Pharmakopsychiatrie, Neuro-Psychopharmakologie最新文献_第8页

EEG profile studies of clozapine in volunteers and psychiatric patients. 氯氮平在志愿者和精神病患者中的脑电图研究。

Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-03-01 DOI: 10.1055/s-0028-1094609

M Fink, P Irwin, P Weinhold

引用次数: 18

Pharmaco-electroencephalography: the value of quantified EEG in psychopharmacology. 药物-脑电图:量化脑电图在精神药理学中的价值。

Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-03-01 DOI: 10.1055/s-0028-1094603

M Matejcek

引用次数: 17

EEG related to cerebral metabolism and blood flow. 脑电图与脑代谢和血流有关。

Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-03-01 DOI: 10.1055/s-0028-1094611

D H Ingvar, I Rosén, G Johannesson

{"title":"EEG related to cerebral metabolism and blood flow.","authors":"D H Ingvar, I Rosén, G Johannesson","doi":"10.1055/s-0028-1094611","DOIUrl":"https://doi.org/10.1055/s-0028-1094611","url":null,"abstract":"Summary It has long been known that the EEG relates in a general fashion to cerebral metabolism and blood flow. At an early stage it was found that, for example, comatous states with their slow wave EEG pattern showed a reduced cerebral metabolism and blood flow, as measured -with the Kety nitrous oxide technique. Vice versa, states with an increased metabolism, such as hyperthyroidism and epileptic seizures with a high frequency EEG pattern, showed an increased metabolism and blood flow. These observations suggested that the EEG carries information on the neuronal metabolic work and which in its turn controls the blood flow via the so-called metabolic regulation. The present opinion is that the EEG is ultimately determined by fluctuating rhythmic brain potentials in synchronized masses of neuro-pile in the cerebral cortex. These rhythmic chan-ges ultimately depend upon membrane activities involving ionic transport, which in its turn requires oxidative metabolism. Possibly the EEG thus reflects energy consuming processes in neuronal cortical membranes mainly in the so-called neuro-pile (Creutzfeldt). Recent studies of the frequency content of the human EEG have shown that it correlates distinctly to the over-all cerebral oxygen uptake as well as blood flow. Correlations between EEG and specific regions of the brain are also being studied. Thus, the normal waking state in undisturbed subjects, when the alpha rhythm shows its typical parieto-occipito-temporal distribution and higher frequencies frontally, is accompanied by a significant increase of the cerebral blood flow (and metabolism) in frontal areas and lower flows and metabolism in posterior regions. This state, which can be understood as a prerequisite for consciousness, has been interpreted as due to higher activities in efferent \"behavioural\" parts of the cerebral cortex and inhibition of afferent-gnostic regions where the alpha rhythm prevails. Results relating to this concept and also to regio-Zusammenhänge","PeriodicalId":76325,"journal":{"name":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","volume":"12 2","pages":"200-9"},"PeriodicalIF":0.0,"publicationDate":"1979-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0028-1094611","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11667355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 46

Statistical handling of EEG-data. 脑电图数据的统计处理。

Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-03-01 DOI: 10.1055/s-0028-1094612

T Gasser

引用次数: 1

The significance of personality traits in EEG evaluation of drug effects. 人格特征在脑电图药物疗效评价中的意义。

Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-03-01 DOI: 10.1055/s-0028-1094606

H J Heinze, H Künkel

引用次数: 5

Quantitative analysis of EEG's in epileptic patients. 癫痫患者脑电图的定量分析。

Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-03-01 DOI: 10.1055/s-0028-1094610

F H Lopes da Silva, A Kamp, N J Mars, G Bultstra, J G Lommen, K van Hulten

引用次数: 4

Reflections on the topics: EEG frequency bands and regulation of vigilance. 主题思考:脑电图频带和警觉性调节。

Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-03-01 DOI: 10.1055/s-0028-1094615

S Kubicki, W M Herrmann, K Fichte, G Freund

引用次数: 3

Drug-induced paroxysmal EEG-activities. 药物引起的阵发性脑电图活动。

Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-03-01 DOI: 10.1055/s-0028-1094607

J Kugler, E Lorenzi, R Spatz, H Zimmermann

引用次数: 22

Some methodological aspects on the statistical analysis of pharmaco-EEG data. 药物-脑电图数据统计分析的方法学问题。

Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-03-01 DOI: 10.1055/s-0028-1094613

U Ferner

引用次数: 3

Automatic measurement of the vigilance level and its possible application in psychopharmacology. 警觉性水平的自动测量及其在精神药理学中的应用。

Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-03-01 DOI: 10.1055/s-0028-1094605

M Matousek, I Petersen

{"title":"Automatic measurement of the vigilance level and its possible application in psychopharmacology.","authors":"M Matousek, I Petersen","doi":"10.1055/s-0028-1094605","DOIUrl":"https://doi.org/10.1055/s-0028-1094605","url":null,"abstract":"<p><p>The main object of the study was to separate the specific EEG effects of psychopharmaca from changes caused by drowsiness. The study was based on quantitative evaluation of the vigilance level during five minutes of EEG recording under standardized conditions. The equation for computing the vigilance level from EEG spectra was obtained by using a training material. The segments were classified visually either as alert EEG, or as EEG marked by drowsiness. As confirmed by independent test material, the coefficients derived by means of multiple linear regression were applicable to other EEGs for estimating the vigilance level. The procedure was used in the evaluation of the psychopharmacological treatment. It was concluded that the specific EEG drug profiles were certainly influenced by the accompanying drowsiness, but the main information was still preserved. In contrast to the specific drug effect, the drug-induced sleep activity could be isolated from other events and studied separately. It was also found that after a standard stimulation, both the general trend and periodicity of the vigilance fluctuations were closely related to the psychic state of the patient.</p>","PeriodicalId":76325,"journal":{"name":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","volume":"12 2","pages":"148-54"},"PeriodicalIF":0.0,"publicationDate":"1979-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0028-1094605","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11667351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16