Nihon Rai Gakkai zasshi最新文献

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[Intensive summer college on Hansen's disease]. [汉森氏病强化暑期学院]。
Nihon Rai Gakkai zasshi Pub Date : 1995-07-01
K Murakami
{"title":"[Intensive summer college on Hansen's disease].","authors":"K Murakami","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 2","pages":"132-3"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18597454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Leprosy in Japan]. [日本的麻风病]。
Nihon Rai Gakkai zasshi Pub Date : 1995-07-01
N Ishii
{"title":"[Leprosy in Japan].","authors":"N Ishii","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 2","pages":"89-92"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18597458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Recent development in immunology of leprosy: roles of immunoregulatory cytokines in the establishment of immuno-unresponsiveness to M. leprae in leprosy patients]. 麻风病免疫学的最新进展:免疫调节细胞因子在麻风病患者对麻风分枝杆菌免疫无反应的建立中的作用。
Nihon Rai Gakkai zasshi Pub Date : 1995-07-01
H Tomioka
{"title":"[Recent development in immunology of leprosy: roles of immunoregulatory cytokines in the establishment of immuno-unresponsiveness to M. leprae in leprosy patients].","authors":"H Tomioka","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 2","pages":"69-84"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18597456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Leprosy control]. (麻风控制)。
Nihon Rai Gakkai zasshi Pub Date : 1995-07-01
S Okada
{"title":"[Leprosy control].","authors":"S Okada","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 2","pages":"67-8"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18597455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytokine responses in leprosy lesions. 麻风病病变的细胞因子反应。
Nihon Rai Gakkai zasshi Pub Date : 1995-07-01 DOI: 10.5025/hansen1977.64.85
R L Modlin
{"title":"Cytokine responses in leprosy lesions.","authors":"R L Modlin","doi":"10.5025/hansen1977.64.85","DOIUrl":"https://doi.org/10.5025/hansen1977.64.85","url":null,"abstract":"<p><p>The clinical spectrum of leprosy reflects the diverse nature of human immune responses to Mycobacterium leprae. The clinical presentations correlate with the level of cell-mediated immunity against M. leprae. Cell-mediated immunity, as assessed by the Mitsuda reaction, is positive in tuberculoid patients and negative in lepromatous patients. In contrast, humoral immunity, as assessed by anti-M. leprae antibodies is greatest in lepromatous patients. The inverse correlation between cell-mediated immunity can be explained on the basis of the local cytokine pattern.</p>","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 2","pages":"85-8"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18597457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
[HLA-DR2 alleles and uveitis in leprosy]. [HLA-DR2等位基因与麻风病葡萄膜炎]。
Nihon Rai Gakkai zasshi Pub Date : 1995-07-01
S Joko, J Numaga, Y Fujino, K Masuda, R Hirata, H Maeda
{"title":"[HLA-DR2 alleles and uveitis in leprosy].","authors":"S Joko,&nbsp;J Numaga,&nbsp;Y Fujino,&nbsp;K Masuda,&nbsp;R Hirata,&nbsp;H Maeda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In order to investigate the role of immunogenetic factors in the pathogenesis of uveitis in leprosy, HLA antigens were analyzed between the leprotics with and without uveitis. Sixty-five Japanese leprosy patients comprised 32 with uveitis and 33 without uveitis. Controls consisted of 138 healthy subjects. A lymphocyte cytotoxicity test was used for typing HLA-A, -B, -C, -DR and -DQ antigens. HLA-DR2 genotyping was performed by the polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) and PCR-restriction fragment length polymorphism (RFLP) methods. The frequency of HLA-DR2 antigen was significantly increased in the patients with uveitis as compared with the control subjects (Pc < 0.0005), whereas HLA-DR53 antigen was significantly decreased (Pc < 0.05). At the genomic level the frequency of HLA-DRB1*1501 was significantly increased in the patients with uveitis and without uveitis as compared with that in the controls. The association with DRB1*1501 was even stronger in patients with uveitis (odds ratio = 7.1, Pc < 0.000005) than in the patients without uveitis (odds ratio = 4.1, Pc < 0.005). Our results suggest that HLA-DRB1*1501 contribute to the susceptibility to uveitis in the Japanese with leprosy.</p>","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 2","pages":"112-8"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18597519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The present conditions and the future measure at national leprosaria in Japan. 日本全国麻风现状及未来措施。
Nihon Rai Gakkai zasshi Pub Date : 1995-07-01 DOI: 10.5025/hansen1977.64.93
E Nagao
{"title":"The present conditions and the future measure at national leprosaria in Japan.","authors":"E Nagao","doi":"10.5025/hansen1977.64.93","DOIUrl":"https://doi.org/10.5025/hansen1977.64.93","url":null,"abstract":"","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 2","pages":"93-9"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18597459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[HLA-DR2 alleles and uveitis in leprosy]. [HLA-DR2等位基因与麻风病葡萄膜炎]。
Nihon Rai Gakkai zasshi Pub Date : 1995-07-01 DOI: 10.5025/HANSEN1977.64.112
S. Joko, J. Numaga, Y. Fujino, K. Masuda, R. Hirata, H. Maeda
{"title":"[HLA-DR2 alleles and uveitis in leprosy].","authors":"S. Joko, J. Numaga, Y. Fujino, K. Masuda, R. Hirata, H. Maeda","doi":"10.5025/HANSEN1977.64.112","DOIUrl":"https://doi.org/10.5025/HANSEN1977.64.112","url":null,"abstract":"In order to investigate the role of immunogenetic factors in the pathogenesis of uveitis in leprosy, HLA antigens were analyzed between the leprotics with and without uveitis. Sixty-five Japanese leprosy patients comprised 32 with uveitis and 33 without uveitis. Controls consisted of 138 healthy subjects. A lymphocyte cytotoxicity test was used for typing HLA-A, -B, -C, -DR and -DQ antigens. HLA-DR2 genotyping was performed by the polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) and PCR-restriction fragment length polymorphism (RFLP) methods. The frequency of HLA-DR2 antigen was significantly increased in the patients with uveitis as compared with the control subjects (Pc < 0.0005), whereas HLA-DR53 antigen was significantly decreased (Pc < 0.05). At the genomic level the frequency of HLA-DRB1*1501 was significantly increased in the patients with uveitis and without uveitis as compared with that in the controls. The association with DRB1*1501 was even stronger in patients with uveitis (odds ratio = 7.1, Pc < 0.000005) than in the patients without uveitis (odds ratio = 4.1, Pc < 0.005). Our results suggest that HLA-DRB1*1501 contribute to the susceptibility to uveitis in the Japanese with leprosy.","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"43 1","pages":"112-8"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88903191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Leprosy patients and hallux valgus--first report. 麻风病患者和拇外翻——首次报道。
Nihon Rai Gakkai zasshi Pub Date : 1995-07-01 DOI: 10.5025/hansen1977.64.105
T Tozawa, Y Kuramatsu, J Nakata, M Narita
{"title":"Leprosy patients and hallux valgus--first report.","authors":"T Tozawa,&nbsp;Y Kuramatsu,&nbsp;J Nakata,&nbsp;M Narita","doi":"10.5025/hansen1977.64.105","DOIUrl":"https://doi.org/10.5025/hansen1977.64.105","url":null,"abstract":"たまたま保存されていた1910年より1951年にいたる医学的研究の資料の中から,特に足部を撮影した写真乾板38枚(54例96足)を選び出し,外反母趾の合併の有無を調べてみた。その結果,一応外反母趾と指摘できたのはわずかに6例7足であり,これらから足穿孔症などに続発した第1中足骨骨頭の破壊によるらしいものを除くと2例3足に過ぎず,それも軽度かやや中等度に近い状態であるから,治療の対象にはまずならないにちがいない。このように過去においては,現在よりも,外反母趾の発症がはるかに少なかったらしく,その理由は下駄や草履を主に履いていたためであろうが,包帯の巻き方もこれらを履きやすいように工夫されていた。故に外反母趾の発生には,少なくともらい患者に限っては履物などによる外因性要素を第一義的に考えたい。","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 2","pages":"105-11"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5025/hansen1977.64.105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18597518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[New technique: PCR method for diagnosis of patients with leprosy]. 【新技术:PCR法诊断麻风病】。
Nihon Rai Gakkai zasshi Pub Date : 1995-07-01
Y Sugita
{"title":"[New technique: PCR method for diagnosis of patients with leprosy].","authors":"Y Sugita","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 2","pages":"100-4"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18597517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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