Nihon Rai Gakkai zasshi最新文献_第8页

[Patients with calcinosis cutis in National Leprosarium Matsuoka Hoyo-En]. [国立麻风病医院皮肤钙质沉着症患者]。

Nihon Rai Gakkai zasshi Pub Date : 1992-07-01 DOI: 10.5025/hansen1977.61.98

K Ohtaka

{"title":"[Patients with calcinosis cutis in National Leprosarium Matsuoka Hoyo-En].","authors":"K Ohtaka","doi":"10.5025/hansen1977.61.98","DOIUrl":"https://doi.org/10.5025/hansen1977.61.98","url":null,"abstract":"As of the year 1991 there were 358 leprosy patients in National Leprosarium Matsuoka Hoyo-En, including 223 patients (62.3%) who had received the injections of chaulmoogra oil before. Calcinosis cutis caused probably from the injections was noted on 73 patients (32.7%): 67 lepromatous and 6 tuberculosis cases. It has never been reported before that the T type patient suffering from calcinosis cutis was observed in the cases of the chaulmoogra oil injection in Japan. The detectable positions of calcinosis cutis were mostly at the injected sites, that is, outside the right brachium followed by bilateral-branchia and crura. In the group of patients with calcinosis cutis, the anti-PGL antibody was negative for the most part. Urinalyses, peripheral blood figure analyses, histopathological tissue examinations of calcium deposition, X-ray diffraction patterns, differential thermal and gravitational analyses, and chemical analyses were performed on all patients with this disease. Further, as the result of this study six patients with calcinosis cutis caused by sulpyrine was also found. The major component of the deposit by the drug was calcium phosphate. These calcinosis cutis were considered to be of trophopathic calcinosis based on the disorder of subcutaneous tissue due to the injections of respective drugs: chaulmoogra oil and sulpyrine.","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"61 2","pages":"98-101"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12656814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

[Monokine production by mouse peritoneal macrophages after phagocytosis of mycobacteria]. 小鼠腹腔巨噬细胞吞噬分枝杆菌后产生的单因子。

Nihon Rai Gakkai zasshi Pub Date : 1992-07-01 DOI: 10.5025/hansen1977.61.92

Y Fukutomi, S Inui, K Onozaki

{"title":"[Monokine production by mouse peritoneal macrophages after phagocytosis of mycobacteria].","authors":"Y Fukutomi, S Inui, K Onozaki","doi":"10.5025/hansen1977.61.92","DOIUrl":"https://doi.org/10.5025/hansen1977.61.92","url":null,"abstract":"It is well known that monokines, IL-1 (Interleukin-1) and TNF (Tumor Necrosis Factor), are produced by macrophages after stimulated with various agents. These cytokines are involved in various aspects of the inflammatory process and immunological response in addition to their original activities to proliferate T lymphocytes and causing tumor necrosis, respectively. Recently, there have been reported that IL-1 and TNF also play an important role in mycobacterial infections such as granuloma formation. In the present study, IL-1 and TNF productions were observed by mouse peritoneal exudate and resident macrophages after incubation with heat-killed M. lepraemurium and M. avium in vitro. The production was enhanced by phagocytosis of these mycobacteria in a dose dependent manner, and the time course of the production was maximum within 24 hr after phagocytosis of these mycobacteria. It was also shown of morphological changes and enhanced glucose consumption in media by these macrophages. Above results suggest that phagocytosis of mycobacteria by macrophages leads to monokine production, which would not only causes well known immunological reactions but also makes characteristic phenomena to be observed in mycobacterial infections.","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"61 2","pages":"92-7"},"PeriodicalIF":0.0,"publicationDate":"1992-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12656813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

[Successful handling of a patient in advanced age in the National Leprosarium Kikuchi Keifu-En with a case of delusion of being robbed]. 【在国立麻风医院成功处理一例被抢劫妄想的高龄病人】。

Nihon Rai Gakkai zasshi Pub Date : 1992-07-01 DOI: 10.5025/hansen1977.61.104

M Murakami, Y Mizushima, C Irisawa

引用次数: 0

[Bacteriology of Mycobacterium leprae: from the gene technological viewpoint]. 麻风分枝杆菌的细菌学:从基因技术的角度。

Nihon Rai Gakkai zasshi Pub Date : 1992-07-01 DOI: 10.5025/hansen1977.61.73

M Makino, Y Suzuki

引用次数: 0

[Memories on the investigation of leprosy of the upper respiratory tract]. [关于上呼吸道麻风病调查的回忆]。

Nihon Rai Gakkai zasshi Pub Date : 1992-01-01 DOI: 10.5025/hansen1977.61.102

Y. Yoshino