Leprosy in India最新文献

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Central serous retinopathy in leprosy. 麻风病的中枢性浆液性视网膜病变。
Leprosy in India Pub Date : 1983-04-01
P A Lamba, R Srinivasan
{"title":"Central serous retinopathy in leprosy.","authors":"P A Lamba,&nbsp;R Srinivasan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The involvement of fundus is rare in leprosy. More so fundus lesions, if any, are not very well visualized because of anterior segment lesions and the pupillary adhesions. A case of central serous retinopathy is recorded in association with progressive lepra reaction (type II) in a case of leprosy.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 2","pages":"209-11"},"PeriodicalIF":0.0,"publicationDate":"1983-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17687786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paper spot test and DDS/creatinine ratios in relation to treatment taken by leprosy patients. 麻疯病人纸片斑点试验及DDS/肌酐比值与治疗的关系。
Leprosy in India Pub Date : 1983-04-01
S Balakrishnan, A Kumar, J A Rozario, M Thiagarajan, P Sirumban
{"title":"Paper spot test and DDS/creatinine ratios in relation to treatment taken by leprosy patients.","authors":"S Balakrishnan,&nbsp;A Kumar,&nbsp;J A Rozario,&nbsp;M Thiagarajan,&nbsp;P Sirumban","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The findings on the positivity of paper spot test and the mean DDS/Cr. ratios in relation to the percentage of treatment taken by 316 leprosy out-patients on 100, 50 or 25 mg/DDS daily are presented. Thirty-three percent of the subjects on 25 mg were found to give negative spot test as against 11-12% in the patient groups on 50 and 100 mgs dose schedules. The mean DDS/Cr. ratios in the spot test negative urine specimens were consistent for all dosage groups and ranged from 7.1-9.6 micrograms/mg. The ratios in the spot test-positive urine specimens, showed, in general, a direct proportion to the percentage of treatment taken particularly, in the 75-100% and 50-75% groups. The significance and implications of the findings are discussed.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 2","pages":"231-6"},"PeriodicalIF":0.0,"publicationDate":"1983-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17687788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leprosy--a case for mental health care. 麻风病——精神卫生保健的一个案例。
Leprosy in India Pub Date : 1983-04-01
B C Mhasawade
{"title":"Leprosy--a case for mental health care.","authors":"B C Mhasawade","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One hundred twenty institutionalized cases of leprosy were tested for anxiety and depression on standard scales before and after psychiatric treatment. The latter seems to be effective in reducing both anxiety and depression after a course of treatment of three months. This appears to be a sound justification to advocate mental health care in institutions of leprosy in conjunction with physical care. Leprosy is a chronic and disabling disease entity. With the social stigma associated to the disease the psychiatric hazards of the disease are as bad as its physical manifestations. However, usually, only the latter attract attention. Ignorance about the disease and social values about the disease can at once land a person in depression on utterance of the diagnosis. Further, anxiety about the outcome of the disease in particular and future in general are known to exist in sufferers of leprosy.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 2","pages":"310-3"},"PeriodicalIF":0.0,"publicationDate":"1983-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17687573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Socio-economic experiences of leprosy patients. 麻风病患者的社会经济经历。
Leprosy in India Pub Date : 1983-04-01
A Kumar, M Anbalagan
{"title":"Socio-economic experiences of leprosy patients.","authors":"A Kumar,&nbsp;M Anbalagan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>225 adult leprosy patients were interviewed to study their socio-economic experiences, about various aspects of their lives. It was observed that 17.34%, 14.33% and 45.78% of patients experienced negative reactions from their families, spouses and society members, respectively. Out of 79 unmarried patients, 53 (67.1%) attributed leprosy as the only reason for not getting a partner for marriage. Out of 146 married patients, 34 (23.3%) were not living with their spouses; this also included 9 (6.2%) patients, deserted by their partners. Leprosy uprooted 44 (13.55%) patients from their residences, of whom 27 settled in leprosy village/settlement. The occupational status of 104 (46.22%) patients was adversely affected due to leprosy, of whom 43 became dependents and 17 beggars. Monthly income of 115 (51.1%) patients reduced to the extent of 84%, after getting leprosy. The social prejudice and deformities due to leprosy, have played key roles in socio-economic deterioration of patients. The leprosy control programme (LCP) need to be implemented more efficiently and effectively, with active involvement of communities. The socio-medical units, if included in LCP, may be utilized more effectively to prevent the socio-economic dehabilitation of patients, as well to tackle the abnormal psycholygical behaviours of patients.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 2","pages":"314-21"},"PeriodicalIF":0.0,"publicationDate":"1983-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17687574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of one year clofazimine therapy on autonomic functions in lepromatous leprosy with lepra (ENL) reaction. 氯法齐明治疗1年对麻风性麻风伴麻风反应自主神经功能的影响。
Leprosy in India Pub Date : 1983-04-01
N P Burte, A G Chandorkar, M P Muley, J J Balsara, P M Bulakh
{"title":"Effect of one year clofazimine therapy on autonomic functions in lepromatous leprosy with lepra (ENL) reaction.","authors":"N P Burte,&nbsp;A G Chandorkar,&nbsp;M P Muley,&nbsp;J J Balsara,&nbsp;P M Bulakh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Twenty patients of either sex of Lepromatous leprosy with frequent type II (ENL) reactions were selected for the study after exclusion of autonomic disorders. ANS functions were evaluated before and after Clofazimine therapy at an interval of two months for one year. Sweat function test, valsalva manoeuvre, Histamine triple response, cold pressor test and Homatropine instillation were carried out in twenty normal healthy volunteers (controls) and the (ENL) patients. Clofazimine was administered initially 100 mg three times daily for one month and then gradually reduced to a dose of 100 mg biweekly for the last three months. Before the clofazimine therapy, eighteen patients had abnormal sweat functions, five patients had abnormal valsalva score, five patients had abnormal cold pressor response and all the eighteen patients had abnormal histamine triple response test. Homatropine instillation test was normal in all the patients. ANS functions did not improve significantly with Clofazimine therapy, except in one patients with abnormal cold pressor response who showed slight improvement in pressor response which, however, did not reach the normal value. ANS function tests indicate complete involvement of local axon reflex and hyporeactivity of sympathetic system and cardiac regulatory mechanisms in these patients. Parasympathetic system seems to be normal as seen from Homatropine instillation test.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 2","pages":"278-85"},"PeriodicalIF":0.0,"publicationDate":"1983-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17744297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Observations on the cultivation of M. leprae in medium 'V' (Veeraraghavan). “V”培养基(Veeraraghavan)培养麻风分枝杆菌的观察。
Leprosy in India Pub Date : 1983-04-01
V M Katoch, K V Desikan
{"title":"Observations on the cultivation of M. leprae in medium 'V' (Veeraraghavan).","authors":"V M Katoch,&nbsp;K V Desikan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The medium 'V' has been evaluated for the in vitro growth of M. leprae. M. leprae were obtained from five untreated cases of multibacillary type of leprosy. Medium was prepared and inoculated by the method described by Veeraraghavan. Killed (Autoclaved) M. leprae from the same biopsies were kept as controls. Growth was monitored in a double blind manner at 60 hours, 120 hours of incubation at 8-10 degrees C of both primary and subcultures. Counting was done by both standard Shepard and McRae method as well as by Veeraraghavan's method. There was no evidence of any multiplication in any of the cases at 60 and 120 hours of incubation.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 2","pages":"292-8"},"PeriodicalIF":0.0,"publicationDate":"1983-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17416049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nerve abscess in a deep seated branch of medial plantar nerve in the foot. 足底内侧神经深支神经脓肿。
Leprosy in India Pub Date : 1983-04-01
S Hussain, G N Malaviya, B K Girdhar
{"title":"Nerve abscess in a deep seated branch of medial plantar nerve in the foot.","authors":"S Hussain,&nbsp;G N Malaviya,&nbsp;B K Girdhar","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 2","pages":"371"},"PeriodicalIF":0.0,"publicationDate":"1983-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17374863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acid mucopolysaccharides in leprosy lesions. 麻风病变中的酸性粘多糖。
Leprosy in India Pub Date : 1983-04-01
R Sakuntala, V K Pratap, N K Sharma, S S Dayal
{"title":"Acid mucopolysaccharides in leprosy lesions.","authors":"R Sakuntala,&nbsp;V K Pratap,&nbsp;N K Sharma,&nbsp;S S Dayal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Uniform accumulation of acid mucopolysaccharides in all types of leprosy lesions was seen, except late tuberculoid lesions which showed the accumulation only at the periphery. Absence of acid mucopolysaccharides was significant in well formed epithelioid granulomas and in giant cells of late tuberculoid cases. Generally a progressive decrease with advancing chronicity of the disease was noted. The dermal zone without any cellular infiltrate showed abundant acid mucopolysaccharides in comparison to those areas having inflammatory cell infiltrate in 70.83% of LL, 42.86% of BL, 33.3% of BB, 40.0% of BT, and 13.51% of TT cases. In Indeterminate cases the distribution was same to that of control cases. Testicular hyaluronidase digestion established that hyaluronic acid constituted the main bulk of acid mucopolysaccharides. The possible source of hyaluronic acid is discussed.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 2","pages":"252-60"},"PeriodicalIF":0.0,"publicationDate":"1983-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17290831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clofazimine in lepra (ENL) reaction, one year clinical trial. 氯法齐明治疗lepra (ENL)反应,一年临床试验。
Leprosy in India Pub Date : 1983-04-01
N P Burte, A G Chandorkar, M P Muley, J J Balsara, P M Bulakh
{"title":"Clofazimine in lepra (ENL) reaction, one year clinical trial.","authors":"N P Burte,&nbsp;A G Chandorkar,&nbsp;M P Muley,&nbsp;J J Balsara,&nbsp;P M Bulakh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Twenty patients of lepromatous leprosy with lepra reaction and suspected dapsone resistance were treated with tapering doses of clofazimine. Clinical assessment was carried out every week. Bacteriological examination was carried out every six month. Fifteen patients became reaction free at the end of three months and severity and frequency of reactions was reduced in other patients. Nerve tenderness, arthralgia, nodular eruptions and all other signs and symptoms except anaesthesia showed complete recovery in fifteen patients and severity of the reactions was reduced in others. Gynaecomastia regressed in two out of three patients within nine months. In a majority of patients, the BI and MI was reduced at the end of 3 months, and further reduced after 6 months, and in one case both BI and MI became negative. Clinical and bacteriological improvement is attributed to the antibacterial effect of clofazimine while reduction in incidence of (ENL) reactions was attributed to anti-inflammatory effect of clofazimine. Regression of gynaecomastia may be due to either improvement of involvement of testes or liver or both. Apart from dyschromia clofazimine did not produce any severe side effects or toxicity.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 2","pages":"265-77"},"PeriodicalIF":0.0,"publicationDate":"1983-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17416048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatitis-B virus infection in patients with leprosy--a brief communication. 麻风病患者乙型肝炎病毒感染——简短交流
Leprosy in India Pub Date : 1983-04-01
V M Katoch, K Katoch, A K Dutta, V D Sharma, G Ramu
{"title":"Hepatitis-B virus infection in patients with leprosy--a brief communication.","authors":"V M Katoch,&nbsp;K Katoch,&nbsp;A K Dutta,&nbsp;V D Sharma,&nbsp;G Ramu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The prevalence rate of hepatitis-B surface antigen (HBsAg) were determined in 413 patients of different types of leprosy and 133 healthy controls from the same population, in a study undertaken over a period of more than 3 years. The average frequency of australia antigen (HBsAg) was 7.7% in leprosy cases as compared to 6.0% in their healthy counterparts. Across the spectrum 7.2% of lepromatous patients (LL); 8.5% of borderline lepromatous (BL); 9.1% of borderline borderline (BB); 8.6% of borderline tuberculoid (BT) and 8.8% of tuberculoid (TT) cases were positive for HBsAg. Though the prevalence of australia antigen was slightly higher in borderline tuberculoid, borderline borderline and tuberculoid cases, it is not statistically significant. No association between carriership of HBsAg and lepromatous leprosy could be found in the present study.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 2","pages":"193-6"},"PeriodicalIF":0.0,"publicationDate":"1983-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17687784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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