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Pharmakopsychiatrie, Neuro-Psychopharmakologie最新文献

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Present state of the quantitative analysis of the EMG related to drug effectiveness. 肌电图与药物有效性的定量分析现状。
Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-01-01 DOI: 10.1055/s-0028-1094602
A Arrigo, A Moglia, G Sandrini, A Pernice
{"title":"Present state of the quantitative analysis of the EMG related to drug effectiveness.","authors":"A Arrigo, A Moglia, G Sandrini, A Pernice","doi":"10.1055/s-0028-1094602","DOIUrl":"https://doi.org/10.1055/s-0028-1094602","url":null,"abstract":"","PeriodicalId":76325,"journal":{"name":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","volume":"12 1","pages":"119-24"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0028-1094602","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11431638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amplitude histography of the EEG in psychopharmacological research. 脑电图振幅直方图在精神药理学研究中的应用。
Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-01-01 DOI: 10.1055/s-0028-1094599
H Rieger, J Krieglstein, H Schütz
{"title":"Amplitude histography of the EEG in psychopharmacological research.","authors":"H Rieger, J Krieglstein, H Schütz","doi":"10.1055/s-0028-1094599","DOIUrl":"https://doi.org/10.1055/s-0028-1094599","url":null,"abstract":"","PeriodicalId":76325,"journal":{"name":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","volume":"12 1","pages":"94-101"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0028-1094599","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11624283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
EEG and clinical profile of a synthetic analogue of methionine-enkephalin - FK 33-824. 蛋氨酸-脑啡肽- FK 33-824合成类似物的脑电图和临床特征。
Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-01-01 DOI: 10.1055/s-0028-1094598
E Krebs, J Roubicek
{"title":"EEG and clinical profile of a synthetic analogue of methionine-enkephalin - FK 33-824.","authors":"E Krebs, J Roubicek","doi":"10.1055/s-0028-1094598","DOIUrl":"https://doi.org/10.1055/s-0028-1094598","url":null,"abstract":"","PeriodicalId":76325,"journal":{"name":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","volume":"12 1","pages":"86-93"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0028-1094598","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11578028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
A comparative study of the effects of imipramine in normal subjects: power spectrum vs amplitude variance. 丙咪嗪对正常人影响的比较研究:功率谱与振幅方差。
Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-01-01 DOI: 10.1055/s-0028-1094595
L Goldstein
{"title":"A comparative study of the effects of imipramine in normal subjects: power spectrum vs amplitude variance.","authors":"L Goldstein","doi":"10.1055/s-0028-1094595","DOIUrl":"https://doi.org/10.1055/s-0028-1094595","url":null,"abstract":"","PeriodicalId":76325,"journal":{"name":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","volume":"12 1","pages":"69-73"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0028-1094595","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11624281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multichannel EEG preprocessing: analogue matrix operations in the study of local effects. 多通道脑电图预处理:模拟矩阵运算中局部效应的研究。
Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-01-01 DOI: 10.1055/s-0028-1094601
B Hjorth
{"title":"Multichannel EEG preprocessing: analogue matrix operations in the study of local effects.","authors":"B Hjorth","doi":"10.1055/s-0028-1094601","DOIUrl":"https://doi.org/10.1055/s-0028-1094601","url":null,"abstract":"","PeriodicalId":76325,"journal":{"name":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","volume":"12 1","pages":"111-8"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0028-1094601","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11625433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Progresses of statistical spectral analysis in pharmaco-electroencephalography. 药物脑电图统计谱分析研究进展。
Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1979-01-01 DOI: 10.1055/s-0028-1094600
P Etevenon, B Pidoux
{"title":"Progresses of statistical spectral analysis in pharmaco-electroencephalography.","authors":"P Etevenon, B Pidoux","doi":"10.1055/s-0028-1094600","DOIUrl":"https://doi.org/10.1055/s-0028-1094600","url":null,"abstract":"","PeriodicalId":76325,"journal":{"name":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","volume":"12 1","pages":"102-10"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0028-1094600","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11431637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Computer-aided classification and assessment of patients in multicenter trials. 多中心试验中患者的计算机辅助分类和评估。
Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1978-11-01 DOI: 10.1055/s-0028-1094587
G B Cassano, L Conti, P Castrogiovanni, J Levine
{"title":"Computer-aided classification and assessment of patients in multicenter trials.","authors":"G B Cassano,&nbsp;L Conti,&nbsp;P Castrogiovanni,&nbsp;J Levine","doi":"10.1055/s-0028-1094587","DOIUrl":"https://doi.org/10.1055/s-0028-1094587","url":null,"abstract":"<p><p>The automated diagnostic procedure appears to be particularly suitable for clinical psychopharmacological trials since it provides a diagnostic definition and a psychopathological profile of patients assessed by various investigators of different centers where a different kind of psychopathology as well as different cultural, clinical and psychopharmacological backgrounds may be present. Furthermore, this procedure offers the possibility of reexamining and analyzing the characteristics of the experimental sample as related to the responses to the drugs. It also provides a new approach for solving some of the problems which play an important role in determining divergent results in clinical psychopharmacology such as that of patients selection and diagnostic definition. In the present study the automated diagnostic procedure derived by the scores of each item of I.M.P.S. and by factor scores are evaluated comparatively. The data reported show that the automated diagnosis should be based on the scores of single aspects of the symptomatology rather than on the basis of the factor scores.</p>","PeriodicalId":76325,"journal":{"name":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","volume":"11 6","pages":"285-8"},"PeriodicalIF":0.0,"publicationDate":"1978-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0028-1094587","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11578025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A multidimensional test approach for the description of the CNS activity of drugs in human pharmacology. 人类药理学中药物中枢神经系统活性描述的多维测试方法。
Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1978-11-01 DOI: 10.1055/s-0028-1094585
W M Herrmann, R J McDonald
{"title":"A multidimensional test approach for the description of the CNS activity of drugs in human pharmacology.","authors":"W M Herrmann,&nbsp;R J McDonald","doi":"10.1055/s-0028-1094585","DOIUrl":"https://doi.org/10.1055/s-0028-1094585","url":null,"abstract":"<p><p>In a double-blind cross-over trial ten healthy male volunteers were administered placebo as well as one representative of each of the four hypothetical psychotropic drug classes, antipsychotics, antidepressants, anxiolytics, and psychostimulants. The drugs were: 75 mg of chlorpromazine, 75 mg of amitriptyline, 10 mg of diazepam and 18 mg of dextroamphetamine sulfate. The effects of the compounds were assessed by pharmaco EEG, an adjective checklist, and a battery of psychological performance tests. The results demonstrate that the test model differentiates well between sedative and stimulatory drug effects. In addition, this multidimensional test approach discriminates adequately the effects of the various sedative drugs. The advantages and limitations of multidimensional test approaches for the description of psychotropic drugs along with the importance of employing such an approach for the development of psychotropic drugs are discussed.</p>","PeriodicalId":76325,"journal":{"name":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","volume":"11 6","pages":"247-65"},"PeriodicalIF":0.0,"publicationDate":"1978-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0028-1094585","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11578026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
[Dopamine-receptor stimulators and neuroleptic-induced dyskinesia (author's transl)]. [多巴胺受体刺激剂和抗精神病药引起的运动障碍(作者译)]。
Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1978-11-01 DOI: 10.1055/s-0028-1094589
E Ringwald
{"title":"[Dopamine-receptor stimulators and neuroleptic-induced dyskinesia (author's transl)].","authors":"E Ringwald","doi":"10.1055/s-0028-1094589","DOIUrl":"https://doi.org/10.1055/s-0028-1094589","url":null,"abstract":"<p><p>We have examined bromocriptine, levodopa and trihexyphenydil ins ingle-blind design in 16 chronic productive schizophrenics having the same degree of tardive dyskinesias. Treatment time for each patient was 60 days: Bromocriptine was given in mean daily doses of 32 mg, levodopa 3,2 g and trihexyphenydil 27 mg. Bromocriptine and trihexyphenydil allowed the continued use of neuroleptics, without necessitating an increase in dosage. On the other hand, with levodopa 25% of the patients deteriorated, and this could not be prevented by increasing the dose of neuroleptics. Bromocriptine and trihexyphenydil permitted treatment of tardive dyskinesias, whereby bromocriptione was clinically (and statistically) superior to trihexyphenydil. Trihexyphenydil had only a slight effect on tremor, whilst treatment with levodopa was ineffective.</p>","PeriodicalId":76325,"journal":{"name":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","volume":"11 6","pages":"294-8"},"PeriodicalIF":0.0,"publicationDate":"1978-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0028-1094589","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11256568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Prejudices in pharmacology and pharmacotherapy: reserpine as a model for experimental research in depression. 药理学和药物治疗的偏见:利血平作为抑郁症实验研究的模型。
Pharmakopsychiatrie, Neuro-Psychopharmakologie Pub Date : 1978-11-01 DOI: 10.1055/s-0028-1094588
H J Bein
{"title":"Prejudices in pharmacology and pharmacotherapy: reserpine as a model for experimental research in depression.","authors":"H J Bein","doi":"10.1055/s-0028-1094588","DOIUrl":"https://doi.org/10.1055/s-0028-1094588","url":null,"abstract":"The choice of reserpine as practically the sole model substance used in research in depression over two decades was not dictated by rational considerations alone: hypothetical notions, prospects of the rapid realization of experimental research aims and the fascination of the exotic origin of this \"natural\" drug made a significant contribution.","PeriodicalId":76325,"journal":{"name":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","volume":"11 6","pages":"289-93"},"PeriodicalIF":0.0,"publicationDate":"1978-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0028-1094588","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11578027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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