{"title":"Social and personality factors in dapsone resistant patients.","authors":"J K John, V K Pannikar, A Verghese, M Christian","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A preliminary study in which a sample of 25 patients registered with SLR and TC, Karigiri, with proved secondary DDS-resistant leprosy were compared, with 25 patients not suspected to be DDS-resistant, for social and personality factors, which could have lead to non-compliance in treatment. A structured interview schedule enquiring into factors leading to irregular treatment and the psycho-social background of the patient was used. The Eysank's Personality Inventory (EPI) and Personality traits assessment on a linear analogue was also administered to them. Statistical analysis showed that DDS-resistant leprosy patients were as a group more irregular for treatment, showed personality traits of being casual and uncontrolled and scored high on the neuroticism scale of the EPI.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 1","pages":"100-6"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17926028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Leprosy vaccine--a puzzle.","authors":"C K Job","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17409132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J R Kher, P S Baji, S K Ganeriwal, B V Reddy, P M Bulakh
{"title":"Serum lipoproteins in lepromatous leprosy.","authors":"J R Kher, P S Baji, S K Ganeriwal, B V Reddy, P M Bulakh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serum total cholesterol and the lipoprotein fractions were studied in forty subjects of lepromatous leprosy and age matched controls. The study revealed a significant decrease in serum cholesterol in the disease group as compared to control group. The decrease in cholesterol was 28.76% An alteration in serum lipoprotein fractions was observed in disease group. The beta-lipoprotein fraction showed a significant decrease along with a rise in alpha-lipoprotein fraction. A positive correlation was also observed between total cholesterol and beta-lipoproteins. The significance of the above findings are discussed.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 1","pages":"80-5"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17925949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serological study for presence of C-reactive protein, rheumatoid factor, anti streptolysin O in leprosy cases.","authors":"V N Bhatia, S Balakrishnan, S Harikrishnan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serological tests for the detection of C-reactive protein (CRP), Rheumatoid factor (RE) and Anti Streptolysin 'O' (ASLO) antibodies employing latex test were carried out in 120 cases of active lepromatous leprosy, 14 LL cases with ENL during active and subsided phases and 25 controls. Out of 120 LL cases 25.8% gave a positive reaction to CRP and ASLO. Only 4.2% of the cases with LL were positive for Rheumatoid factor. None of the controls showed positive reaction in these tests. During ENL, 100% of the sera showed positive test for CRP as against 35.7% during subsidence of reaction. Tests for RF were positive in 28.5% of the cases ENL as compared to none during subsided ENL. Raised ASLO titers were noticed in 38.2% cases with active ENL as against 21.4% during subsided phase of ENL.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 1","pages":"86-90"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17925950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dapsone compliance in an urban field project.","authors":"C R Revankar, S S Naik, R Ganapati","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Available reports both from rural and urban leprosy centres prove beyond any doubt that dapsone is not being consumed regularly by all those who show regular clinic attendance. No reports are available from urban field projects where SET programme is being operated. In this study surprise urine samples of 294 patients of all types (smear positive 53%) mainly on dapsone monotherapy attending (1) leprosy treatment centres in slum clinics situated in the field areas adopted for SET work by Bombay Leprosy Project and (2) general hospital clinics situated predominantly outside the project area were analysed for dapsone/creatinine ratio to judge the extent of drug compliance. 201 out of 294 (68%) were regular and 82 out of 294 (28%) were irregular in consuming DDS as judged by urine examination. 67% of smear positive cases were regular. No difference was found in regularity between patients living within the project area (intensive follow up is done in this group to remind about treatment) and outside project area patients (no reminder followup is done). Similarly no difference was observed in regularity amongst the patients attending slum clinics and general hospital clinics. It could be stated that facilities for treatment offered at general hospitals or dispensaries and encouraging voluntary reporting could be quite fruitful and economical for obtaining better drug compliance in urban areas.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 1","pages":"117-21"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17926031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Variations in the readings of B.I. and M.I.","authors":"Gjalt","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 1","pages":"181-6"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17926035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacillary clearance in a lepromatoid nude mouse following an infection with mouse hepatitis virus.","authors":"C K Job, S Chehl, R C Hastings","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 1","pages":"177-8"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17370029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vaccines against leprosy.","authors":"G P Talwar","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 1","pages":"8-11"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17409136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N K Ganguly, B Kumar, S Kaur, C Vaishnavi, R N Chakravarti
{"title":"Lymphocyte subpopulations in mice infected with Mycobacterium leprae.","authors":"N K Ganguly, B Kumar, S Kaur, C Vaishnavi, R N Chakravarti","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>T and B cells were quantitated from the spleen of M. leprae infected mice and correlated with bacillary count in the foot pad. Lymphocyte transformation with PHA and M. leprae (armadillo) antigens was also studied during different months of infection. T cell counts dropped gradually but significantly throughout the course of infection. B cells had a concomitant rise up to 6 months and then registered a fall as compared to the initial control figures. Transformation of lymphocytes with PHA fell significantly after 4th month til the end of the experiment, whereas stimulation index for armadillo antigen rose gradually from 3rd month onwards to reach a peak at 6th month and then fell till the end of the experiment with increasing bacterial population whereas B-cell counts showed little change.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 1","pages":"29-38"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17660248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Taxonomic studies on Mycobacterium leprae.","authors":"A M Dhople","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>M. leprae harvested from livers and spleens of infected armadillos showed close similarity in biochemical characteristics with M. vaccae than with any other cultivable mycobacteria. Further more. M. lepraemurium was least similar to M. leprae. Thus, M. leprae can be linked with fast-growing groups of acid-fast bacilli, and perhaps most closely with the M. vaccae complex.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 1","pages":"39-44"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17409134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}