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The effect of clofazimine on liver function tests in lepra reaction (ENL). 氯法齐明对麻风反应(ENL)患者肝功能的影响。
Leprosy in India Pub Date : 1983-10-01
P M Bulakh, C N Kowale, S M Ranade, N P Burte, A G Chandorkar
{"title":"The effect of clofazimine on liver function tests in lepra reaction (ENL).","authors":"P M Bulakh,&nbsp;C N Kowale,&nbsp;S M Ranade,&nbsp;N P Burte,&nbsp;A G Chandorkar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Twenty patients with suspected DDS resistance and repeated attacks of lepra reactions were selected for the study. Clofazimine was administered in different doses over a period of 12 months. Elevated levels of transaminases and Alkaline phosphatase prior therapy attained values to near normalcy. Progressive fall in serum Bilirubin and Proteins with normal A/G ratio at the end of therapy was also observed. Clofazimine by its anti-inflammatory and antibacterial action could inhibit the process of liver damage and happened to have minimal deleterious effect on liver by studying the liver function tests.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 4","pages":"714-8"},"PeriodicalIF":0.0,"publicationDate":"1983-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17723512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinico-pathological study of lymph node involvement in leprosy. 麻风病淋巴结累及的临床病理研究。
Leprosy in India Pub Date : 1983-10-01
H K Kar, H C Mohanty, G N Mohanty, U P Nayak
{"title":"Clinico-pathological study of lymph node involvement in leprosy.","authors":"H K Kar,&nbsp;H C Mohanty,&nbsp;G N Mohanty,&nbsp;U P Nayak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One hundred and five leprosy patients including 37 cases of LL and LI, 22 cases of BL, 3 cases of BB, 17 cases of BT, 23 cases of TT and 3 cases of indeterminate type during the period of 1980-81 have been examined clinically. All the patients of LL, LI, BL and BB types, 94% of BT, 70% of TT and 66.6% of indeterminate type have showed clinical enlargement of lymph nodes. In order of frequency the enlarged nodes are inguinal (76.2%) cervical (69.5%), axillary (69.5%), epitrochlear (64.7%) and lastly pre-auricular (9.5%). Although both regional and distant groups of lymph node enlargement have been observed in all cases of LL, LI and BL, in majority of the non-lepromatous cases there is only involvement of regional lymph nodes. Biopsies of lymph nodes are made from 51 leprosy patients, 22 from LL and LI cases, 11 from BL cases, 2 from BB cases, 8 from BT cases, 6 from TT cases and 2 from indeterminate leprosy cases. Major histopathological changes have been studied in different types of leprosy. The humoral antibody response and the cellular immune response are well reflected on the histopathological finding of the lymph nodes belonging to different immunological spectrum of leprosy patients. The examination of lymph nodes is recommended as a useful adjunct for the diagnosis and classification of leprosy.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 4","pages":"725-38"},"PeriodicalIF":0.0,"publicationDate":"1983-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17723514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Repeal of the Lepers Act, 1898. 废除麻风病人法案(1898年)
Leprosy in India Pub Date : 1983-10-01
Dharmendra
{"title":"Repeal of the Lepers Act, 1898.","authors":"Dharmendra","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 4","pages":"633-9"},"PeriodicalIF":0.0,"publicationDate":"1983-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17723675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
'Frustration--anxiety behaviour as a function of leprosy patients age and personality'. “沮丧——焦虑行为与麻风病患者的年龄和性格有关。”
Leprosy in India Pub Date : 1983-10-01
N S Chauhan, U Dhar, S Chauhan
{"title":"'Frustration--anxiety behaviour as a function of leprosy patients age and personality'.","authors":"N S Chauhan,&nbsp;U Dhar,&nbsp;S Chauhan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The paper incorporates five studies (i.e., four of frustration and one of anxiety). The design is 'Multi-group-Control-group'. Each one of the five studies has four '3 X 3 X 2' factorial experiments. Each experiment has 360 elements. These are three groups (of lepromatous, non-lepromatous and of disease-free normals). Each group consists of 120 elements (equally distributed among adolescents, adults and senescents). The particulars of the patients have been obtained from the Central JALMA Institute for Leprosy and the Kushta Seva Sadan (Agra). The disease-free normal elements are drawn freely from the population of the Agra town. The sample possesses statistical justification for size and representativeness. Data are collected with the help of reliable tools and the 'F' test is run for verification of the 'null hypotheses'. Results show that experiences of 'fixation-regression' frustration, atypically belong to normal senescence. Resignation and anxiety experiences, as growing hazards, specifically relate to leprosy patients. Personality factors that normally demote 'frustration-anxiety' behaviour exhibit 'role-negation' in the leprosy patients. Age shows 'role-reversion'. Implications of such 'role' changes relate to the 'self-eroding' process of personality in the patients.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 4","pages":"743-51"},"PeriodicalIF":0.0,"publicationDate":"1983-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17724415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Composite skin contact smears in multi-bacillary leprosy patients. 多菌性麻风病患者的复合皮肤接触涂片。
Leprosy in India Pub Date : 1983-10-01
V Periaswami
{"title":"Composite skin contact smears in multi-bacillary leprosy patients.","authors":"V Periaswami","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 4","pages":"780"},"PeriodicalIF":0.0,"publicationDate":"1983-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17426598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Further modification on the haemolysis method in determining bacteraemia in leprosy patients. 溶血法测定麻风病菌血症的进一步改进。
Leprosy in India Pub Date : 1983-10-01
U Sengupta, G Ramu, K V Desikan
{"title":"Further modification on the haemolysis method in determining bacteraemia in leprosy patients.","authors":"U Sengupta,&nbsp;G Ramu,&nbsp;K V Desikan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bacteraemia was assessed and compared in the venous blood samples of leprosy patients by employing the existing and the modified haemolysis method respectively. The modified method was more sensitive in determining bacteraemia in these patients as evident from the finding of more number of positive cases detected by this method. A significantly higher yield of bacterial number was detected by employing the present method when compared to that obtained by earlier method.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 4","pages":"670-4"},"PeriodicalIF":0.0,"publicationDate":"1983-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17723504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A study of clinico-histologic correlation in lesions of borderline leprosy with multiple skin biopsies from different sites. 边缘性麻风病病变与不同部位多次皮肤活检的临床组织学相关性研究。
Leprosy in India Pub Date : 1983-10-01
S Gupta, R Singh, B Iyengar, B S Reddy
{"title":"A study of clinico-histologic correlation in lesions of borderline leprosy with multiple skin biopsies from different sites.","authors":"S Gupta,&nbsp;R Singh,&nbsp;B Iyengar,&nbsp;B S Reddy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>20 active untreated cases of borderline leprosy were subdivided on clinical, bacteriological and immunological grounds. None had reactional episodes. Multiple skin biopsies from each one of them showed varied histopathology from different lesions. 84 out of 93 biopsies (90.3%) were found not to be in agreement with the clinical diagnosis. Even the multiple biopsies obtained from single large lesion revealed varied histopathological picture. The reason for the histopathological disparity has been postulated.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 4","pages":"686-93"},"PeriodicalIF":0.0,"publicationDate":"1983-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17723507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Special features of physical therapy in the claw hand of leprosy. 物理治疗中爪手麻风的特殊特点。
Leprosy in India Pub Date : 1983-10-01
V N Kulkarni, J M Mehta
{"title":"Special features of physical therapy in the claw hand of leprosy.","authors":"V N Kulkarni,&nbsp;J M Mehta","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This article emphasizes the vital role of a physical therapist in the surgical programme of the correction of clawing caused in leprosy due to paralysis of intrinsics. Right from the assessment of patient till the final re-education a physical therapist is a must helping in motivating the patient, planning the type of procedure to be performed on him and training the patient post-operatively. If treated early a physical therapist himself can overcome the deformity by the help of various physical therapy measures without surgical intervention.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 4","pages":"694-6"},"PeriodicalIF":0.0,"publicationDate":"1983-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17723508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short course treatment of tuberculoid cases--a feasibility study. 结核病例短期治疗的可行性研究。
Leprosy in India Pub Date : 1983-10-01
B K Girdhar, A Girdhar, G Ramu, K V Desikan
{"title":"Short course treatment of tuberculoid cases--a feasibility study.","authors":"B K Girdhar,&nbsp;A Girdhar,&nbsp;G Ramu,&nbsp;K V Desikan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>With an aim to reduce the length of treatment of leprosy, as a first step an investigation has been undertaken to evaluate the efficacy of maintenance therapy in non-lepromatous cases. Relapse rates in a group of 47 cases, in whom treatment had been given only til the point of inactivity (the trial group) have been compared with a similar group of 27 cases who received additional 18 months maintenance therapy (the control group). No difference in relapse rates has been found (2.13 per 1000 patient months in trial group as against 2.58 per 1000 patient months in the control group). This suggests that additional 18 months maintenance therapy, as is currently recommended, does not offer any additional advantage in reducing the relapses.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 4","pages":"719-24"},"PeriodicalIF":0.0,"publicationDate":"1983-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17723513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of "tile reaction" test for screening dapsone in urine. “瓦反应”试验筛选尿中氨苯砜的应用。
Leprosy in India Pub Date : 1983-10-01
P P Irudaya Raj, L Lilly, M Aschhoff, S Balakrishnan
{"title":"Application of \"tile reaction\" test for screening dapsone in urine.","authors":"P P Irudaya Raj,&nbsp;L Lilly,&nbsp;M Aschhoff,&nbsp;S Balakrishnan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A modified tile reaction test for monitoring self administration of DDS by leprosy patients is described. 385 Urine samples collected at 24 hours after a single dose and at 24, 48 and 72 hours after daily doses of 25, 50, 100 mg were screened for the presence of DDS by this test and the corresponding DDS/C ratios were studied for comparison. Patients compliance was assessed on 268 urine specimens collected on surprise visits. The feasibility of application of this test in field situations is discussed.</p>","PeriodicalId":76113,"journal":{"name":"Leprosy in India","volume":"55 4","pages":"654-64"},"PeriodicalIF":0.0,"publicationDate":"1983-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17723677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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