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[Infection and cytokine]. [感染和细胞因子]。
Nihon Rai Gakkai zasshi Pub Date : 1995-11-01 DOI: 10.5025/hansen1977.64.149
K Onozaki
{"title":"[Infection and cytokine].","authors":"K Onozaki","doi":"10.5025/hansen1977.64.149","DOIUrl":"https://doi.org/10.5025/hansen1977.64.149","url":null,"abstract":"","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 3","pages":"149-62"},"PeriodicalIF":0.0,"publicationDate":"1995-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19562437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Present and future in leprosy research]. [麻风病研究的现状与未来]。
Nihon Rai Gakkai zasshi Pub Date : 1995-11-01 DOI: 10.5025/hansen1977.64.200
H Saito, Y Kashiwabara
{"title":"[Present and future in leprosy research].","authors":"H Saito, Y Kashiwabara","doi":"10.5025/hansen1977.64.200","DOIUrl":"https://doi.org/10.5025/hansen1977.64.200","url":null,"abstract":"","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 3","pages":"200-13"},"PeriodicalIF":0.0,"publicationDate":"1995-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19562441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Uveitis in leprosy patients]. [麻风病患者的葡萄膜炎]。
Nihon Rai Gakkai zasshi Pub Date : 1995-11-01 DOI: 10.5025/hansen1977.64.230
M Namisato, K Morii, S Asami, A Haraya, S Joko, K Kawatsu, S Izumi, H Ogawa
{"title":"[Uveitis in leprosy patients].","authors":"M Namisato,&nbsp;K Morii,&nbsp;S Asami,&nbsp;A Haraya,&nbsp;S Joko,&nbsp;K Kawatsu,&nbsp;S Izumi,&nbsp;H Ogawa","doi":"10.5025/hansen1977.64.230","DOIUrl":"https://doi.org/10.5025/hansen1977.64.230","url":null,"abstract":"<p><p>We examined 24 dermatologically cured leprosy patients with ongoing uveitis (UV+) and 22 age and type matched controls (UV-) to study the late phase leprous UV. All patients have been skin smear negative for more than 10 years. The history of chemotherapy, 5 years before and after a accomplishing bacterial negativity, was evaluated and represented by \"SCORE\". It was found that anti-PGL-I and anti-LAM-B antibodies were significantly higher in UV+ group compared to the controls. The mean SCORE of chemotherapy in UV+ group was significantly lower than in the controls. Iris pearls were seen in 10 cases or 42% out of 24 UV+ patients. No iris pearls were seen in control group. These results suggest that insufficient chemotherapy and consequent incomplete elimination of bacilli are the risk factors for leprous UV in the quiescent stage of the disease.</p>","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 3","pages":"230-5"},"PeriodicalIF":0.0,"publicationDate":"1995-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19562444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Progress and impact of multidrug therapy (MDT) implementation to leprosy control in Thailand. 泰国实施多药治疗对麻风病控制的进展和影响。
Nihon Rai Gakkai zasshi Pub Date : 1995-11-01 DOI: 10.5025/hansen1977.64.214
P Ramasoota, T Intaratitaya
{"title":"Progress and impact of multidrug therapy (MDT) implementation to leprosy control in Thailand.","authors":"P Ramasoota,&nbsp;T Intaratitaya","doi":"10.5025/hansen1977.64.214","DOIUrl":"https://doi.org/10.5025/hansen1977.64.214","url":null,"abstract":"<p><p>This paper report the progress and impact of MDT implementation to leprosy control in Thailand since 1984 until 1994. By ten years of MDT implementation, number of registered cases dropped from 44,406 in 1984 to only 4,878 cases in 1994. Which made prevalence rate declined 90% from 8.8 to 0.83 per 10,000 population, the detection rate of new case declined from 6.2 to 1.97 per 100,000 population. Total 39,372 cases have been completely covered by MDT and 22,821 cases are under post MDT surveillance with the low relapse rate only 1.46% other indicators showing natural decline of leprosy were increasing in proportion of multibacillary leprosy and mean age at onset of new case of leprosy together with decreasing in proportion of children among new case. Other impact of MDT showing increasing trend of proportion of new case of patient who voluntarily attend treatment centers. However, there were still no satisfactory impact on decreasing in proportion of deformity and duration since onset to the first detection of new case of leprosy.</p>","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 3","pages":"214-9"},"PeriodicalIF":0.0,"publicationDate":"1995-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5025/hansen1977.64.214","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19562442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
[Leprosy and vaccine]. [麻风病和疫苗]
Nihon Rai Gakkai zasshi Pub Date : 1995-11-01 DOI: 10.5025/hansen1977.64.163
S Matsumoto, T Yamada
{"title":"[Leprosy and vaccine].","authors":"S Matsumoto,&nbsp;T Yamada","doi":"10.5025/hansen1977.64.163","DOIUrl":"https://doi.org/10.5025/hansen1977.64.163","url":null,"abstract":"","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 3","pages":"163-73"},"PeriodicalIF":0.0,"publicationDate":"1995-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19562438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The dermal connective tissue of long quiescent leprosy patients. Part 2. Comparison of the volumes of collagen with those of elastic fibers]. 长时间静止的麻风病患者皮肤结缔组织。第2部分。胶原蛋白体积与弹性纤维体积的比较]。
Nihon Rai Gakkai zasshi Pub Date : 1995-11-01 DOI: 10.5025/hansen1977.64.220
M Namisato, K Kameyama, M Yajima, G Asano
{"title":"[The dermal connective tissue of long quiescent leprosy patients. Part 2. Comparison of the volumes of collagen with those of elastic fibers].","authors":"M Namisato,&nbsp;K Kameyama,&nbsp;M Yajima,&nbsp;G Asano","doi":"10.5025/hansen1977.64.220","DOIUrl":"https://doi.org/10.5025/hansen1977.64.220","url":null,"abstract":"<p><p>We studied dermal connective tissue of leprosy patients(Pa) in inactive condition. The dermal thickness(D) and the volumes of collagen and elastic fibers were measured utilizing automated computerized image analyzer. The length of each elastic fibers(E) in lower legs were also measured. The E in upper dermis of forearms were observed microscopically. All these were compared with age-matched control(Co). We got the following results accordingly. There was a relative increase of E in Pa's limb skin in spite of greatly decreased dermal thickness and fibrous components. The influence of sun exposure could not be recognized in this result. Each elastic fibers of Pa were longer than that of Co. The increased E in upper dermis was evident in Co's forearms, but not in Pa's. From our results, it is conceivable that the Pa's E either outlast or are overproduced exceedingly the collagen fibers. The factors that may account for these results are remained to be clarified.</p>","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 3","pages":"220-9"},"PeriodicalIF":0.0,"publicationDate":"1995-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19562443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Present status of studies on antileprosy drugs]. [抗麻风药物的研究现状]。
Nihon Rai Gakkai zasshi Pub Date : 1995-11-01 DOI: 10.5025/hansen1977.64.174
M Gidoh, H Saito
{"title":"[Present status of studies on antileprosy drugs].","authors":"M Gidoh,&nbsp;H Saito","doi":"10.5025/hansen1977.64.174","DOIUrl":"https://doi.org/10.5025/hansen1977.64.174","url":null,"abstract":"","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 3","pages":"174-87"},"PeriodicalIF":0.0,"publicationDate":"1995-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19562439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Intraepidermal mass of M. leprae in a case of seborrheic keratosis due to Hansen's disease (LLs)]. [麻风分枝杆菌表皮内肿物在汉森病(LLs)引起的脂溢性角化病1例]。
Nihon Rai Gakkai zasshi Pub Date : 1995-11-01 DOI: 10.5025/hansen1977.64.236
M Yajima, K Suzuki, M Wen, N Yamada, G Asano
{"title":"[Intraepidermal mass of M. leprae in a case of seborrheic keratosis due to Hansen's disease (LLs)].","authors":"M Yajima,&nbsp;K Suzuki,&nbsp;M Wen,&nbsp;N Yamada,&nbsp;G Asano","doi":"10.5025/hansen1977.64.236","DOIUrl":"https://doi.org/10.5025/hansen1977.64.236","url":null,"abstract":"<p><p>A 67-year-old patient has had exanthema in the lower right limb since 51 years ago (16 years old at onset), which underwent repeated remission and recurrence. At present, he has bilateral symmetrical widespread infiltrating exanthema and asymmetrical marked neuralhypertrophy, and has been diagnosed typical LLs (His father had the same disease). The exanthema recurred several years ago, and the patient is being treated for Hansen's disease. He had a dark brown flat elevation with a rough surface and the size of a small finger tip in his right abdominal skin for approximately 20 years. A biopsy was performed, and the specimen was fixed in 10% formalin and paraffin sections were prepared for histopathologic examination. A part of the specimen was processed forscanning electron microscopic examination. Seborrheic keratosis was diagnosed by H & E staining. Acid-fast (FITE) staining, immunohistochemical staining (keratin, S-100 protein, anti-PGL antibody and anti-BCG antibody) and scanning electron microscopy revealed the presence of bacteria (M. leprae) in the dermal foam cells, the matrix with a banded structure and the squamous epithelial cells which normally lack phagocytosis function. Compared to the basal cells of normal epidermis, the basal cells located adjacent to the dermis affected with seborrheic keratosis showed increased proliferation and more marked characteristics of a germinative cell. The degree of differentiation of the basal cells appeared regressed, and they probably possessed augmented phagocytic activity. The phagocytosed bacteria were probably carried by the epidermal cell cycle toward the surface layer. However, bacteria could not be found in the stratum corneum, probably due to an association with the lysosome.</p>","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 3","pages":"236-45"},"PeriodicalIF":0.0,"publicationDate":"1995-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5025/hansen1977.64.236","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19562445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Inoculum sizes necessary for maintaining the activity of Mycobacterium leprae in cell-free liquid media]. [在无细胞液体培养基中维持麻风分枝杆菌活性所需的接种量]。
Nihon Rai Gakkai zasshi Pub Date : 1995-07-01 DOI: 10.5025/hansen1977.64.119
M Nakamura
{"title":"[Inoculum sizes necessary for maintaining the activity of Mycobacterium leprae in cell-free liquid media].","authors":"M Nakamura","doi":"10.5025/hansen1977.64.119","DOIUrl":"https://doi.org/10.5025/hansen1977.64.119","url":null,"abstract":"<p><p>Evidence was presented in the previous paper that the activity of cells of Mycobacterium leprae was maintained in the phosphate buffer(pH 7) containing fetal calf serum (10%) with/without glycerin (2%) for approximately 4 weeks during incubation of cells at 30 degrees C, when the inoculum having more than 3,000 pg ATP was used. In the present paper, it is confirmed that the definite inoculum sizes are essential for obtaining the reproducible results that are described above, by using the inocula containing more and less than 3,000 pg ATP.</p>","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 2","pages":"119-23"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18597452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Recent improvement in histopathological technique]. [组织病理学技术的最新进步]。
Nihon Rai Gakkai zasshi Pub Date : 1995-07-01
K Kawatsu
{"title":"[Recent improvement in histopathological technique].","authors":"K Kawatsu","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76236,"journal":{"name":"Nihon Rai Gakkai zasshi","volume":"64 2","pages":"124-31"},"PeriodicalIF":0.0,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18597453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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