-up.","authors":"M J Smith","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hydroxyurea in a morning dose of 500 mg along with Macrodantin, 100 mg, has been used for more than five years as an adjunct to the management of retained struvite stones. Mild reversible toxicity occurs in 10 per cent. Urine sterility can be achieved in ninety per cent and no growth of the retained stone occurs.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"466-8"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17712313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Specific angiotensin binding to human blood cells. 与人体血细胞结合的特定血管紧张素。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
J F Mann, J M Sis, E Ritz
{"title":"Specific angiotensin binding to human blood cells.","authors":"J F Mann,&nbsp;J M Sis,&nbsp;E Ritz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"562-5"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17712319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of diffusion and ultrafiltration on cardiac output and organ blood flows. 扩散和超滤对心输出量和器官血流量的影响。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
T Kishimoto, K Sugimura, T Nakatani, S Yamagami, K Ezaki, S Okazaki, M Maekawa
{"title":"The effects of diffusion and ultrafiltration on cardiac output and organ blood flows.","authors":"T Kishimoto,&nbsp;K Sugimura,&nbsp;T Nakatani,&nbsp;S Yamagami,&nbsp;K Ezaki,&nbsp;S Okazaki,&nbsp;M Maekawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of diffusion and ultrafiltration on cardiac output (CO) and organ blood flow (BF) in the uraemic dog were studied by a modified microsphere technique. In the diffusion phase of sequential therapy, a decrease in mean arterial pressure (MAP) and total peripheral resistance (TPR) was noted despite no change in circulatory plasma volume (CPV) and CO. In the ultrafiltration (UF) phase, MAP recovered with an increase in TPR despite the decrease in CPV and CO. Muscle vascular resistance increased in UF phase but not in the diffusion phase. The results suggest that the decrease in CPV through UF resulted in CO decrease, but that the compensation mechanism for the decrease is impaired by diffusion.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"275-80"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17928989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parathyroid ultrasonography and fine-needle aspiration biopsy in the diagnosis of secondary hyperparathyroidism. 甲状旁腺超声及细针穿刺活检诊断继发性甲状旁腺功能亢进。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
L Solbiati, A Giangrande, G Montali, C Ravetto, C Bazzi, G Sorgato, T Ierace
{"title":"Parathyroid ultrasonography and fine-needle aspiration biopsy in the diagnosis of secondary hyperparathyroidism.","authors":"L Solbiati,&nbsp;A Giangrande,&nbsp;G Montali,&nbsp;C Ravetto,&nbsp;C Bazzi,&nbsp;G Sorgato,&nbsp;T Ierace","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Parathyroid tumours were sonographically detected in 24 out of 72 uraemic patients with clinical and biochemical findings of secondary hyperparathyroidism. In 12 out of 24 cases ultrasonically guided fine-needle aspiration biopsy of the tumours was performed in order to obtain a cytological specimen. In the eight patients who subsequently had surgical exploration of the neck, diagnostic accuracy of both ultrasonography and biopsy combined was 87 per cent.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"293-7"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17928991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical implications of the presence of refractile particles in the liver of haemodialysis patients. 血液透析患者肝脏中存在折射性颗粒的临床意义。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
J M Morales, F Colina, J Arteaga, A Barrientos, V G Millet, L M Ruilope, J M Alcazar, J L Rodicio
{"title":"Clinical implications of the presence of refractile particles in the liver of haemodialysis patients.","authors":"J M Morales,&nbsp;F Colina,&nbsp;J Arteaga,&nbsp;A Barrientos,&nbsp;V G Millet,&nbsp;L M Ruilope,&nbsp;J M Alcazar,&nbsp;J L Rodicio","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a retrospective study we have examined 20 liver specimens from haemodialysis patients with a mean time on treatment of 27 months. Thirteen specimens were biopsies, the remaining came from autopsies. The presence of refractile particles was found in 55 per cent of biopsies and 100 per cent of autopsies. Its presence was not constantly associated with morphological lesions of the liver. We believe that the deposition of this material could be a fortuitous finding with uncertain clinical implications.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"19 ","pages":"265-9"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17257435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polyanionic inhibitors of calcium oxalate crystal agglomeration in urine. 尿中草酸钙结块的聚阴离子抑制剂。
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association Pub Date : 1983-01-01
D S Scurr, A B Latif, V Sergeant, W G Robertson
{"title":"Polyanionic inhibitors of calcium oxalate crystal agglomeration in urine.","authors":"D S Scurr,&nbsp;A B Latif,&nbsp;V Sergeant,&nbsp;W G Robertson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The excretions and relative potencies of various macromolecular inhibitors of the crystallisation of calcium oxalate (CaOx) were measured in the urines of idiopathic calcium stone-formers and normal subjects. The stone-formers excreted significantly less polyanionic macromolecules in their urine than did the normals, the difference being attributable to the lower excretions of glycosaminoglycans (GAGS), ribonucleic acid (RNA) and Tamm-Horsfall mucoprotein (THM), all of which are precipitable with alcian blue. The relative potencies of the various inhibitors measured under 'whole urine equivalent' conditions using a batch crystallisation system, showed that the order of inhibitory activity towards CaOx crystal agglomeration was RNA greater than GAGS greater than THM greater than pyrophosphate (PPi). This paralleled the order of ability of these inhibitors to produce a high negative zeta potential on the surface of CaOx crystals.</p>","PeriodicalId":76354,"journal":{"name":"Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association","volume":"20 ","pages":"440-4"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17261992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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